ライフサイエンスコーパス: crosslinking

1 oderate to minimal inhibition of collagen IV crosslinking.

2 odes a lysyl oxidase that catalyzes collagen crosslinking.

3 cting tracks form through oxidative tyrosine crosslinking.

4 PAI-1), and fibrin formation, but not fibrin crosslinking.

5 gnitude larger than the conventional thermal crosslinking.

6 resistance is a structural consequence of LD-crosslinking.

7 identified key differences in peptidoglycan crosslinking.

8 hought to initiate colorectal cancer via DNA crosslinking.

9 incorporation into Gln residues, and protein crosslinking.

10 g loading (95% w/w) were prepared by thermal crosslinking.

11 iate chain-growth polymerization and polymer crosslinking.

12 ecreased with desolvation and increased with crosslinking.

13 he solubility of oat protein despite limited crosslinking.

14 tein biotinylation with RNA-protein chemical crosslinking.

15 equirements of LOXL2 that enable collagen IV crosslinking.

16 networks through rapid binding and filament crosslinking.

17 PAGE bands did not show any evidence of zein crosslinking.

18 en hydrogels through covalent intermolecular crosslinking.

19 bers is prepared by dripping, diffusion, and crosslinking.

20 ses thiol-vinyl sulfone Michael addition for crosslinking.

21 oxacillin and showed increased peptidoglycan crosslinking.

22 ECM), (3) preserved collagen composition and crosslinking, (4) a decellularized material milieu with

23 arrying(5), tracking, imaging(6) and partner crosslinking(7), the range of functional groups that can

24 Subsequent reversible DA crosslinking achieved a controlled aggregation with diff

25 We found that lateral crosslinking activities have a much greater effect on MT

26 effect on MT stability than do longitudinal crosslinking activities, and that introducing a bias tow

27 while this process is opposed by myosin and crosslinking activities.

28 is independent of its autopeptidase and DNA-crosslinking activities.

29 ys679Met FXIII-A demonstrated reduced fibrin crosslinking activity in vitro.

30 o the rGO materials in two ways: (i) using a crosslinking agent - glutaraldehyde (GA) and (ii) by for

31 thesized EC2629, a folate conjugate of a DNA crosslinking agent based on a novel DNA-alkylating moiet

32 The combination of HA in a high-viscosity crosslinking agent with DBG improves the bone repair pro

33 ess, water-based ink containing a reversible crosslinking agent, ammonium persulfate.

34 e, it is demonstrated that, by introducing a crosslinking agent, it is possible to drastically alter

35 ombination of DBG and HA in a high-viscosity crosslinking agent.

36 combination of DBG and HA in a low-viscosity crosslinking agent; group DBG/HV: CSD filled by the comb

37 ss of MCM8IP confers cellular sensitivity to crosslinking agents and PARP inhibition.

38 DNA crosslinking agents are commonly used in cancer chemothe

39 After the mixture of the AuNPs and the crosslinking agents were injected to react with the cata

40 Using hypersensitivity to the DNA crosslinking agents, mitomycin C and olaparib, as proxie

41 ation of the AuNPs was triggered through the crosslinking agents, resulting in the color of the AuNPs

42 ular viability in response to treatment with crosslinking agents.

43 ilure, and hypersensitivity to aldehydes and crosslinking agents.

44 that protects cells against the toxicity of crosslinking agents.

45 re treatment promoted amylopectin side chain crosslinking and amylose-stearic acid complex formation.

46 Using photoactivatable ribonucleoside crosslinking and an innovative biotinylated Cp retrieval

47 motifs at cell surface resulting in receptor crosslinking and apoptosis induction.

48 lution RNA-RNA interaction identification by crosslinking and capture (iRICC) to identify sequences m

49 spectra results indicated increased collagen crosslinking and chemical reaction between the adhesive

50 Dehydrothermal crosslinking and concentration of the MDM influenced the

51 els can be structurally fused by interfacial crosslinking and coupled as input and output modules to

52 (200 AzU/g) were used for IgE binding, TGase-crosslinking and functional property characterization.

53 Using in vivo RNA-protein crosslinking and gel shift experiments, we reveal that y

54 iMARGI starts with in situ crosslinking and genome fragmentation, followed by conve

55 Crosslinking and immunoprecipitation (CLIP) allows for m

56 Here, we use a unique blend of crosslinking and immunoprecipitation (CLIP) and NMR spec

57 e nucleotide resolution in Argonaute1 (AGO1) crosslinking and immunoprecipitation (CLIP) data.

