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1 peptides melanocyte-stimulating hormone and corticotropin.
2 FSH)], with adrenocorticomelanotropic cells [corticotropin (ACTH) and alpha-melanotropin (alpha-MSH)]
3 in level and lack of stress- and cue-induced corticotropin and cortisol responses, higher anxiety, an
5 ects of cortisol metabolism: daily levels of corticotropin and cortisol; plasma cortisol clearance, m
6 retion of cortisol suppresses the release of corticotropin by pituitary corticotrophs, which results
8 ticotropin precursor proopiomelanocortin and corticotropin expression were assessed by means of a pol
10 lls: inositol polyphosphate-5-phosphatase A, corticotropin hormone precursor, ribosome biogenesis reg
18 and tumor DNA obtained from 33 patients with corticotropin-independent macronodular adrenal hyperplas
19 A axis dysregulation, marked by higher basal corticotropin level and lack of stress- and cue-induced
23 er in the patients than in controls, whereas corticotropin levels were lower (P<0.001 for both compar
27 d greater neutral, relaxed-state cortisol to corticotropin ratio (adrenal sensitivity) were each pred
29 gh an interaction between the stress hormone corticotropin releasing factor (CRF) and glutamate relea
35 port that the stress-associated neuropeptide corticotropin releasing factor (CRF) produces a profound
36 icotine withdrawal was mediated by increased corticotropin releasing factor (CRF) receptor-1 expressi
42 ontains a large number of neurons expressing corticotropin releasing factor (CRF), a neuropeptide tha
43 until the corticotropes are stimulated with corticotropin releasing factor (CRF), whereupon SSTR2 ex
47 he transmembrane domains of the glucagon and corticotropin releasing factor 1 (CRF1) receptors to dev
49 oupled receptors, which bind peptides of the corticotropin releasing factor family and are key mediat
51 analysis showed significant upregulation of corticotropin releasing factor receptor 2 (CrfR2) in the
53 nvestigated here the interaction between the corticotropin releasing factor receptor type 1 (CRF1R) a
55 fering the neural stress response induced by corticotropin releasing factor, and promoting stress res
56 in stress and appetite regulation, including corticotropin releasing factor, pro-opiomelanocortin B,
57 88-induced c-Fos activation were observed in corticotropin releasing factor-containing neurons of the
58 eus of the hypothalamus and primarily in non-corticotropin releasing factor-containing neurons of the
59 rom the basolateral amygdala (BLA) away from corticotropin releasing factor-expressing (CRF(+)) centr
62 on, and its glutamatergic neurons expressing corticotropin releasing hormone (Bar(Crh/Vglut2)) are im
63 eloped for the detection of the neuropeptide Corticotropin Releasing Hormone (CRH) based on the immob
68 ethylation of the cortisol-regulating genes, corticotropin releasing hormone (CRH; P=0.05) and glucoc
69 icosterone receptors, their regulator Fkbp5, corticotropin releasing hormone and its receptor, oxytoc
70 from the nucleus tractus solitarii (NTS) to corticotropin releasing hormone neurons in the paraventr
71 erone levels), and alleviated by antalarmin (corticotropin releasing hormone receptor 1 antagonist).
72 cluding the membrane progestin receptor, the corticotropin releasing hormone receptor, and the 5HT1a
77 mRNA was found to partially colocalize with corticotropin-releasing factor (CRF) and growth hormone-
83 neurons that release the stress neuropeptide corticotropin-releasing factor (CRF) drive anxiety-like
84 regulation of the central extrahypothalamic corticotropin-releasing factor (CRF) expression is assoc
87 hypersecretion of the stress neuromediator, corticotropin-releasing factor (CRF) has been implicated
88 rofiling of relevant PI cells identified the corticotropin-releasing factor (CRF) homolog, DH44, as a
89 ike ShA cocaine self-administration, reduced corticotropin-releasing factor (CRF) immunodensity in th
90 ed body of work indicates a crucial role for corticotropin-releasing factor (CRF) in neurobiological
91 termined the role of the stress neurohormone corticotropin-releasing factor (CRF) in stress-induced b
92 ed on previous work hypothesizing a role for corticotropin-releasing factor (CRF) in the IC during cr
94 ine was compared following overexpression of corticotropin-releasing factor (CRF) in the NAc of femal
95 literature suggests that catecholamines and corticotropin-releasing factor (CRF) interact in a seria
100 from chronic alcohol exposure contains ~80% corticotropin-releasing factor (CRF) neurons and that th
102 and anxiety and activates a subpopulation of corticotropin-releasing factor (CRF) neurons in the bed
103 cohol intake specifically recruited GABA and corticotropin-releasing factor (CRF) neurons in the mPFC
104 the relationship between corticosterone and corticotropin-releasing factor (CRF) on both beta-amyloi
105 ed the effect of an intravenous injection of corticotropin-releasing factor (CRF) on fructose malabso
106 and the influence of the stress neuropeptide corticotropin-releasing factor (CRF) on these responses.
