ライフサイエンスコーパス: crescent

1 and agricultural colonists from the Fertile Crescent.

2 mpared to samples from the Neolithic Fertile Crescent.

3 again at the representation of the monocular crescent.

4 icultural village development in the Fertile Crescent.

5 rley and early forms of wheat in the Fertile Crescent.

6 (BF-1) expands from nasal retina into the VT crescent.

7 na corresponding to the myopic peripapillary crescent.

8 he founder crops domesticated in the Fertile Crescent.

9 olated from other populations of the Fertile Crescent.

10 c, when farming expanded west of the Fertile Crescent.

11 as most prominent nasally and in eyes with a crescent.

12 docytes and in podocytes entrapped in pseudo-crescents.

13 3.9) linked to the percentage of glomerular crescents.

14 oliferation, which ultimately forms cellular crescents.

15 ach dimer contains two separate and complete crescents.

16 these buttons were packed with budding viral crescents.

17 tion, with macrophages also most numerous in crescents.

18 At day 15 of disease, WT mice had glomerular crescents (37%+/-5%), severe proteinuria, and a 6-fold i

19 Here we show that Crescent, a dorsal protein, can compensate for the loss

20 ar crescents and close to the edge or rim of crescents; a similar labeling pattern was found for the

21 d in an extra-embryonic region, the germinal crescent, after approximately 18 h of incubation.

22 increased glomerular thrombosis, glomerular crescents, albuminuria, serum urea, and glomerular neutr

23 We now find that Crescent also regulates the BMP pathway.

24 s in the Southern Levant part of the Fertile Crescent, an area with a high proportion of the total ge

25 genitor cells were isolated from the cardiac crescent and 2 subsequent stages of heart development: t

26 stications of barley; one within the Fertile Crescent and a second 1,500-3,000 km farther east.

27 to the origin of barley--one in the Fertile Crescent and another farther east, possibly at the easte

28 ,000 years before the present in the Fertile Crescent and became a founder crop of Neolithic agricult

29 When co-injected, Crescent and Chordin proteins greatly synergized in the

30 ) mesoderm and in pharyngeal endoderm at the crescent and early somite stages.

31 t cultivated 10,500 years ago in the Fertile Crescent and is one of the founder crops of Eurasian agr

32 f A17 was also required for the formation of crescent and IV structures.

33 to regulate early expression in the cardiac crescent and later segmental expression in the developin

34 c pastoral agriculturalists from the Fertile Crescent and Northern Africa, as well as more recent mig

35 n wheat landraces collected from the Fertile Crescent and surrounding areas carried the mutation (C)

36 outside factories and inside factories near crescents and close to the edge or rim of crescents; a s

37 eveloped diffuse proliferative GN with focal crescents and glomerulosclerosis.

38 This mutant, however, developed crescents and had normal A11 localization despite failin

39 ffold protein-coated membranes that resemble crescents and immature virions devoid of viroplasm were

40 us homologs, contributes to the formation of crescents and immature virions.

41 r) mice had a complete absence of glomerular crescents and marked reductions in glomerular hypercellu

42 teins known to be necessary for formation of crescents and the only one synthesized early in infectio

43 synthetic procedures for the preparation of crescent (and helical) aromatic oligoamides developed in

44 he founder crops domesticated in the Fertile Crescent, and currently represent crops of major economi

45 nsiently during establishment of the cardiac crescent, and extinguished from the heart before CNC inv

46 lation of large virosomes, detached membrane crescents, and empty immature virions.

47 omerular injury, the development of cellular crescents, and the activation and proliferation of PECs

48 ins are induced at 12 h postinfection (hpi), crescents appear at the periphery of the electron-dense

49 The crescents are highly unusual, open-ended membranes, and

50 Crescents are rare in primary membranous nephropathy and

51 nd that in pheromone-treated cells, receptor crescents are visible before detectable polarization of

52 sequestering Wnts, such as Frz-B, WIF-1 and Crescent, are poor mimics of the inductive and patternin

53 defined genes encoding the sFRPs Frzb-1 and Crescent as transiently and locally expressed in the pri

54 icated a close association of A17 and D13 in crescents, as well as in vesicular structures when cresc

55 ntain numerous stemmed projectile points and crescents associated with a variety of marine and aquati

56 0 (P </= .001) and presence of peripapillary crescent at all locations except T1500 and T2250 (P </=

57 ents SEC-5, -6, -8, and -15 form a delimited crescent at the apical plasma membrane.

