戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1  from the cell surface, rather than from the cortical granules.
2 ertilization are driven by the exocytosis of cortical granules.
3 f the ras superfamily, rab3, were present on cortical granules.
4 o hyalin, a protein packaged specifically in cortical granules.
5  extracellular surface of the egg and to the cortical granules.
6 zation some of the antigens are localized to cortical granules.
7 t with exocytosis of proteoglycan-containing cortical granules.
8  underlying the oolemma, deep to the zone of cortical granules.
9 tosis, myosin 1e relocates to the surface of cortical granules.
10 of the overexpressed csp was associated with cortical granules.
11 onsistent with the dynamics of exocytosis of cortical granules.
12 opulation of targets for cleavage within the cortical granules.
13 les in the egg cortex that are distinct from cortical granules.
14 with Lens culinaris agglutinin, a marker for cortical granules.
15 e followed by positional quantitation of the cortical granules.
16 heral Golgi complexes, and a failure to form cortical granules.
17                           In the sea urchin, cortical granules accumulate throughout the cytoplasm du
18                             We discover that cortical granule anchoring in the cortex is dependent on
19    Ovastacin is a pioneer component of mouse cortical granules and plays a definitive role in the pos
20  to the plasma membrane impairs secretion of cortical granules and results in polyspermy.
21 s occur because of defects in trafficking of cortical granules and the subsequent formation of an imp
22 only when secreted, due to the low pH of the cortical granules, and it has a small population of targ
23 d in specialized secretory organelles called cortical granules, and PmARCs accumulated in a different
24 rchin egg, in which thousands of homogeneous cortical granules are associated with the plasma membran
25      In the in vitro-matured egg, 99% of the cortical granules are at the cortex, indistinguishable f
26 asm during oogenesis, but in mature eggs the cortical granules are attached to the plasma membrane, h
27 ertilization in sea urchins, the contents of cortical granules are secreted and rapidly assemble into
28                                              Cortical granules are secretory vesicles poised at the c
29                                              Cortical granules are specialized organelles whose conte
30                                              Cortical granules are synthesized throughout oogenesis a
31 e, is maternally derived and exocytosed from cortical granules at fertilization.
32                    However, just after GVBD, cortical granules attach to microfilaments and transloca
33 pecific antiserum, ovastacin was detected in cortical granules before, but not after, fertilization.
34 ected vesicle hitchhiking mechanism by which cortical granules bind to Rab11a vesicles powered by myo
35                  We determined the pH of the cortical granule by fluorescent indicators and micro-pH
36 peared from these structures and appeared on cortical granules by anaphase I.
37 active forms of the protease, is detected in cortical granules by immunoblot analysis.
38                                     Aberrant cortical granule cell proliferation and migration occurr
39 V (CaMKIV) is highly expressed in cerebellar cortical granule cells and deep nuclear neurons in the c
40 s of many species are incompetent to undergo cortical granule (CG) exocytosis upon fertilization.
41 ena of ooplasmic microtubule dynamics (OMD), cortical granule (CG) exocytosis, zona pellucida (ZP) ha
42 a(2+) transients resulted in 39 and 49% mean cortical granule (CG) loss, respectively, while CG exocy
43 luding reduced cortical integrity, defective cortical granule (CG) release upon egg activation, failu
44 equired for normal egg Ca2+ oscillations and cortical granule (CG) secretion.
45 luding ooplasmic microtubule dynamics (OMD), cortical granule (CG) status, and zona pellucida (ZP) ha
46 ugh a chromatin-induced localized release of cortical granules (CG) during maturation is thought to b
47       In activated Xenopus eggs, exocytosing cortical granules (CGs) are surrounded by actin "coats,"
48 actin that surround and compress exocytosing cortical granules (CGs).
49           Zymography assays suggest that the cortical granules contain a single serine protease that
50 ndergo a selective turnover of mRNA encoding cortical granule contents.
51           As constituents of the membrane of cortical granules, cysteine string proteins are also ess
52 ns, such as lower IP(3)R1 function, abnormal cortical granule distribution, and disturbed cytoskeleta
53 thylmaleimide inhibition, we determined that cortical granules do have spare active fusion complexes
54 are functional prior to meiosis, even though cortical granules do not use them.
