ライフサイエンスコーパス: corrole

1 rphyrinoids (porphodimethene, porphyrin, and corrole).

2 e(V) are TsNH(2) and the trivalent manganese corrole.

3 r knowledge, of O(2) binding to a cobalt(II) corrole.

4 age compared with the systemically delivered corrole.

5 les are dramatically altered from the parent corroles.

6 -metal corroles, and finally f-block element corroles.

7 ization to afford a new class of trans-A(2)B-corroles.

8 2)-corrole(a2u) interaction in coinage metal corroles.

9 us methodologies leading to meso-substituted corroles.

10 -oxo bond in high-valent Cr(IV) versus Cr(V) corroles.

11 tpfc)Mn (tpfc=5,10,15-tris(pentafluorophenyl)corrole), 1, affords the high-valent (tpfc)MnV=NTs, 2, o

12 tives of gallium(III) tris(pentafluorophenyl)corrole, 1 [Ga(tpfc)], with either sulfonic (2) or carbo

13 lectronic structures as well as full-fledged corrole(*2-) radicals among corrole derivatives.

14 Carboxylated corroles 3 and 4, which exhibited about 10-fold lower IC

15 Less commonly encountered is the metal(dpi)-corrole("a1u") interaction, a unique feature of formal d

16 in Mn and Fe corroles) and the metal(dx2-y2)-corrole(a2u) interaction in coinage metal corroles.

17 transition-metal corroles are the metal(dz2)-corrole("a2u") interaction (most commonly observed in Mn

18 II) or Ga(III) into an imidazole-substituted corrole affords an exceptionally robust photoactive dime

19 containing a Co(II) porphyrin and a Co(III) corrole also linked by one of the above rigid spacers (Y

20 gated (tpfc = 5,10,15-tris(pentafluorophenyl)corrole and Ts = p-toluenesulfonate).

21 ibing advances in the synthetic chemistry of corroles and selected applications in which corroles are

22 raction (most commonly observed in Mn and Fe corroles) and the metal(dx2-y2)-corrole(a2u) interaction

23 nd iron) and porphyrinoid ligand (porphyrin, corrole, and corrolazine).

24 ex 2 is the first well characterized Fe-O(2) corrole, and mediates the following biologically relevan

25 bling) are applicable to reactions affording corrole, and to explore the requirements of the oxidatio

26 t corrole derivatives, then transition-metal corroles, and finally f-block element corroles.

27 < Fe < Al < Mn < Sb < Au for bis-sulfonated corroles; and, importantly, that they correlate with met

28 is a first crystal structure of a free-base corrole anion, derived from tris(p-cyanophenyl)corrole,

29 Hangman cobalt corroles are furnished in good yields from a one-pot con

30 Sulfonated gallium(III) corroles are intensely fluorescent macrocyclic compounds

31 corroles and selected applications in which corroles are key components.

32 We conclude that carboxylated gallium corroles are promising chemotherapeutics with the advant

33 ting ligand noninnocence in transition-metal corroles are the metal(dz2)-corrole("a2u") interaction (

34 Corroles are versatile chemically active agents in solut

35 ported in the literature, related molybdenum corroles are very less reported.

36 modalities, here we have explored the use of corroles as contrast enhancing agents for magnetic reson

37 s part of our efforts to develop rhenium-oxo corroles as photosensitizers for oxygen sensing and phot

38 rrole anion, derived from tris(p-cyanophenyl)corrole, as the tetrabuylammonium salt.

39 eterocorroles, 22-heterocorroles, N-confused corroles, as well as norcorroles.