107 nced fear memory but did not increase either corticotropin-releasing factor (CRF) or corticosterone.
112 duction and Abeta elevation are dependent on corticotropin-releasing factor (CRF) receptor 1 signalin
115 We recently demonstrated that activation of corticotropin-releasing factor (CRF) receptors in the ca
118 induced relapse through alterations in brain corticotropin-releasing factor (CRF) regulation of neuro
121 eviously demonstrated that activation of the corticotropin-releasing factor (CRF) system potentiates
123 f neonatal amygdala (Neo-A) lesions on brain corticotropin-releasing factor (CRF) systems and hypotha
127 clase-activating peptide, PAC1 receptor, and corticotropin-releasing factor (CRF), (CRF1) receptor.
129 nsistent with this, the CEA highly expresses corticotropin-releasing factor (CRF), an important modul
130 (Dh44), a neuropeptide related to vertebrate corticotropin-releasing factor (CRF), and its receptor,
131 to the BNSTDL, is thought to communicate via corticotropin-releasing factor (CRF), but studies have y
133 ological studies indicate the involvement of corticotropin-releasing factor (CRF), noradrenaline, dop
134 es in receptors for the stress neuropeptide, corticotropin-releasing factor (CRF), that render the lo
138 ways expressing the stress-sensitive peptide corticotropin-releasing factor (CRF), which has been ide
139 ral amygdala noradrenergic substrates [via a corticotropin-releasing factor (CRF)-dependent mechanism
140 allenge has been shown previously to cause a corticotropin-releasing factor (CRF)-mediated increase i
142 de transmitter in the brain that counteracts corticotropin-releasing factor (CRF)-mediated stress and
143 und that GluN2D is functionally expressed on corticotropin-releasing factor (CRF)-positive BNST cells
150 This study tested the hypothesis that the corticotropin-releasing factor (CRF1) antagonist GSK5616
151 ist (eticlopride), D2R agonist (quinpirole), corticotropin-releasing factor 1 (CRF1) antagonist (anta
152 t of brain stress neurotransmitters, such as corticotropin-releasing factor and dynorphin, in the neu
153 alcohol drinking by increased expression of corticotropin-releasing factor and its feedback regulati
154 that promote stress and resilience, such as corticotropin-releasing factor and nociceptin, has been
156 cuses on the HPA axis-based interventions of corticotropin-releasing factor antagonists and the gluco
159 ephalin, thyrothropin-releasing hormone, and corticotropin-releasing factor immunoreactive cells in t
162 s in the anterior hypothalamus that may gate corticotropin-releasing factor output from the amygdala
163 ss, the physiological consequence of central corticotropin-releasing factor receptor (CRF-R) activati
164 viously reported differential involvement of corticotropin-releasing factor receptor (CRFR) 1 and 2 i
165 We aimed to characterize the effects of the corticotropin-releasing factor receptor 1 (CRF-R1) antag
166 noradrenergic (NE) receptors (alpha1) via a corticotropin-releasing factor receptor 1 (CRF-R1)-depen
167 rial evaluating the efficacy of GSK561679, a corticotropin-releasing factor receptor 1 (CRF1 receptor
169 Similarly to what has been observed for the corticotropin-releasing factor receptor 1 (CRFR1), SAP97
170 me proliferator-activated receptor gamma and corticotropin-releasing factor receptor 1 were notable e
171 mutants with constitutive activation of the corticotropin-releasing factor receptor family homologue
172 anaphylaxis and psychological stress through corticotropin-releasing factor receptor subtype 1 (CRF(1
173 In this study we investigated the role of corticotropin-releasing factor receptor subtype 2 (CRF(2
174 d, we took the CRF(2(a))R and the homologous corticotropin-releasing factor receptor type 1 (CRF(1)R)
175 esent study investigated whether blockade of corticotropin-releasing factor receptor type 1 (CRF-R1)
