ライフサイエンスコーパス: critical concentration

1 entrating a sample about the poly(A)-ligand 'critical concentration'.

2 actin monomers with some deviations near the critical concentration.

3 tration of the globular aggregates exceeds a critical concentration.

4 n in filamentous mass and an increase in tau critical concentration.

5 e and MJD patients that is cytotoxic above a critical concentration.

6 fected neuroblastoma cells was toxic above a critical concentration.

7 no effect on pointed-end kinetics or on the critical concentration.

8 se of R177H actin but slightly decreases its critical concentration.

9 d causes cell death if it accumulates past a critical concentration.

10 evidence of a nucleation phase and without a critical concentration.

11 e ends that determine the value of the actin critical concentration.

12 f the ends by tropomodulin did not alter the critical concentration.

13 ation slowed, but there is also an effect on critical concentration.

14 of the bound nucleotide, albeit at a higher critical concentration.

15 on at lower concentrations without a defined critical concentration.

16 ant filament length, was visualized near the critical concentration.

17 ms of alpha-synuclein do not differ in their critical concentrations.

18 cin (CAP) using MGIT 960 and WHO-recommended critical concentrations.

19 ilaments exhibit cooperative assembly with a critical concentration?

20 The critical concentrations above which aggregation begins c

21 tion-elongation mechanism, but with an ~4 uM critical concentration, an order-of-magnitude higher tha

22 mutant actin exhibited a higher than normal critical concentration and a delayed nucleation.

23 The dependences of the steady-state critical concentration and average filament length of ac

24 phage lysis occurs when the holin reaches a critical concentration and nucleates to form rafts, anal

25 In agreement, Ca(2+) decreases SOD1 critical concentration and nucleation time during aggreg

26 R177H actin has an increased critical concentration and polymerizes with a greatly ex

27 is, the soft nanoactahedra crystallize at a critical concentration and possess continuous crystallin

28 leation phenomena; we obtained lower tubulin critical concentrations and shorter polymers with discod

29 ity to inactivate DNase I, increases actin's critical concentration, and greatly reduces its rate of

30 SipA binds directly to actin, decreases its critical concentration, and inhibits depolymerization of

31 established from filament dissociation rate, critical concentration, and mass-per-unit length measure

32 apid mixing when thrombin was added near the critical concentration, and mixing also affected the rat

33 tranded filaments and larger bundles above a critical concentration, and they hydrolyze GTP at a very

34 Vinblastine-induced polymerization shows a critical concentration, and, in the presence of GTP, two

35 Considering WHO-endorsed critical concentrations as reference, WGS had high accur

36 arbed end growth of filaments and lowers the critical concentration at the bacterial surface.

37 We show that growth rates and the critical concentration at the barbed end are intimately

38 s about the origins of the difference in the critical concentration at the two ends of actin filament

39 Critical concentrations at which the inner leaflet is di

40 centrations at least 10-fold below the usual critical concentration, at the expense of increased cata

41 the neutrophil concentration approaches the critical concentration, bacterial populations in contact

42 Median critical concentrations based on exposure to a combinati

43 , the simulations predict the existence of a critical concentration below which tH does not form nano

44 there is no evidence for assembly below the critical concentration, but there is an abrupt transitio

45 ells binds actin filaments and decreases the critical concentration (C(c)) for actin polymerization.

46 lizes the filament lattice and increases the critical concentration (C(c)) for assembly.

47 l to FtsZ concentration from 0.7 microm (the critical concentration (C(c))) to 3 microm.

48 The much higher values of the critical concentrations, C(a)*, for the disappearance of

49 n, and, in the presence of GTP, two distinct critical concentrations can be identified.

50 asurements of high length diffusivity at the critical concentration cannot be explained by fragmentat

51 as found to be a slower GTPase with a higher critical concentration (CC) compared to Escherichia coli

52 The concept of critical concentration (CC) is central to understanding

53 previously unreported temperature-dependent critical concentration (Cc) that resembles a solubility

54 points and World Health Organization interim critical concentrations (CCs) for categorizing clinical

55 s of equilibrium constants produce the sharp critical concentrations characteristic of cooperative po

56 ith a lag phase shorter than ATP-actin and a critical concentration close to zero.

