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2 ) proteins were individually responsible for counteracting 53BP1-RIF1-Shieldin activity and promoting
3 8-oxoG position dependent, importantly, OGG1 counteracting 8-oxoG outside consensus motif had a profo
4 uce infection in Bombus populations, thereby counteracting a possible contributor to pollinator decli
6 RPS23RG1 regulates synaptic plasticity, thus counteracting Abeta oligomer (oAbeta)-induced cognitive
8 f the aforementioned inhibitory effect and a counteracting accelerated transformation of the contamin
9 y, these results demonstrate that PR-DUB, by counteracting accumulation of H2AK119ub1, maintains chro
11 chromatin plasticity that is mediated by the counteracting activity of histone-methyltransferases and
12 hypothesis: developmental constraints and a counteracting adaptive growth plasticity work in opposit
14 we examined the efficacy of resveratrol for counteracting age-related memory and mood impairments an
15 s the lifespan of flies, worms, and yeast by counteracting age-related oxidation of H2O2-scavenging p
16 eradication of intracellular pathogens, and counteracting aging through clearance of senescent prote
18 ohesin rings around the sister chromatids by counteracting an activity associated with one of cohesin
19 o facilitate replication fork progression by counteracting an as yet ill-defined cohesion "antiestabl
20 ining hippocampal neurogenesis as well as of counteracting an hostile brain microenvironment so to pr
21 We now show that these mutations work by counteracting an increase in the cellular levels of reac
23 ork is emerging as an important strategy for counteracting and repurposing the posttranslational modi
24 g of SecY, reported previously, we observe a counteracting, and ATP-dependent, constriction of SecA a
25 on transport Complex I, oxidative stress and counteracting antioxidant programs were induced in pulmo
26 e leukemia virus (MLV) has a unique means of counteracting APOBEC3 and other cytosolic sensors of vir
27 WT and not APOBEC3 KO mice, indicating that counteracting APOBEC3 is the major function of glyco-Gag
29 erating the reduction of Ni(II) to Ni(0) and counteracting autoinhibition of reduction at Zn(0) by Zn
32 y, treatment of ACAD9 patients should aim at counteracting both CI and fatty acid oxidation dysfuncti
33 em cells, demonstrating the role of BRAVO in counteracting Brassinosteroid (BR)-mediated cell divisio
35 es angiogenesis through a novel mechanism by counteracting c-Myc and transcriptionally repressing vas
36 may help to more precisely assign therapies counteracting cancer cell proliferation and metastatic s
38 gest that IL-6 serves as an extrinsic factor counteracting CD4(+) T-cell-mediated immunity against tu
39 eptum formation in F. graminearum, likely by counteracting Cdk phosphorylation, and is required for p
40 gnancies particularly acquired resistance by counteracting cell death, an effect that can be minimize
41 targeting the GPCR/G protein interfaces and counteracting cellular dysfunctions via focused tuning o
42 ropose that FANCJ plays an essential role in counteracting chromatin compaction associated with unsch
43 atients suggests that it might contribute to counteracting chronic inflammatory processes during HIV
44 eceptors, DF2726A, and showed its effects in counteracting CINP pathways, extending the relevance of
46 eostasis by regulating the expression of key counteracting components of the DNA methylation machiner
49 entified nucleophosmin (NPM) as a key factor counteracting death stimuli in human hepatocellular carc
54 s anti-inflammatory PPAR-alpha activities in counteracting dietary-induced liver fibrosis, we used a
55 not only for anabolic functions but also for counteracting different types of environmental stress, s
56 antioxidant compounds was not successful in counteracting disease initiation and progression in clin
57 tions in 20% (vs 60%) Incongruent blocks for counteracting distraction and conflict, including in the
61 P was applied to the biochar amended soil, a counteracting effect was observed, since the N(2)O mitig
64 identified pathogenic variants operate with counteracting effects on MAPK1 function by differentiall
67 ha and Stx2a by increasing production of the counteracting eicosanoids prostaglandin I2, E1, E2, and
68 ecent atmospheric Hg levels in Central Asia, counteracting emission reductions due to control measure
69 converting glutamine into glutamate, and the counteracting enzyme glutamine synthetase (GS) cause dis
73 homologous recombination repair (HR), while counteracting error-prone non-homologous end joining of
76 one activates PR-A, inducing invasiveness by counteracting estrogen's effects, particularly when cell
78 f genetic diversity during domestication and counteracting factors, a discussion of the relationship
80 gi network and post-Golgi compartments, thus counteracting fluctuations in the sphingolipid biosynthe
81 he vitelline envelope provides controllable, counteracting forces that shape gastrulation movements i
82 s that nutrients and herbivores can serve as counteracting forces to control local plant diversity th
85 elicase promotes DNA replication in trans by counteracting fork stalling on replication barriers, suc
87 while IpaH9.8 helps bacterial propagation by counteracting GBP-dependent cell-autonomous immunity.