176 n reflect reductions in anandamide driven by corticotropin-releasing factor receptor type 1 (CRF1) po
177 we investigated interactions of the class B corticotropin-releasing factor receptor type 1 (CRF1R) w
179 ular membrane compartments, we show that the corticotropin-releasing factor receptor type 1 has a spe
180 ure of the transmembrane domain of the human corticotropin-releasing factor receptor type 1 in comple
183 vation of the central stress response, while corticotropin-releasing factor receptor type 2 (CRFR2) h
185 eviously, we observed abnormal expression of corticotropin-releasing factor receptor type 2 (CRFR2) t
188 n in the BNST is unaffected by alpha1-AR and corticotropin-releasing factor receptor-1 (CRFR(1)) anta
189 Effects on attention were attenuated by the corticotropin-releasing factor receptor-1 antagonist ant
192 alysis studies it has been shown to increase corticotropin-releasing factor release in extrahypothala
194 ry-adrenal axis), (4) the (gastrointestinal) corticotropin-releasing factor system, and (5) the intes
197 icated that repeated social stress decreased corticotropin-releasing factor type 1 receptor and incre
199 disrupts this LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s)
200 disrupts this LTCC-based mechanism; instead, corticotropin-releasing factor type 1 receptors (CRF1s)
202 demonstrated that the mechanism involved the corticotropin-releasing factor type 2 receptor, cAMP ele
203 cial behavior (especially neuropeptide Y and corticotropin-releasing factor) are modulated by alcohol
206 -system recruitment of brain stress systems (corticotropin-releasing factor, dynorphin, norepinephrin
207 tuitary-adrenal axis, including signaling by corticotropin-releasing factor, in the pathophysiology o
208 w stress interacts with the neuromodulators, corticotropin-releasing factor, norepinephrine, dopamine
210 ess effect by counteracting the functions of corticotropin-releasing factor, the primary stress-media
211 peptides (ghrelin, nesfatin-1, somatostatin, corticotropin-releasing factor, thyrotropin-releasing ho
212 rmittent access to palatable food results in corticotropin-releasing factor-1 (CRF1) receptor antagon
215 luding those that encode the stress hormones corticotropin-releasing hormone (CRH) and adrenocorticot
217 n-33 (IL-33), and stress molecules including corticotropin-releasing hormone (CRH) and neurotensin (N
218 larval zebrafish with transgenically labeled corticotropin-releasing hormone (CRH) cells, which repre
219 employed viral-genetic approaches to reduce corticotropin-releasing hormone (Crh) expression in the
220 axis initiates the production and release of corticotropin-releasing hormone (CRH) from the paraventr
221 activity for the suppression of hypothalamic corticotropin-releasing hormone (CRH) gene expression an
222 nstrate that a cluster of neurons expressing corticotropin-releasing hormone (Crh) in the pontine mic
228 tin, thyrotropin-releasing hormone (TRH) and corticotropin-releasing hormone (CRH) neurons expressed
229 synaptic metaplasticity in stress-responsive corticotropin-releasing hormone (CRH) neurons in female
230 affects excitatory and inhibitory inputs to corticotropin-releasing hormone (CRH) neurons in the hyp
231 naptic plasticity at glutamate synapses onto corticotropin-releasing hormone (CRH) neurons in the par
232 tical areas transmit signals to hypothalamic corticotropin-releasing hormone (CRH) neurons, which con
233 augments excitatory synaptic strength in PVN corticotropin-releasing hormone (CRH) neurons, with GLP-
234 el synergistic actions of corticosterone and corticotropin-releasing hormone (CRH) on synaptic physio
235 ing hormone, oxytocin, arginine vasopressin, corticotropin-releasing hormone (CRH) or thyrotropin-rel
