ライフサイエンスコーパス: crawling

1 performed in the course of fictive crawling (crawling).

2 ed for the different elements of exploratory crawling.

3 ns in the Drosophila larval body wall during crawling.

4 ion from the substrate in the course of cell crawling.

5 lved in E-selectin-mediated slow rolling and crawling.

6 is involved in Mac-1-dependent intravascular crawling.

7 abdominal segments switches the direction of crawling.

8 is a sufficient signal to induce healing by crawling.

9 tion of the EGFR, which triggers movement by crawling.

10 ls to constrain behavior to simple, rhythmic crawling.

11 P) as linear actuators to enable directional crawling.

12 new feature in our emerging understanding of crawling.

13 fly locomotion, but also crucial for larval crawling.

14 (LFA-1)- versus CD11b/CD18 (Mac-1)-mediated crawling.

15 es (67.4 +/- 9.6 mum), resembling neutrophil crawling.

16 local interoscillator coupling contribute to crawling.

17 late mesenchymal three-dimensional (3D) cell crawling.

18 rent from electrically evoked or spontaneous crawling.

19 intersegmental phase delays appropriate for crawling.

20 nderstanding of the mechanics of caterpillar crawling.

21 nsory inputs resulted in cessation of larval crawling.

22 reas cell 257 is an interneuron dedicated to crawling.

23 scillated with swimming also oscillated with crawling.

24 eletal proteins used during actin-based cell crawling.

25 um of position encoding during all phases of crawling.

26 les provided propulsion during bidirectional crawling.

27 t characterize key behaviors such as forward crawling.

28 , whereas P cells were unaffected throughout crawling.

29 hrough the lymphatic endothelium and luminal crawling.

30 istaltic waves of muscle contractions during crawling.

31 twice as many cells oscillated in-phase with crawling (188) compared with swimming (90).

32 erection is part of the contraction phase of crawling, a leech locomotive behavior.

33 elated with NMJ size and regulated by larval crawling activity, synapse excitability, postsynaptic re

34 k56), both of which are required to suppress crawling activity-dependent NMJ growth.

35 etween actomyosin cable contraction and cell crawling acts as a large-scale regulator to control the

36 sary and sufficient to initiate and maintain crawling after swimming.

37 roscopy that blood monocytes and neutrophils crawling along and adhering to the venous endothelium pr

38 ophils into lymphatic vessels and subsequent crawling along the luminal side of the lymphatic endothe

39 Ly6C(lo) monocytes, patrol blood vessels by crawling along the vascular endothelium.

40 experience were specific to cruising and not crawling, although both skills involve anti-phase coordi

41 ugh venular walls, such as leukocyte luminal crawling and cellular and molecular changes in leukocyte

42 tadhesion phase, which involves intraluminal crawling and diapedesis to the extravascular space, rema

43 de distinct forms of excitatory drive during crawling and differ in key transmission properties.

44 cremaster muscle, we separately examined the crawling and emigration patterns of monocytes and neutro

45 under dynamic flow conditions CXCL12-induced crawling and endothelial transmigration of Th1 cells was

46 rophil interactions and increased neutrophil crawling and extravasation in response to Ab-opsonized b

47 ntigen-1/alphaLbeta2 integrin for subsequent crawling and extravasation.

48 Depletion of LARG decreases leukocyte crawling and inhibits TEM.

49 KT2 is important for neutrophil adhesion and crawling and neutrophil-platelet interactions on activat

50 entical sensory inputs that sometimes elicit crawling and other times swimming.

51 ack loop promotes ICAM-1-mediated neutrophil crawling and paracellular transmigration.

52 that actin alone drives phenotypes like cell crawling and phagocytosis.

53 rupted at intervals by pause turns that halt crawling and redirect the trajectory of movement.

54 tic alternation between straight peristaltic crawling and reorientation events through lateral bendin

55 otor neuron bursting and coordination during crawling and restoring cacophony selectively in two pair

56 e actin-based protrusions contribute to cell crawling and seamless wound healing.