89 ed base excision repair is a major mechanism counteracting genomic mutagenesis by A3B, and blocking U
90 ng refers to a range of proposed methods for counteracting global warming by artificially reducing su
91 lycolysis in leukemia cells, as a target for counteracting glucose-dependent survival induced by BCR-
92 , which were suggested to be responsible for counteracting glutamate toxicity in neuronal human-deriv
93 KB directly phosphorylates MYC at serine 67, counteracting GSK3beta-directed threonine 58 phosphoryla
94 however, it is unclear which of the several counteracting H2A deubiquitinases functions along with P
98 and phosphorylates histone H3 at interphase, counteracting histone H3 lysine 9 dimethylation and gene
100 luenza NS1 protein is the main viral protein counteracting host innate immune responses, allowing the
104 e enhanced droughts in southern Europe while counteracting increased precipitation in northern Europe
105 sent us with group-level selection pressures counteracting individual-level ones, need not produce be
111 aging of neural activity we characterize the counteracting interneurons AVK and DVA that utilize FLP-
113 Pp1-87B phosphatase dephosphorylates moesin, counteracting its activation by the Ste20-like kinase Sl
116 TP production could improve immune function, counteracting LA suppressive effects in the immunosuppre
118 jor component of the cornea, yet its role in counteracting live bacteria in the cornea remains poorly
122 suggesting that lake warming may already be counteracting management efforts to ameliorate eutrophic
126 logy is regulated by the balance between two counteracting mitochondrial processes of fusion and fiss
127 ing strength and dynamics, suggesting a dual counteracting modulatory role of SHOC2 in the control of
129 via G(q/11) is necessary and sufficient for counteracting MOR-mediated inhibition of neuronal firing
130 malian cells, maintains cell homoeostasis by counteracting most of the kinase-driven intracellular si
132 e was important for cell-fate regulation, as counteracting MYC repression reduced cell-cycle arrest a
133 ion and survival of primary human B cells by counteracting MYC-induced apoptosis and by inhibiting RB
135 ecretion system (T3SS) and induces functions counteracting neutrophil-induced ion deprivation, radica
136 ynamics mitigate errors in working memory by counteracting noise and integrating contextual informati
139 rior to moderate-intensity training (MIT) in counteracting obesity-induced impairment of left ventric
143 These coordinated events can include toxins counteracting or amplifying effects of another toxin or
144 iated with procognitive effects in humans by counteracting overactivation of the adenosine A2A recept
145 o[4,3-d]pyrimidin-7-amides were effective in counteracting oxaliplatin-induced apoptosis in rat astro
147 ive roles of elevated ketones and lactate in counteracting oxidative stress and as a fuel source for
150 unities and challenges in the field, such as counteracting PARP inhibitor resistance during cancer th
151 oparticle binding to the cell, especially by counteracting part of the hydrodynamic forces of the blo
152 hat novel pharmacological approaches require counteracting pharmacoresistance to improve therapeutic
155 r cell cycle regulator Cdk together with its counteracting phosphatase and that it is executed by con
156 activity, together with upregulation of its counteracting phosphatase Cdc14, controls each of the se
157 phosphorylation during mitosis, identify the counteracting phosphatase complex that restores the pote
158 ng Xenopus laevis egg extracts that the Cdk1-counteracting phosphatase PP2A-B55 functions as a bistab
161 light conditions and metabolic demands, but counteracting phosphatase(s) remain unknown in C. reinha
162 e kinetochore protein KNL1 recruits Aurora B-counteracting phosphatases and the Aurora B-targeting fa
163 Our results support a model in which Cdk-counteracting phosphatases contribute to cell-cycle orde
164 l changes in the distribution of kinases and counteracting phosphatases finely tune the activity of c
165 t kinases (CDKs) is well documented, but the counteracting phosphatases have not been identified yet.
