ライフサイエンスコーパス: critically

1 rom which they are extracted is investigated critically.

2 prevent the development of the disease, and critically, a subset of asthmatics are resistant to ster

3 Critically, across days the world also appeared signific

4 Together, the immune system critically acts as a rheostat that fine-tunes the balanc

5 We critically address the features, reaction selectivity, s

6 Its thermal conductivity critically affects Earth's thermal structure, evolution,

7 Here, we critically analyze recent advances in computational hete

8 cial to evaluate the accuracy of such models critically and systematically.

9 ral readership, to understand, interpret and critically appraise the quality of clinical trial design

10 Few studies critically assess implications of analytic choices made

11 We critically assess the ability of these five brain modes

12 es-Opportunities-Threats (SWOT) framework to critically assess the current status of this rapidly evo

13 In this Review, we critically assess the potential trajectory of this line

14 We critically assess the role of various signalling agents

15 ies exploring potential applications will be critically assessed and the remaining challenges for the

16 Zr atomic ratio and the lattice parameter is critically assessed: it is found that recent studies rep

17 nduced hypercytokinemia and inflammation are critically associated with COVID-19 severity.

18 Critically, both combustible tobacco products and e-ciga

19 More critically, cashew allergy is frequently associated with

20 in lesions while still requiring the user to critically consider other possible diagnoses.

21 diverse functions in metabolism and immunity-critically contribute to thymic integrity and function.

22 The GPCR-betaarr interaction critically contributes to GPCR desensitization, endocyto

23 t of ATP5G1 from a mammalian hibernator that critically contributes to intrinsic cytoprotection again

24 sociated X apoptosis regulator (BAX) protein critically contributes to this process by forming pores

25 pathway, and disorders within pathways that critically control autophagy through monitoring of the s

26 ls that endothelial identity and function is critically controlled by the histone demethylase JMJD2B,

27 Both cell extension and retraction critically depend on the organization and dynamics of th

28 Recovery from coma might critically depend on the structural and functional integ

29 The overall process is critically dependent on a complex interplay between the

30 ndergo homeostatic proliferation and are not critically dependent on IL-15 for their maintenance.

31 effects of these repopulating microglia are critically dependent on interleukin-6 (IL-6) trans-signa

32 Endocytosis is critically dependent on intracellular Ca(2+), and the ac

33 The function of TTBK2 in ciliogenesis is critically dependent on its kinase activity; however, th

34 aptations in brain function and behavior are critically dependent on the pattern of drug administrati

35 T cell expansion and differentiation are critically dependent on the transcription factor c-Myc (

36 ropellants, explosives, and pyrotechnics) is critically dependent on their microstructure.

37 selectively in BMMC, the production of IL-9 critically depends on autocrine IL-3 acting via the sust

38 The time evolution of those responses critically depends on distinct shifts in the regional at

39 Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens

40 The success of these methods critically depends on the identification of eQTLs, which

41 a cancer model (under continuous treatment) critically depends on the initial spatial configuration

42 Kidney homeostasis is critically determined by the coordinated activity of the

43 ated approaches from a design perspective is critically developed.

44 l food to a stranger (Experiment 1) and more critically, did so after an experimental manipulation th

45 ontinually growing use of glyphosate and its critically discussed health and biodiversity risks ask f

46 nd the disadvantages of the technologies are critically discussed.

47 encapsulation of therapeutic compounds, and critically discusses the limitations and future perspect

48 Critically, disruption of GAL5.1 in mice using CRISPR ge

49 ead to an immediate change in IUCN status to Critically Endangered due to small population sizes and

50 We found that 7.1% of the taxa may be critically endangered in their natural habitats, 50% may

51 In this review, we critically evaluate how postnatal ELS relates to abnorma

52 In this review, we critically evaluate these factors and provide guidance f

53 ration efficiency of each technique has been critically evaluated and compared.

54 This systematic review identifies and critically evaluates the mechanistic and clinical eviden

55 In this article, we critically examine the available data on the risk of tra

56 The aim of this review was to critically examine the behavioral and neuroimaging liter

57 We critically examine the pipeline of SLE drugs, including

58 existing guidelines published after 2010 and critically examine their recommendations to see how they

59 Here, we critically examine this approach across three distinct d

60 icipation from remote or distal positions is critically examined, and alternative hypotheses for the

61 roaden their food packaging applications are critically examined.