236 ress, adrenal corticosterone and hippocampal corticotropin-releasing hormone (CRH) permeate memory-fo
237 g-standing paradigm posits that hypothalamic corticotropin-releasing hormone (CRH) regulates neuroend
240 In addition, increased activation of the corticotropin-releasing hormone (CRH) system within the
241 working memory (WM) deficits; changes to the corticotropin-releasing hormone (CRH) system; and struct
242 rtisol concentrations and gene expression of corticotropin-releasing hormone (CRH) were not affected
243 e production and release of the neuropeptide corticotropin-releasing hormone (CRH) within the hippoca
247 nals were collected and processed to measure corticotropin-releasing hormone (CRH), urocortin (Ucn),
248 activities by stimulating the expression of corticotropin-releasing hormone (CRH), urocortin, proopi
249 multilabeled for vasotocin, mesotocin (MT), corticotropin-releasing hormone (CRH), vasoactive intest
250 ormone 44 (Dh44), a homolog of the mammalian corticotropin-releasing hormone (CRH), were specifically
251 ticoids and the stress-released neuropeptide corticotropin-releasing hormone (CRH), which influence t
252 evious studies have described the effects of corticotropin-releasing hormone (CRH), which is released
253 he adult brain, we have virally traced local corticotropin-releasing hormone (CRH)-expressing inhibit
257 found that the rs28365143 variant within the corticotropin-releasing hormone binding protein (CRHBP)
261 loss-of-function mice, either with global or corticotropin-releasing hormone neuron-specific deletion
264 gated expression of stress-response receptor corticotropin-releasing hormone receptor (CRHR) in bladd
265 e other ligand-binding site defined--for the corticotropin-releasing hormone receptor 1 (CRF1R)--whic
269 51 [FKBP5], glucocorticoid receptor [NR3C1], corticotropin-releasing hormone receptor 1 [CRHR1]) in i
270 elch-like protein 2)), chromosome 17 (CRHR1 (corticotropin-releasing hormone receptor 1) and MAPT (mi
271 7, rs77804065 (p = 1.5 x 10(-12)), at CRHR1 (corticotropin-releasing hormone receptor 1); the protein
272 opeptide urocortin 2 (UCN2) and its receptor corticotropin-releasing hormone receptor 2 (CRHR2) are h
274 5-2 muM) for 6 hours significantly increases corticotropin-releasing hormone receptor-1 (CRHR-1) mRNA
275 found a significant three-way interaction on corticotropin-releasing hormone receptor-1 (Crhr1) gene
276 bellar Purkinje cells, and co-localized with corticotropin-releasing hormone receptors in the latter.
278 in both the initial and replication samples: corticotropin-releasing hormone signaling, cardiac beta-
279 l enrichment analyses revealed enrichment of corticotropin-releasing hormone signaling, GNRH signalin
281 way in rat paraventricular hypothalamic CRH (corticotropin-releasing hormone) neuroendocrine neurons
283 ernal blood (i.e., C-reactive protein (CRP), corticotropin-releasing hormone, and cytokines) were com
284 at several peptide markers (cholecystokinin, corticotropin-releasing hormone, and tachykinin 1) label
285 not GABAergic, and do not express oxytocin, corticotropin-releasing hormone, vasopressin, or prodyno
286 mic activation of the pituitary changes from corticotropin-releasing hormone-dominant to arginine vas
288 f inhibition by dynorphin, somatostatin, and corticotropin-releasing hormone-expressing neurons in th
289 al raphe-originating serotonergic control of corticotropin-releasing hormone-mediated excitation of t
290 refrontal cortex restrains the amygdala, the corticotropin-releasing hormone/hypothalamic-pituitary-a
293 We evaluated adrenal function using short corticotropin stimulation test in 157 episodes of gastro
294 We evaluated adrenal function using short corticotropin stimulation test in patients with cirrhosi
300 ushing's syndrome appears to be regulated by corticotropin, which is produced by a subpopulation of s