57 m food, resulting in longer bouts of forward crawling and suggesting that worms can use noise to modi

58 ward thrust during movement and suggest that crawling and swimming are similar processes, a compariso

59 s biogenic amines to switch between distinct crawling and swimming gaits.

60 H1(-/-) leukocytes were deficient in in vivo crawling and TEM in the postcapillary venules.

61 ar system in a manner distinct from standard crawling and thrashing assays.

62 Leukocyte crawling and transendothelial migration (TEM) are potent

63 lling on selectins but impaired intraluminal crawling and transendothelial migration.

64 cytosis, endothelial adhesion, intravascular crawling and transmigration.

65 A combination of crawling and undulation gaits allowed this robot to navi

66 Both crawling and walking delivered a significant number of r

67 The physical mechanism of plasmin action (crawling) and avoidance of inhibition is defined.

68 ce signals through PSGL-1 displayed aberrant crawling, and blockade of this domain protected mice aga

69 BBB endothelium supports neutrophil arrest, crawling, and diapedesis under physiological flow in vit

70 othelial expression of ICAM-1, intravascular crawling, and extravasation.

71 Wounds can also heal by cell crawling, and my colleagues and I have shown previously

72 helps to explain the inherent flexibility of crawling, and provides a foundation for understanding ot

73 robots with locomotion modes of peristalsis, crawling, and rolling.

74 velocity, decreased firm adhesion, aberrant crawling, and strongly reduced transmigration.

75 f Shp1 to study neutrophil arrest, adhesion, crawling, and transendothelial migration in vitro and in

76 Leukocyte adhesion, crawling, and transmigration are regulated by clustering

77 n, postadhesion strengthening, intravascular crawling, and transmigration, as each step necessitates

78 tangential surface drag coefficients during crawling are approximately 222 and 22, respectively, and

79 1-dependent slow rolling and Mac-1-dependent crawling are defective in P-Rex1(-/-) leukocytes, wherea

80 Thus, mechanisms underlying leukocyte crawling are important in regulating the inflammatory re

81 viscous drag forces, which are higher during crawling as compared to swimming in an aqueous buffer so

82 F-beta- and integrin-dependent lamellipodial crawling at the leading edges of the epidermal tongue.

83 We quantified crawling at the organism, segment, and muscle levels.

84 pedal (man and chicken) or quadrupedal mode (crawling-baby and cat).

85 t when the CNS was exposed to dopamine (DA), crawling became the exclusive locomotor pattern produced

86 expression in motor neurons regulates larval crawling behavior in a developmental stage-specific mann

87 simplex virus infection show a steady-state crawling behavior in between keratinocytes.

88 Long-range crawling behavior in CD14(dim)CD16(+) monocytes was abro

89 tical, we also showed that changes in larval crawling behavior in response to either hypoxia or hyper

90 n region between different types of observed crawling behavior in the dynamical phase diagram, such a

91 Analysis of the network that controls crawling behavior in the leech has clearly indicated tha

92 levels of biological organization, from the crawling behavior of Caenorhabditis elegans to the contr

93 The characteristic crawling behavior of Drosophila larvae consists of a ser

94 Here, we use the crawling behavior of the nematode Caenorhabditis elegans

95 Unlike T cells, which displayed vigorous crawling behavior on the endothelium, B cells remained s

96 ii infection, exhibited distinct rolling and crawling behavior, and accumulated within the vessel lum

97 A long-range crawling behavior, similar to the "patrolling" behavior

98 monstrated ICAM-1-dependent shape-change and crawling behavior.

99 as both necessary and sufficient for fictive crawling behavior.

100 step elongation-contraction cycle underlying crawling behavior.

101 oked synaptic transmission and alters larval crawling behaviour.

102 and myosin inhibitors affected the speed of crawling but not directed motion, whereas pertussis toxi

103 rsibly with a sucrose block) prevented overt crawling, but not swimming.