62 d with a reduction in acute kidney injury in critically ill adults (odds ratio, 0.47; 95% CI, 0.34-0.

63 ve care units (ICUs), we enrolled conscious, critically ill adults who had a tracheostomy tube; patie

64 conducted a multicenter cohort study of 3099 critically ill adults with COVID-19 admitted to intensiv

65 high-flow nasal cannula after extubation in critically ill adults.

66 valuate the prevalence of rehabilitation for critically ill children and associated barriers.

67 Critically ill children are frequently exposed to noninv

68 In critically ill children, NMR metabolomics differentiates

69 ypothesized that in a heterogeneous group of critically ill children, there would be different metabo

70 Delirium occurs frequently in critically ill children, with highest rates reported in

71 spectra were acquired in plasma samples from critically ill children.

72 sely associated with short-term mortality in critically ill cirrhotic patients.

73 Findings were similar in the surgical and critically ill cohorts.

74 characteristics, treatment, and outcomes of critically ill coronavirus disease 2019 (COVID-19) solid

75 One-hundred nine critically ill coronavirus disease 2019 patients admitte

76 nt of meeting current and projected needs of critically ill coronavirus disease 2019 patients.

77 We found a high incidence of CAPA among critically ill COVID-19 patients and that its occurrence

78 To overcome the surge of critically ill COVID-19 patients, reallocating health ca

79 ectively investigating treatment tailored to critically ill hemophagocytic lymphohistiocytosis patien

80 ve bacterial pathogen that primarily infects critically ill individuals.

81 or rIFN-beta1a) therapy was commonly used in critically ill MERS patients but was not associated with

82 Across 11 studies, compared with critically ill nonseptic, septic patients had significan

83 Survival in critically ill oncology and hematology patients with sep

84 gs attention to the respiratory drive of the critically ill patient.

85 m 53% in mild-to-moderate patients to 88% in critically ill patients (p=0.036).

86 phalopathy severity by Glasgow Coma Scale in critically ill patients (rho, -0.54; p = 0.036).

87 ependently predicts in-hospital mortality in critically ill patients across the glycemic spectrum.

88 ied in serum from 321 prospectively enrolled critically ill patients and compared with clinical outco

89 ghlighted other important considerations for critically ill patients and evaluated interventions to r

90 lternative complement pathway in a series of critically ill patients and in a mouse pneumonia model.M

91 ctives: To determine if clinical outcomes of critically ill patients are predicted by features of the

92 strategies that improve clinical outcomes of critically ill patients boarded in the emergency departm

93 Rehabilitation interventions in critically ill patients do not influence mortality and a

94 Recent research in critically ill patients has highlighted other important

95 oninferiority trial designs and exclusion of critically ill patients in many trials.

96 sts its possible role in the routine care of critically ill patients in the future.

97 P tool may be used in the future to stratify critically ill patients in the ICU according to their im

98 Uses of ketamine discussed focused on critically ill patients in the ICU and emergency departm

99 ture of COVID-19 and the large population of critically ill patients included in these analyses, the

100 benefit in several disease states impacting critically ill patients including pain, alcohol withdraw

101 aims at showing that anxiety at admission in critically ill patients is associated with new organ fai

102 the prevalence of venous thromboembolism in critically ill patients receiving different regimens of

103 Its incidence and outcome in critically ill patients remain, however, largely unknown

104 Almost 10% of these critically ill patients subsequently die.

105 100% occurrence of venous thromboembolism in critically ill patients supported by venovenous extracor

106 or of TimeSignature was higher in individual critically ill patients than healthy patients (4.90 vs 1

107 pecific clinical characteristics of infected critically ill patients that mediate the associated path

108 ranging from the morbidity and mortality of critically ill patients to the diagnosis and prognosis o

109 egy on organ injury are less well studied in critically ill patients treated with continuous kidney r

110 Mortality among these critically ill patients was high.

111 n.Measurements and Main Results: Lungs of 91 critically ill patients were sampled using miniature BAL

112 We reviewed thromboelastography studies in critically ill patients with coronavirus disease 2019 to

113 In this cohort of critically ill patients with coronavirus disease 2019, n

114 he cytokine milieu in the lungs and blood of critically ill patients with COVID-19 acute respiratory

115 AKI-RRT is common among critically ill patients with COVID-19 and is associated

116 Care) genome-wide association study in 2,244 critically ill patients with COVID-19 from 208 UK intens

117 authors report brain imaging features in 11 critically ill patients with COVID-19 with persistently

118 nthetic glucocorticoid, enhanced survival of critically ill patients with COVID-19.

