ライフサイエンスコーパス: costimulate

1 CD4 T cell TIM-1 signaling costimulates a variety of immune responses in allograft

2 e cortical representations of the two digits costimulated above-resonance shifted closer, potentially

3 A-1, which has been shown previously both to costimulate activated effector CD4(+) and CD8(+) T cells

4 Adoptive transfer of costimulated activated allogeneic T cells is feasible, d

5 In contrast, NKG2D costimulates activated CD8(+) T cells.

6 globin-specific 3.L2 murine T cell hybridoma costimulates activation for IL-2 secretion both with ant

7 Although BLyS costimulates adaptive immune cells, the ability of BLyS

8 of covalently dimeric and wild type B7-1 to costimulate Ag-specific T cell proliferation was also as

9 In contrast, Gal-3 failed to costimulate Ag-specific T cell responses; moreover, it a

10 We found that Gal-1 costimulated Ag-specific T cell responses similarly to G

11 Engagement of NKG2D triggers NK cells and costimulates Ag-specific effector CD8 alphabeta T cells.

12 D86 expressed by NSCs are functional and can costimulate allogeneic cells in a mixed lymphocyte react

13 of a second signal is tied to its ability to costimulate (along with stimulation through the TCR) pro

14 :C)] is a known inducer of IFN-beta but also costimulates an inflammatory response.

15 ns between CD28 and members of the B7 family costimulate and enhance T cell responses, recent evidenc

16 ICAM-1 costimulates anti-CD3-mediated T cell proliferation and

17 t of NKG2D triggers natural killer cells and costimulates antigen-specific effector T cells.

18 sheet, mimicking the two digit regions, were costimulated at different frequencies.

19 rafts followed by ex vivo anti-CD3/anti-CD28 costimulated autologous T cells at day 2 after transplan

20 fusion of in vivo vaccine-primed and ex vivo costimulated autologous T cells followed by post-transpl

21 sm to explain how CD22 and BCR signaling can costimulate B-cell proliferation and induce apoptosis in

22 ule as anti-CD154-conjugated Sepharose beads costimulated B cell responses induced by engaging surfac

23 -stimulated B cells, whereas IL-21 primarily costimulated B cells activated by anti-IgM or anti-IgM p

24 In addition, the HB22.7 MoAb costimulated B-cell proliferation with either anti-IgM,

25 IL-21 costimulates B cell proliferation and cooperatively with

26 the tumor necrosis factor (TNF) family that costimulates B lymphocyte proliferation.

27 elease BAFF at levels sufficient to potently costimulate BCR-induced B-cell proliferation.

28 fore, that B7.2 expressed on T cells may not costimulate but instead inhibit the T cell response by p

29 ich region of the cytoplasmic domain fail to costimulate but serve as effective death inducers.

30 ntracellular domain of FasL is sufficient to costimulate by enhancing the phosphorylation of Akt, ERK

31 n and production of IL-10 by these Tregs was costimulated by activation of glucocorticoid-induced TNF

32 to induce IgE synthesis by purified B cells costimulated by anti-CD40 mAbs.

33 e memory T-cell subsets and Tregs are better costimulated by CD28.

34 ells: Primary human naive T cells are better costimulated by CD81, whereas the memory T-cell subsets

35 enograft model, CD30CAR(+) EBV-CTLs could be costimulated by EBV-infected cells and produce antitumor

36 T cells from long-term HEL-exposed mice are costimulated by Fas ligation.

37 and P2Y G-protein-coupled receptors that are costimulated by nucleotides released during physiologic

38 xpression of CD86 on CVID B cells, even when costimulated by the BCR, or induce production of IL-6 or

39 e- to ninefold greater when the T cells were costimulated by way of the NK receptor.

40 istence after adoptive transfer than do CD28-costimulated CAR (28zeta) T cells.