55 ry) as a fluorescent marker, we characterize cortical granule dynamics at single granule resolution i
56                      Thus, the regulation of cortical granule dynamics at the cortex-plasma membrane
57                                              Cortical granules exocytose after the fusion of egg and
58                     Following fertilization, cortical granules exocytose ovastacin, a metalloendopept
59 al stage, egg activation, including abnormal cortical granule exocytosis (CGE), cytoplasmic segregati
60 3 or GalTase antibodies were able to trigger cortical granule exocytosis and activation of GalTase-ex
61                                 Among these, cortical granule exocytosis and compensatory endocytosis
62  the protease-mediated reactions that follow cortical granule exocytosis and contribute to the block
63  subsequent egg activation events, including cortical granule exocytosis and cytoplasmic segregation.
64 rable yet coordinated functions: to regulate cortical granule exocytosis and to mediate chromosome se
65 e plasma membrane in a manner reminiscent of cortical granule exocytosis as described in other specie
66 n 1e is expressed at the earliest stage that cortical granule exocytosis can be detected in oocytes.
67                               Interestingly, cortical granule exocytosis can be elicited in immature
68 ean that rab3 functions in the regulation of cortical granule exocytosis following vesicle docking.
69 nt regions of the rab3 protein, we find that cortical granule exocytosis is inhibited in eggs injecte
70                         We find that whereas cortical granule exocytosis occurs over a narrow thresho
71 d overexpression of full-length Xenopus csp, cortical granule exocytosis was reduced by approximately
72                                IP(3)-induced cortical granule exocytosis was significantly decreased
73 ecies, binding of sperm to the egg initiates cortical granule exocytosis, an event that contributes t
74               From the calcium dependence of cortical granule exocytosis, and from the exposure time
75 ries of Ca(2+)-dependent events that include cortical granule exocytosis, cell cycle resumption with
76  W-7 followed by insemination does not block cortical granule exocytosis, cell cycle resumption, as a
77 nhibition of Ca2+ release and also inhibited cortical granule exocytosis, cytoplasmic alkalinization,
78 phatase SHP2, had no effect on Ca2+ release, cortical granule exocytosis, DNA synthesis, or cleavage.
79         Some events of egg activation, e.g., cortical granule exocytosis, however, appear more sensit
80 gradation and recruitment of maternal mRNAs; cortical granule exocytosis, however, did not occur norm
81                                    Following cortical granule exocytosis, however, rab3 reassociates
82  its essential activity in cell division and cortical granule exocytosis, in developmentally programm
83  intracellular Ca2+, resume meiosis, undergo cortical granule exocytosis, or ZP2 cleavage to ZP2f.
84 lthough the native J-domain of csp inhibited cortical granule exocytosis, point mutations that interf
85 g activation," resulting in calcium release, cortical granule exocytosis, recruitment of maternal mRN
86  buffers and then examined the effect on the cortical granule exocytosis, recruitment of maternal mRN
87 rane fusion events such as sperm-egg fusion, cortical granule exocytosis, the elevation of phosphatid
88 ession of myosin 1e augments the kinetics of cortical granule exocytosis, whereas tail-derived fragme
89 all subsequent egg activation steps, such as cortical granule exocytosis, which modifies the vitellin
90 cytes, we hypothesize that rab3 functions in cortical granule exocytosis.
91 about 30 sec, or roughly at the same time as cortical granule exocytosis.
92 ith the calcium dependence of sea urchin egg cortical granule exocytosis.
93 l Zp2(Mut) embryos despite fertilization and cortical granule exocytosis.
94 teine string proteins are also essential for cortical granule exocytosis.
95 documents an important role for myosin 1e in cortical granule exocytosis.
96 rm binding, independent of fertilization and cortical granule exocytosis.
97 lar injection of myosin 1e antibody inhibits cortical granule exocytosis.
98 p) in phorbol-12-myristate-13-acetate-evoked cortical granule exocytosis.
99                                            A cortical granule-free domain (CGFD) overlies the metapha
100 rized egg, characterized by an actin cap and cortical granule-free domain (CGFD) overlying the meioti
101                          Finally, the single cortical granule-free domain that normally becomes local
102                         In these instances a cortical granule-free domain was observed over each indi
103 he spindle, dictates the localization of the cortical granule-free domain.