40 d EPR spectra and DFT calculations of cobalt corrole axially ligated by chloride are consistent with

41 The resultant corrole-based COF, TPAPC-COF, exhibits high crystallinit

42 cessful synthesis of a novel two-dimensional corrole-based covalent organic framework (COF) by reacti

43 inoids, L2-L4, possessing different types of corrole-based frameworks were synthesized from a pyrrole

44 To provide a suitable reference for other corrole-based systems on surfaces, we chose the archetyp

45 lations were established by studying the new corroles-based photodynamic therapy (PDT) in human lung

46 rther demonstrated by the synthesis of three corroles bearing different meso substituents in defined

47 Cobalt hangman corrole, bearing beta-octafluoro and meso-pentafluorophe

48 xploited to analyze the different aspects of corrole binding.

49 1,3-dipolar cycloaddition yielding the first corrole-BODIPY heterodimer involving the pentafluorosulf

50 (II)-metal complexes, A3-, A2B- and AB2-type corroles, BODIPYs, and their dipyrrane precursors was st

51 ce were cobalt(II) porphyrin and cobalt(III) corrole-both characterized by a high stability of the co

52 mination proved slower relative to Cu and Ir corroles, but the desired Re[Br(8)TpXPC](O) products wer

53 aled facile uptake of functionalized gallium corroles by all human cancer cells that followed the ord

54 upling between an S = (3/2) Mn(II) ion and a corrole-centered radical cation: [Mn(II)C(*)(2-)].

55 ures and reactions of all well characterized corrole-chelated d- and p-block metal complexes, includi

56 Corrole chemistry has witnessed an impressive boost in s

57 The renaissance in corrole chemistry is strongly correlated with synthetic

58 c of debate and revision since the advent of corrole chemistry.

59 lding blocks in the synthesis of porphyrins, corroles, chlorins, calix[4]pyrroles, porphodimethenes,

60 ow show that water oxidation with the cobalt-corrole CoBr(8) as electrocatalyst affords H(2)O(2) as t

61 A synthetic route to trans-A(2)B-corroles combining the macrocyclic core with a hydrazone

62 n of an organic acid to the manganese(V)-oxo corrole complex (tpfc)Mn(V)(O) (tpfc = 5,10,15-tris(pent

63 eak interactions in a representative Au(III)-corrole complex point out that these complexes are capab

64 Systemic delivery of this protein-corrole complex results in tumor accumulation, which can

65 d by alternately linking Mn-porphyrin and Fe-corrole complexes.

66 ns underscore ligand non-innocence in copper corrole complexes.

67 ansfer (ET) and hole transfer (HT) between a corrole (Cor) donor linked to a perylene-diimide (PDI) a

68 s, we found that the yield and purity of the corrole depend on judicious selection of oxidation condi

69 The absorption feature of these modified corrole derivatives (both position and intensity) bears

70 ears, thanks to the possibility of preparing corrole derivatives by simple synthetic procedures.

71 Corrole derivatives exhibit a rich array of optical prop

72 sed on the potential for the exploitation of corrole derivatives in different important application f

73 nyl moiety of a trans-A2B2-porphyrin and two corrole derivatives with a mixed substitution pattern in

74 Like porphyrins, corrole derivatives with a redox-inactive coordinated at

75 describing free-base and main-group element corrole derivatives, then transition-metal corroles, and

76 ections of electronic-structural research on corrole derivatives.

77 as full-fledged corrole(*2-) radicals among corrole derivatives.

78 nsive account of the electronic structure of corrole derivatives.

79 han untargeted systemic doxorubicin, and the corrole did not damage heart tissue.

80 The photophysical properties of Ir(III) corroles differ from those of phosphorescent porphyrin c

81 Additionally, the corrole elicited tumor-toxicity through the loss of mito

82 aled efficient fluorescence quenching of the corrole entity in the dyads.

83 We have found that a manganese-metallated corrole exhibits significant T1 relaxation shortening an

84 A new structurally characterized ferrous corrole [Fe(II) (ttppc)](-) (1) binds one equivalent of

85 be visualized in vivo owing to intensely red corrole fluorescence.

86 an overview of the different applications of corroles, focusing on the studies reported in the last f

87 first example of covalently linked free-base corrole-fullerene dyads is reported.

