ライフサイエンスコーパス: crowd

1 pheral objects can be difficult to identify (crowding).

2 ramatically reduced the effectiveness of the crowd.

3 ronment inside a metazoan organism is highly crowded.

4 vice versa with weak motion and strong color crowding.

5 formation is lost in the visual system under crowding.

6 ent of the entire display strongly modulated crowding.

7 t may instead be attributed to local protein crowding.

8 motors or more slowly (30 min) aggregated by crowding.

9 y to produce winged offspring in response to crowding.

10 er activated regions with maximal isochronal crowding.

11 y stimuli tailored for the global aspects of crowding.

12 riments reveal a prominent role of molecular crowding.

13 dings via binding interactions and molecular crowding.

14 enerates apical expansion and apical nuclear crowding.

15 tions as ionic strength is increased without crowding.

16 isolation or surrounded by flankers to give crowding.

17 e micrometer scale, which we term organellar crowding.

18 ofoundly different than that of steady-state crowding.

19 ity of which is challenged by macromolecular crowding.

20 features and can contribute substantively to crowding.

21 ividing, likely in response to neighbor-cell crowding [1-6].

22 bered heteroaromatic rings at the sterically crowded 7,8 and 7',8' positions of BINOL.

23 pounds are extremely sensitive to the steric crowding about the boron atom, pointing to the crucial i

24 of RNAP to DNA, not much is known about how crowding acts on late initiation and promoter clearance

25 previously demonstrated that macromolecular crowding affects association of RNAP to DNA, not much is

26 ular environment through the addition of the crowding agent BSA, but not by sucrose polymers.

27 eotide probe as functions of ionic strength, crowding agent concentration, and crowding agent species

28 uilibrium phase boundary to lower protein or crowding agent concentrations.

29 strength, crowding agent concentration, and crowding agent species using single-molecule CLiC micros

30 ration of 8 kDa polyethylene glycol (PEG), a crowding agent.

31 upon binding, with polyethylene glycol as a crowding agent.

32 f facilitated diffusion of DBPs by molecular crowding agents and crowder-concentration-dependent enzy

33 nt reports indicate that, in the presence of crowding agents, tau can undergo liquid-liquid phase sep

34 rough the metal component or the presence of crowding agents.

35 ndividual cell could be isolated from a cell crowd and then extracted with ~0.5 muL of phosphate-buff

36 points of interest that they visit are more crowded and are therefore associated with higher risk.

37 functional, OMPs must fold and insert into a crowded and asymmetric OM that lacks much freely accessi

38 of knots and links by TopoII enzymes even in crowded and confined conditions.

39 ns so that their transient interactions in a crowded and heterogeneous environment of cytosol can be

40 estinal organoids by modifying intracellular crowding and elevating Wnt/beta-catenin signaling.

41 a molecular-level insight on the effects of crowding and host-guest interactions on azobenzene isome

42 f natural killer cells subjected to cellular crowding and hypoxia reveals widespread C-to-U mRNA edit

43 r extent, CD8-positive T cells upon cellular crowding and hypoxia.

44 Therefore, to capture such dynamic crowding and investigate its influence on transcription,

45 This RNA editing is induced by cellular crowding and mitochondrial respiratory inhibition to pro

46 virus 2 (SARS-CoV-2) transmission because of crowding and shared hygiene facilities.

47 eightened risks associated with events where crowding and travel were most likely (2-week-lag inciden

48 ynamics were sensitive to the degree of cell crowding and were similar in neighbouring cells.

49 analogical innovation and first steps using crowds and artificial intelligence (AI) to augment creat

50 ccurs in structurally organized, molecularly crowded, and dimensionally constrained amphiphilic fluid

51 mensionality, reaction type, reaction speed, crowding, and cell size.

52 isual area V2, approximated 'Bouma's Law' of crowding, and has subsequently been interpreted as a lin

53 luding exposure to aphid alarm pheromone and crowding, and, in one experiment, we assessed whether th

54 cal properties such as pH and macromolecular crowding are essential to all molecular processes in cel

55 Contact resistance and current crowding are important to nanoscale electrical contacts.

56 led extrusion and increased proliferation in crowded areas of the tissue.

57 However, using visual crowding as a well-controlled challenge, we previously s

58 We discuss molecular crowding as an important driver of condensation in these

59 oncentration profiles show clear evidence of crowding as nuclei reach close-packing and are quantitat

60 transcription depends critically on dynamic crowding as the gene expression resultant from dynamic c

61 -neighbour distances, this study underscored crowding at all surveyed fish landing beaches, and ident

62 iposomes, lipid composition of the membrane, crowding at the membrane, and strength of MreB synthesis

63 So far unexplored, molecular crowding at the surface of synthetic cells emerges as an

64 Proliferation-induced cellular crowding at the tissue scale triggers tension heterogene

65 nthesis of DPM is described (90% yield), and crowded beta-diketones featuring bulky o-biphenyl or m-t

66 f exogenous ligands driven by the sterically crowded binding sites.