41 4-1BB-costimulated CAR (BBzeta) T cells exhibit longer persist

42 icited effector functions equivalent to CD28-costimulated CAR T cells and prevented HIV-induced CD4(+

43 In contrast, first-generation and 4-1BB-costimulated CAR T cells increased the occurrence of GVH

44 exceeded 4-1BB-, CD28- and third-generation costimulated CAR T cells, elicited effector functions eq

45 similar to that achieved with CD28- or 4-1BB-costimulated CARs, and heightened persistence was simila

46 te that alloreactive T cells expressing CD28-costimulated CD19 CARs experience enhanced stimulation,

47 Human endothelial cells (EC) costimulate CD4(+) memory T cell activation through CD58

48 and -1beta) from the culture supernatants of costimulated CD4 T cells.

49 -1 has an increased capacity to replicate in costimulated CD4+ T cells compared to X4 HIV-1.

50 cl-xL promoter and induced apoptosis in CD28-costimulated CD4+ T cells.

51 By comparing CD3/CD28-costimulated CD4+ T-cell cultures infected by several X4

52 MAdCAM signaling through alpha(4)beta(7) costimulates CD4(+) T cells and promotes HIV replication

53 Furthermore, B7-H1 preferentially costimulates CD4+ T cells independently of CD28 and enha

54 through the NK high-affinity IL-2 receptor, costimulates CD56(bright) NK cells to secrete IFN-gamma.

55 lasmic domain of Fas ligand is sufficient to costimulate CD8(+) T cells by driving Fas ligand recruit

56 B7 molecules could directly costimulate CD8+ cells, as purified CD8+ cells developed

57 While NKG2D did not costimulate CD8+ T cells on its own, it was able to modi

58 The ability of costimulated CD8 cells to respond to interleukin 16 (IL-

59 optimal CD8 T cell proliferation, 4-1BB also costimulated CD8 T cell proliferation independently of I

60 ing receptor complex that triggers NK cells, costimulates CD8 alpha beta and V(gamma)9V(delta)2 gamma

61 irectly stimulates NK cells and macrophages, costimulates CD8(+) T cells, and plays a substantial rol

62 Therefore, TGF-beta 1 costimulates CD8+ T cell growth via activation of the al

63 Since the B7 molecules could be costimulating CD8+ and/or CD4+ T cells in wild-type anim

64 We hypothesized that sialic acids on the costimulated cell surfaces may contribute to the inhibit

65 was significantly enhanced and sustained in costimulated cells compared with that seen in cells stim

66 In contrast, CD28-costimulated cells that also expressed Fas and Fas ligan

67 anti-TCR Ab-stimulated cells but not in CD28-costimulated cells, suggesting that CHX may also act by

68 he caspase-independent mode of cell death in costimulated cells, these findings suggest the activatio

69 hibits CD28-induced message stabilization in costimulated cells.

70 Taken together, our results reveal that B7H costimulates clonal expansion of, and cognate destructio

71 ntigen-activated B cells can express B7h and costimulate cognate antigen-activated T cells through IC

72 CYT that is specifically unable to bind MKP6 costimulates considerably larger quantities of IL-2 from

73 th in TCR-activated DP thymocytes but do not costimulate DP thymocytes to initiate the differentiatio

74 We found that NKG2D was able to costimulate DUC CTL responses and did so in a manner sim

75 y the natural ligand RAE1epsilon was able to costimulate effector functions of a murine CTL line gene

76 We propose that CD94/NKG2 heterodimers may costimulate effector functions of differentiated Th1 cel

77 NKG2D receptor, which activates NK cells and costimulates effector T cells, are inducibly expressed u

78 n antigen by counter-regulating Tregs and by costimulating effector T cells.

79 ly rescues vascular assembly and motility in costimulated endothelium.

80 Polyclonal peripheral blood CD4+ cells were costimulated ex vivo and subjects were given infusions o

81 T cells were costimulated ex vivo through CD3 and CD28 and expanded f

82 umor-infiltrating donor lymphocytes could be costimulated ex vivo to preferentially activate/expand a

83 ed to express the chimeric receptor and were costimulated ex vivo with beads coated with anti-CD3 and

84 B7-DC costimulates expression of CD40L with faster kinetics th

85 ions, rechallenged cells were preferentially costimulated for IL-2 and IFN-gamma production.