88 The sulfonated gallium(III) corrole functions both for tumor detection and intervent

89 ximately T-shaped 5,10,15-tris(p-aminophenyl)corrole H(3) TPAPC with terephthalaldehyde, which adopts

90 products, including [15]triphyrin(1.1.3) H3, corrole H(3)4, porphyrin H(2)2, [24]pentaphyrin(1.1.1.1.

91 he archetypal 5,10,15-tris(pentafluorophenyl)corrole [H(3)(TpFPC)] as model system, weakly adsorbed o

92 ground state electronic structure of copper corroles has been a topic of debate and revision since t

93 In some areas, the potential of corroles has been studied in certain detail, for example

94 The investigation of a large number of corroles has highlighted some peculiar characteristics o

95 Corroles have come a long way from being a curiosity to

96 Free-base corroles have long been known to be acidic, readily unde

97 with a water-soluble bis-sulfonated gallium corrole in both cellular and rodent-based models.

98 lt metathesis with the corresponding lithium corrole in remarkably high yields (93% and 83%, respecti

99 omatic substitution and the participation of corroles in cycloaddition reactions as 2pi or 4pi compon

100 yanatocorroles are different from the parent corroles in many ways.

101 its infancy, such as in the exploitation of corroles in solar cells.

102 Other functionalizations of corroles include a large diversity of reactions, namely

103 isomer isonorrole and finally to N-confused corrole indicate that multiply fused porphyrinoids could

104 V)(O) (tpfc = 5,10,15-tris(pentafluorophenyl)corrole) induces valence tautomerization resulting in th

105 The corrole is planar in both cases (the mean deviation from

106 T catalysis by high-valent oxochromium(IV,V) corroles is to be elucidated.

107 tween the hydrogenation levels of corrin and corrole, is enantiomeric, and contains two geminal dimet

108 ion of a new class of compounds--the hangman corroles--is provided efficiently by the modification of

109 were synthesized from a pyrrole-substituted corrole isomer (norrole L1).

110 ve singly and doubly N-CAr -fused N-confused corroles, L3 and L4, respectively.

111 examples of actinide complexes incorporating corrole ligands are presented.

112 ecent intense interest regarding the role of corrole ligands in stabilizing high oxidation states.

113 unique fundamental features that distinguish corrole ligands, among them outstanding electron donatio

114 HBCP has a corrole-like trianionic core that is capable of coordina

115 nvolving oxidation and ring expansion of the corrole macrocycle are described comprehensively.

116 that despite the molecular asymmetry of the corrole macrocycle, the electronic structure of the Mn(I

117 s has imparted significant distortion to the corrole macrocycle.

118 center residing in the one-electron oxidized corrole macrocycle.

119 A new method of activating corrole macrocycles via an in situ generated SCN radical

120 d in certain detail, for example, the use of corrole metal complexes as electrocatalysts for energy c

121 ic properties of surface-supported free-base corrole molecules.

122 and therapeutic efficacy of a tumor-targeted corrole noncovalently assembled with a heregulin-modifie

123 of DU-145 prostate cancer cells treated with corrole NPs (<=100 nM) revealed fast cellular uptake, ve

124 The physical properties of corrole NPs prepared in combination with transferrin and

125 ives, seminal examples of the application of corroles or other porphyrin analogues are evidenced in d

126 The protein-corrole particle (which we call HerMn) exhibited improve

127 The tumor-targeted corrole particle, HerGa, displays preferential toxicity

128 groups at the axial positions makes iridium corroles particularly exciting as PDT drug candidates.

129 We now introduce the difluorophosphorus(V) corrole PC-Im, a theranostic agent with a pH-sensitive N

130 Ir(III) corrole phosphorescence is observed at ambient temperatu

131 vity toward light of dilute solutions of the corroles prepared in this study.