57 degree, laminin-4, even well below their own critical concentration, co-aggregated with laminin-1, ev

58 it ice recrystallization inhibition (IRI) at critical concentrations comparable to those of many nati

59 Third, for HC-1, the antibody at a critical concentration completely suppressed viral repli

60 As expected for semirigid chains, the critical concentrations decrease sharply with increasing

61 e polymerization rate increases and the bulk critical concentration decreases with increasing tempera

62 Critical concentrations depended on the dose response mo

63 However, the critical concentration did increase when the tropomoduli

64 For side branching, the critical concentration drops proportionally to the squar

65 drops with increasing branching, because the critical concentration drops.

66 pesticide inputs, leading to environmentally critical concentrations during rain events.

67 The critical concentration established for levofloxacin and

68 lly undergo rapid treadmilling due to a high critical concentration, fast monomer dissociation, and r

69 isolates for 48 h with and without drugs at critical concentrations, followed by incubation with 10(

70 s at nanomolar concentration, well below the critical concentration for Abeta fibril formation in the

71 concentrations both below and above c*, the critical concentration for Abeta micelle formation.

72 Fesselin did not alter the critical concentration for actin but did increase the ra

73 n initiating amyloidogenesis by lowering the critical concentration for aggregation into the nanomola

74 olymerization defects, with a 40-fold higher critical concentration for assembly than WT SM alpha-act

75 vating the coat and effectively lowering its critical concentration for assembly.

76 minus ends, movement by treadmilling, and a critical concentration for assembly.

77 The measurements show that the lower critical concentration for cobalt hexammine as compared

78 FtsZ has to be at or above the critical concentration for copolymerization to occur, in

79 on but have a relatively minor effect on the critical concentration for fibril growth.

80 entration many orders of magnitude below the critical concentration for fibrillation in the bulk solu

81 aspects of actin polymerization, such as the critical concentration for filament formation and bulk g

82 * did not affect FtsZ GTPase activity or the critical concentration for FtsZ assembly but was able to

83 tion resulted in an increase in the apparent critical concentration for FtsZ assembly.

84 cooperative self-assembly model to obtain a critical concentration for lattice assembly.

85 Below the critical concentration for microtubule assembly and in t

86 microtubule nucleation, reduces the tubulin critical concentration for microtubule assembly, and sup

87 oupled for Elongator to decrease the tubulin critical concentration for microtubule elongation.

88 le growth constant, equal to Cr-1 (Cr is the critical concentration for microtubule formation), and K

89 formation and found that the drug raises the critical concentration for microtubule polymerization in

90 n did not reach CSF concentrations above the critical concentration for Mycobacterium tuberculosis.

91 AGE-B2 reduces G3BP protein levels below the critical concentration for phase separation and suppress

92 ntrinsic to the tubulin dimer and reduce its critical concentration for polymerization at 0 degrees C

93 pparent nanomolar affinity and increases the critical concentration for polymerization at the pointed

94 The critical concentration for polymerization obtained by th

95 sheets in the presence of calcium, and has a critical concentration for polymerization of 1.5 muM.

96 Saturating phosphate reduces the critical concentration for polymerization of Mg-ADP-acti

97 te of nucleotide exchange was increased, the critical concentration for polymerization was increased,

98 rties of pY53-actin, including its increased critical concentration for polymerization, reduced rates

99 cant fraction (~10%) of stable dimers at the critical concentration for polymerization, supporting a

100 ing a large pool of actin monomers above the critical concentration for polymerization.

101 ribution (Kd = 1.2 microM) and increases the critical concentration for polymerization.

102 to use the scale invariance to estimate the critical concentration for protein phase separation.

103 and this boundary is always larger than the critical concentration for the actin filament's growth a

104 derations when choosing the most appropriate critical concentration for use in public health guidance

105 hout Mg(2+), by significantly increasing the critical concentrations for assembly.

