ライフサイエンスコーパス: corrin

1 raction mechanisms that convert porphyrin to corrin.

2 t X-ray crystallographic structure of a zinc corrin.

3 he current views concerning the evolution of corrins.

4 e 26-kDa polypeptide at a molar ratio of 1.1 corrin/26-kDa polypeptide.

5 The light-responsive cobalt-corrin AdoCbl performs this nonenzymatic role by facilit

6 idistant between the hydrogenation levels of corrin and corrole, is enantiomeric, and contains two ge

7 nstrate straightforward applicability of the corrin-based chemosensor, aquacyanocobyrinic acid (ACCA)

8 theory (TD-DFT) calculations indicates that corrin-based pi --> pi transitions, which dominate the C

9 with the same avidity as observed with other corrin biosynthetic transmethylases.

10 determined bond strength in a series of aryl-corrins by the threshold collision-induced dissociation

11 nbl), the Zn-analogues of the natural cobalt-corrins cobyric acid and vitamin B(12) , respectively.

12 n the literature based on lipophilic Co(III)-corrin complexes, allowing the new nitrite electrodes to

13 -deoxyadenosine and attachment of 1 equiv of corrin covalently to an active-site cysteine residue of

14 d rotation of the Ado ligand relative to the corrin gave rise to four locally minimum structures with

15 roles include chlorophylls, hemes, siroheme, corrins (including vitamin B(12)), coenzyme F(430), heme

16 bound to RNR and 0.25 equiv of a cobalt(III) corrin is tightly associated, likely through a covalent

17 Proteolysis of corrin-labeled RTPR with endoproteinase Glu-C and peptid

18 Consequently, the corrin ligand coordinates cobalt ions in desymmetrized "

19 l revealed a conspicuously better fit of the corrin ligand for Rh(III) than for Co(III) , challenging

20 Niby shows the structural adaptation of the corrin ligand to Ni(II) ions and the coordination behavi

21 two inner protons bound at N2 and N4 of the corrin ligand, as discovered in Hby.

22 primordial selection and evolution of their corrin ligand.

23 D spectra suggest the cobalt exists as a non-corrin low-spin Co3+ ion in a tetragonally-distorted oct

24 attached to one of the pyrrole rings of the corrin macrocycle via an aminopropanol moiety.

25 d that, during anaerobic biosynthesis of the corrin macrocycle, the two-carbon fragment excised from

26 ts favorable orientation with respect to the corrin macrocycle, which minimizes steric repulsion duri

27 found to resemble the corresponding Co(II) -corrins, making such Zn-corrins potentially useful for i

28 rt the biosynthesis of the cobalt-free B(12) corrin moiety, hydrogenobyric acid (Hby), a compound cra

29 The related Ni(II) corrin nibyric acid (Niby) was similarly synthesized fro

30 hlorovinylcobalamin models also involves the corrin pi* orbital, but reduction of the base-off dichlo

31 00 nm) assigned to Co 3d --> 3d or Co 3d --> corrin pi* transitions and by visible absorption bands s

32 d by visible absorption bands similar to the corrin pi-->pi* transitions observed for ground state Cb

33 zation of the Co 3d orbitals relative to the corrin pi/pi*-based molecular orbitals when Co2+ Cbl is

34 orresponding Co(II) -corrins, making such Zn-corrins potentially useful for investigations of B(12) -

35 Aryl corrins represent a novel class of designed B(12) deriva

36 The second set is assigned to the corrin ring (14)N nuclei.

37 on is eliminated by placing that face of the corrin ring adjacent to a cluster of bulky hydrophobic s

38 cleavage is followed by reorientation of the corrin ring and a switch from a lower to upper histidine

39 actions with the e- and f-side chains of the corrin ring and is conserved in corrinoid-binding protei

40 auxotroph, a Roseovarius sp., to produce the corrin ring and synthesize B(12).

41 of the 1-amino-2-propanol side chain of the corrin ring and the subsequent attachment of GMP to form

42 eveal that many of the interactions with the corrin ring are conserved among the human Cbl transporte

43 obalamin is sensitive to modification of the corrin ring b-propionamide of cyanocobalamin.

44 mide-phosphate, the last step of the de novo corrin ring biosynthetic branch of the adenosylcobalamin

45 ity to salvage cobyric acid (Cby), a de novo corrin ring biosynthetic intermediate, under aerobic gro

46 (encoding an essential enzyme of the de novo corrin ring biosynthetic pathway) resulted in a strain o

47 zole tail splayed into a side pocket and its corrin ring buried.

48 the environment around the alpha face of the corrin ring consists of bulky hydrophobic residues.

49 Corrination is the conjugation of a corrin ring containing molecule, such as vitamin B(12) (

50 Two pathways for corrin ring formation have been found-an aerobic pathway

51 linkage between the nucleotide loop and the corrin ring in cobalamin.

52 The corrin ring is considerably flatter than that of AdoCbl,

53 The corrin ring is oriented such that the cobalt atom is loc

54 Although the corrin ring of vitamin B12 is unable to efficiently abso

55 e bacterium Salmonella enterica produces the corrin ring only under anaerobic conditions, but it can

56 nt intermediate state can be attributed to a corrin ring pi to Co 3d(z2) ligand to metal charge trans

57 ne another since electron attachment is to a corrin ring pi-orbital, whose energy is relatively unaff

58 m bond on a 110 fs time scale is followed by corrin ring relaxation on a 260 fs time scale.

59 Thus, the equatorial corrin ring sterically impedes binding, making Co(II)Cbi

60 lamin (Cbl), a dietary cofactor containing a corrin ring that coordinates a Co(3+) ion, was identifie

61 the protein and the polar side chains of the corrin ring which accounts for the broad specificity of

62 dimethylbenzimidazole tail tucked under the corrin ring, displacing the N terminus of ATR, which is

63 on the Ado group and to a lesser extent the corrin ring.

64 -ordination bonds with the cobalt ion of the corrin ring.

65 pproximately 70 degrees to the normal of the corrin ring.

66 ions between (Z)-chloro substituents and the corrin ring.

67 llates from perpendicular to parallel to the corrin ring.

68 he nucleotide loop in the alpha phase of the corrin ring.

69 nd the Ade is virtually perpendicular to the corrin ring; in the minor conformer, the Ade is tilted d

70 lbenzimidazole nucleotide substituent of the corrin ring; when methylcobalamin binds to methionine sy

71 synthesis relates to its distinctive cobalt corrin structure, which is essential for B12 biochemistr

72 y allowed the unprecedented observation of a corrin triplet (E(T) =190 kJ mol(-1) ) and was found to

73 the side chains around the periphery of the corrin unit.

74 Nibl, and corresponding isoelectronic Co(I) corrins, were deduced to be isostructural.