58 Crosslinking and immunoprecipitation (CLIP) methods enab

59 We developed NOVA2 cTag-crosslinking and immunoprecipitation (CLIP) to generate

60 teins is greatly facilitated by the enhanced crosslinking and immunoprecipitation (eCLIP) method.

61 ermore, by integrating SHAPE and fSHAPE with crosslinking and immunoprecipitation (eCLIP) of desired

62 We used individual-nucleotide resolution UV crosslinking and immunoprecipitation (iCLIP) for the RNA

63 Using an improved CLIP (crosslinking and immunoprecipitation) method, we perform

64 pan-neuronally expressed GFP::CAR-1 using a crosslinking and immunoprecipitation-based approach.

65 gel paints that decouple polymerization from crosslinking and interlinking.

66 shown to be the result of antibody-mediated crosslinking and internalization of receptors.

67 Using in vivo UV-crosslinking and mass spectrometry, we identified a C-te

68 These structures, along with crosslinking and molecular dynamics simulation results,

69 e basic physicochemical principles of matrix crosslinking and osmotic swelling are universal, our fin

70 Here, we have undertaken crosslinking and other experiments to address more fully

71 ed with oligo (dT)-conjugated beads after UV-crosslinking and profiled by proteomics (termed mRBPome

72 Complementary crosslinking and sequencing data for Hel2 revealed bindi

73 n have also been suggested to be involved in crosslinking and stabilization of the lubricating superf

74 (FFPE) tissues requires reversal of chemical crosslinking and the removal of reagents that are incomp

75 and ovarian cancer cells to promote collagen crosslinking and tumor cell invasion.

76 tubule dynamics, motor proteins, microtubule crosslinking, and chromatid cohesion can modulate spindl

77 The three processes-polymerization, crosslinking, and interlinking-usually concur.

78 supported using a combination of mutational, crosslinking, and kinetic analyses, and long-timescale m

79 rofiled to determine potency and the site of crosslinking, and subsequently developed as reporters in

80 tion of the structure using footprinting and crosslinking approaches.

81 tions, virtually all existing strategies for crosslinking are poorly reversible, chemically modifying

82 This revealed seven peaks of spliceosomal crosslinking around branchpoints (BPs) and splice sites.

83 We developed a cysteine crosslinking assay to constrain clamp movements and stud

84 Here we introduce chemical-crosslinking assisted proximity capture (CAP-C), a metho

85 ation of chromatin in cells mainly relies on crosslinking-based chromosome conformation capture techn

86 modifications of analytes, including complex crosslinking between nucleophilic moieties.

87 The extracellular actuation by surface CD20 crosslinking boosts robust activations of numerous intra

88 nsport modeling, further confirm that ligand crosslinking boosts thermal transport.

89 m concentration of mechanophores required to crosslinking by about 100-fold compared to previous exam

90 and that, under naive conditions, FcgammaRI crosslinking by IgG-IC directly activates the somata and

91 ggested different potentials for inter-spike crosslinking by IgGs on viruses, and characterized IgGs

92 ent peptidoglycan synthesis or peptidoglycan crosslinking by penicillin-binding protein 2 (PBP2) are

93 d with inhibitors that prevent peptidoglycan crosslinking by penicillin-binding protein 3 (PBP3/FtsI)

94 h identical polymer components but different crosslinking capacities to enable the investigation of m

95 e mechanical properties of tendon or whether crosslinking changes in response to stretching or relaxa

96 ercaptopropionic acid linker and zero-length crosslinking chemistry (EDC/NHS).

97 Here, we test this model by covalently crosslinking ClpA to ClpP to prevent rotation.

98 alyst has been produced by precipitation and crosslinking (combi-CLEAs) of beta-galactosidase and glu

99 ics simulations to optimise the selection of crosslinking compounds that overcome this trade-off rela

100 crosslinking (crosslinker concentration and crosslinking condition) on molecular mobility and physic

101 ach blend and were inversely affected by the crosslinking conditions.

102 er systems of stevia extracts independent of crosslinking conditions.

103 It is unknown how the crosslinking contributes to the mechanical properties of

104 e for real-time super-resolution imaging and crosslinking control.