106 reen CEA in real samples and differentiating critical concentrations for establishing a diagnosis.

107 Further studies are needed to evaluate critical concentrations for ethambutol and streptomycin

108 ce as stiff as DNA, primarily because of low critical concentrations for first appearance of the anis

109 This review provides support for recommended critical concentrations for isoniazid and rifampin in co

110 gulation, which corroborates well with their critical concentrations for phase separation.

111 Critical concentrations for the isotropic to cholesteric

112 up to twofold while slightly decreasing the critical concentration from 0.23 microM to 0.18 microM.

113 essively as the concentration approaches the critical concentration from below.

114 To explain the effect of profilin on actin critical concentration in a manner consistent with therm

115 ound in cells, and the effect of profilin on critical concentration in cell extracts is demonstrated

116 perativity observed in FtsZ kinetics and the critical concentration in different buffer media.

117 When present above a critical concentration in pure solvent, asphaltene "mono

118 nism also predicts the effect of profilin on critical concentration in the presence of the limited am

119 in was added at concentrations far above the critical concentration in two clinical clotting assays f

120 perative self-assembly model that exhibits a critical concentration in vivo.

121 olchicine site ligand, and measuring tubulin critical concentrations in the presence of poorly solubl

122 t mass correlated strongly with decreases in critical concentration, indicating that both pseudophosp

123 ncreased nucleation rates, and submicromolar critical concentrations, indicating a final equilibrium

124 produce new nucleation sites, and the upper critical concentration is determined by the supersaturat

125 the presence of an analyte above or below a critical concentration is more informative for decision

126 When a critical concentration is reached, the alignment of nano

127 2+) (which allows FtsZ to hydrolyze GTP) the critical concentration is reduced 10-fold to approximate

128 At this critical concentration, it is calculated that a minimum

129 igin of enhancement of performance above the critical concentration lies in the slowing down of the c

130 ersus actin concentration yields an apparent critical concentration, like that seen for actin polymer

131 Critical concentration measurements confirmed that N744

132 L, while DALY-based guidance suggests lower critical concentrations might be warranted in some cases

133 Here, we theoretically derive the critical concentration nc for films of heavily doped nan

134 pH via a nucleation-growth mechanism, with a critical concentration near 1 mM.

135 ctin in T. gondii lacks both a lag phase and critical concentration, normally characteristic of actin

136 onic acid at the sn-2 position occurs when a critical concentration of 'seeding molecules' derived fr

137 (e.g., self-assembles to form micelles at a critical concentration of 0.1 mM in aqueous 0.1 M Li(2)S

138 A critical concentration of 0.4-1.0 microM was indicated b

139 the "aggregated" state begins to occur at a critical concentration of 1 AmB per 1000 lipids in the m

140 p isolates in MGIT960 media (WHO-recommended critical concentration of 1 mug/mL).

141 GTP-actin polymerizes with an apparent critical concentration of 1.5 microm, higher than that o

142 A critical concentration of 900 or 1,200 microg of PZA/ml

143 iviral activity of A3G in vivo may require a critical concentration of A3G in viral particles that wi

144 A critical concentration of about 0.8 microg/mL of 1 is fo

145 the conditions examined here, assembly has a critical concentration of about 1 muM.

146 even at concentrations much higher than the critical concentration of actin filaments, indicating th

147 if molecular crowding results in a very low critical concentration of actin in vivo.

148 In the presence of TPM, the apparent critical concentration of actin is 5.5 microm, 10-15-fol

149 amount of sequestered actin (by lowering the critical concentration of actin) and augments nucleation

150 vitro that TPM can significantly affect the critical concentration of actin.

151 eady state, F-actin depolymerizes toward the critical concentration of ADP-actin, our analysis indica

152 Our results show that once a small but critical concentration of amyloid fibrils has accumulate

153 ation between variant fitness scores and the critical concentration of amyloid formation.

