ライフサイエンスコーパス: costly

1 validate QTL, but the development of NILs is costly.

2 nstrained, since storing spaced seeds can be costly.

3 available temperature-control platforms are costly.

4 tope-labeled peptides are time-consuming and costly.

5 aluation can be cumbersome, inaccessible and costly.

6 s for HIV detection tend to be laborious and costly.

7 ts for miRNA target site detection are still costly.

8 rmation would presumably also be cognitively costly.

9 ravelers could reduce measles cases, but are costly.

10 iagnostic methods are slow, nonspecific, and costly.

11 isease related miRNAs are time consuming and costly.

12 ion after S. aureus bacteremia is common and costly.

13 However, these devices remain costly.

14 mnography (PSG), but it can be obtrusive and costly.

15 about the current contextual distribution is costly.

16 ety profiles, though PCSK9 inhibitors remain costly.

17 ltiple traits either more beneficial or more costly.

18 rmoregulation is challenging or ecologically costly.

19 tends to require larger sample size which is costly.

20 TI) incidence, though this is burdensome and costly.

21 This differentiation is complex and costly.

22 , and yet such access is often restricted or costly.

23 sociated health consequences are serious and costly.

24 y and fitness, indicating that inbreeding is costly.

25 gulatory testing guidelines is laborious and costly.

26 nostics do not necessarily translate to less costly ACF, as any savings from the test cost can be str

27 ations are learned faster after performing a costly action compared to a less costly action.

28 erforming a costly action compared to a less costly action.

29 ncorporate a hidden surcharge to cover their costly administrative burden.

30 ia living in care homes have distressing and costly agitation symptoms.

31 uge for recessive male-beneficial but female-costly alleles.

32 he distress of self and others to real-world costly altruism, (2) reinforce distinctions between empa

33 in efficiency removes the need for bulky and costly amplified laser sources, and creates the potentia

34 y has made their manufacture complicated and costly and also impeded applications in batteries.

35 quence of food allergies makes managing them costly and anxiety-inducing.

36 for the widely held view that acclimation is costly and are important for investigating evolutionary

37 ity and binding assays are useful but can be costly and are often limited by the kinases that are ava

38 use repeated data collections are considered costly and burdensome.

39 emical method eliminates the need for bulky, costly and complex optical instrumentation that require

40 Bisulfite Sanger sequencing is not only costly and cumbersome to perform, it is inaccurate becau

41 Bipolar Disorder is costly and debilitating, and many treatments have side e

42 , fumonisin determination is performed using costly and demanding chromatography techniques or immuno

43 ed for acute myocardial infarction (AMI) are costly and difficult to predict.

44 ical conjecture that germline maintenance is costly and directly trades off with somatic maintenance.

45 tional care interventions examined were more costly and effective than standard care, with NHVs domin

46 no acids, (15)N-labeled amino acids are less costly and enable direct characterization of nitrogen me

47 s have traditionally relied predominantly on costly and energy-intensive heat-driven procedures such

48 s high-throughput wet-lab settings are often costly and face various challenges, computational approa

49 vision loss resulting from diabetes but are costly and highly underused.

50 Acquisition of resources can be costly and individuals are predicted to optimize foragin

51 pment of lymphoproliferative tumors (LTs) is costly and inefficient.

52 mproves diagnostic sensitivity, it remains a costly and invasive approach.

53 thesia and arthroscopic capsular release are costly and invasive treatments for frozen shoulder, but

54 communities, this calculation is especially costly and involves solving a linear constrained optimiz

55 n acute confusional state that is common and costly and is associated with significant functional dec

56 ch as viral transduction, is one of the most costly and labor-intensive steps in the production of ce

57 er, conventional methods determining TPC are costly and labor-intensive, which are not practical for

58 comparable to biomarkers that are both more costly and less feasible than this approach.

59 Since excessive stiffness is energetically costly and limits the flexibility of responses to pertur

60 s) and causes cognitive impairments that are costly and long lasting.

61 AAV-delivered F8 transgene in an episome are costly and nonpermanent.

62 NA-seq data, where labels for cell types are costly and often impossible to acquire.

63 k preexposure rabies vaccination schedule is costly and often not practicable.

64 is confirmed with tissue sampling, which is costly and only available after tumor resection or biops

65 is (LL)-like lymphoma is a low-incidence yet costly and poorly understood disease of domestic chicken

66 overy in some patients without need for this costly and potentially dangerous technique.