104 Many animal cells initiate crawling by protruding lamellipodia, consisting of a den

105 e motility mechanisms: horizontally oriented crawling, by which the bacterium moves lengthwise with h

106 analyses revealed a defective intravascular crawling capacity, resulting from increased affinity of

107 technique shows that the internal organs of crawling caterpillars slide past the body walls like pis

108 ize internal soft-tissue movements in freely crawling caterpillars.

109 we present a simplified physical model of a crawling cell, consisting of a droplet of active polar f

110 y resembles that seen in many other types of crawling cell, movement is generated by modulation of a

111 he solutions demonstrate that in the rapidly crawling cell, myosin concentrates at the rear boundary

112 nched network found at the leading edge of a crawling cell.

113 assembly powers protrusion in other types of crawling cell.

114 e biogenesis , plasma-membrane protrusion in crawling cells , and membrane trafficking from the Golgi

115 In addition, many crawling cells can translocate when myosin is inhibited

116 tant receptors activates the cytoskeleton of crawling cells for chemotaxis.

117 ations shows that leading edge protrusion in crawling cells increases membrane tension, which constra

118 In most crawling cells protrusion is driven by highly regulated

119 Crawling cells show many features of excitable systems,

120 In addition, some crawling cells when plated onto a stiff substrate will n

121 Inside of crawling cells, NMIIA-Fs form large macromolecular ensem

122 Some crawling cells, such as fish keratocytes, maintain a rou

123 usually produces finger-like projections of crawling cells.

124 a principal regulator of pseudopod growth in crawling cells.

125 direct role in actin network disassembly in crawling cells.

126 ary nucleator of new actin filaments in most crawling cells.

127 dynamical patterns observed in spreading and crawling cells.

128 om single protein polymer filaments to whole crawling cells.

129 ) myosin II and can regulate the motility of crawling cells.

130 During cytokinesis or eukaryotic cell crawling, contractile forces are generated inside the ce

131 sy regime cellular events such as spreading, crawling, contracting, and invading.

132 rement to maximise membrane curvature during crawling contractions.

133 ng force generated during either swimming or crawling correlate well with previously described gait-s

134 urons was performed in the course of fictive crawling (crawling).

135 itinated proteins, neurodegeneration, larval-crawling defect and early lethality.

136 d BMP signaling, synaptic growth, and larval crawling defects.

137 Movement by crawling depends on signaling by the EGF receptor (EGFR)

138 Using the quantitative model of larval crawling developed here we use the mutant-specific param

139 ractors corresponding to abrupt reversals in crawling direction.

140 gned planar excitation (SCAPE) microscopy in crawling Drosophila larvae to simultaneously track the p

141 nal dynamics of the proprioceptive system in crawling Drosophila, and demonstrate the utility of our

142 al requirement for ROCK in intralymphatic DC crawling during steady-state and inflammation.

143 PDI is required for neutrophil adhesion and crawling during tumor necrosis factor-alpha-induced vasc

144 Specifically, a transition from crawling dynamics to flipping behavior occurs at a Young

145 Brief excitation of CV motoneurons during crawling episodes resets the rhythmic activity of DE-3,

146 that matched periods observed during fictive crawling, even when potential ascending inputs from craw

147 ht posture while holding onto a support) and crawling experience as they cruised over variable distan

148 In the absence of crawling, few neutrophils maintained adhesive interactio

149 esults explain how the nucleus is moved in a crawling fibroblast and raise the possibility that force

150 rusion cycles and handmirror morphology of a crawling fibroblast, and others the steady gliding motil

151 of the main forces governing the C. elegans crawling gait on lubricated surfaces have been scarce, p

152 During the crawling gait, evoked by large external loads, comparabl

153 both LFA-1 and Mac-1 contribute to monocyte crawling; however, the LFA-1-dependent crawling in unsti

154 The package is divided into web-crawling, HTML-cleaning, de-identification and informati

155 postadhesion strengthening and intravascular crawling in a Mac-1-dependent manner.

156 e intravital imaging of alveoli revealed AMs crawling in and between alveoli using the pores of Kohn.