58 neage cells, BASL accumulates in a polarized crescent at the cell periphery before division, and then

59 arrest and crawl slowly with a dense ICAM-1 crescent at the leading edge.

60 One consisted of short crescents, at the surface of dense masses of viroplasm,

61 an anterior domain reminiscent of a cardiac crescent before forming a beating cardiac tissue near a

62 ees centrally, and a far temporal peripheral crescent bilaterally, and ERGs were nondetectable.

63 the cell shape of Parachlamydia and that the crescent body is not a developmental stage, but an artef

64 essential role not only in the formation of crescents but also in their subsequent enclosure to form

65 uggest that it participates in elongation of crescents by the addition of ER membrane to the growing

66 folding proteins are bound inside the large crescent cleft, thus enabling their access to inward-fac

67 The result is a bubble-crescent configuration, which alternates between two deg

68 The crescents consist of a lipoprotein membrane and an outer

69 Crescents consisting of a single lipoprotein membrane wi

70 A plasma membrane-associated polarity crescent defined by BREAKING OF ASYMMETRY IN THE STOMATA

71 We previously found that crescents derive from the aberrant proliferation and mig

72 n BM was transferred from WKY to Lewis rats, crescents developed in 35 +/- 9% of glomeruli 10 d after

73 The Fertile Crescent domestication contributed the majority of diver

74 communities emerged in parts of the Fertile Crescent during the tenth millennium and early ninth mil

75 For this reason and the crescent employment of mass spectrometry (MS) techniques

76 Crescents enlarge to form spherical immature virions, wh

77 n begins at the lateral sides of the cardiac crescent, excluding early differentiating regions, and c

78 sing that began in 2011, the greater Fertile Crescent experienced the most severe drought in the inst

79 In the eastern Fertile Crescent exploitation of legumes, fruits, nuts, and gras

80 e a primary mouth to embryos in which Frzb-1/Crescent expression has been inhibited.

81 ;face transplants', we show that frzb-1 and crescent expression is specifically required in the prim

82 Crescent expression was increased by the BMP antagonist

83 apillary proliferation, sometimes resembling crescents, following rapid and severe podocyte loss.

84 1 versus 8.0 +/- 1.9 controls; P < 0.05) and crescent formation (0% CNTO 1081 versus 60% controls; P

85 noncomplementing cell lines with defects in crescent formation and A11 localization.

86 ignificantly reduced glomerular necrosis and crescent formation and abrogated monocyte, macrophage, a

87 of nephrotoxic nephritis resulted in reduced crescent formation and decreased proteinuria.

88 wo-domain architecture and functions in both crescent formation and its enclosure to form immature vi

89 Crescent formation and renal MMP and growth factor expre

90 ange of kidney lesions, including glomerular crescent formation and renal tubule defects in early dis

91 es in the glomeruli; ii) marked reduction in crescent formation and sclerotic glomeruli; iii) decreas

92 ytes/macrophages for glomerular necrosis and crescent formation in a renal ANCA-associated vasculitis

93 unction, which, histologically, manifests as crescent formation in most glomeruli.

94 Crescent formation requires a group of proteins that are

95 nts, as well as in vesicular structures when crescent formation was prevented.

96 ion of glomerular leukocytes, and glomerular crescent formation).

97 s, focal necrotizing glomerulonephritis with crescent formation, and glomerular infiltration by T cel

98 kappaB activation positively correlated with crescent formation, and nuclear phospho-p65 staining sho

99 zed by proliferative glomerulonephritis with crescent formation, and tubulointerstitial disease.

100 xhibited pronounced glomerulonephritis, with crescent formation, as well as tubulointerstitial diseas

101 membranes, which resembled the beginnings of crescent formation, at their periphery.

