ライフサイエンスコーパス: crossreactive

1 vely selected or non-selected were minimally crossreactive.

2 To test whether highly crossreactive alphabeta T cell receptors (TCRs) produced

3 These T cells showed a crossreactive and heteroclitic (stronger) response to de

4 etter understanding the extent and nature of crossreactive anti-fHbp antibodies.

5 Using a crossreactive antibody, we show that the embryonic expre

6 l benefits and treatment outcomes using less crossreactive antigens will enhance clinical and treatme

7 imed by higher amounts of self antigen or by crossreactive antigens.

8 ein present two clinically important and non-crossreactive antigens: core antigen (HBcAg), which appe

9 tic heart disease have provided evidence for crossreactive autoantibodies that target the dominant gr

10 To summarize, pathogenic mechanisms of crossreactive autoantibodies which target the valve in r

11 ry cells, formation of dysfunctional HDL and crossreactive autoantibodies.

12 ent NAbs that recognized epitopes conserved (crossreactive) between serotypes.

13 Shared sequences were enriched for allo-crossreactive CDR3betas and for Type 1 diabetes-associat

14 ique natural experiment to determine whether crossreactive cellular immunity limits symptomatic illne

15 itol (GPI) anchor that is recognized by anti-crossreactive determinant antibodies.

16 responses to donor antigens could spread to crossreactive determinants on self-proteins, thus perpet

17 areas have antibodies in their sera that are crossreactive for both helminth and malaria parasites ra

18 e thymus contains many T cells that are very crossreactive for peptide and MHC and that subsequent ne

19 aFEST) platform to identify T cell responses crossreactive for the spike (S) glycoproteins of SARS-Co

20 cific fusion inhibition activity; only 1 had crossreactive fusion inhibition activity against HIV-1/M

21 s IgE antibodies, are highly immunologically crossreactive glycoproteins exclusively expressed in pol

22 The crystal structure of the crossreactive huFab 1E6 in complex with fHbp variant 3 w

23 a now suggest that mutations associated with crossreactive material-negative fXI deficiency fall into

24 autoantibodies against collagen that are not crossreactive may form because of the release of collage

25 This is in part accounted for by crossreactive memory T cells, which can be employed in i

26 etermine the kinetics of strain-specific and crossreactive nAb emergence, we studied patient H, the s

27 The delayed appearance of high titer crossreactive nAbs in chronically infected patients sugg

28 the MN strain of HIV-1 (HIV-1/MN), and 2 had crossreactive neutralizing activity against the IIIB str

29 Nine of the 13 had crossreactive neutralizing activity against the MN strai

30 lly infected with HCV develop high-titer and crossreactive neutralizing antibodies (nAbs), yet fail t

31 In the absence of crossreactive neutralizing antibodies, CD8(+) T cells sp

32 rgp120 in MF59 can induce type-specific and crossreactive neutralizing antibody against B-subtype la

33 uick and simultaneous testing of potentially crossreactive NMBA and the identification of safe altern

34 allergy diagnostics enables the detection of crossreactive or species-specific allergen components.

35 In addition, crossreactive patterns were observed between different l

36 resulted from the presentation of the donor crossreactive peptide Kk 61-80 at the surface of recipie

37 a) production was measured by a specific non-crossreactive RIA.

38 overview of the various types of biomimetic crossreactive sensor arrays (also referred to as electro

39 Biomimetic crossreactive sensor arrays have been used to detect and

40 , FTK-OspA, in which the LFA-1alpha(L)/rOspA crossreactive T cell epitope was mutated to reduce the p

41 er studies are needed to determine how these crossreactive T cell responses affect clinical outcomes

42 Crossreactive T cells demonstrated significantly impaire

43 CDR1 and CDR2 amino acids dominated the most crossreactive TCR interface with MHC, including Vbeta8 4

44 Thus, broadly crossreactive TCRs arise at low frequency in the pre-sel

45 These data show that crossreactive TCRs can spotlight the evolutionarily cons

46 The lower avidity of crossreactive TCRs for SARS-CoV-2 may be the result of a

47 Negative selection of crossreactive TCRs led to clonal deletion but also recyc

48 However, Th17 cells that are crossreactive to Aspergillus fumigatus antigens can also

49 MAIT cells bearing TCRs crossreactive toward self are rare but commonly found wi

50 face of cells and also makes TCRs inherently crossreactive towards different peptides bound by the sa

51 t only of target enzyme inhibition, but also crossreactive with chemical xenobiotics that share molec

52 To identify HCV protein which possibly is crossreactive with M3R or which binds to this receptor,

53 by MHC molecules and elicit T cells that are crossreactive with microbial antigens and tumour-cell-as

54 ntracellular regions of the EGFR, but is not crossreactive with other HER-family members.

55 ut varied from noncrossreactive to extremely crossreactive with other peptides and MHCs.

56 able, and a nonspecific insulin immunoassay (crossreactive with proinsulin) was used.

57 eart valves revealed the presence of T cells crossreactive with streptococcal M protein and cardiac m

58 T cells specific for L144/R147 peptide were crossreactive with the native PLP-(139-151) peptide, pro

59 p variant 1, 13 huFabs were also found to be crossreactive with variants 2 and 3.