105 Here, the use of photo-crosslinking, coupled with quantitative crosslinking mas

106 Influence of crosslinking (crosslinker concentration and crosslinking

107 e the cost effectiveness of corneal collagen crosslinking (CXL) for progressive keratoconus from the

108 to corneal transplantation; corneal collagen crosslinking (CXL) is a relatively non-invasive procedur

109 n alpha-actinin-4 (ACTN4)-an important actin crosslinking cytoskeletal protein that provides structur

110 based on the incorporation of short-distance crosslinking data as constraints in discrete molecular d

111 sion yeast whole-cell poly(A)(+) RNA-protein crosslinking data provide information on the organizatio

112 Analysis of in-cell crosslinking data reinforces the notion that simple C-pa

113 our thermodynamic model to published in vivo crosslinking data reveals quantitative agreement between

114 of 4.1 angstrom and combine it with protein crosslinking data to determine the molecular architectur

115 le using independent scattering and chemical crosslinking data.

116 ism, surface modification, and long-distance crosslinking data.

117 ure, and modulus along with the variation of crosslinking densities.

118 n adjacent crosslinks, network mesh size and crosslinking density as a function of crosslinker additi

119 Vs to overcome the confinement, and a higher crosslinking density facilitates a fluctuating transport

120 Hence, crosslinking density offers a simple method to enhance p

121 crosslinking temperature, by increasing the crosslinking density, provided a second avenue to enhanc

122 Compared to original uncrosslinked nanogels, crosslinking did not change particle size, polydispersit

123 Upregulation of collagen matrix crosslinking directly increases its ability to relieve s

124 repared from 30% v/v ethanol without calcium crosslinking displayed rapid peptic digestion in less th

125 er et al. (2017) show that by non-covalently crosslinking DNA, BAF promotes chromosome coalescence, p

126 a so far uncharacterized hurdle, DNA-protein crosslinking (DPC), by insertion sequence (IS)-mediated

127 tance of a regulatory protein to DNA affects crosslinking efficiencies.

128 Lysyl oxidase-like-1 (LOXL1), a vital crosslinking enzyme in elastin fiber maintenance, is ess

129 Thus, the crosslinking enzymes studied caused significantly differ

130 ncoming virion RNAs are labeled with 4SU, so crosslinking events specifically occur between proteins

131 and which detects and quantifies protein-DNA crosslinking events within the aligned profiles.

132 Here we show by crosslinking experiments that the direct interaction is

133 -guided mutagenesis and in vitro and in vivo crosslinking experiments, this study provides an unprece

134 for inhibiting fibrinolysis by irreversibly crosslinking fibrin and antifibrinolytic proteins.

135 Corneal collagen crosslinking for progressive keratoconus is cost effecti

136 amino acids will enhance the use of chemical crosslinking for studies of protein-protein and protein-

137 By adjusting the molar ratio of crosslinking functional groups, the tensile strength was

138 rocessing including resin infusion, onset of crosslinking, gel time, degree and rate of curing.

139 reted protein, acidic and rich in cysteine), crosslinking genes/enzymes (lysyl oxidase, lysyl oxidase

140 Rates and enrichment of dynamic crosslinking have profound consequences on domain morpho

141 Polymer crosslinking imbues chemical stability to thin films at

142 (TRAMP complex) and Nab3 (NNS complex) by UV crosslinking immediately following glucose withdrawal (0

143 on of the miRNAs, high-throughput sequencing crosslinking immunoprecipitation (HITS-CLIP) and biochem

144 UV crosslinking immunoprecipitation and sequencing (CLIP-se

145 In addition, we combine XRNAX with crosslinking immunoprecipitation sequencing (CLIP-seq) t

146 f gene expression changes and (iii) Enhanced Crosslinking Immunoprecipitation Sequencing (eCLIP-seq)

147 s, proteomics and high throughput sequencing crosslinking immunoprecipitation) to evaluate simultaneo

148 We used crosslinking immunoprecipitation- and RNA-sequencing to

149 fication of microRNA (miRNA) targets by Ago2 crosslinking-immunoprecipitation (CLIP) methods has prov

150 ing skin syndrome, respectively; loss of TG3 crosslinking in hair-cuticle formation leads to uncombab

151 st efficaciously blocked ONE-induced protein crosslinking in HDL and also prevented HDL dysfunction i

152 ion and Ca(2+) flux, were measured after IgE crosslinking in murine bone marrow-derived mast cells an

