ライフサイエンスコーパス: cross-species

1 onments, it may restrict a virus' ability to cross species.

2 ugh the type I IFNs generally do not display cross-species activities, rmIFN exhibited high antiviral

3 inogalactan and Pel, that they might display cross-species activity.

4 Cross-species alignment of this cell cluster with a well

5 and short-range attraction to noni, and our cross-species allele-transfer experiments demonstrate th

6 h data from external sources and facilitates cross-species analyses based on orthology.

7 f RTT and highlight the potential benefit of cross-species analyses in identifying potential disease-

8 Functionality-wise cross-species analyses now enable users to analyse expre

9 essential data for connectomics analyses and cross-species analyses of connectomes and brain connecti

10 ibute to a connectomics database, to further cross-species analyses of connectomes and illuminate wir

11 Cross-species analyses revealed a PTEN gene signature th

12 Cross-species analyses show the efficiency of the screen

13 By performing a mouse-human cross species analysis between the TAp63 metastatic mamm

14 te to a connectomics database, to facilitate cross species analysis of brain connectomes and wiring p

15 iolet radiation-driven mouse cuSCC model for cross-species analysis and demonstrate that cuSCC bears

16 Here we perform a cross-species analysis by sequencing tumor-germline pair

17 They thus emphasize the utility of cross-species analysis for understanding the predictors

18 A cross-species analysis identifies a highly conserved seq

19 Cross-species analysis of RNA editing in several tissues

20 es in individual vertebrates, our integrated cross-species analysis provides valuable insights into t

21 of other settings and data types, including cross-species analysis, single-nucleus DNA methylation,

22 The database is cross-species and cross-technique and it covers metaboli

23 ing enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of SARS-C

24 ing enzyme 2 (ACE2), which regulate both the cross-species and human-to-human transmissions of SARS-C

25 The results of our cross-species and integrated approach provide insights i

26 To address this, we evaluated cross-species and post-duplication sequence and expressi

27 o resolve infection and leave a cross-stage, cross-species, and lasting immunity.

28 nd E. cloacae, indicating its potential as a cross-species antibacterial agent.

29 In this study, we tested the cross-species application of the Affymetrix 600K Chicken

30 Our study provided evidence for successful cross-species application of the chicken SNP array in gr

31 Here, we performed a cross-species approach by applying a mouse whole-genome

32 This cross-species approach identified unanticipated regulato

33 we examined the fecal microbiome by using a cross-species approach in both rat and human studies of

34 Here, we use a multi-day cross-species approach in humans and mice to report the

35 A cross-species approach involving zebrafish and mammalian

36 resonance imaging (fMRI), suggesting that a cross-species approach targeting this mechanism might be

37 Using a cross-species approach, we first investigated the relati

38 Here, implementing a cross-species approach, we investigated the association

39 Here, using a cross-species approach, we tested the role of Nr4a1 and

40 ying aggression, we undertook an integrated, cross-species approach.

41 nd highlight the challenge and power of such cross-species approaches in informing the 'next steps' t

42 ies (e.g. CRISPR) and support of integrated, cross-species approaches to uncovering gene function usi

43 Cross-species assessment of upper/fore- limb and lower/h

44 To harmonize cross-species assessments, we used a combination of two

45 specific mechanisms may be needed to explain cross-species attachment and socio-cognitive abilities.

46 Certain RNA viruses can cross species barriers and cause disease in new hosts.

47 t different levels of pH, the virus can only cross species barriers if HA undergoes mutations that st

48 pt to new environments and are well known to cross species barriers.

49 vidence that these viruses have potential to cross species barriers.

50 We propose a cross-species bi-clustering approach which first denoise

51 active antibodies were eluted and tested for cross-species binding and reactivity to single-antigen H

52 gainst each targeted virus exhibited limited cross-species binding and, to a lesser extent, cross-neu

53 f endophyte and host plant imply a symbiotic cross-species biosynthesis pathway for astin C derivativ

54 h point of their critique by controlling for cross-species body size variation using body weights for

55 ssessing the efficacy of novel VAR2CSA-based cross-species boosting regimens.

56 r the next human virus, or which viruses can cross species boundaries.

57 tes; the pluripotential methyl-CpH signature crosses species boundaries and is distinct from neuronal

58 explore the combination of deep learning and cross-species chromatin accessibility profiling to build

59 trate that this innovative system allows for cross-species co-culture as well as long-term culturing

60 Developing cross-species collaborations will provide a wealth of re

61 ell and/or cell-to-tissue communications and cross-species communication.