132 With this progress in the elucidation of corrole properties, attention has been focused on the po

133 Our method of preparation of corrole/protein NPs may be generalizable to many bioacti

134 with an antiferromagnetically coupled Cu(II) corrole radical cation ground state.

135 The corrole radical cation manganese(IV) hydroxo complex has

136 genation of five ReO meso-tris(para-X-phenyl)corroles, Re[TpXPC](O) (X = CF(3), H, F, CH(3), and OCH(

137 to an intrinsic pseudorotational mode of the corrole ring about the M-M axis.

138 In each case, the corrole ring showed a large distortion from planarity, w

139 The hangman corroles show enhanced activity for the selective reduct

140 The solvatochromic behavior of Ir(III)-corrole Soret and Q absorption bands suggests that the l

141 nd strong through-space interactions between corrole subunits inferred from spectroscopic and electro

142 yntheses of isocorroles and heteroanalogs of corroles such as triazacorroles (corrolazines), 10-heter

143 ferential formation of octaphyrin instead of corrole suggests that the anti conformation of 2,2'-bipy

144 systems requires a fundamental knowledge of corrole-surface interactions.

145 The 1999 discovery of one-pot corrole synthesis opened the floodgates for research on

146 ew we present a comprehensive description of corroles' synthesis, developed both before and after 199

147 es with the cobalt(II) porphyrin/cobalt(III) corrole system are promising alternatives for existing t

148 s shown that an iron(III) meso-N-substituted corrole (TBP(8)Cz)Fe(III) (1) (TBP(8)Cz = octakis(4-tert

149 lium(III) complex of a minimally substituted corrole that is coated by transferrin as a targeting veh

150 ur story highlights the unique properties of corroles that have made them the molecular components of

151 However, in corroles, the S = 1 (intermediate-spin) state is much lo

152 Iridium corroles thus may hold promise as photosensitizers in ph

153 interaction between new tri-N-methylpyridyl corrole (TMPC) and its germanium(IV) derivative (GeTMPC)

154 in concert with the redox properties of the corrole to enhance the catalytic activity of O-O bond ac

155 n transfer from the excited singlet state of corrole to the fullerene entity.

156 Mn(III) porphyrins, and a different Mn(III) corrole, [(tpfc)Mn(OPPh(3))], previously studied by HFEP

157 erivatives of 5,10,15-tris(pentafluorophenyl)corrole (tpfpc) are shown to provide useful information

158 greatly enhanced compared to other Fe or Mn corroles under similar catalytic conditions, consistent

159 In the case of the diamagnetic thorium corrole, variable-temperature, DOSY (diffusion-ordered)

160 As an example, one functionalized corrole was further reacted with an azido-substituted BO

161 tuted [34]octaphyrin(1.1.1.0.1.1.1.0) and/or corrole was investigated to determine the effect of key

162 ly, the electronic structure of the actinide corroles was assessed using UV-vis spectroscopy, cyclic

163 >> 1 (intracellular accumulation of gallium corroles was fastest in melanoma cells).

164 ols with pyrrole leading to meso-substituted corroles was investigated to determine whether mild acid

165 nce with the detection and isolation of some corroles, we found that the yield and purity of the corr

166 and uranium(IV) macrocycles of Mes2(p-OMePh)corrole were synthesized via salt metathesis with the co

167 The methyl-hydrazone corroles were more active than phenyl-hydrazone corroles

168 Three series of cobalt(III) corroles were tested as catalysts for the electroreducti

169 In our view, research on corroles will continue to grow by leaps and bounds, most

170 Computational studies formulate neutral Cu corroles with an antiferromagnetically coupled Cu(II) co

171 Water-soluble corroles with inherent fluorescence can form stable self

172 roles were more active than phenyl-hydrazone corroles, with the N-Boc and N-Ts groups being key struc

173 pXPC)]L(2), where TpXPC = tris(para-X-phenyl)corrole (X = CF(3), H, Me, and OCH(3)) and L = pyridine