153 A high degree of crosslinking in the NS increased the loading efficiency

154 a suggest that YAP/TAZ may regulate collagen crosslinking in the palatal shelf mesenchyme, thus contr

155 inding of extensive irreversible TRMT2A-tRNA crosslinking in vivo following 5-Fluorouracil exposure i

156 Crosslinking increased the particle size and poly-disper

157 ntation measurements that demonstrate ligand crosslinking increases Young's modulus and sound velocit

158 Site-specific crosslinking indicated that F399 in SecA contacts riboso

159 BEAPR takes into account crosslinking-induced sequence propensity and variations

160 rotein organizing clathrin and TACC3 complex crosslinking K-fibers.

161 a large protein family that is implicated in crosslinking keratin intermediate filaments during hair

162 loss of FXIIIa (transamidase-activated form) crosslinking leads to defects in blood coagulation in FX

163 ble hair syndrome; the predicted loss of TG6 crosslinking leads to spinocerebellar ataxia-35; and los

164 Here, we show that crosslinking mammalian tissues with formaldehyde results

165 eport cryo-electron microscopy (cryo-EM) and crosslinking mass spectrometry (CLMS) studies of yeast R

166 Here, we present a femtosecond laser-induced crosslinking mass spectrometry (fliX-MS) workflow, which

167 hoto-crosslinking, coupled with quantitative crosslinking mass spectrometry (QCLMS), offers an opport

168 yo-EM) structure of gammaTuRC, combined with crosslinking mass spectrometry analysis, reveals an asym

169 del of the Ric8A/Galpha complex derived from crosslinking mass spectrometry and molecular dynamics si

170 elaxation enhancement (PRE) NMR and chemical crosslinking mass spectrometry confirm the repressive he

171 Crosslinking mass spectrometry is a powerful tool to ass

172 We used EM and crosslinking mass spectrometry to dissect five conformat

173 or probing biomolecular interactions and for crosslinking mass spectrometry.

174 Here, we use a combination of photo-crosslinking, mass spectrometry, solution scattering, an

175 integrate cryoelectron microscopy (cryo-EM), crosslinking-mass-spectrometry and biochemical and cellu

176 in other organisms, suggesting that DAP-DAP crosslinking may be a general mechanism for regulating b

177 sted that DM is linked to KC, mainly via the crosslinking mechanism, but scientific evidences are lac

178 valuate two non-enzymatic structural protein crosslinking mechanisms, Fenton chemistry and glycation,

179 orks (SilDNs) that participate in orthogonal crosslinking mechanisms-photocurable thiol-ene reactions

180 lectively, this evidence strongly supports a crosslinking-mediated endocytosis mechanism.

181 ting, customized-transcriptome profiling and crosslinking-mediated interactome analyses, we discovere

182 This research co-opts this crosslinking-mediated internalization for efficient intr

183 eraction between the alkyl or pai-conjugated crosslinking molecules is due to hydrogen bonding betwee

184 sponse to nonlinear forcing, whereas varying crosslinking motifs have little impact on the microscale

185 focal microscopy to characterize how varying crosslinking motifs impact the mesoscale mechanics and m

186 d with a combinational dynamic and permanent crosslinking network through chain entanglement and DNA

187 Despite the lack of crosslinking observed, rheological and textural analysis

188 cascade to control the force which triggers crosslinking of a mechanochromic polymer of spirothiopyr

189 Ex vivo, crosslinking of alpha2-antiplasmin and fibrin was impair

190 to label living bacteria followed by in vivo crosslinking of bacteria proteins to their interacting h

191 in is selective for, but not limited to, the crosslinking of collagen IV.

192 , or chemical modification, such as covalent crosslinking of DNA strands.

193 Crosslinking of Fc with FcgammaRIIB mediates antibody-de

194 Subsequent physical crosslinking of G3BP clusters drives RNA molecules into

195 However, hyper-crosslinking of HER2 has been shown to override the rece

196 in Saccharomyces cerevisiae and demonstrated crosslinking of histone H2A to Paf1 complex subunit Rtf1

197 Ag-mediated crosslinking of IgE-FcepsilonRI complexes activates mast

198 ly synthesized with the chemical or physical crosslinking of monomers or macromers.