62 ew perspectives on evolutionary processes in cross-species comparative analyses and assist in efforts

63 A cross-species comparative analysis of recurrent copy num

64 Our cross-species comparative genomic analysis provides uniq

65 Cross-species comparative oncogenomics, identifying driv

66 and peptidome of human EECs and to provide a cross-species comparison between humans and mice.

67 owed how integrating CRISPR-Cas9 system with cross-species comparison can help to uncover the functio

68 A cross-species comparison of open chromatin during preimp

69 Cross-species comparison of proteomes revealed higher mo

70 d reciprocal BLAST, we conducted a fly-human cross-species comparison of the phosphoinositide-3-kinas

71 Cross-species comparison shows that core network nodes a

72 tion and myelination that were validated via cross-species comparison to Ts65Dn trisomy mice.

73 A bioinformatic cross-species comparison using a gene expression signatu

74 Cross-species comparison was performed using the alcohol

75 tidomic profiles of human and mouse EECs and cross-species comparison will be valuable tools for drug

76 y expressed miRNA were further assessed by a cross-species comparison with human osteoblasts and OS c

77 Cross-species comparison within a single MSY phylogeny e

78 By launching a cross-species comparison, we unveiled a conserved transc

79 Cross-species comparisons allow for the identification o

80 nhuman animals on cognitive tasks complicate cross-species comparisons and interpreting results on th

81 Finally, cross-species comparisons between Ciona and the mouse ev

82 Cross-species comparisons of genomes, transcriptomes and

83 n the motor hierarchy.SIGNIFICANCE STATEMENT Cross-species comparisons of motor system organization c

84 Cross-species comparisons of recent selective sweeps can

85 Importantly, the different cross-species comparisons showed varying sensitivities t

86 analysis of the human data, supplemented by cross-species comparisons to macaques, indicated that CT

87 Using single-cell RNA sequencing and cross-species comparisons with mouse, cynomolgus monkey

88 In cross-species comparisons, the results obtained by diffe

89 ss species, making them reliable targets for cross-species comparisons.

90 defined and therefore remain problematic for cross-species comparisons.

91 Cross-species complementation assays demonstrated that E

92 Cross-species complementation assays showed that CeGRS1

93 nd plants evolved, phylogenetic analyses and cross-species complementation assays were performed.

94 in essentiality, these genes were capable of cross-species complementation, demonstrating that trans-

95 iota modulate the host signaling and broadly cross-species consequences.

96 We observed stronger cross-species conservation of regulatory elements in inh

97 We further present evidence for cross-species conservation of sensory projections to cen

98 for some Hsa21-orthologous genes, indicating cross-species conservation of this phenomenon.

99 the CBC:HapX complex shows promoter-specific cross-species conservation rather than regulon-specific

100 is a micropeptide that shows relatively weak cross-species conservation.

101 ss TCF4 and NRP1 Nevertheless, despite these cross-species conserved subset-specific transcripts, por

102 rical cognition, inasmuch as it bolsters the cross-species continuity of the biological system for nu

103 domain [NTD], amino acids [aa] 23 to 90) in cross-species conversion by comparing the conversion eff

104 NA-treated mice was confirmed by significant cross-species correlation of changes in MDD-associated g

105 highlight the value of the AOP framework for cross-species data integration.

106 supported by ADHD-relevant phenotypes in the cross-species database.

107 Cross-species deployment of lamprey elements identifies

108 Cross-species differences in leaf-wide growth determine

109 Cross-species disease transmission between wildlife, dom

110 and ecological end points, (3) facilitating cross-species dose-response evaluation, and (4) highligh

111 ine to produce a high yield of exosomes with cross-species efficacy.

112 lus are recognized in S. pombe, resulting in cross-species establishment of CENP-A(Cnp1) chromatin an

113 s of heteroplasmy, we describe an integrated cross-species evaluation of heteroplasmy in mammals that

114 be mentally simulated, providing converging cross-species evidence for a critical role of OFC in mod

115 Thus, we found comprehensive cross-species evidence for chronic pain being a state of

116 These findings provide cross-species evidence of a novel strategy to enhance ex

117 Cross-species evidence suggests that safety signal learn

118 Using a cross-species experiment, we estimated that approximatel

119 These analyses and cross-species experiments in Caenorhabditis elegans and

120 We used cross-species expression experiments to show that Alx1 p

121 eview, we discuss the challenges specific to cross-species extrapolation of neutrophil function durin

122 he molecular basis of sperm-egg recognition, cross-species fertilization, and the barrier to polysper

123 This novel class of cross-species FPR2/Fpr2 agonists should enable translati

124 We used cross-species functional analysis of Drosophila Labial a

125 We propose a cross-species gene classification across the Full Spectr

126 Cross-species gene expression analyses classified SB-dri

127 Cross-species gene expression analysis revealed that the

128 ower compared to other ad hoc approaches for cross-species gene set analysis.