86 tes that exogenous IL-18, which can directly costimulate gammadelta T cells, eliminates the need for

87 and their firing rate was not influenced by costimulated glomeruli.

88 Expression of B7-H1, a costimulating glycoprotein in the B7 family, is normally

89 elated CD4 T cells, suggesting that the dual costimulated helper cells are themselves helped by a CD1

90 ory molecule for T cell activation, and CD46-costimulated human T cells induce a Tr1 Treg phenotype w

91 clear extracts of mitogen- and CD28 receptor-costimulated human T-cells.

92 ably transfected pCD86 in CHO cells modestly costimulates human T cell proliferation and IL-2 secreti

93 Furthermore, engagement of LIGHT costimulates human T cell proliferation, amplifies the N

94 ognized by human CTLA4Ig fusion protein that costimulates human T cells through CD28.

95 The B7-H5/CD28H interaction selectively costimulates human T-cell growth and cytokine production

96 pha 2,3-linked sialic acids from IL-1 + IL-4-costimulated HUVEC by sialidase significantly increased

97 y was to determine whether mesenchymal cells costimulate IELs.

98 g cells inhibits their subsequent ability to costimulate IFN-gamma and IL-4 production from CD4+ T ce

99 d addition of exogenous IL-12 enables ECs to costimulate IFN-gamma at a level comparable to that obse

100 ECs are less effective than PBAMCs at costimulating IFN-gamma production by naive T cells.

101 inding to the 4-1BB receptor and was able to costimulate IL-2 and IFN-gamma release from peripheral T

102 of the CD28 ligand, CD80, on its ability to costimulate IL-2 production by primary T cells.

103 not CHO control transfectants, were able to costimulate IL-4 production.

104 neal macrophages (PEMs) with immobilized mAb costimulated IL-12 production, in contrast to previously

105 TCR-stimulated and CD47-costimulated IL-2 secretion and cell surface CD69 expres

106 We further show that SDF-1 primarily costimulates IL-10 secretion by a diverse population of

107 We report in this study that SDF-1 costimulates IL-10 secretion from T cells containing all

108 an umbilical vein endothelial cells strongly costimulates IL-2 production by human T cells, comparabl

109 hich use both the LFA-3 and B7 molecules, at costimulating IL-2 and IL-4 production.

110 tibodies or recombinant proteins that either costimulate immune cells or block immune inhibitory path

111 nge expression of various cytokines and that costimulate immune effector cells.

112 ast, a nonblocking CD22 MoAb (CD22.5) poorly costimulated in similar experiments.

113 naive and rechallenged 2C-transgenic T cells costimulated in vitro.

114 Thus, T cells are costimulated 'in trans' and sequentially after initial e

115 In particular, B7-DC strongly costimulates interferon gamma but not interleukin (IL)-4

116 IKKss colocalize in the membrane of CD3/CD28-costimulated Jurkat T cells.

117 mice failed to produce IL-12p70 and did not costimulate liver lymphocytes for IFN-gamma production i

118 However, Fas engagement also can costimulate lymphocyte proliferation.

119 stigate the influence of TNF receptor (TNFR)-costimulated lymphocytes on collagen expression in fibro

120 We demonstrated that cFb-IC can costimulate macrophages via dual engagement of TLR-4 and

121 umber of TNF family members whose triggering costimulates maximal proliferation of activated T cells.

122 jor histocompatibility (MHC) class I and II, costimulating molecules and intercellular cell adhesion

123 Both CpG and non-CpG ODNs directly costimulate mouse and human CD4(+) T cells, resulting in

124 CD81 also costimulated mouse T cells that lack CD28, suggesting ei

125 study we have evaluated the role of NKG2D in costimulating mouse and human naive and effector CD8+ T

126 nly transfer of human T cells expressing the costimulated MOv19-BBzeta CAR mediated tumor regression

127 vivo and was only observed in mice receiving costimulated MOv19-BBzeta CAR T cells.