102 lomerular proliferative lesions with de novo crescent formation, findings that are linked with decrea

103 e recently identified as being essential for crescent formation, including the A6 protein of vaccinia

104 he density of CCL18(+) cells correlated with crescent formation, interstitial inflammation, and impai

105 While a cognate N domain is not required for crescent formation, it is required for virion formation,

106 ackground leads to significant reductions in crescent formation, macrophage infiltration, Fc receptor

107 esangial expansion, capillary proliferation, crescent formation, necrosis, wire loops, fibrosis, tubu

108 o other proteins that are required for viral crescent formation, profoundly decreased the stability o

109 an A2AR agonist, the glomerular cellularity, crescent formation, sclerotic glomeruli, and tubulointer

110 uding inhibition of albuminuria and cellular crescent formation, similar to the renal benefits observ

111 ionally, the connexin 43+/- mice showed less crescent formation, tubular dilation, monocyte infiltrat

112 Trp53-deficient mice, with the exception of crescent formation, which was not influenced by nutlin-3

113 l cell TLR4 stimulation increases glomerular crescent formation, with a mean of 21% and 25% in the tw

114 spicuous at sites of glomerular necrosis and crescent formation, with macrophages also most numerous

115 nd focal necrotizing glomerulonephritis with crescent formation.

116 iscovered that it plays an important role in crescent formation.

117 that correlated significantly with eGFR and crescent formation.

118 acement, vacuolization, and hypertrophy with crescent formation.

119 cterized by glomerular necroinflammation and crescent formation.

120 ent parietal epithelial cell hyperplasia and crescent formation.

121 isite for PEC proliferation and migration in crescent formation.

122 We show that Frzb-1/Crescent function locally promotes basement membrane dis

123 primary mouth) is seen after loss of Frzb-1/Crescent function to that seen after temporally and spat

124 of ecogeographical conditions in the Fertile Crescent, has valuable "left behind" adaptive diversity

125 roposition from its parental gene, Infertile crescent (Ifc), and integrated into heterochromatic regi

126 ucial for the crop's spread from the Fertile Crescent), illustrated complexities in GxE effect direct

127 However, no viral membrane crescents, immature virions, or mature virions were prod

128 e depletion reduced the number of glomerular crescents, improved renal function, and reduced proteinu

129 emained restricted to a cortical cytoplasmic crescent in blastomeres of 2-, 4- and 8-cell embryos.

130 MOEP19 cortical oocyte domain as a cortical crescent in blastomers suggests an intrinsic pre-pattern

131 lizes like the protein it encodes in a basal crescent in mitosis.

132 n the Mediterranean Basin and in the Fertile Crescent in relation to the past and current climate.

133 fferentially to the nucleus and a peripheral crescent in self-renewing cells and their sisters after

134 ical defect matches the myopic peripapillary crescent in size and shape, indicating that fill-in of t

135 As early farming spread from the Fertile Crescent in the Near East around 10,000 years before the

136 injection of anti-MPO IgG induced glomerular crescents in >60% of glomeruli in 129S6/SvEv and CAST/Ei

137 of nephrotoxic globulin, WKY rats developed crescents in 80 +/- 2% of glomeruli at day 10, whereas n

138 The presence of glomerular crescents in allograft biopsies had a significant negati

139 helial cells (PEC) are major constituents of crescents in crescentic glomerulonephritis.

140 te mutant Canoe protein fails to form apical crescents in dividing neuroblasts in vivo, and the lack

141 on and reduce the frequency and extension of crescents in extracapillary GN.

142 ocess, inhibits the formation of apical aPKC crescents in neuroblasts.

143 contribute to the formation of both cellular crescents in rapidly progressive GN and sclerotic lesion

144 In NTN, the ratio of crescents in the transplanted kidney to the native kidne

145 aits of species originating from the Fertile Crescent, including those for which there is archaeologi

146 emarkably, N1 also synergizes with WIF-1 and Crescent, indicating that N1 signals independently of C1

147 a-catenin signaling by Dickkopf-1 (Dkk-1) or Crescent initiates cardiogenesis in vertebrate embryos.

148 ent trabecular outflow system, so there is a crescent interest in increasing trabecular meshwork outf

149 in expansion of agriculture from the Fertile Crescent into diverse environments across the Mediterran

150 t Neolithic lifeways spread from the Fertile Crescent into Europe around 9000 BCE, reaching northwest

151 In sum, Crescent is a new component of the D-V pathway, which fu

152 Crescent is a secreted Frizzled-Related Protein (sFRP) k

153 The formation of a myopic crescent is accompanied by loss of metabolic activity in

154 es and actin, respectively, and the polarity crescent is the unifying landmark that is both necessary

155 Crescent knock-down increased the expression of BMP targ

156 irus-induced spherule-like structures, while crescent-like structures are formed in ESCRT-III deletio

157 cross-section morphologies ranged from large crescent-like to small ribbon-like shapes, also had the

158 ing events are visualized by biosensors in a crescent-like zone at the plasma membrane.

