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1 opically reminiscent of the adjacent natural cranial suture.
2 of FGFR2c to multiple FGFs expressed in the cranial suture.
3 osis of the coronal suture, as well as other cranial sutures.
4 the fibrous joints between the bones, termed cranial sutures.
5 l features caused by the premature fusion of cranial sutures.
6 th defect resulting from premature fusion of cranial sutures.
7 ed endochondral-like ossification within the cranial sutures.
8 nd results from the premature fusion of >/=1 cranial sutures.
9 al stem/progenitor cells are resident in the cranial sutures.
10 tween subjects guided by the location of the cranial sutures.
12 rtilage heterotopic ossification (HO) within cranial sutures and fontanels of the mouse model, leadin
13 ts in a more severe delay in ossification of cranial sutures and fontanels than occurs with Runx2 hap
14 We also observed premature fusion of the cranial sutures and low bone density in newborn FGFR3(G3
15 nalling dynamics, whereby development of the cranial sutures and sternum follows a morphogen mode, wh
16 NCCs impairs the formation of normal midline cranial sutures and, consequently, the overlying skin, r
17 zed by craniosynostosis (premature fusion of cranial sutures) and severe syndactyly of the hands and
18 h as the mandibular condyle, calvarial bone, cranial suture, and subcutaneous adipose tissue--have be
19 splasia characterized by short stature, wide cranial sutures, and increased bone density and fragilit
20 suture mesenchyme of patent, but not fusing, cranial sutures, and that noggin expression is suppresse
25 at differences in the morphology of selected cranial sutures between species that span the fish-tetra
26 new insights, both into normal and abnormal cranial suture biogenesis and into problems of broad int
27 arpenter syndrome implicates HH signaling in cranial-suture biogenesis--an unexpected finding, given
28 synostosis based on current understanding of cranial suture biology and molecular and developmental p
29 animal models and improved uncerstanding of cranial suture biology and pathology may lead to complem
32 l neural crest cells, giving rise to midline cranial suture cells that express keratinocyte-promoting
33 quencing (scRNA-seq) of normal neonatal mice cranial suture chondrocytes showed a Hedgehog (Hh) inact
34 to growth plate abnormalities and premature cranial suture closure because of precocious maturation
36 ovel molecule overexpressed during premature cranial suture closure in patients with craniosynostosis
38 hat the Mgp promoter is highly active at the cranial sutures, cranial base synchondroses, and nasal s
39 idermal hyperplasia and premature closure of cranial sutures (craniosynostosis) due to abnormal cell
42 trate the roles of osteoprogenitor cells and cranial suture-derived stem cells for proper calvarial g
44 reviously unsuspected role for Zic1 in early cranial suture development, potentially by regulating en
51 enetically determined disorders of premature cranial suture fusion (craniosynostosis) provide one rou
52 a skull deformity characterized by premature cranial suture fusion due to the loss of the GNAS gene a
54 nai1 and Snai2 mutations to enhance aberrant cranial suture fusion, demonstrating that genetic intera
61 mes of craniosynostosis (premature fusion of cranial sutures) have homologues in the CeTwist pathway.
63 Over-expression of Nell1 in the developing cranial sutures in both human and mouse induces craniosy
65 ative spatial transcriptomic analysis of the cranial sutures in vivo confirmed a positive association
67 fined by premature fusion of one or multiple cranial sutures, is a common congenital defect affecting
68 niosynostosis, the premature ossification of cranial sutures, is a developmental disorder of the skul
69 raniosynostosis, the premature fusion of the cranial sutures, is a heterogeneous disorder with a prev
70 st cells (NCCs), which normally form midline cranial suture mesenchymal cells that express keratinocy
71 e was de novo formation of tissue-engineered cranial suture, microscopically reminiscent of the adjac
72 enital disorder of premature ossification of cranial sutures, occurring in one of approximately every
76 ostosis, the premature fusion of one or more cranial sutures of the skull, provides a paradigm for in
83 ostosis results from premature fusion of the cranial suture(s), which contain mesenchymal stem cells
86 Cs, we successfully regenerated a functional cranial suture that corrects skull deformity, normalizes
87 ricular surfaces, pubic symphyseal face, and cranial sutures, to produce a multifactorial narrower ag