129 about the effect of complex gene homology on cross-species gene set analysis.

130 ific TFs affect the expression of conserved, cross-species genes during evolution.

131 hybrid gene expression matrix of 2.3 million cross-species genes in the 735 human fecal samples and 1

132 uence of various DNA and protein features on cross-species genetic interchangeability and evolutionar

133 loratory analysis of the OFC synaptome found cross-species genetic links to alcohol intake in discret

134 ifier, making it one of the few instances of cross-species genetic modifiers of monogenic traits.

135 ly isolated simian adenoviruses that contain cross-species genome recombination events from three hos

136 Mechanistically, cross-species genomic analyses and complete ciliary resc

137 chemoprevention, here we perform integrated cross-species genomic analysis of cuSCC development thro

138 We define the cross-species genomic landscape of tumors induced by an

139 in-protein interactions and information from cross-species genotype-phenotype annotation.

140 predation by Acinetobacter baylyi increases cross-species HGT by orders of magnitude, and we observe

141 nal MRI and, on the other hand, by imperfect cross-species homologies in animal model systems.

142 dings across species, neuroscience relies on cross-species homologies, particularly in terms of brain

143 oach, called XGSA, that explicitly takes the cross-species homology mapping into consideration when d

144 the result of ancient genetic variation and cross-species hybridization.

145 BRM has the capability to perform cross-species identifier lookups across common identifie

146 nize VAR2CSA, revealing a novel mechanism of cross-species immune recognition to falciparum malaria.

147 and Rhino-Deadlock co-evolution has produced cross-species incompatibilities, which may contribute to

148 Direct cross-species infection between koalas and gibbons is un

149 olor coryi) in Florida following the initial cross-species infection from bobcats.

150 ells could be critical in protecting against cross-species infection.

151 le, multidirectional, stable, and reciprocal cross-species infections of hosts from three species (hu

152 lation and GPI anchoring, may also influence cross-species infectivity.

153 e find that EMF models that exploit side and cross-species information improve imputation, especially

154 k of composable models that flexibly exploit cross-species information in the form of GI data across

155 Our work revealed the existence of cross-species inhibitory epitopes in VAR2CSA and calls f

156 nalyzed the progressions of 514 experimental cross-species inoculations of rabies virus, a widespread

157 These results uncover a dynamic cross-species interaction between human memory T cells a

158 These cross-species interactions have important implications f

159 pears to be a generic mechanism that enables cross-species interactions, as Pseudomonas aeruginosa ce

160 ansitions, abiotic and biotic responses, and cross-species interactions.

161 served in two or more species, rendering any cross-species interactome comparison immediately useful.

162 n the course of this work, we have assembled cross-species interactome comparisons that will allow in

163 Finally, cross-species interactome mapping demonstrates that coev

164 such as the JAK-STAT, immune deficiency and cross-species interferon-gamma pathways, have advanced o

165 f gammaretrovirus infection, and from recent cross-species jumps of gammaretroviruses from rodents to

166 Adaptive evolution is central to cross-species jumps, and this is why understanding the e

167 These findings document outcomes of cross-species lentiviral transmission events among felid

168 tanding of processes that promote successful cross-species lentiviral transmissions is highly relevan

169 which also revealed the limitations of using cross-species libraries.

170 A switchable cross-species liquid-repellent surface is developed that

171 Based on the existing cross-species literature on safety signal learning, they

172 s chromosomes within the Triticeae preserved cross-species macrocolinearity, except for a few species

173 These results demonstrate a cross-species, male-specific relation between UF microst

174 nguish lncRNAs from protein-coding RNAs in a cross-species manner without any prior knowledge.

175 -12p35 abolishes binding to IL-12Rbeta2 in a cross-species manner.

176 ors IL-12Rbeta2 and IL-23R in a murine/human cross-species manner.

177 ic discovery and diagnostics, integration of cross-species mapping efforts with the Mammalian Phenoty

178 resent distinct species, with no evidence of cross-species mating.

179 high level of MAGL specificity; this enabled cross-species measurement of MAGL brain expression (B(ma

180 Cross-species molecular comparison of mouse and human CL

181 emory and will serve as a foundation for our cross-species, multitechnique approach aimed at elucidat

182 and demonstrate the utility of our method in cross species network inference.

183 lts highlight the utility of an integrative, cross-species network approach to drug discovery.