159 Thus, Crescent loss-of-function is compensated by increased ex

160 tivity (c-FLI) in the central, external, and crescent lPBN, and there was a strong correspondence bet

161 we hypothesized that urinary sCD163 shed by crescent macrophages correlates with active glomerular i

162 e N-terminal or central loop region affected crescent maturation and the immature virion (IV)-->matur

163 ading to impaired differentiation and failed crescent maturation.

164 n-associated collapses (for example, Fertile Crescent, Maya and Anasazi) or the lack thereof (Japan a

165 le is known regarding the composition of the crescent membrane or its mode of formation.

166 L2 mutant revealed abortive formation of the crescent membrane.

167 indicated that A11, like L2, associated with crescent membranes and immature virions during normal in

168 Crescent membranes are the first viral structures that c

169 in poxvirus morphogenesis, the formation of crescent membranes, occurs within cytoplasmic factories.

170 required for the formation or elongation of crescent membranes.

171 lular membranes but by forming and extending crescent membranes.

172 epend on autocrine Fgf8 signaling in cardiac crescent mesoderm.

173 We found that the meiotic crescent MIC has a specific chromosome interaction patte

174 egmental necrotizing glomerular lesions with crescents, mimicking a small vessel vasculitis such as A

175 Several assays indicate that Frzb-1 and Crescent modulate primary mouth formation by suppressing

176 ization, solid particles with the shape of a crescent moon are formed; removal of fluorocarbon oil yi

177 erse amphiphilic particles in the shape of a crescent-moon and use these particles to stabilize oil d

178 sedentary agrarian societies in the Fertile Crescent more than 10,000 years ago.

179 , and others the steady gliding motility and crescent morphology of a fish keratocyte.

180 ow showed accelerated disease with increased crescents, necrosis, glomerular monocytes, and renal IL-

181 s of glomerular cell proliferation, cellular crescents, neutrophils, fibrinoid necrosis, and tubuloin

182 mission electron microscopy: neither typical crescents nor immature virions were detected in the abse

183 ction in serum cystatin-C levels and reduced crescent numbers compared with WT mice, whereas PodMRKO

184 Although the detached crescents observed upon loss of A30 or G7 echo those see

185 Moreover, iCPCs injected into the cardiac crescent of mouse embryos differentiated into cardiomyoc

186 ency of iCPCs via injection into the cardiac crescent of mouse embryos.

187 m RGCs in the peripheral ventrotemporal (VT) crescent of the retina.

188 rrestin-1 levels in podocytes retrieved from crescents of patients with proliferative glomerulopathie

189 Indeed, expanded crescents of the Nup107-160 complex encircled unattached

190 nology of dairying beginning in the 'Fertile Crescent' of the Near East and its spread across Europe.

191 and found significant linkage to glomerular crescents on chromosome 2 (Crgn8, LOD = 3.8).

192 otein Prickle-like 2 (Pk2) is distributed in crescents on the medial sides of vestibular epithelial c

193 , the viral membrane is first discerned as a crescent or circle lacking obvious continuity with a cel

194 l molecular strands that adopt well-defined, crescent or helical conformations.

195 ssipated such that PSGL-1 was localized in a crescent or ring away from the cell periphery, and F-act

196 Crescent overexpression dorsalized whole embryos but not

197 the presence of a line of polarity reversal, crescent position is not altered between hair cells of o

198 nt findings that the WNT inhibitors Dkk1 and crescent possess cardiac-inducing activities led to the

199 Crescent protein lost its dorsalizing activity in Chordi

200 olding (the molding of membranes through the crescent protein shape) and membrane insertion (also cal

201 ue is damaged by the development of a myopic crescent, rather than simply translocated in a temporal

202 LCrgn1,2) produced markedly fewer glomerular crescents, reduced macrophage infiltration, and decrease

203 ut not ventral half-embryos, indicating that Crescent requires a dorsal component to exert its anti-B

204 ent results indicate that the characteristic crescent shape of Caulobacter crescentus depends upon an

205 h affinity (K(a) >10(7) M(-1)), and that the crescent shape of coralyne appears necessary for poly(A)

206 binding compounds is that they should have a crescent shape that closely fits the helical twist of th

207 formational changes that allow it to adopt a crescent shape that now complements the minor groove str

208 rgy-minimized state, it adopts a more planar crescent shape when bound in the minor groove of the DNA

209 The holoenzyme adopts an elongated crescent shape with an R(G) of approximately 65.3 A and

210 -loop-helix repeats arranged into an overall crescent shape.