166 DK1 activity relieves inhibition of the CDK1-counteracting phosphatases PP1 and PP2A-B55, allowing wi
168 nt kinase)-antagonising phosphatase Cdc14 by counteracting phosphorylation of the nucleolar protein N
169 increased motivation to eat, a more profound counteracting physiologic stimulus inhibiting increases
170 We conclude that GBS Sia has dual roles in counteracting platelet antimicrobial immunity: conferrin
174 C/C(CDC20) is regulated by CDK1-cyclin B and counteracting PP1 and PP2A family phosphatases through m
175 on Lys4 (H3K4), as a pRB-interacting protein counteracting pRB's role in promoting differentiation.
177 ntly, activity of the right SFG mediates the counteracting processes of inhibitory control and motor
179 eriodic activation and inactivation of a CDK-counteracting protein phosphatase 2A with a B55delta sub
180 alance between cellular repressors and virus-counteracting proteins determines whether or not a cell
184 utoimmune disease observed in females, and a counteracting reduction in diseases such as cancer that
185 y role in maintaining active replication and counteracting replication stress by regulating the repli
187 ly large portion of their coding capacity to counteracting restriction factors by encoding accessory
190 binding with TaSnRK1alpha, demonstrating the counteracting roles of orphan proteins of both host and
191 tion, depending on either the synergistic or counteracting roles of wavefront distortion and birefrin
193 its targets and timing and of the benefit of counteracting self-generated sensory input.SIGNIFICANCE
195 g drugs is thought to be the upregulation of counteracting signalling cascades as a direct response t
197 istent with the patient's wishes and values, counteracting surrogates' helplessness and ending the un
198 hat NRP proteins regulate gene expression by counteracting SWR1, thereby preventing excessive accumul
199 sidered as a possible therapeutic target for counteracting synaptic impairments in the neuronal netwo
201 ize evolution in eukaryotes whereby DNA loss counteracting TE expansion is a major determinant of gen
203 a basis for future allergen immunotherapies counteracting Th2 immune responses on a molecular basis.
205 e that HDAC3 regulates cyclin A stability by counteracting the action of the acetylases PCAF/GCN5.
206 demonstrate that USP30 prevents pexophagy by counteracting the action of the peroxisomal E3 ubiquitin
208 PP2A(Cdc55) dephosphorylates APC/C, thereby counteracting the activity of the mitotic kinase Cdc28.
210 onsensus among the rest of the population by counteracting the benefit of the intermediate state or m
211 iplet than in the singlet, thereby partially counteracting the bonding and dispersion components, whi
212 Viruses have evolved ways of preventing or counteracting the cascade of antiviral responses that do
213 stals and limits proinflammatory pathways by counteracting the cell-activating spleen tyrosine kinase
214 st, it subtly influences centriole length by counteracting the centriole-elongating activity of sever
215 th drier climatic conditions, to some extent counteracting the climate-driven shift towards wetter co
216 If so, complexity could provide an advantage counteracting the costs involved in maintaining larger n
219 le to maintain maximum biomass production by counteracting the decreasing P supply by a more efficien
220 tion studies of miR-133 revealed its role in counteracting the deleterious apoptotic effects caused b
221 ffects this process, and approaches aimed at counteracting the deleterious effects of early over- and
222 neuromuscular junction synaptic structure by counteracting the detrimental effects of long-term acety
224 modifier lymphoid-specific helicase (LSH) by counteracting the deubiquintination in proteasome pathwa
225 co-regulator is a new therapeutic target for counteracting the development of obesity, insulin resist
228 margin, increasing cell cohesion and thereby counteracting the effect of mitotic rounding on contact
231 arveyi acyl-ACP synthetase, replaced RpfB in counteracting the effects of high level RpfF thioesteras
232 As we found evidence for drug treatment counteracting the effects of IL-13 on the epithelium, we
233 n the presence of solutions containing salt, counteracting the effects, for example, charged lipids,
234 HPC ghrelin signaling increases meal size by counteracting the efficacy of various gut-derived satiat
235 th EGFR/HSP70/HSP90 through the DnaJ domain, counteracting the EGFR regulatory function of HSP90 by c
236 process that may diminish the risk of PML by counteracting the excess of immunosuppression that may o
237 y roles in neuromuscular function, including counteracting the expression of neonatal isoforms induce
238 activated translation of IkappaBzeta mRNA by counteracting the function of a translational silencing
239 Nociceptin exerts its antistress effect by counteracting the functions of corticotropin-releasing f
240 deubiquitinates and stabilizes PML, thereby counteracting the functions of PML ubiquitin ligases RNF
242 the efficiency of therapeutic approaches to counteracting the harmful impact of ZIKV(BR) in human ne
244 clearly highlight the importance of PA-X in counteracting the host innate and acquired immune respon
245 nt has emerged as an important mechanism for counteracting the host response to virus infection.