199 Generally, crosslinking of pectin polymer with Ca(2+) cations in th

200 n two distinct but coupled steps, an orderly crosslinking of pilin monomers and subsequent anchoring

201 Lipid peroxidation product-mediated crosslinking of proteins in high-density lipoprotein (HD

202 fic IgE initiates the allergic cascade after crosslinking of receptors on effector cells.

203 CD73 dimer in a bivalent manner, implicating crosslinking of separate CD73 dimers in its mechanism of

204 the backbone allowed for the intramolecular crosslinking of single chains via the addition of [Pt(1,

205 this article is based on the hypothesis that crosslinking of starch can make it a potential wall mate

206 have provided mechanistic demonstration that crosslinking of surface receptors can be leveraged to el

207 These data suggest a defect in crosslinking of surface-active molecules in OA and provi

208 Mast cell (MC) mediator release after crosslinking of surface-bound IgE antibody by ingested a

209 UV-crosslinking of synthesized methacrylate-functionalized

210 he periphery, suggesting a reduced degree of crosslinking of the chromatin.

211 tration upon immunoglobulin E (IgE)-mediated crosslinking of the high-affinity IgE receptor (Fcepsilo

212 The site of crosslinking of the optimised probe, as well as its abil

213 These results indicate that increased crosslinking of the peptidoglycan polymer can be detrime

214 bio-orthogonal two-photon cycloaddition and crosslinking of the polymers at wavelengths longer than

215 s coated with antibodies through concomitant crosslinking of their T cell receptor (TCR) and FcgammaR

216 NA interactome capture (RIC) uses in vivo UV crosslinking, oligo(dT) capture, and proteomics to ident

217 anovinylcarbazole nucleoside photo-inducible crosslinking on single molecular targets and developed a

218 centrations and Ca(2+) ions in both steps of crosslinking on the swelling degree (SD) and mechanical

219 Soy and pea isolates underwent extensive crosslinking on their own, but heteropolymers were not o

220 Despite no obvious selection pressure for LD-crosslinking or lysozyme resistance in C. crescentus, th

221 Crosslinking or RNA immunoprecipitation followed by sequ

222 in order to regulate microtubule-microtubule crosslinking or sliding, KIFC2 and KIFC3 need to interac

223 ence polarization measurements, but chemical crosslinking paired with mass spectrometry analyses trap

224 to support our conclusion that non-enzymatic crosslinking pathways likely contributed to stabilizing,

225 protocol precisely characterizes protein-DNA crosslinking patterns by combining chromatin immunopreci

226 P-exo assay precisely delineates protein-DNA crosslinking patterns by combining chromatin immunopreci

227 suggest that principled analyses of ChIP-exo crosslinking patterns enable inference of spatial organi

228 computational framework that aligns ChIP-exo crosslinking patterns from multiple proteins across a se

229 the position and strength of BPs affect the crosslinking patterns of spliceosomal factors, which bin

230 We show that, upon subtle changes in crosslinking patterns, composites can exhibit two distin

231 al accessibility, which align well to nearby crosslinking peaks.

232 When exposed to 365 nm UV light, additional crosslinking points are created by the photo-induced dim

233 l as the large number of contact or physical crosslinking points between adjacent BC nanofibres, furt

234 The formation of the crosslinking points increases modulus and glass transiti

235 specificity while precisely registering the crosslinking position in motif sites.

236 We utilize a covalent crosslinking probe to trap transient interactions betwee

237 the common strategy of utilizing mutants or crosslinking probes to stabilize intermediates is prone

238 osfamide (TH-302) is a hypoxia-activated DNA-crosslinking prodrug currently in clinical development f

239 he frictional forces produced by the mitotic crosslinking protein PRC1 that resist microtubule slidin

240 of molecular components, such as motors and crosslinking proteins between microtubules, on the colle

241 ble actin filaments, rigid microtubules, and crosslinking proteins.

242 nt-detachment dynamics of motors and that of crosslinking proteins.

243 nding interface of the bait protein used for crosslinking, providing structural information of the in

244 The crosslinking rate is three orders of magnitude larger th

245 e concentration of such bonds, and hence the crosslinking rate, is controlled by force-dependent diss

246 re that is captured in situ through a simple crosslinking reaction.