211 Atg17 is crescent shaped with a 10 nm radius of curvature.

212 ffect of the outflow electrons generates the crescent-shaped agyrotropic electron distributions, whic

213 t completely denuded of RPE, and there was a crescent-shaped area of photoreceptor degeneration or at

214 dal oculomotor complex were distributed in a crescent-shaped band that lined the ventral and rostral

215 Crescent-shaped BAR domains are generic actors in the cr

216 , such as wedge-like amphipathic helices and crescent-shaped BAR domains, are required for bending me

217 Shallow hydrophobic insertions and crescent-shaped BAR scaffolds promote membrane curvature

218 Polymeric spirals of crescent-shaped BAR-domain superfamily proteins are tout

219 The structure reveals a crescent-shaped base made up of the amino-terminal, midd

220 studies of prokaryotic proteins, revealing a crescent-shaped base made up of the amino-terminal, PAZ,

221 The concave surface of the crescent-shaped Bin-amphiphysin-Rvs (BAR) domain is post

222 The crescent-shaped bin-amphiphysin-rvs (BAR) domains remode

223 In both complexes, the crescent-shaped BMVC recruits a flanking DNA residue to

224 his fascinating zigzag-shaped pattern yields crescent-shaped diffraction pattern.

225 bedding in the lipid bilayer and the charged crescent-shaped dimer acting to "scaffold" membrane curv

226 vesiculates lipid membranes in vitro via its crescent-shaped dimer and four amphipathic helices that

227 f PICK1 (PICK1-PDZ) to the homology-modeled, crescent-shaped dimer of the PICK1-BAR domain using mult

228 ysin/Rvs (F-BAR) domain family proteins form crescent-shaped dimers, which can bend membranes into bu

229 aorbital nerve afferents displayed a similar crescent-shaped distribution, suggesting they drive thes

230 he FIP200 coiled coil projects away from the crescent-shaped FIP200 N-terminal domain dimer.

231 Their active sites are located in a crescent-shaped groove on the barrel's outer surface, wh

232 The crescent-shaped HelD simultaneously penetrates deep into

233 FKBP26 is a crescent-shaped homodimer.

234 arrel with a hydrophobic interior supports a crescent-shaped hydrophilic active site on its outer sur

235 filament inclusion disease, and annular and crescent-shaped inclusions were seen in both conditions.

236 I-BAR proteins contain an all-helical, crescent-shaped IRSp53-MIM domain (IMD) dimer that is be

237 (ER) throughout the cell and at the edges of crescent-shaped IV precursors.

238 vaccinia virus begins with the appearance of crescent-shaped membrane precursors of immature virions

239 on of an N-terminal domain homologous to the crescent-shaped membrane-tubulating EFC/F-BAR domains an

240 virus structures except for occasional short crescent-shaped membranes and electron-dense lacy struct

241 Crescent-shaped membranes were continuous with the endop

242 Pus10 is a crescent-shaped molecule with two domains, the universal

243 nce of RNA synthesis, Pat1b redistributes to crescent-shaped nucleolar caps.

244 tructure of the complex reveals an elongated crescent-shaped particle in which two Mdm12 subunits occ

245 ingle particle electron microscopy reveals a crescent-shaped particle that bears striking resemblance

246 ading sporozoites into host cells, forming a crescent-shaped patch that fully resembles the electron-

247 tended conformation, Gemin2 wraps around the crescent-shaped pentamer, interacting with all five Sm p

248 biogenesis, before the development of short crescent-shaped precursors of the viral envelope.

249 The VLR genes encode for crescent-shaped proteins that use variable beta-strands

250 ural tube precursors are present in a broad, crescent-shaped region of the gastrula.