67 decrease societal B consumption and to avoid costly and potentially environmentally harmful CFI incin

68 ve results, and provides strategies to avoid costly and potentially fatal misdiagnoses.

69 However, this approach is computationally costly and propagates any errors in imputation to produc

70 DNA "parts" in large quantities represents a costly and rate-limiting prerequisite for high throughpu

71 option for DME, although the injections are costly and require frequent visits, which increases the

72 efficacy, CTs, especially phase III CTs, are costly and require rigorous planning to optimize the val

73 ve as alternatives to antibiotics, which are costly and risk spread of antibiotic resistance.

74 This approach - although necessary - is costly and slow-moving, making identification of putativ

75 Surveillance for invading insect pests is costly and the trapper usually finds the traps empty of

76 the patterning steps can become economically costly and time consuming.

77 lity problems, as they are labour intensive, costly and time consuming.

78 human-participant surveys, which are usually costly and time consuming.

79 r surgical margins are free of tumor cells-a costly and time- and labor-intensive procedure.

80 However, current fabrication methods are costly and time-consuming and have a small active area w

81 control dataset and (iv) remove the need for costly and time-consuming control experiments.

82 eriments and a mechanistic theory to improve costly and time-consuming empirical methods of optimizat

83 be synthesized in single-phase form, sparing costly and time-consuming synthesis efforts.

84 This compares favorably with other more costly and time-consuming techniques and is over 20 time

85 Cholecystectomy-related claims are costly and time-consuming.

86 al experiments for identifying PPI sites are costly and time-consuming.

87 In addition, the preparation of data is a costly and time-intensive process, the results of which

88 Though sediment monitoring is often costly and time-intensive, modeling its toxicity to biot

89 toring strategies for heavy metals are often costly and unpractical.

90 sease (MAC-PD) can be chronic, debilitating, costly, and associated with a high mortality.

91 CKD is common, costly, and associated with adverse health outcomes.

92 hese have limited multiplexing capacity, are costly, and can exhibit cross-reactivity.

93 IBD is complex and costly, and its increasing prevalence places a greater s

94 cation procedures, which are time consuming, costly, and labor intensive.

95 ance liquid chromatography, are complicated, costly, and labor-intensive, and alternative techniques

96 utilizing radioisotopes are time consuming, costly, and limit discovery to a small group of scientis

97 Yet, carrying a plasmid can be costly, and long-term association of plasmids with their

98 experimental techniques are generally quite costly, and purely computational methods have been unrel

99 rent treatments can be marginally effective, costly, and some have adverse effects.

100 lier, longer calling bouts are energetically costly, and therefore limited by overnight energy expend

101 Apart from being invasive, costly, and time-consuming, this method can suffer from

102 ions, and ecosystem services is challenging, costly, and time-consuming.

103 While costly animal models fail to predict human clinical outc

104 ird-line ART can appropriately allocate more costly antiretrovirals to those with greater levels of H

105 behavior education, barrier methods, and the costly antiviral drug treatments, eliminating or at leas

106 ass-limited sample of interest, which can be costly as mass-limited samples come in many shapes and s

107 technologies are often limited by logistics, costly assays and regular maintenance.

108 and chemotaxis, one of the most complex and costly bacterial behaviors, as a function of bacterial g

109 o fucose, which is metabolized in a proteome-costly bacterial microcompartment that spatially constra

110 ight population at the right time has been a costly barrier to disease control and prevention.

111 res harmful doses to achieve efficacy and is costly because of BMPs' complex synthesis.

112 od transfer, instead of keeping the food, is costly, because it reduces the caloric intake of the ben

113 ltural driver and lead to the maintenance of costly behaviors by both individuals and groups.

114 p formation might involve escalating to more costly behaviors.

115 ad during bioinformatic analyses, preventing costly bioinformatic mistakes, and promoting computation

116 A surrogate model is an approximation to a costly black-box function that can be used for more effi

117 Mastitis in dairy cattle is extremely costly both in economic and welfare terms and is one of

118 t early stress may prompt the development of costly but adaptive strategies that promote survival and

119 sion of new, individualized, and potentially costly cardiovascular therapies.

120 jor depressive disorder is a significant and costly cause of global disability.

121 Protein synthesis is an energetically costly cellular activity.

122 is characterized by extensive, energetically-costly changes across numerous physiological systems.

123 where consumers must cope with energetically costly changes in CO(2) -driven carbonate chemistry that

124 he use of electricity replaces hazardous and costly chemical oxidants.