128 sduced to express conventional MOv19-zeta or costimulated MOv19-BBzeta CARs secreted various proinfla

129 ts demonstrate that NKG2D has the ability to costimulate multiple NK activation receptors.

130 ransfectants expressing the OX-2 protein can costimulate murine CD4+ T cells to proliferate in an Ag-

131 gement by ligand or mAb is not sufficient to costimulate naive or effector CD8+ T cell responses in c

132 ty of constitutively active Ras and Raf-1 to costimulate NF-AT activity with a calcium ionophore.

133 d CHO-CD86, in the presence of anti-CD3 mAb, costimulated NFAT-dependent transcriptional activation.

134 hat LPS priming induces IL-12 and IL-15 that costimulate NK cell-derived IFN-gamma.

135 motaxis as culture supernatants derived from costimulated NK cells induced migration of both naive an

136 signaling pathways, we show here that OSCAR costimulates one of the major FcRgamma-associated pathwa

137 act with ligands in the B7 family and either costimulate or co-inhibit signals through antigen-specif

138 They function to costimulate or inhibit BCR signaling through consensus I

139 It has been shown to either costimulate or inhibit T cell responses.

140 show that the PI3K signaling pathway in CD28-costimulated p110delta D910A/D910A T cells is impaired,

141 cytokines produced by activated T cells that costimulate PC differentiation is not clear.

142 tes with activated IKK complexes in CD3/CD28-costimulated primary CD4(+) T cells.

143 abolished PD-1 binding capacity could still costimulate proliferation and cytokine production of T c

144 ule(s) are required for human macrophages to costimulate proliferation of B cells triggered via their

145 uman macrophages generated in vitro strongly costimulate proliferation of dense human tonsillar B cel

146 CD94 mAb did not consistently costimulate proliferation of or IFN-gamma production by

147 B7h can costimulate proliferation of purified T cells through a

148 rrows of Stat5a(-/-) mice, but did stimulate/costimulate proliferation of these cells from Stat5a(+/+

149 T cells via their expressed CD40L, which can costimulate proliferation with CD3 or promote germinal c

150 und that ligands known to directly induce or costimulate proliferation, namely, anti-IgM (anti-Ig), a

151 Additionally, TGF-beta 1-costimulated proliferation correlated with TGF-beta 1 pr

152 In contrast, irradiated K562 cells costimulated proliferation of both CD56(bright) and CD56

153 In addition, SDF-1alpha costimulated proliferation of CD4+ T cells and productio

154 the CD2 molecule by its ligand CD58 clearly costimulated proliferation, cytokine production, and eff

155 ceptors on differentiated Th1 cells in vitro costimulates proliferation and cytokine production with

156 e that engagement of B7-H1 on CD4(+) T cells costimulates proliferation and secretion of IL-10, and s

157 B7-H3 costimulates proliferation of both CD4+ and CD8+ T cells

158 normal donor CD3+ T cells, it significantly costimulates proliferation of CD3+ T cells induced by CD

159 Although B7h costimulated proliferative responses from both CD8(+) po

160 ection model that ectopic B7h expression can costimulate rejection by CD8(+) T cells in the absence o

161 ther a long or a short cyt tail inhibited or costimulated, respectively, TCR/CD3 complex plus CD28 me

162 and B7.2 were comparable in their ability to costimulate responses in T cells previously primed in vi

163 t or Bcl-2 transgenic B cells, IL-21 readily costimulated responses to anti-CD40 while proliferation

164 In these assays, ECs effectively costimulate secretion of IL-2, IFN-gamma, and IL-4 from

165 synergism when mu-thrombin and beta-thrombin costimulate secretion.