251 n addition to forming canonical eight-repeat crescent-shaped RNA-binding domains found in classical P

252 s show that the Zf-GRF fold is typified by a crescent-shaped ssDNA binding claw that is flexibly appe

253 The structure of Csa2 reveals a crescent-shaped structure unexpectedly composed of a mod

254 conserved dimeric module characterized by a crescent-shaped structure whose intrinsic curvature, fle

255 demonstrated the importance of the charged, crescent-shaped surface and the N-terminal amphipathic h

256 II: the ZnF-DNA binding domain (DBD) forms a crescent-shaped surface used for DNA end recognition whi

257 t, with circular receptive-field centers and crescent-shaped surrounds (0.63 degree offset) that had

258 ElFFF was able to fractionate the EVs, and a crescent-shaped trend was found for the retention time w

259 rom Italy, these specimens have a flattened, crescent-shaped ulna with a long axis perpendicular to t

260 step process, starting with the formation of crescent-shaped viral membranes, followed by their enclo

261 chanism that explains how the characteristic crescent-shaped, asymmetrical lumina form in UDH.

262 th a novel linker helix, form an integrated, crescent-shaped, symmetrical dimer.

263 In early stages, this region appears crescent-shaped, while advanced stages show a ring-like

264 The CT crescent sign is a highly sensitive and specific marker

265 The CT crescent sign was highly sensitive (85.7%) and specific

266 The CT crescent sign was positive in 7 patients (6.0%), 6 (5.1%

267 artment were assessed for the presence of a "crescent sign" (evidence of significant subinternal limi

268 Of the 110 patients without a CT crescent sign, 88 (75.1%) patients did not have TS, 21 h

269 ant-based subsistence in the eastern Fertile Crescent (southeast Turkey, Iran, and Iraq) focused on t

270 fields in the geographic area of the Fertile Crescent, spanning the Aceramic Neolithic [10,000 calibr

271 -oscillations (SACOs) in the forming cardiac crescent (stage E7.75) prior to overt beating.

272 Results demonstrated that, at cardiac crescent stages, HCN4 marks the first heart field, with

273 Fabrication provides good control over the crescents' structural properties which enables tuning of

274 Most importantly, we identified novel Gat1p crescent structures that are formed in the presence of o

275 rn Europe; the Middle East and Mediterranean crescent; sub-Saharan Africa; India; China; and southeas

276 at included the external lateral and lateral crescent subdivisions of the lateral PB more than double

277 coordinated between adjacent cells, and the crescents subsequently are lost by E18.5.

278 nduced NCGN (16.7%+/-6.0% versus 2.4%+/-1.7% crescents), suggesting that IL-1beta is a critical infla

279 also required at later stages, when membrane crescents surround virosomal contents and develop into i

280 but pheromone induces its polarization into "crescents" that cap the future mating projection.

281 ing the origin of agriculture in the Fertile Crescent, the broad spectrum of wild plant species explo

282 ome patients with membranous nephropathy and crescents, the crescentic lesion may be due to a distinc

283 ells correlated with a single or no LGN-NuMA crescent, tilted spindles, and the development of latera

284 e of chickpea from the Mediterranean/Fertile Crescent to Central Asia, and probably in parallel from

285 ical Partner of Inscuteable (Pins)-G alpha i crescent to divide asymmetrically, but the link between

286 se phenotypes is explained by the ability of Crescent to inhibit Tolloid metalloproteinases, which no

287 METHODS AND The CRESCENT trial (Calcium Imaging and Selective CT Angiogr

288 s, which are generated in the ventrotemporal crescent (VTC) of the retina, specifically express Boc,

289 al RGCs are restricted to the ventrotemporal crescent (VTC).

290 Enzyme kinetic studies showed that Crescent was a competitive inhibitor of Tolloid activity

291 a region resembling the myopic peripapillary crescent was visible in cortical sections processed for

292 The presence and size of optic disc crescents were also investigated as an index of retinal

293 However, crescents were also seen in WKY rats that were given Lew

294 80 +/- 2% of glomeruli at day 10, whereas no crescents were seen in Lewis rats.

295 s, classic wire loop lesions, and occasional crescents were seen only in kidneys from NZM2328.DR3(+)A

296 m the Zagros region of Iran (eastern Fertile Crescent), where some of the earliest evidence for farmi

297 sors differentiate rapidly to form a cardiac crescent, while limited morphogenesis takes place.

298 tein, the overall shape of which resembles a crescent with a head and a body domain, with a protein f

299 sulting in the formation of typical cellular crescents with periglomerular infiltrate, albeit without

300 mesticated in different parts of the Fertile Crescent, with genetic analyses detecting multiple domes