125 ovel therapeutics to alleviate the impact of costly, chronic diseases such as obesity and substance u

126 error-prone complex process that requires a costly cleanroom facility.

127 community selection is predicted to improve costly community function, and may even force species to

128 Infection is the most common and costly complication of surgery.

129 The top 6 most costly complications were postoperative septic shock (4.

130 nce, which may originate trade-offs on other costly components such as reproduction or immunity.

131 Effective use of these costly control strategies relies on rapid and accurate i

132 m hot acidic metallurgical streams, avoiding costly cooling down.

133 tional biomaterials, and yet the tedious and costly covalent peptide modification and the lack of fac

134 why mutualism is favorable despite seemingly costly cross-feeding metabolites and demonstrated simila

135 proved form of pre-exposure prophylaxis is a costly daily pill, and it is recognized that several opt

136 e unstable heterocyclic chlorides and limits costly decomposition.

137 Sepsis is the most common and costly diagnosis in U.S.' hospitals.

138 Mastitis is one of the most prevalent and costly diseases in dairy cattle.

139 use disorder is a chronic, debilitating, and costly disorder that has increased in prevalence in many

140 on of unwanted SCT leads to the need for its costly disposal or burning at the boiler plant.

141 one that would bypass the time-consuming and costly drug-discovery process.

142 igher perceived facial attractiveness may be costly due to increased oxidative damage in the postmeno

143 Unfortunately, this regimen is costly due to the expense of producing recombinant FVIII

144 Sperm competition favors large, costly ejaculates, and theory predicts the evolution of

145 trolyte, which is currently prepared using a costly electrolysis method with limited productivity.

146 wards the North Pacific, may only be half as costly, energetically, than high-arctic residency or mig

147 ject to artefacts or involve specialised and costly equipment.

148 g the flows of energy and nutrients, reduces costly errors and exploits more opportunities.

149 sential nutrients, and more efficient use of costly exoenzymes.

150 ess, which needs multiple time-consuming and costly experimental steps, has a high attrition rate.

151 Hence, labor-intensive and thus costly experimental studies could be replaced by simulat

152 libraries that enhances the utility of these costly experiments, and may be applicable to the targete

153 gress by reducing the need for extensive and costly experiments.

154 hat could only otherwise be obtained through costly field studies or sophisticated analysis.

155 al adaptation is widely thought to result in costly fitness trade-offs that result in maladaptation t

156 Patients will benefit from less costly follow-up, less anxiety related to these simple c

157 s mungo, in which intergroup fights are more costly for males than females.

158 xidase I (COI) 'barcode' gene, which remains costly for purposes of screening large numbers of unknow

159 tion sequencing (NGS) is still prohibitively costly for routine use in generalized HIV epidemics in l

160 disease, where missteps are potentially very costly given the long-time frames and high expenses of d

161 s have limited access to the currently used, costly HBV assays, which are performed in centralized cl

162 obesity epidemic is developing into the most costly health problem facing the world.

163 vely retained by a community that engages in costly HGT.

164 bypasses the typically labour-intensive and costly histological staining procedures, and could be us

165 in resource allocation between energetically costly immunity and competing processes such as reproduc

166 e well established, but they often depend on costly immunoaffinity sample clean-up.

167 ternal power source and can be prohibitively costly in resource-limited settings and Science, technol

168 ur work shows how plastic responses that are costly in the short term, yet adaptive in the long term,

169 This reduces the need for time consuming and costly in-vivo or in-vitro trials.

170 However, monomer recovery is often costly, incompatible with complex mixtures and energy-in

171 ures are becoming an increasingly common and costly injury in the United States.

172 f the current procedures require complex and costly instrumental configurations, we have developed a

173 To date, however, antioxidant assays require costly instrumentations, laboratory setups, and reagents

174 pecifics from heterospecifics can help avoid costly interactions between closely related sympatric sp

175 Costly interactions between species that arise as a by-p

176 Hostility towards outgroups contributes to costly intergroup conflict.

177 turbances in the production line would avoid costly interventions related to metabolically inactive m

178 nship discord and dissolution are common and costly, interventions are needed to treat distressed cou

179 grilus planipennis), the United States' most costly invasive forest insect to date, within the pan-ge

180 Implementation of EUHC would require costly investment, especially in LICs.

181 ns of health and conservation concern before costly investments in vaccine design and testing.

182 xic, flammable organic electrolytes or often costly ionic liquids.

183 But just how costly is inbreeding in small populations?

184 ing a steady head necessitates energetically costly kinematics.