67 height increases with cell surface molecular crowding but decreases with solution crowding by solutes

68 The nuclear environment is highly crowded by biological macromolecules, including chromati

69 These spaces are crowded by cells and extracellular matrix, generating ma

70 As the membrane becomes crowded by ENTH proteins, the polymer chain extends, inc

71 lecular crowding but decreases with solution crowding by solutes, both of which we confirm with molec

72 ons to test the performance of the wisdom of crowds by comparing three data aggregation rules across

73 s the gene expression resultant from dynamic crowding can be profoundly different than that of steady

74 t of a linear pathway, with the finding that crowding can have a redistributing effect on the effecti

75 In cells, molecular crowding caused by the presence of organelles, proteins,

76 ations including the dynamics of proteins in crowded cell membranes and the adsorption on nano-struct

77 How cargoes move within a crowded cell-over long distances and at speeds nearly th

78 The cytoplasm of bacterial cells is a highly crowded cellular compartment that possesses considerable

79 amics of DNA segments in spatially confined, crowded cellular compartments as well as during bacteria

80 r show, by using both an in vitro mimic of a crowded cellular environment and eukaryotic cell lysates

81 To approximate the crowded cellular environment, it is very important to pa

82 ference from promiscuous interactions in the crowded cellular environment.

83 ed from cryo-electron tomograms (cryo-ET) of crowded cellular environments is often limited owing to

84 -to-nanometer resolution of complexes inside crowded cellular environments.

85 anced facilitated diffusion of DBPs inside a crowded cellular milieu through, to our knowledge, novel

86 hts into gene regulation kinetics inside the crowded cellular milieu.

87 transitions during epidermal stratification crowded cellular spaces with liquid-like KGs whose coale

88 n be 13- to 163-fold higher in the molecular crowding cellular environment.

89 on and heterogeneity, such that epidemics in crowded cities are more spread over time, and crowded ci

90 rowded cities are more spread over time, and crowded cities have larger total attack rates than less

91 sive data on human mobility and predict that crowded cities worldwide could experience more prolonged

92 of the simulated cryo-ET is more complex and crowded compared with previous ones, it will pose a grea

93 e with dyslexia all exhibit increased visual crowding, compared to adults without dyslexia.

94 cipants aged 20-59 years and those living in crowded conditions (4.4% [3.5-5.6] for those living with

95 how enzymatic reactions could be affected by crowded conditions in the cellular milieu.

96 Such crowded conditions promote protein-protein interactions,

97 It is essential to study RNA under molecular crowding conditions to better predict secondary structur

98 le-time-scale dynamics over a broad range of crowding conditions, we develop and test an integrated a

99 onconclusive, e.g., if spectra are extremely crowded, coupling patterns are not resolved, or if symme

100 proposed a unified framework for simulating crowded cryo-electron tomogram images including non-defo

101 w catalyst for the preparation of sterically crowded cyclobutane structures is highlighted through th

102 ssembly of large multimeric complexes in the crowded cytoplasm is challenging.

103 ports diverse regulatory programs within the crowded cytoplasm.

104 at have become misfolded in the context of a crowded cytosol.

105 tically and experimentally, for steady-state crowding densities; however, temporal changes in crowdin

106 ding densities; however, temporal changes in crowding density ("dynamic crowding") have yet to be int

107 s of human perception have characterized how crowding depends on the properties of a visual display.

108 The more sterically crowded diplumbyne Ar(Pri(8))PbPbAr(Pri(8)) (Ar(Pri(8))

109 This double dissociation reveals that crowding disrupts certain combinations of visual feature

110 dilute conditions used in these experiments, crowding does not impact probe-plasmid interactions once

111 When regioisomers are possible, the more crowded (doubly ortho-substituted) product is formed pre

112 Regions with isochronal crowding during the baseline rhythm were predictive of V

113 vidence that localized increases in cellular crowding during wound closure promote the extrusion of n

114 The "soft interactions" model of the crowding effect also explained the alteration in kinetic

115 n insight into the mechanistic detail of the crowding effect, kinetic studies were conducted with var

116 at the reaction rate kon is increased by the crowding effect, while koff is changed only moderately.

117 ential implications for the understanding of crowding effects in the eye lens.

118 iscosities, along with possible PVP-mediated crowding effects, may explain the observed phenomena.

119 odel of a HeLa cell to capture intracellular crowding effects.

120 cle theory, commonly used for description of crowding effects.

121 e demonstrate that two-dimensional molecular crowding, emulated by the PEG molecules at the lipid bil

122 Here, we demonstrate that macromolecular crowding enhances the rate of late initiation and promot

123 A DNA strand displacement reaction in a crowded environment is also studied with the model and w

124 on cryotomography, we identified, within the crowded environment of eukaryotic cells, a unique nanosc

125 eroxiredoxin quaternary structure inside the crowded environment of living cells.