104 ganization is associated with non-exocytosed cortical granules from the earlier egg activation defect
105                                  The role of cortical granules in blocking polyspermy is conserved th
106                                We identified cortical granules in Caenorhabditis elegans and have fou
107    Because of its selective association with cortical granules in eggs and oocytes, we hypothesize th
108           We found that the translocation of cortical granules in in vitro-matured oocytes begins wit
109                                Exocytosis of cortical granules in mouse eggs is required to produce t
110 ex during oocyte maturation and anchoring of cortical granules in the cortex.
111 own, set of vesicles, closely apposed to the cortical granules in the egg cortex.
112        We then observed the translocation of cortical granules in these cells by immunolocalization u
113                                              Cortical granule lectin (CGL) is released by the egg of
114 abbit polyclonal Ab to Xenopus laevis 35-kDa cortical granule lectin (XL35; 68% identity with intelec
115  was unknown, namely, the Xenopus laevis egg cortical granule lectin.
116 th anti-receptor antibody are present in the cortical granules located at the inner face of the plasm
117                        Fluorescently labeled cortical granules, microfilaments, and microtubules were
118                         It was observed that cortical granules migrate to the periphery of the oocyte
119 aments and microtubules in the regulation of cortical granule movement toward the cortex during oocyt
120 gand is not a result of contamination by egg cortical granules, nor is it the mouse homolog of oviduc
121 otease 1 (CGSP1), has been identified in the cortical granules of Strongylocentrotus purpuratus eggs,
122 L receptor-like domains each localize to the cortical granules of unfertilized eggs.
123 r work indicated that csp is associated with cortical granules of Xenopus oocytes.
124                                              Cortical granules, once anchored at the cortex, remained
125 pliced to yield proteins destined for either cortical granules or the vitelline layer.
126 ion envelope at fertilization and changes in cortical granule pH.
127 eolytic cleavage of the gp69/64 protein by a cortical granule protease during fertilization removes 2
128 low-quality oocytes may undergo insufficient cortical granule release and zona-hardening, causing alt
129 distinctly trafficked variants reunite after cortical granule secretion at fertilization.
130            An autocatalytic serine protease, cortical granule serine protease 1 (CGSP1), has been ide
131 ino-acid-residue protein that we refer to as cortical granule serine protease 1 (CGSP1).
132                          Here we show that a cortical granule serine protease of sea urchins is the m
133 ized insulin and reveal that the motility of cortical granules significantly changes over time.
134 This accumulation of csp at sites other than cortical granules suggested that mislocalized csp might
135 P3 are blocked in their ability to exocytose cortical granules, suggesting that the inhibition is dir
136                          We find that native cortical granule targets of the protease are beta-1,3 gl
137 and manganese are sequestered in a system of cortical granules that are abundant at the animal pole.
138 ts in the exocytosis of approximately 15,000 cortical granules that are docked at the plasma membrane
139 is cleavage is associated with exocytosis of cortical granules that are peripherally located subcellu
140                                          (3) Cortical granules that translocate in vitro are capable
141 ng oocytes coincident with the appearance of cortical granules, the vesicle in which the hyalin prote
142  Here we report that rab3 is associated with cortical granules throughout oogenesis, during cortical
143 ory step in the coordinated translocation of cortical granules to the egg cortex.
144 ral of these genes by RNAi, we observed that cortical granule trafficking was disrupted and the eggsh
145 iameter (Lytechinus variegatus), many of the cortical granules translocate upwards of 60 micro m to r
146 ation enables us to examine the mechanism of cortical granule translocation and other processes that
147 ings to discover that meiotic maturation and cortical granule translocation are inseparable.
148                         We also learned that cortical granule translocation requires association with
149                                   Inhibiting cortical granule translocation severely impaired the blo
150                      To study the process of cortical granule translocation to the cell surface we ha
151 rtical granules throughout oogenesis, during cortical granule translocation, and while docked at the
152  very little is known about the mechanism of cortical granule translocation.
153                          Here we investigate cortical granule transport and dynamics in live mammalia
154                           In many organisms, cortical granules undergo exocytosis following fertiliza

 
Page Top