185 To reduce prolonged and costly laboratory experiments, recent advances in comput

186 enes, to microbes, to complex organisms with costly learning (Baldwin effect) or maintained cooperati

187 ent paradigms for drug safety evaluation are costly, lengthy, conservative, and impede efficient drug

188 ng any additional external redox reagent and costly ligand system.

189 operate, need large reagent volumes, and are costly, limiting their usability.

190 erefore require relatively high coverages of costly long-read data to produce high-quality assemblies

191 techniques are typically time-consuming and costly, making them inefficient for early diagnosis of i

192 These findings highlight how costly measles outbreaks can be, the value of this infor

193 nctionality in structures without dispersing costly mechanophores in the bulk is demonstrated by usin

194 of the financial and health consequences of costly medical interventions.

195 Eating disorders are disabling, deadly, and costly mental disorders that considerably impair physica

196 idea of replacing the all-too-often rare and costly metals from catalysis has motivated efforts to de

197 amples as it's a less destructive and a less costly method compared to DNA and protein based conventi

198 f these principles to help avoid potentially costly mistakes in both basic and translational research

199 Compact, less costly, monochromatic X-ray sources based on very high f

200 ly regulated, reflecting a trade-off between costly motor actions and perceived threat level.

201 he eye, potentially replacing protracted and costly multidisciplinary assessments and allowing for fa

202 Cancer, in particular, with its costly, multidisciplinary care, poses considerable finan

203 arly animals, sodium is essential to running costly Na-K ATPases.

204 The invasive and costly nature of this procedure severely limits its appl

205 to pre-calculate a rigid and computationally costly neural feedback control solution.

206 Less disruptive and costly NPIs can be as effective as more intrusive, drast

207 ted ecosystems, causing rapid, expansive and costly nutrient-driven instabilities over vast areas of

208 consequences of a decision are sufficiently costly, obligation motivates the actor to forgo potentia

209 Asthma ranks among the most costly of chronic diseases, accounting for over $50 bill

210 young age and reducing the need for multiple costly, often invasive tests.

211 linical superiority of expensive versus less costly options, substantial opportunity exists to improv

212 Previously reported systems require costly or bespoke materials not available in most countr

213 when obtaining such consent is prohibitively costly or burdensome, as long as mechanisms are in place

214 um specimen, and traditional diagnostics are costly or unavailable.

215 y from the reads is either not feasible, too costly, or unnecessary.

216 ffects on hosts, leaving hosts vulnerable to costly partnerships.

217 onsequent low back pain (LBP) are common and costly pathological processes that require improved trea

218 ks reduce the risks during disruptions, more costly plants must provide alternative supplies.

219 ws the quick acceleration of the adoption of costly policies across countries beginning in mid-March

220 me by excluding relevant but computationally costly predictive inputs.

221 ssistance programs improve patient access to costly prescription drugs, recent federal investigations

222 ation using low-temperature steam in lieu of costly pressure or temperature swings.

223 tridioides difficile infection (HO-CDI) is a costly problem leading to readmissions, morbidity and mo

224 he 2-y rodent bioassay, a time-consuming and costly procedure.

225 ecialist handling or involve complicated and costly procedures.

226 Drug Discovery is a lengthy and costly process and has faced a period of declining produ

227 viduals are willing and able to go about the costly process of questioning them and exploring other v

228 due to long thermal soak, loading time, and costly process.

229 Costly proprietary panoramic multielectrode (64-256) acq

230 a is one of the most common, burdensome, and costly psychiatric disorders in adults worldwide.

231 eir environment, involving the production of costly public goods that can be exploited by neighbourin

232 Childhood conduct problems are a costly public health problem and are five times more com

233 While costly punishment (Helbing et al. in New J Phys 12:08300

234 escent markers, which necessitate the use of costly reagents and time-consuming labeling procedures.

235 in adults who had engaged in extraordinarily costly real-world altruism: donating a kidney to a stran

236 Because of this potentially costly sacrificial process, we investigated if ubiquitin

237 mechanism for these anomalies in 2017 (most costly season on record) compared to the recent active 2

238 arkably reduces the need for computationally costly sequence alignment.

239 Left-handedness is a costly, sexually dimorphic trait found at low frequencie

240 entirely avoids the slow and computationally costly signal processing and feature extraction steps by

241 Costly signaling theory was developed in both economics

242 ee, can be made more informative by applying costly signaling via the virtual physics of rating devic

243 lection, reciprocity, learning-to-mother and costly signalling hypotheses explain non-parental childc

244 ing requirement for anesthesia or restraint, costly software/hardware, or fluorescently-labeled anima

245 also are more likely to have longer and more costly stays.