166 l TSP1 receptors in T lymphocytes can elicit costimulating signals, in this study we show that intact

167 The use of costimulating SLAM Abs was found to augment the differen

168 Human CD56(dim) NK cells were costimulated specifically by HVEM but not by other recep

169 Using BALMs to costimulate splenic T cells with anti-CD3 as a mitogen s

170 Supernatants of TNF-costimulated SSc lymphocytes induced higher type I colla

171 ytokine responses induced by these different costimulating stages and how they are influenced by host

172 Intimin alpha was found to costimulate submitogenic signals through the T cell rece

173 rties of DCs, providing mechanical cues that costimulate T cell activation.

174 otein T cell Ig and mucin domain (Tim)-1 can costimulate T cell activation.

175 mined the transfectants for their ability to costimulate T cell proliferation in vitro and to induce

176 regression, EL4-B7.2 transfectants failed to costimulate T cell proliferation or induce tumor regress

177 The double transfectant EL4 cells could costimulate T cell proliferation that could be blocked b

178 expressing wild-type CD80, yet are unable to costimulate T cell proliferation.

179 eukin-6 (IL-6) secretion in fibroblasts, and costimulate T cell proliferation.

180 These ligands, however, also costimulate T cell responses.

181 -1 expressed on T cells serves to positively costimulate T cell responses.

182 Here we show that although EL4-B7.1 cells costimulate T cells and induce tumor regression, EL4-B7.

183 CD137-mediated signals costimulate T cells and protect them from activation-ind

184 econdary receptors are up-regulated that can costimulate T cells in concert with TCR engagement.

185 istic Ab or 4-1BB ligand-expressing APCs can costimulate T cells, the physiological significance of 4

186 this pathway can directly and independently costimulate T cells.

187 brane subsequently interacting with gp130 to costimulate T cells.

188 ines can also enhance cell-cell adhesion and costimulate T cells.

189 ands of CCR5, the major coreceptor of HIV-1, costimulate T lymphocyte activation.

190 IFN-gamma-primed lung fibroblasts costimulate T lymphocyte proliferation utilizing CD40, b

191 pecific antigen expression or the ability to costimulate T lymphocytes.

192 However, Fas can also costimulate T-cell activation and promote tumour cell gr

193 These ligands costimulate T-cell receptor (TCR)-mediated signaling.

194 In order to elucidate the parameters which costimulate T-cell-independent antipolysaccharide antibo

195 at multivalent configurations of the aptamer costimulated T cell activation in vitro and mediated tum

196 distinct epitopes on the CD137 glycoprotein costimulated T cell activation irrespective of the engag

197 ICD), we examined whether anergized and CD28-costimulated T cell clones were equally sensitive to Fas

198 hyperproliferation of T cells, and TIM-4-Ig costimulated T cell proliferation mediated by CD3 and CD

199 ed by thrombin cleavage of osteopontin), and costimulated T cell proliferation.

200 FKN expressed on FLS costimulated T cell-activating signals and amplified pro

201 strates that adoptive transfer of autologous costimulated T cells (1) is feasible in heavily pretreat

202 identify a downregulation of miR-150 in CD46-costimulated T cells and identify the glucose transporte

203 -CD3 mAb in the presence of CC-4047 directly costimulated T cells and increased Th1-type cytokines.

204 5 expression and R5 susceptibility to CD3/28 costimulated T cells and some transformed cell lines.

205 ng escalating doses of anti-CD3/CD28 ex vivo costimulated T cells as a therapeutic adjunct for patien

206 antigen-presenting cells bearing chemokines costimulated T cells by a previously unknown two-step co

207 liferation, CTLA-4 engagement prevented ICOS-costimulated T cells from producing IL-4, IL-10, and IL-

208 prominent difference between ICOS- and CD28-costimulated T cells is the quantity of IL-2 produced.

209 transfer of tumor antigen vaccine-primed and costimulated T cells leads to augmented and accelerated

210 CD28/CD3-costimulated T cells produced intracellular IL-2 from al

211 n recall, but even without recall these dual-costimulated T cells respond to signal 3 cytokines such

212 Most importantly, proliferation of TRAIL-R costimulated T cells was strongly impaired, but no apopt

213 nd how signal 3 responses functioned in dual-costimulated T cells we showed that IL-2 induced IL-36R

214 -2 was required for sustained growth of ICOS-costimulated T cells.