157 Mac-1 alone was responsible for neutrophil crawling in both unstimulated and TNF-alpha-activated ve

158 ersegmental phase delays, we induced fictive crawling in isolated whole nerve cords using dopamine (D

159 We show that TFP-mediated crawling in Pseudomonas aeruginosa consistently alternat

160 copy, we found immature B cells entering and crawling in sinusoids; these immature B cells were displ

161 one ganglion was removed from its neighbors, crawling in that ganglion emerged robust and stable, und

162 s, such as spontaneous symmetry breaking and crawling in the absence of external cues, and periodic a

163 activity, is sufficient to activate fictive crawling in the medicinal leech, and can exert its actio

164 generators (CPGs) control both swimming and crawling in the medicinal leech.

165 By eliciting swimming and crawling in the same preparation, we were able to identi

166 ocyte crawling; however, the LFA-1-dependent crawling in unstimulated venules becomes Mac-1 dependent

167 Actin-dependent crawling, in contrast, involves mutiple distinct molecul

168 We studied rhythmic behavior--larval crawling--in the genetically and developmentally tractab

169 ed, generates propagating activity as during crawling inDrosophilalarvae.

170 er experiments were conducted with a robotic crawling infant and an adult performing a walking sequen

171 utine of this kind, performing straight line crawling interrupted at intervals by pause turns that ha

172 Mesenchymal cell crawling is a critical process in normal development, in

173 Cell crawling is an inherently physical process that includes

174 ently, neutrophil adhesion is increased, but crawling is decreased.

175 We showed that Drosophila larval crawling is made up of a series of periodic strides.

176 ters obtained from the trajectories of a few crawling larvae.

177 initially poorly organized, and coordinated crawling-like behavior gradually emerges over the subseq

178 maximum intraburst firing frequencies during crawling-like motor patterns in semi-intact animals.

179 The embryo continues to exhibit bursts of crawling-like sequences until shortly before hatching, w

180 Traces of crawling locomotion are documented for the first time in

181 ructured arena allowed C. elegans to perform crawling locomotion in a controlled liquid environment.

182 Crawling locomotion of eukaryotic cells is achieved by a

183 ate the nicotinergic signaling that controls crawling locomotion of KCs.

184 Consistent with the role of Mac-1 in crawling, Mac-1 block (compared with LFA-1) was also sig

185 report a novel visceral-locomotory piston in crawling Manduca sexta larvae, in which the gut slides f

186 Intracellular crawling may contribute to optimal lymphocyte positionin

187 as a mechanically passive substrate for the crawling mesoderm and to secrete various growth factors

188 We show controlled triggering of specific crawling modes and find that targeted neurostimulation i

189 Arp2/3-nucleated actin filaments drive crawling motility and phagocytosis in animal cells and s

190 s considered to form a simpler, yet similar, crawling motility apparatus.

191 Crawling motion is ubiquitous in eukaryotic cells and co

192 Crawling motion mediated by retrograde and direct waves,

193 The crawling motion of Dictyostelium discoideum on substrata

194 processes in eukaryotic cells, including the crawling motion of the whole cell, rely on the growth of

195 , and those DsRed(+)/Ly6G(+) cells exhibited crawling motion with a higher velocity compared with the

196 ndritic and the axonal compartment of larval crawling motoneurons.

197 Research on the circuit that controls the crawling motor behavior in leeches indicated that motone

198 Crawling movement in eukaryotic cells requires coordinat

199 The crawling movement of nematode sperm requires coordinatio

200 resulted in flattening of the T cells and a crawling movement on the FLS surface.

201 icients to predict the forces generated by a crawling nematode.

202 These results show that the swimming and crawling networks are driven by both multifunctional and

203 The crawling neutrophils required the platelet-paved endothe

204 (2) integrin clusters at the leading edge of crawling neutrophils, allowing capture of circulating er

205 Crawling neutrophils, although preferentially crossing t

206 The light-driven crawling of a molecular crystal that can form three phas

207 segmentally coordinated during bidirectional crawling of Drosophila larvae.