119 irement were similar between SOT and non-SOT critically ill patients with COVID-19.

120 This is a retrospective cohort study of critically ill patients with laboratory-confirmed MERS f

121 rferon (RBV/rIFN) therapy on the outcomes of critically ill patients with Middle East respiratory syn

122 the most challenging problems in the care of critically ill patients with oliguric acute kidney injur

123 Critically ill patients with sepsis or septic shock are

124 o bring precision medicine to the bedside of critically ill patients with sepsis.

125 ,658 (Adjunctive Corticosteroid Treatment in Critically Ill Patients with Septic Shock) and $30,911 (

126 hypotension during vasopressor support among critically ill patients with shock and to determine whet

127 on and adverse kidney-related outcomes among critically ill patients with shock.Objectives: To invest

128 r positive end-expiratory pressure (PEEP) in critically ill patients without acute respiratory distre

129 Compared with critically ill patients without major organ disease, pat

130 myocardial injury from the infection (22% of critically ill patients).

131 ll patients, very specific subpopulations of critically ill patients, and on early goal-directed ther

132 entral venous catheters, are often needed in critically ill patients, but also are associated with co

133 s are preparing for the anticipated surge in critically ill patients, but few are wholly equipped to

134 We studied 112 critically ill patients, including 53 with sepsis and 59

135 We studied 112 critically ill patients, including 53 with sepsis and 59

136 to address emergency department boarding of critically ill patients, including emergency department-

137 among patients with ESKD compared with other critically ill patients, including those with diseases o

138 onale: Recent studies have revealed that, in critically ill patients, lung microbiota are altered and

139 In critically ill patients, we showed that mitophagy was in

140 with hypoxia and hemodynamic instability in critically ill patients.

141 should be not used to track contractility in critically ill patients.

142 nary artery occlusion pressure in ventilated critically ill patients.

143 quently required for mechanically ventilated critically ill patients.

144 e of admission to the intensive care unit in critically ill patients.

145 and safe assessing thromboembolic disease in critically ill patients.

146 ctability in extubation failure detection in critically ill patients.

147 ten results in significant fluid overload in critically ill patients.

148 ate that is both common and consequential in critically ill patients.

149 e measure of the central circadian rhythm in critically ill patients.

150 N ratio correlated with improved outcome for critically ill patients.

151 gut-associated bacteria) predict outcomes in critically ill patients.

152 of epinephrine administration on outcome of critically ill patients.

153 Hyperferritinemia is frequently seen in critically ill patients.

154 tensive care unit, with a proven benefit for critically ill patients.

155 the pathophysiology of respiratory drive in critically ill patients.

156 s, our institution prepared for an influx of critically ill patients.

157 med for prolonged endotracheal intubation in critically ill patients.

158 Consecutive endotracheal intubations in critically ill patients.

159 help expand the donor pool in this subset of critically ill patients.

160 amples from a cohort of septic and nonseptic critically ill patients.

161 n MRI at the point of care, particularly for critically ill patients.

162 lues, the features more commonly observed in critically ill patients.(C) RSNA, 2020.

163 RTICIPANTS: Descriptive feasibility study of critically ill pediatric patients with suspected monogen

164 with previous descriptions of endotypes in a critically ill population with acute respiratory distres

165 umatic stress disorder were similar to other critically ill populations and were related to physical

166 with matched hospital controls, costs of the critically ill remained higher throughout the follow-up.

167 Critically ill surgical patients may receive concomitant

168 Concomitant aspirin and anticoagulation in critically ill surgical patients was associated with an

169 Among critically ill surgical sepsis patients, persistent AKI

170 1,267 serum and respiratory samples from 719 critically ill UK patients with COVID-19 and suspected p

171 400 hospital-admitted COVID-19 patients (144 critically ill) primarily receiving standard-dose prophy

172 on for gram-negative HABP/VABP, including in critically ill, high-risk patients.

173 tracorporeal membrane oxygenation to support critically ill, poisoned patients in the United States i

174 In the critically ill, radiographically confirmed VTE and major

175 -confirmed COVID-19, of which 257 (22%) were critically ill.

176 69.6% were kidney recipients, and 25.0% were critically ill.

177 undergoing cardiac surgery, and 692 who were critically ill.

178 nly in a fraction of patients as they became critically ill.