215 tes influence IL-2 promoter activity in CD28-costimulated T cells.

216 TNF-costimulated T lymphocytes from SSc patients have a prop

217 e incubated with conditioned media from TNFR-costimulated T lymphocytes, and type I collagen expressi

218 al, but not complete, inhibition of monocyte-costimulated T-cell proliferation-suggesting that both C

219 h is constitutively expressed by T cells and costimulates T cell activation in a CD28-independent man

220 monstrate here that TIM-1 is a molecule that costimulates T cell activation.

221 Thus, CD44H costimulates T cell proliferation by a CD28-independent

222 B7-DC costimulates T cell proliferation more efficiently than

223 Integrin engagement costimulates T cell receptor signaling, but the underlyi

224 d TNF-like cytokine that interacts with DR3, costimulates T cells and augments anti-CD3 plus anti-CD2

225 The TNF family cytokine TL1A (Tnfsf15) costimulates T cells and type 2 innate lymphocytes (ILC2

226 1 is PD-1 independent, indicating that B7-DC costimulates T cells via a second receptor.

227 n (CD47) is a broadly expressed protein that costimulates T cells, facilitates leukocyte migration, a

228 facilitates B lymphocyte differentiation and costimulates T cells.

229 s a recently described B7-like molecule that costimulates T-cell growth and cytokine secretion withou

230 The role of CD28 in costimulating T cell activation is well established.

231 with the functional predominance of B7-1 in costimulating T cell activation when employing APCs from

232 L-deficient dendritic cells are defective in costimulating T cell cytokine production.

233 nt dimeric form of B7-1 is less efficient in costimulating T cell proliferation.

234 oplasmic tail decreased its effectiveness in costimulating T cell proliferative response and early IL

235 and more proinflammatory and were better at costimulating T cells in vitro, compared with the B6 cou

236 uppressive effects of T regulatory cells and costimulating T effector cells.

237 yte reaction, immobilized RELT is capable of costimulating T-cell proliferation in the presence of CD

238 Our data indicate that TNFR2 also costimulates Tconv cells.

239 CD16-activated NK cells costimulate TCR-induced proliferation, and IFN-gamma pro

240 induces cytotoxicity, whereas on T cells it costimulates TCR signaling.

241 CD40 served as effectively as CD28 in costimulating TCR-mediated activation, including inducti

242 ICAM-1 + IL-12-costimulated Th cells were resistant to Fas-mediated cel

243 coinhibit Th2 responses in vitro although it costimulates Th1 responses.

244 2 cytokine production in vitro from CD3/CD28-costimulated Th2 cells.

245 e are numerous additional receptors that can costimulate the activation of T cells.

246 ctor receptor superfamily, has been shown to costimulate the activation of T cells.

247 e showed that wild-type PCBD1 binds HNF1B to costimulate the FXYD2 promoter, the activity of which is

248 the unique role of CD28 signaling is not to costimulate the initial activation of naive T cells, but

249 40R by the OX-40 ligand (OX-40L) is known to costimulate the production of cytokines by activated T l

250 ined the capacity of murine B7-1 and B7-2 to costimulate the production of IL-4 by murine CD4+ T lymp

251 The ability of CD28 to costimulate the production of interleukin-2 (IL-2) expla

252 atients, and that its ligation with collagen costimulated the production of IL-17 by polarized human

253 opulations studied, our data suggest that FL costimulates the expansion of very primitive B cell prog

254 sbp1p binds to spi1p-GTP and costimulates the GTPase-activating protein (GAP)-catalyz

255 ell adhesion, provides survival signals, and costimulates the production of proinflammatory cytokines

256 nisms of this response, we showed that SDF-1 costimulates the transcriptional activities in normal hu

257 lized autoantibodies to B7-H1 are capable of costimulating the proliferation of CD4(+) T cells in vit

258 aising the T cell activation threshold while costimulating the release of proinflammatory cytokines b

259 mber of the TNF family, binds to B cells and costimulates their growth in vitro.