184 f single organisms, and the establishment of cross-species networks.

185 stand how closely related arenaviruses elude cross-species neutralization by investigating the struct

186 progression and demonstrate the potential of cross-species oncogenomic approaches combined with mouse

187 ference in rodent SAMD9L poses a barrier for cross-species OPXV infection and that OPXVs have evolved

188 different rodent species poses a barrier for cross-species OPXV infection.

189 These results establish a cross-species paradigm for studying the problem of infer

190 Therefore, cross-species PAS identification, which enables the poss

191 el deep learning method named Poly(A)-DG for cross-species PAS identification.

192 Cross-species pathway transplantation enables insight in

193 study SCAs in vivo We have isolated a 258 bp cross-species PC-specific enhancer element that can be u

194 In comparative cross-species perspective, humans experience unique phys

195 ine pharmacodynamic models and an acceptable cross-species pharmacokinetic profile and was advanced a

196 ketamine as a model for psychosis, show that cross-species pharmacological experiments targeting rewa

197 Sleep is a cross-species phenomenon whose evolutionary and biologic

198 nd prove the utility of systematic human and cross-species phenomics analyses in highly heterogeneous

199 It also incorporates cross-species phenotypes and associations to include res

200 ortant anthelmintic is supported by a broad, cross species polypharmacology with PZQ modulating signa

201 Furthermore, to explore the cross-species prediction capability of LoopPredictor, we

202 s, such as rabbit, show robust resistance to cross-species prion conversion.

203 e prion seed are the primary determinants of cross-species prion specificity both in vivo and in vitr

204 beta-sheets and lower the energy barrier for cross-species prion transmission, potentially because of

205 t ChAd63-MVA PfUIS3 can also provide partial cross-species protection against challenge with wild-typ

206 hat a system of affinity-matured, microbiota cross-species-reactive IgA is a common aspect of SIgA-mi

207 This microbiota cross-species reactivity did not correlate with antibody

208 anti-human leukocyte antigen (HLA) antibody cross-species reactivity with swine leukocyte antigen (S

209 on ECM accumulation and offers a convenient cross-species readout that does not require antibodies.

210 ted by all MHC-E molecules tested, including cross-species recognition of human and MCM SIV-infected

211 Here we use cross-species regulatory comparisons between gnathostome

212 Here, we quantify the cross-species relationships between presence of dispersa

213 We used cross-species rescue experiments in Cd2ap(KD) zebrafish

214 Future cross-species research on the effects of absence of the

215 erbal marker of autism for developmental and cross-species research.

216 Using cross-species sequence capture, phylogenomics and genome

217 imbic cortex/area 25 projections, supporting cross-species similarities in OFC topography.

218 a/interspecies in silico approach based on a cross-species similarity search and deeply investigate t

219 genome of coronaviruses makes them adept at cross-species spread while enabling a robust understandi

220 Together, complementary cross-species studies are elucidating principles of adap

221 r phenomena were so difficult to sample that cross-species studies of biochemistry were rare and comp

222 ace additional cognitive demands with little cross-species test-relevance.

223 onaviruses (CoVs)-SARS-CoV and MERS-CoV-have crossed species to cause severe human respiratory diseas

224 st our method, we use four species and build cross-species training sets with two of them and evaluat

225 Cross-species transcriptomics defined distinct glutamate

226 Cross-species transcriptomics showed that both models ar

227 low moisture stress hardy crops can help in cross species transfer and validation confirming stress

228 erefore, GALV and KoRV may have arisen via a cross-species transfer from an intermediate host whose r

229 ather, they became infected with SIV through cross-species transfer from sooty mangabeys in captivity

230 of genetic incompatibilities preventing the cross-species transfer may explain host specificity, the

231 have served as a potential reservoir for the cross-species transfer of adenoviruses to other hosts, a

232 Cross-species transfer of sperm and active seminal fluid

233 nt, but existing Vitis marker platforms have cross-species transfer rates as low as 2%.

234 suggest that the Spok genes disperse through cross-species transfer, and evolve by duplication and di

235 thy participants, whereas they performed the cross-species-translated five-choice CPT (5C-CPT).

236 Furthermore, cross-species translation is limited by inconsistent fin

237 The startle eye-blink is the cross-species translational tool to study defensive beha

238 o experiments that directly test the in vivo cross-species transmissibility of SIVcpz strains to huma

239 The direction of any cross species transmission and the drivers for this cann

240 ces) in China to study their macroevolution, cross-species transmission and dispersal.