208 Crawling of eukaryotic cells on flat surfaces is underla

209 The slow mesenchymatous mode, like crawling of fibroblasts, relies on maturation of adhesio

210 ess triggered GEF-H1-dependent spreading and crawling of neutrophils and relocalization of GEF-H1 to

211 ening, spreading, and directed mechanotactic crawling of PMNs under flow conditions-involved HPK1 in

212 scade, which involves rolling, sticking, and crawling of the leukemic cells on the endothelium.

213 e recordings, we demonstrated "intracellular crawling" of lymphocytes entering into one endothelial c

214 on distribution along the membrane of a cell crawling on a flat substrate.

215 simulation environment) of mesenchymal cells crawling on a two-dimensional substrate.

216 Thus, beta2 integrin-mediated neutrophil crawling on endothelial ICAM-1 and ICAM-2 is a prerequis

217 For cells crawling on hard surfaces, significant insights into mot

218 In this model of neutrophils crawling on immobilized platelets, very few NETs were ob

219 ear stress, cell morphology alterations, and crawling on intercellular adhesion molecule 1 (ICAM-1)-e

220 expressed ICAM-1 and DC-expressed ROCK in DC crawling on lymphatic endothelium.

221 embly in the lamellipodium in adherent cells crawling on planar 2-dimensional (2D) substrates.

222 flow of primary human effector T lymphocytes crawling on substrates coated with ligands of integrins

223 dulation frequency, and wavelength of worms, crawling on surfaces show nonmonotonic behavior with inc

224 ditis elegans, between swimming in water and crawling on surfaces, adapts its locomotory gait to surr

225 h act downstream of capturing, adhesion, and crawling on the blood vessel wall and require Galphai si

226 -induced neutrophil spreading and subsequent crawling on the endothelium to sites of transmigration.

227 the liver microvasculature of healthy mice, crawling on the luminal side of endothelial cells, but t

228 t coordinated motion into the void by active crawling on the substrate and by constricting a supracel

229 orces and the nematode's bending force while crawling on the surface of agar gels within a preexistin

230 rin-mediated events such as rapid arrest and crawling on the surface of the endothelium and transmigr

231 membrane, and we detected detached podocytes crawling on the surface of the tubular epithelium and oc

232 Cell crawling on two-dimensional surfaces is a relatively wel

233 ations in shear-resistant adhesion to, or in crawling on, primary endothelial cells under physiologic

234 gh these arrested T cells polarize and start crawling, only few remain firmly adherent over time.

235 ts of neutrophil rolling, firm adhesion, and crawling onto the EC surface before extravasating by bre

236 zation of spreading cells, leading to steady crawling or bipedal motion, and bistability, where persi

237 In just 1 min of crawling or walking, 10(3)-10(4) resuspended FBAPs can d

238 revention of Ly6C(low) monocyte development, crawling, or retention in Nr4a1(-/-), Itgal(-/-), and Tl

239 downregulate adhesion and polarity proteins, crawling over and between neighboring cells to converge

240 eo-taped and quantified for locomotion (e.g. crawling pattern and speed) using ImageJ software.

241 ccurately account for the complex and unique crawling patterns exhibited by individual Drosophila lar

242 n-blocking Abs, we show that these different crawling patterns were due to CD11a/CD18 (LFA-1)- versus

243 te that neutrophil arrest, polarization, and crawling required G-protein-coupled receptor-dependent a

244 Cell crawling requires the generation of intracellular forces

245 crawl motor program and that the kernel for crawling resides within each segmental ganglion.

246 Crawling results from successive bouts of elongation and

247 labeled ground truth, initial seeds and the crawling results reported in this article.

248 The expression of swimming versus crawling rhythms is regulated by sensory input.

249 the fabrication of machines, we developed a crawling robot that folds itself.

250 an example modular reconfigurable IPMC soft crawling robot to demonstrate feasibility.