179 ccurate national-scale corn yield prediction critically impacts mercantile markets through providing

180 efrontal cortical-striatal circuits-pathways critically implicated in goal-directed decision-making.

181 helper (Tfh)-cell induction, a T-cell subset critically implicated in lymphoid organ formation, in CO

182 User burnout may not be critically important as long as the first parts of a sch

183 ility and crystallinity of the material--two critically important factors for crystalline lattice sel

184 and optimizing resource allocation are both critically important for achieving robust system functio

185 rganization of cytoplasm in zygotic cells is critically important for establishing the body plans of

186 Although angiogenesis is critically important for normal tissue regeneration, it

187 mixtures of large saturated hydrocarbons is critically important for numerous fields, including petr

188 piratory network, which, during eupnoea, are critically important for respiratory phase transition an

189 gle-stranded tails and that the KH domain is critically important for sequence specificity and unwind

190 een active-site and exosite contributions is critically important for the specificity of many proteas

191 The capture and use of water are critically important in drylands, which collectively con

192 oxide (NO) in physiological environments is critically important in monitoring neurotransmission, in

193 Mean arterial pressure is critically important in patients with cirrhosis in the I

194 ) and toxic industrial chemicals (TICs), are critically important in the modern age due to continuous

195 Adventitious root (AR) formation is critically important in vegetative propagation through c

196 First, the critically important molecular descriptors were validate

197 The microtubule cytoskeleton plays critically important roles in numerous cellular function

198 stuzumab, and bevacizumab biosimilars, it is critically important that clinicians understand how the

199 Our data demonstrate that it is critically important to prevent confounding bovine serum

200 Therefore, it is critically important to understand the needs of caregive

201 ynuclein oligomers reported in this study is critically important to understand the toxicity of these

202 Such efforts, although critically important, are locally constrained.

203 The chaperone is also critically important, however, to the pathogen's human h

204 Critically, in the absence of STX3, OS proteins such as

205 t root responses to precipitation change may critically influence root productivity and soil carbon d

206 properties of the extracellular matrix (ECM) critically influence tumor progression, but the molecula

207 tabolic derangement due to advanced shock in critically injured patients leads to the pulmonary seque

208 y not only physically anchor cells, but also critically integrate signaling between the extracellular

209 This impairment appeared to critically involve inhibitory neurons in the auditory co

210 ates that glucagon secreting alpha cells are critically involved in disease progression and proper gl

211 dala and prefrontal cortex, brain structures critically involved in fear extinction and regulation of

212 of the Wnt/beta-catenin signaling pathway is critically involved in gastric cancer (GC) progression.

213 ard-seeking and associative learning and are critically involved in reinstatement of psychostimulant-

214 ns in the external globus pallidus (GPe) are critically involved in the motor deficits of dopamine-de

215 formation and function and, as such, may be critically involved in the pathogenesis of neurodevelopm

216 Our findings show that T(FH)17 cells are critically involved in the pathogenesis of pemphigus and

217 thalamo-lateral amygdala (T-LA) synapses is critically involved in the regulation of cocaine-cue mem

218 by targeting two proteins, srGAP3 and Rac1, critically involved in the regulation of the actin cytos

219 belongs to the IL-10 cytokine family, and is critically involved in tissue regeneration.

220 further due to a thromboinflammatory process critically involving platelets and T cells, but the unde

221 of protein antigen and nucleic acid ligands critically limit the clinical development of these const

222 Critically, management can provide substantial conservat

223 subset of schizophrenia-associated proteins critically modified by glycosylation including glutamate

224 of neonatal mice; through these effects they critically modulate the organization of hypothalamic fee

225 t target the precise needs of patients are a critically needed and expanding market.

226 placental transport to maintain delivery of critically needed FA.

227 BACKGROUNDNovel therapeutic approaches are critically needed for Staphylococcus aureus bloodstream

228 New therapeutics are critically needed to counter the sources of periodontal

229 vernance informed by behavioural research is critically needed to empower individuals online.

230 Enhanced vaccination efforts are critically needed, particularly targeting adults at high

231 ents that selectively target this cancer are critically needed.

232 determine infection and vaccine efficacy is critically needed.

233 and objective, imaging-based biomarkers are critically needed.

234 Critically, network interactions have not been considere

235 Critically, neutrophils were able to kill larvae in vitr

236 ppropriate seromonitoring age groups depends critically on age-dependent exposure patterns.