246 essory protein Vpu enhances virus release by counteracting the host restriction factor tetherin.
247 ls of OCT4 and its target gene ZEB1, thereby counteracting the increase of OCT4 induced by pemetrexed
248 ction over time, which has the potential for counteracting the increasing flood risk associated with
249 proper attachment of RCs to the PM, thereby counteracting the increasing membrane tension induced by
250 among children born at term, is relevant in counteracting the increasing use of this procedure, whic
251 ts to a novel upstream therapeutic target by counteracting the inflammatory processes in atrial fibri
254 de coupling mechanism in CaV1.1a operates by counteracting the limiting effects of exon 29 inclusion
255 exposure, resulting in a more rigid membrane counteracting the membrane-fluidizing effect of nZVI.
256 ipid ATPase), a P4-type ATPase, in a process counteracting the monogalactosyldiacylglycerol (MGDG) sh
257 ) and vitamin D3 was found more effective in counteracting the negative consequences of oxidative str
258 (Zostera marina) through a trophic cascade, counteracting the negative effects of agriculturally ind
259 tin ligase, ICP0, plays an important role in counteracting the negative effects of DNA-PK activation.
260 ic effect in rats with cirrhosis and ascites counteracting the negative effects of oxidative stress-
261 factor but also promotes differentiation by counteracting the negative influences of protein kinase
262 rather than inactivation, as a mechanism for counteracting the pleiotropic consequences of aberrant t
263 animals to assess histological damage, thus counteracting the principles of Replacement, Refinement
264 ression serves as an important mechanism for counteracting the reduction of genetic diversity in dome
266 ated status of cell-based therapies aimed at counteracting the skeletal and cardiac myopathy present
268 Thus, SAV1 promotes Hippo activation through counteracting the STRIPAK(SLMAP) PP2A phosphatase comple
269 density wave after near-infrared excitation, counteracting the suppression of order in the non-equili
270 a resolution-associated molecular pattern by counteracting the synthesis of proinflammatory cytokines
271 mperature as the inverse of T(4) , precisely counteracting the T(4) dependence; hence, thermal radian
273 bined attributes would be functional for (i) counteracting the unique loading patterns acting on the
276 nhibiting their gene-silencing functions and counteracting their role in linking stress sensing with
281 ture suggests a role for the cytoskeleton in counteracting these stresses, there has been no systemat
285 ects signs of balance loss, then it supplies counteracting torques at the hips to assist balance reco
286 p2 confines Pol II and Top1 at coding units, counteracting transcription leakage and aberrant hybrids
287 redicted that this response was effective at counteracting transformation independently of competing
288 cisely fine-tune endosomal F-actin levels by counteracting TRIM27 auto-ubiquitination/degradation and
289 and the discovery of therapeutic targets for counteracting tumor suppressor gene loss is needed.
292 hosphorylation following interactions with a counteracting tyrosine phosphatase regulates diverse phy
293 Resistance training was very effective in counteracting ULLS-induced alterations, indicating that
294 rably suppressed HIF1alpha, thus potentially counteracting undesirable effects of elevated tumor hypo
297 A silencing, and hence is a major target for counteracting viral suppressors of RNA-silencing protein
298 is expected that OHCs are more effective in counteracting viscous drag than providing elastic energy