251 est that the central network responsible for crawling sends a reafferent signal onto the T cells, con

252 ctivity are poorly organised and coordinated crawling sequences only begin to appear after a further

253 h of execution till the end of the 20-h long crawling session as compared with the cumulative precisi

254 h of execution till the end of the 20-h long crawling session as compared with the cumulative precisi

255 Our experiments reveal that crawling speed is an increasing function of both cell si

256 transcription factors code, controls larval crawling speed.

257 eversals, a density-dependent switch between crawling speeds, and taxis towards neighboring worms.

258 e-derived spermatids that cannot activate to crawling spermatozoa, although spermatids from mutant ma

259 activate from a round spermatid to a mature, crawling spermatozoon.

260 as gripping, lifting, or motility (walking, crawling, swimming, and flying).

261 ated chemokine-induced adhesive filopodia on crawling T lymphocytes that scan the endothelial surface

262 h the existing state-of-the-art adaptive web crawling technology.

263 in novel, open-source data sets through web crawling, text mining, and social media analytics, prima

264 rns; and (3) an intermittent interruption to crawling that determines the time-dependent transition b

265 contractile waves during cell spreading and crawling that is only dependent on stick-slip adhesion a

266 fibroblasts showed that during spreading and crawling the lamellipodium undergoes periodic contractio

267 The alternative option, blindly crawling the whole web, has proven inefficient and unaff

268 During crawling, the calculated internal bending force is time-

269 lapse imaging of neutrophil-like HL-60 cells crawling through collagen matrices.

270 ely predictive numerical simulations of cell crawling thus have multiple scientific, medical, and tec

271 migration under flow conditions and reduced crawling time, velocity, and lateral migration distance

272 necessary and sufficient to transition from crawling to swimming and to inhibit a set of crawl-speci

273 t in HEVs but showed perturbed intravascular crawling to transmigration sites and compromised diapede

274 tro evidence, is dispensable for sensing and crawling toward wound cues.

275 ted endothelial cells (ECs), tight adhesion, crawling towards EC junctions and transendothelial migra

276 Anatomical details recognizable in the crawling traces show that no clothing was present betwee

277 rophil adhesion in vivo; however, neutrophil crawling, transmigration, and chemotaxis were reduced in

278 brogate, neutrophil adhesion, spreading, and crawling under static conditions.

279 e receptors migrate against this gradient by crawling under the agarose spots towards their centre.

280 Such experiments show that crawling uses a combination of actin treadmilling (polym

281 tant for neutrophil recruitment, reduced the crawling velocities of neutrophils within vessels, and m

282 chanism to regulate surface contact area and crawling velocity within different environments.

283 duces muscle stiffness, and decreases larval crawling velocity.

284 hes between distinct forms of locomotion, or crawling versus swimming, when transitioning between sol

285 ext, influenza A virus infection impaired AM crawling via the type II interferon signaling pathway, a

286 diverse underwater locomotion modes, such as crawling, walking, jumping, and swimming, by local defor

287 When crawling was blocked by inhibition of EGFR signaling, th

288 the increased Mac-1 adhesiveness, neutrophil crawling was impaired in CD45E613R mutant compared with

289 Neutrophil crawling was mediated by endothelial ICAM-1 and ICAM-2 a

290 mbrane potential of CV was manipulated while crawling was monitored through the rhythmic activity of

291 ntitative analysis indicated that DA-induced crawling was not significantly different from electrical

292 plain force production during nematode sperm crawling, we constructed a mathematical model that simul

293 endent IPSPs during dopamine-induced fictive crawling, whereas P cells were unaffected.

294 cific parameters to robustly simulate larval crawling, which allows estimating the feasibility of lab

295 mpetent to produce DA-induced robust fictive crawling, which typically lasted uninterrupted for 5-15

296 idence for a widely distributed mode of cell crawling with a single evolutionary origin.

297 n characteristics from free swimming to slow crawling with increasing confinement so that it was not

298 ocal oscillator coupling, we induced fictive crawling (with DA) in a single oscillator within a chain

299 ed mode of locomotion--"body-friction legged crawling" with body drag, friction-dominated leg thrust,

300 ocytes have been shown to undergo long-range crawling within the lumen of the microvasculature, which