246 stem is a crucial, and often computationally costly, step in understanding its thermodynamics.

247 and use of quarantine centres was the least costly strategy, and no other strategies were cost-effec

248 maging equipment, bladder catheterization or costly surgical equipment.

249 These costly techniques have focused on damaging adipocyte cel

250 Social pressure to adopt costly technology, in our case on-site sewage treatment,

251 using more sensitive and specific, yet more costly, tests such as Xpert MTB/RIF in ACF in a high-bur

252 flucytosine (5FC) was as effective and less costly than 2 weeks of amphotericin-based regimens.

253 Non-invasive ventilation is more complex and costly than continuous positive airway pressure but migh

254 MEK generated greater utilities and was less costly than DSAEK.

255 gFOBT was less effective and more costly than FIT.

256 DOT was slightly more effective and costly than GT, with an ICER > $100 000/QALY, compared t

257 Dalbavancin was more costly than SoC for the treatment of ABSSSI, with a high

258 ric walking patterns were less metabolically costly than symmetric walking patterns When one leg was

259 s to care and the frequent unavailability of costly therapies such as dialysis and transplantation.

260 upcoming potentially impactful but sometimes costly therapies.

261 such as surveys and interviews, are usually costly, time consuming and do not scale.

262 Conventional diagnostic practices are costly, time consuming and they lack adequate sensitivit

263 However, immunoadsorption is costly, time consuming, and carries potential risks.

264 through off-line laboratory analysis can be costly, time consuming, and require specialist skills.

265 , traditional methods of soil testing can be costly, time-consuming and are often impractical in rura

266 imental-based repurposing screens, which are costly, time-consuming, and imprecise.

267 ochromator (SM) CPL spectrometers, which are costly to acquire and maintain, and typically require te

268 analyzer(R) and TapeStation(R) products, are costly to acquire and use; they also provide limited inf

269 g and heavy to be transported easily and too costly to be purchased by every health clinic, so fundus

270 ng for a pair of RNAs is O(N6), which is too costly to be used for large-scale analysis.

271 However, such explicit features are usually costly to extract, and typically have limited coverage o

272 tative marker of high biological fitness, is costly to maintain throughout a lifetime and may cause h

273 by secondary intention can be difficult and costly to manage and are profoundly under researched.

274 where they can be ecologically damaging and costly to manage.

275 used a recombinant VEGF, which is extremely costly to manufacture and biologically unstable as well

276 ommon in patients receiving hemodialysis and costly to Medicare.

277 iated with serious adverse outcomes that are costly to patients and society.

278 However, Hi-C experiments are costly to perform and involve multiple complex experimen

279 llision risk from this orbital congestion is costly to satellite operators.

280 restricted to environments, which may be too costly to support under future climate scenarios.

281 However, guide RNA libraries are costly to synthesize, and their limited diversity compro

282 Unplanned hospital revisits are costly to the health care system and associated with los

283 lts in worse outcomes for the patient and is costly to the health service.

284 Sepsis remains common, costly to treat, and presages significant mortality for

285 T2D and its complications are costly to treat, causing considerable morbidity and earl

286 ion of carboxylic acids and/or employment of costly transition-metal photocatalysts.

287 a significant economic burden, mostly due to costly treatment with immunoglobulin.

288 rning to avoid harmful consequences can be a costly trial-and-error process.

289 ccal disease threatens to undermine the most costly vaccination programme currently undertaken.

290 eral desensitization regimens require use of costly venom extracts and require frequent visits over e

291 ulate enzyme functions to treat disease is a costly venture.

292 Annual ryegrass is one of the most serious, costly weeds of winter cropping systems in Australia.

293 top-down gives precise structures but it is costly, whereas bottom-up assembly methods are found by

294 ent education, however published methods are costly which limits their translation into clinical prac

295 , such experiments can be time-consuming and costly, which has led to the development of programmes f

296 ain reaction (RT-PCR) tests are accurate but costly, which makes the regular testing of every individ

297 Although costly, widespread testing and treatment in prisons is c

298 nce factor expression is truly energetically costly within host tissues and whether expression is suf

299 Many such movements are energetically costly yet there is little consensus on whether or how s

300 adding redundant edges to supply networks is costly, yet beneficial for resilience.