154 We have used this equation to calculate the critical concentration of antigen-specific CD8+ T cells,

155 orylated cofilin, we estimate a mean G-actin critical concentration of approximately 0.45 microM and

156 ivity increases with concentration below the critical concentration of approximately 1 mg/ml for micr

157 similar to that of F-actin, however, with a critical concentration of approximately 3 nm, which is a

158 A22 increases the critical concentration of ATP-bound MreB assembly from 5

159 capping protein, tropomodulin, increases the critical concentration of barbed end capped actin, i.e.

160 Our model predicts a critical concentration of cardiolipin below which domain

161 Specifically, we find that above a critical concentration of defects, free-standing graphen

162 In bulk semiconductors, the critical concentration of electrons at the metal-insulat

163 For all polymerization processes, a critical concentration of free monomers, as defined by t

164 omplex, similar in magnitude to the 0.72 muM critical concentration of FtsZ protofilament assembly at

165 Moreover, the critical concentration of FtsZ required for ring formati

166 SipA lowers the critical concentration of G-actin, stabilizes F-actin at

167 olymerization was evaluated by measuring the critical concentration of GDP-tubulin in the presence of

168 ignificant extent, but it also decreases the critical concentration of gelator needed to form stable

169 ences associated with measured values of the critical concentration of incubation solution.

170 A thermally-driven critical concentration of isotropic Tb ions triggers the

171 The critical concentration of LOOH reverse micelles showed s

172 l prior observation that profilin lowers the critical concentration of Mg2+-actin.

173 lent molecules (gel phase) are produced at a critical concentration of monomers.

174 Below a critical concentration of neutrophils, bacteria growth w

175 nding required both liposome formation and a critical concentration of phospholipid containing phosph

176 l nociceptive response thresholds requires a critical concentration of PLCbeta1 protein, its particip

177 Cbeta1 to thermal pain thresholds requires a critical concentration of PLCbeta1 protein.

178 After determination of the critical concentration of polymeric beads required to se

179 K113E actin exhibits a critical concentration of polymerization 4 times higher

180 ed, and there is a 3-4 fold reduction in the critical concentration of polymerization.

181 ect was observed on FtsZ GTPase activity and critical concentration of polymerization.

182 heterodimers--spontaneously assemble above a critical concentration of tetravalent spermine and are s

183 ion, HDL containing apoA-I, or at least some critical concentration of the antiatherogenic lipoprotei

184 At the critical concentration of the barbed end, c(crit), we fi

185 A critical concentration of the beta subunit may be requir

186 fore virion production, perhaps lowering the critical concentration of the chimeric protein required

187 rnal scaffolding protein may be to lower the critical concentration of the external scaffolding prote

188 spectroscopy to quantify , which is also the critical concentration of the isotropic-nematic transiti

189 We find that the critical concentration of the isotropic-nematic transiti

190 on in spindle architecture was observed at a critical concentration of the Kinesin-5 sliding motor.

191 of human blood plasma required addition of a critical concentration of thrombin.

192 bulin in the presence of TMAO and lowers the critical concentration of tubulin needed for assembly.

193 Cryptophycin did not alter the critical concentration of tubulin required for polymeriz

194 Beyond a critical concentration of ~1 atom %, boron and sulfur do

195 d A549 lung epithelial cells were exposed to critical concentrations of 0.1 and 0.5 ppm for 3 days.

196 mean for multiple fixtures and single sample critical concentrations of 1.02 x 10(5), 8.59 x 10(5), a

197 on propagation and neurotoxicity relating to critical concentrations of alternate PrP isoforms whose

198 formation of transcriptional condensates at critical concentrations of cell type-specific regulators

199 We propose that the accumulation of critical concentrations of lipid peroxidation adducts du

200 Further studies to develop critical concentrations of other drugs for this low-pH m

201 Critical concentrations of phosphates that could inhibit

202 ts monomer-to-polymer assembly reaction, the critical concentrations of that reaction, the manner in

203 uantitative differences were measured in the critical concentrations of the complexes required for as

204 k values in order to calculate corresponding critical concentrations on a per-fixture and aggregate (

205 and assembly but fails to reduce the tubulin critical concentration or suppress dynamic instability;

206 At critical concentration or temperature, the bandgap colla

207 gene sequencing overcame the limitations of critical concentration phenotyping, probe-based genotypi

208 Upon reaching a critical concentration, QSMs induce transcriptional alte

209 rug susceptibility testing (DST) at a single critical concentration, quantifies drug resistance.