247 This formation did not need any additional crosslinking reactions.

248 Receptor crosslinking requires binding of antibodies to multiple

249 The structures and photo-crosslinking results also suggest that the conserved aro

250 ping RNAPI by Miller chromatin spreads or UV crosslinking revealed 5' enrichment and strikingly uneve

251 complex by solution scattering and chemical crosslinking, revealing a 1:2 complex that can form high

252 pping method, Fluorouracil-Induced-Catalytic-Crosslinking-Sequencing (FICC-Seq), in order to identify

253 uld potentially be inferred by analyzing how crosslinking signatures vary between its subunits.

254 mplexes will result in different protein-DNA crosslinking signatures, analysis of ChIP-exo tag enrich

255 c identification of interacting proteins and crosslinking sites.

256 to loss of Short stop (Shot), a cytoskeletal crosslinking spectraplakin protein that we previously fo

257 e its reactive surface groups for favour the crosslinking step.

258 Here, a sequential targeting in crosslinking (STICK) nanodelivery strategy is presented

259 ults from promoting antiparallel microtubule crosslinking, stopping microtubule plus-end dynamicity,

260 While crosslinking strategies can in principle be used to trap

261 A covalent and ionic dual-crosslinking strategy is proposed to manipulate the pore

262 The new crosslinking strategy preserves the surface chemistry of

263 Here we present a chemical crosslinking strategy that incorporates a photoreactive,

264 ucing consistent measurements of protein-DNA crosslinking strengths across multiple proteins, our app

265 igning a unique physical and covalent hybrid crosslinking structure.

266 the BamA substrate, consistent with previous crosslinking studies(10-12); the other edges of the BamA

267 We present results of molecular modeling, crosslinking studies, microscale thermophoresis and cell

268 f a photoreactive unnatural amino acid (UAA) crosslinking system to capture protein interactions in t

269 Elevating the crosslinking temperature, by increasing the crosslinking

270 cells are mixed with 3-PBA-protein conjugate crosslinking that can be visually detected occurs.

271 M and mechanical tests documented successful crosslinking that enhanced the structural properties of

272 his, we developed an approach termed in situ crosslinking that permits the printing of non-viscous, p

273 Upon photo-crosslinking the hydrogel precursor, object positioning

274 vercome this thermal-transport bottleneck by crosslinking the ligands to exchange a weak van der Waal

275 ular transglutamination reaction, covalently crosslinking the Ube2N and Ub subunits effectively inact

276 parameters including GelMA concentration, UV crosslinking time and printing configuration were identi

277 eadgroups form multiple hydrogen bonds, thus crosslinking TLRs into functional complexes.

278 Following photo-affinity crosslinking to 4-azidoSA and immuno-selection with an a

279 s, we demonstrated the importance of genipin crosslinking to avoid membrane detachment in alginate mi

280 tivities of peptidoglycan polymerization and crosslinking to build the cell wall.

281 SiMPull) assay combined with in vivo protein crosslinking to count individual alpha-SYN protein and a

282 mechanical strength of alginate-based MN by crosslinking to facilitate skin penetration, thus suppor

283 We employed site-specific crosslinking to identify proteins that directly bind the

284 This study sought to utilize enzymatic crosslinking to modulate the properties of chickpea-stab

285 hat of STP isomerization, the cascade limits crosslinking to overstressed regions of the material, wh

286 ymerization of new glycan strands with their crosslinking to the existing peptidoglycan meshwork is u

287 tissue surface, resulting in fast temporary crosslinking to the surface.

288 rtion by the Bam complex using site-specific crosslinking to understand the molecular mechanisms that

289 and these changes restored the peptidoglycan crosslinking to WT levels.

290 ule nucleation, growth, and stability; thus, crosslinking tubulin by pairs of motor heads is not nece

291 udy, we introduce a workflow combining photo-crosslinking using sulfosuccinimidyl 4,4'-azipentanoate

292 form: viral Photo-Activatable Ribonucleoside CrossLinking (vPAR-CL).

293 Using thiol-specific crosslinking we provide rigorous proof of entrapment act

294 Using disulfide-bond crosslinking, we find that the first beta-strand of a la

295 ance, on spin-labeled protein, and disulfide crosslinking, we show that TRIM63 follows the structural

296 networks through microbial transglutaminase crosslinking were investigated.

297 Subsequent covalent crosslinking with amine groups on the tissue surface fur

298 Crosslinking with formaldehyde captured in vivo interact

299 he capture antibody (CAb) was immobilized by crosslinking with glutaraldehyde (GA) on the amino group

300 We hypothesized that collagen crosslinking would similarly stiffen tarsal plate tissue