241 Here, we examine the cross-species transmission and mammalian adaptation of t

242 mised individuals and warrant studies on the cross-species transmission and pathogenesis of this nove

243 f value in identifying viral determinants of cross-species transmission and pathogenicity of novel in

244 ge gap is essential for better understanding cross-species transmission and predicting the likelihood

245 roach to examine Brucella abortus evolution, cross-species transmission and spatial spread in the GYE

246 y only specific SIVcpz strains have achieved cross-species transmission and what transmission risk mi

247 We also found that the cross-species transmission barrier of SIVcpz to humans c

248 and domestic cats were rare, suggesting that cross-species transmission between guignas and domestic

249 nce of HIV from nonhuman primates.IMPORTANCE Cross-species transmission episodes can be singular, dea

250 spread to large urban centers following one cross-species transmission event.

251 he mammalian hepadnaviruses, indicating that cross-species transmission events have played a major ro

252 non provides a unique opportunity to examine cross-species transmission events leading to new lentivi

253 es appear to have emerged through successful cross-species transmission events on more recent time sc

254 ses infect wild and domestic carnivores, and cross-species transmission is believed to occur.

255 provide insight into immune evasion and the cross-species transmission of 229E and related coronavir

256 ndemic HIV-1 (group M) emerged following the cross-species transmission of a simian immunodeficiency

257 We previously reported natural cross-species transmission of a subtype of feline immuno

258 rovirus (KoRV) most likely originated from a cross-species transmission of an ancestral retrovirus in

259 Cross-species transmission of CPV occurs as a result of

260 It began following the cross-species transmission of EBOV from an animal reserv

261 ticular, PA-X 195K might have contributed to cross-species transmission of H7N9, H5N6, and H1N1/2009

262 s, we simulated what might happen during the cross-species transmission of HSV-1 and found that the D

263 luenza A viruses among various host species, cross-species transmission of influenza A viruses occurs

264 anine populations are examples of successful cross-species transmission of influenza A viruses.

265 strated that PA-X plays an important role in cross-species transmission of influenza viruses.

266 n of PA-X because of its potential impact on cross-species transmission of influenza viruses.IMPORTAN

267 man immunological compatibility, the risk of cross-species transmission of porcine endogenous retrovi

268 Cross-species transmission of prophages is not uncommon.

269 f non-self recognition that protects against cross-species transmission of retroviruses.

270 ciency virus type 1 (HIV-1) is the result of cross-species transmission of simian immunodeficiency vi

271 ar bases for strain-specific host ranges and cross-species transmission of these human and animal RVs

272 nitial and fundamental evidence for possible cross-species transmission of TTVs.

273 Australia (Wallacea), may be relevant to the cross-species transmission to gibbons in Southeast Asia

274 ults have recapitulated the events of SIVcpz cross-species transmission to humans and identified muta

275 distribution, may have played a key role in cross-species transmission to other taxa.

276 Evidence of cross-species transmission was also observed with TFHBV.

277 Upon cross-species transmission, AlHV-1 induces malignant cat

278 y in wildlife and determinants of successful cross-species transmission, or spillover, are therefore

279 BTV but are less likely to be important for cross-species transmission, sheep and cattle continue to

280 the current pandemic and confirmed cases of cross-species transmission, the question of the extent t

281 uenza virus (AIV) could overcome barriers to cross-species transmission.

282 cognition and is an important determinant of cross-species transmission.

283 ns into the genetic alterations required for cross-species transmission.

284 er of pathogens shared is a growing risk for cross-species transmission.

285 echanisms for RV diversity, host ranges, and cross-species transmission.

286 This is the first in vivo study of SIVcpz cross-species transmission.

287 ir, and novel host that shape the outcome of cross-species transmission.

288 humans have animal origins and arose through cross-species transmission.

289 ined whether SERINC5 represents a barrier to cross-species transmissions and/or within-species viral

290 and predicting the likelihood of additional cross-species transmissions of SIV into humans.

291 We identified 268 hits, and cross-species validation found 32 hits that also disrupt

292 discuss approaches for data integration and cross-species validation.

293 The development of tasks with cross-species validity may enable better prediction of t

294 show that our model explains over 40% of the cross-species variation in LL under contrasting light en

295 The results support the view that cross-species variation in pitch perception reflects the

296 As Garcia and Dunn [1] point out, cross-species variation in vocal and anatomical relation

297 The resulting map offers a cross-species view of conserved, stable protein assembli

298 ts the value of PERV inactivation to prevent cross-species viral transmission and demonstrates the su

299 fied several genomic positions indicative of cross-species virus recombination events among other bet

300 PORTANCE Understanding the driving forces of cross-species virus transmission is central to understan