237 entity, the success of spillovers can depend critically on disrupting the link between identity and t

238 is approach shows that transcription depends critically on dynamic crowding as the gene expression re

239 , being more data efficient and relying more critically on eye-movements.

240 The accumulation of these cells depends critically on interleukin (IL)-33 produced by local mese

241 article-borne drugs targeting tumors depends critically on nanoparticle design.

242 t transcription factor dependencies, relying critically on Otx2.

243 ing of their structure and evolution depends critically on our ability to model such matter.

244 electrical properties are thought to depend critically on the covalency of the metal-ligand bond, an

245 uires highly specific dynamics, which depend critically on the details of how amino acids are packed.

246 posit that episodic memory formation depends critically on the hippocampus, which binds features of a

247 intrinsic analytical strength of ECL depends critically on the overall efficiency of the mechanisms o

248 e future evolution of forest biomass depends critically on the response of tree longevity and growth

249 Critically, only high-level models shared vERP variabili

250 Critically, our results indicate that models learned thr

251 Critically, our work suggests that adaptive myelination

252 and synthetic thermoresponsive hydrogels are critically presented.

253 past and may potentially occur at present in critically pressurized reservoirs.

254 Critically, pupil dilation to CS(+) was correlated with

255 ether mGluR5 might act downstream of BDNF to critically regulate VMH neuronal activity and metabolic

256 s (BNST) is a sexually dimorphic region that critically regulates negative affective- and stress-indu

257 nds developing excitatory synapses, where it critically regulates synapse formation and the resulting

258 Cortical computations are critically reliant on their local circuit, GABAergic cel

259 Accordingly, API development critically relies on characterizing and quantifying the

260 rovement of bioinformatics predictors, which critically relies on the availability of large amounts o

261 the glacial Southern Ocean, Fe fertilization critically relies on the dynamic interaction of changes

262 nctioning and high-order cognitive functions critically rely on glucose as a metabolic substrate.

263 Thus, TNBC cells critically rely on IRE1alpha to adapt their ER to in viv

264 nal analysis uncovers the TM1 region of Mgr2 critically required for association with Tim23 and Tim21

265 ine, combined with targeted chemotherapy, is critically required for eliminating LF worldwide.

266 e show that the transcription factor ETS1 is critically required for human NK cell differentiation.

267 I/SNF complex components as the factors most critically required for response to two classes of estro

268 Here, we critically review how the field is rapidly evolving in r

269 We critically review in depth newly developed biosensing me

270 in understanding among clinicians on how to critically review observational studies that have incorp

271 In this paper, we will critically review our current knowledge of the secondary

272 We critically reviewed 32 studies on Medicaid managed care

273 Potassium metal anodes are then critically reviewed, emphasizing electrolyte reactions t

274 lesion inference and network approaches, we critically revisit and update the original theoretical n

275 in HBECs near senescence when telomeres are critically short.

276 Critically, similar to task-evoked activations, spontane

277 rates a transient I(II) intermediate that is critically stabilized by added acetate ions.

278 pore pressure changes initiate seismicity on critically stressed faults and Coulomb static stress tra

279 Critically, supplementation with extra wild-type Prph2 p

280 nique chemical and physical properties often critically support biological processes.

281 there it is used in fatty acid synthesis to critically support embryonic development.

282 example, the ventral and dorsal CA1 regions critically support social and spatial discrimination, re

283 Critically, targeting this signaling exclusively in astr

284 entological analysis represents a gateway to critically test the paleoenvironmental models describing

285 research as a lens through which to evaluate critically the available evidence to support these key s

286 Critically, the gated generation of a fluorescent produc

287 Critically, the moment participants provided their confi

288 Critically, the protective allele of the strongest AMD-a

289 Critically, the visual noise changed dynamically over ti

290 Critically, this error signal emerges in visual associat

291 Critically, this hypothesis is independently supported b

292 Critically, this model simultaneously reproduces the sol

293 Critically, this was validated in patient-derived explan

294 adaptation toward external aggressions, most critically to colonizing microorganisms, among other fun

295 Ubiquitin mediated signaling contributes critically to host cell defenses during pathogen infecti

296 (outpatients [n=178]), inpatients [n=12] and critically unwell patients admitted to the intensive car

297 These initially innate behaviors depend critically upon coordinated development of the mouth, to

298 evelopment for psychiatric disorders depends critically upon the development of physiological measure

299 Critically, we manipulated the benefactor's intention to

300 Critically, we observe a shift from growth being control