260 lls, after being painted with B7-1, can self-costimulate themselves, elicit enhanced proliferative an

261 t CD56(bright) and CD56(dim) NK cells can be costimulated through different receptors, which may allo

262 PDL1 to inhibit PDL1-PD1 interactions and by costimulating through CD28.

263 In contrast, TLR2 agonist did not costimulate TLR2(-/-)OT-1 or MyD88(-/-)OT-1 T cells.

264 cted to the same stimulation conditions, are costimulated to proliferate by Fas ligation.

265 ticularly of naive phenotype, can instead be costimulated to proliferate by TGF-beta 1.

266 sively with the nonprocessed coactivator and costimulates transcription of an HCF-1-dependent target

267 +) Tconv proliferation, but they only weakly costimulated Treg proliferation and IgG2a production, wh

268 augmented the proliferative capacity of CD28-costimulated Tregs, Foxp3 expression and suppressive fun

269 ld augment the replicative potential of CD28-costimulated Tregs.

270 We tested the feasibility and safety of costimulated, tumor-derived donor lymphocyte (TDL) infus

271 We costimulated two digits on the hand synchronously at, ab

272 rrently with a plasmid DNA vaccine can fully costimulate vaccine-elicited CTL responses.

273 F4 and TNFRSF25 independently and additively costimulate vaccine-induced CD8(+) T cell proliferation

274 The costimulated VEGF production by TGF-beta2 plus thrombin

275 d in vitro through the CD3 epsilon chain and costimulated via the CD28 molecule.

276 NK cells costimulated via the FcR and the IL-12 receptor (IL-12R)

277 CAR-T cells costimulated with 4-1BB or ICOS persist in xenograft mod

278 grin alphaIIbbetaIII activation of platelets costimulated with ADP.

279 granulation was not restored when cells were costimulated with Ag and phorbol ester.

280 iferate spontaneously in vitro and cannot be costimulated with anti-CD28 mAb consistent with a hypera

281 on post-AlloSCT; tumor cell suspensions were costimulated with anti-CD3/anti-CD28 Ab-coated magnetic

282 R greater than that observed with CD8+ cells costimulated with CD3/CD28 antibodies.

283 row Mphi from IFN-gammaR-intact MRL-Fas(lpr) costimulated with CSF-1 or GM-CSF and IFN-gamma was redu

284 oarabinomannan (ManLAM) in mouse macrophages costimulated with gamma interferon (IFN-gamma).

285 However, when IM were costimulated with GM-CSF and IFN-gamma, they expressed a

286 When cells are costimulated with ICAM-1 in the presence of the inhibito

287 s significantly enhanced when the cells were costimulated with IFNgamma.

288 iferation and sprouting of endothelial cells costimulated with IGF-1 and TNFalpha via reduced feedbac

289 his change was antagonized if the cells were costimulated with IL-10.

290 h affinity MIP-1 alpha receptors on NK cells costimulated with IL-12 and IL-15.

291 When NK cells were costimulated with IL-13 and IL-2, IL-13 generally result

292 endent fashion in mouse spleen-cell cultures costimulated with IL-2.

293 A or G, Y = C or T, W = T or A) hot spots if costimulated with T cells and IgM crosslinking, the pres

294 ession was increased further when cells were costimulated with TGF-alpha and cAMP analogs.

295 In contrast, cells costimulated with TLR agonists plus Alum released large

296 e bone marrow-derived dendritic cells (BMDC) costimulated with TLR4 agonists and proapoptotic chemoth

297 cytes were activated with CD3/CD28 beads and costimulated with TNFR-selective variants.

298 eceptors also enhanced Ca(2+) responses when costimulated with type 1 protease activated and M1 musca

299 human monocyte-derived dendritic cells (DCs) costimulated with YGPs and the TLR4 ligand lipopolysacch

300 cid 1 receptors are translated and active in costimulating, with the alpha1-adrenergic receptor, the