210 e differences in the barbed- and pointed-end critical concentrations, rapid subunit dissociation from

211 Allele-specific effects were also seen on critical concentration, rate of depolymerization, and fi

212 ration (1.9 vs. 1.4 mg/L), and critical dose/critical concentration ratio (0.52 vs. 2.2).

213 population density, and when this reaches a critical concentration, reflecting a bacterial quorum, s

214 n situ than in the wild type and has a lower critical concentration, reflecting altered nucleation pr

215 decrease in the probability of reaching the critical concentration required for a nucleation event a

216 s and PRC1 act synergistically, reducing the critical concentration required for condensation by more

217 Critical concentration required for deoxy Hb S beta87 Th

218 At concentrations of drug lower than the critical concentration required for Raf-1 activation, p5

219 yloidogenic polypeptide in vivo is below the critical concentration required to form the aggregates o

220 We find that above a critical concentration, swimmers form a long lived crowd

221 zes in the presence of ATP but with a higher critical concentration than in the absence of ATP and fo

222 pparently cooperative process, with a higher critical concentration than values reported for other Ft

223 enzyme-catalyzed lipid hydrolysis reaching a critical concentration that allows the enzyme to react a

224 CT1) rapidly polymerized into filaments at a critical concentration that was 3-4-fold lower than conv

225 further show that polymerization requires a critical concentration that we propose is only achieved

226 rfactants is observed, but once it reaches a critical concentration the assembler starts to produce p

227 Interestingly, above a critical concentration, the addition of palmitic, steari

228 he initial stage; once the oligomers reach a critical concentration, the blackberry formation process

229 sorb onto the lipid membranes, and then at a critical concentration, the peptides begin to aggregate

230 ensates and activates cell identity genes at critical concentration thresholds achieved during smooth

231 -dependent conductivity on both sides of the critical concentration, thus establishing the quantum-cr

232 the master regulator Spo0A, which rises to a critical concentration to initiate sporulation.

233 P(i)-actin (low critical concentration) to ADP-actin (high critical conc

234 moderate differences between the ATP and ADP critical concentrations, treadmilling may occur, but we

235 ibril elongation thermodynamics derived from critical concentration values for fibril growth.

236 Critical concentration values of wild-type and mutant pr

237 The increase in apparent critical concentration was always less than the total am

238 ster than wild-type (WT) actin, although the critical concentration was not affected.

239 mers' interaction with the bilayer below the critical concentrations was also found.

240 ce of interaction with the bilayer below the critical concentrations was observed for the 11Bz polyme

241 ine mutations with MICs overlapping with the critical concentration were excluded.

242 Three critical concentrations were determined; stimulation sta

243 ns in system recovery, and the corresponding critical concentrations were generally between 5 and 15

244 rent insulator compound is doped beyond some critical concentration; what exactly happens at this sup

245 y forms monodisperse nanotubes (NTs) above a critical concentration when solubilized in pure water.

246 w critical concentration) to ADP-actin (high critical concentration) when 70-98% of the ends are capp

247 ible reactions are characterized by a pseudo-critical concentration, whereas irreversible reactions c

248 FtsZ-GTP without Mg(2+) exhibits an apparent critical concentration, which is indicative of cooperati

249 oupling is increased to about 0.6 around the critical concentration, which is sufficient to induce ph

250 ets of sizeable dimensions already below the critical concentration, which is the concentration at wh

251 titatively assessed through determination of critical concentrations, which can be used to obtain the

252 rt, from an apparent lowering of the tubulin critical concentration with drug combinations compared w

253 Single sample critical concentrations with a per-exposure-corrected DA