126 Diffusional motion within the crowded environment of the cell is known to be crucial t

127 otic chromosomes, whilst jostling within the crowded environment of the cell, cannot yet be achieved

128 modynamics of nucleic acid interactions in a crowded environment remain poorly understood.

129 The nucleus in eukaryotic cells is a crowded environment that consists of genetic code along

130 In cells, proteins are embedded in a crowded environment that controls their properties via m

131 t polypeptide exit site of the ribosome is a crowded environment where multiple ribosome-associated p

132 c physical constraints on probes inside this crowded environment will help inform studies on binding

133 tations of a crab inhabiting a flat, densely crowded environment, where most object motions are gener

134 urs in a timely and selective manner in this crowded environment.

135 t mabs reveal that diffusion coefficients in crowded environments are markedly impacted by intermolec

136 Nucleic acid interactions under crowded environments are of great importance for biologi

137 Protein dynamics in crowded environments is important for understanding prot

138 g range interactions on soft NPs dynamics in crowded environments, and help rationalize the design of

139 By migrating to less crowded environments, individuals can escape IC.

140 o continuously translate and rotate, even in crowded environments, thereby impacting the spatial orga

141 ve systems is how to prevent traffic jams in crowded environments.

142 amics of DNA duplex and hairpin formation in crowded environments.

143 tablished that both features show systematic crowded errors (biased predominantly toward the flanker

144 ze required for obtaining reliable, averaged crowd estimates.

145 for target-flanker similarity (with reduced crowding for dissimilar target/flanker elements).

146 We examined crowding for motion and color, two features that allow a

147 show that macaque monkeys exhibit perceptual crowding for target orientation that is similar to human

148 nonplanar structure that arises from steric crowding, forcing the amide side groups out of plane wit

149 oncentration-pressure curves and is thus not crowded from an osmotic perspective.

150 nts growing linearly in time - and suggested crowding from cell division at the apical surface drives

151 large-scale behavioral experiment with live crowds from two countries.

152 daily demand, congestion may rise when huge crowds gather in demonstrations, concerts or sport event

153 faces, their bulky disordered domains become crowded, generating steric pressure that destabilizes li

154 -helicenoids have an overlapping, sterically crowded geometry.

155 Here, we show via a minimal model that crowded hard-particle systems governed solely by entropy

156 Our results show that crowding has a strong effect on the initial concentratio

157 While research on the "wisdom of crowds" has found that information exchange can increase

158 mporal changes in crowding density ("dynamic crowding") have yet to be integrated with gene expressio

159 rthermore, this enhancement was sensitive to crowding - high surface loading reduced conjugates' abil

160 cerbate infectious disease risks by creating crowded, high-contact conditions and straining the capac

161 arginalised community with intense household crowding, highlights the need for coordinated, interdisc

162 urban or densely-populated or that had more crowded housing, air pollution, women, 20-49-year-olds,

163 Indistinguishable aggregates form in crowded in vitro solutions and in complex environments o

164 ibility of reducing LOS, triage time, and ED crowding in addition to improving the experience of pati

165 physiological protein levels upon molecular crowding in buffers that resemble physiological conditio

166 n of the Gaussian bending rigidity and their crowding in concert with the transmembrane cargo on the

167 ey responded differently to manipulations of crowding in Experiment 2.

168 ing interest in understanding macromolecular crowding in living cells and their effects on protein fo

169 34E amantadine-resistant mutant despite some crowding in the binding site by the glutamates.

170 ower the energy cost associated with protein crowding in the inner mitochondrial membrane.

171 We hypothesize that protein crowding in the OXPHOS system imposes packing stress on

172 effects caused by confinement and molecular crowding in the spatial organization of the chromosome.

173 t to solvation inhomogeneities and molecular crowding in these concentrated fluids.

174 or laboratory work, demonstrating how visual crowding increases with eccentricity and extending this

175 The crowding induced stability originates from the entropic

176 e infectious diseases, with a high degree of crowd interactions imposed substantial burdens on host c

177 the quaternization reaction in a sterically crowded intraannular position is investigated, and diffe

178 specific 20-nucleotide target sequence in a crowded intracellular environment packed with mega bases

179 The crowded intracellular environment, in contrast to in vit

180 addressable sub-diffraction volumes, within crowded intracellular environments.

181 Indeed, the biophysical behavior of water in crowded intracellular milieu is a long-debated issue.

182 to Klp9 molecules, suggesting that molecular crowding inversely correlates to cell size and might hav

183 Crowding is a profound loss of discriminability of visua

184 g is rather stable and that the stability of crowding is a stronger predictor for lifespan than the a

185 Although crowding is a ubiquitous phenomenon, since elements are

186 Importantly, macromolecular crowding is able to partially rescue G4Q from unfolding.

187 However, when crowding is introduced via 10% 8 kDa PEG, interactions b

188 Dynamic crowding is pertinent to nuclear biology because process

189 or long-term FRET measurements, we show that crowding is rather stable and that the stability of crow

190 s electrostatic control explains how protein crowding is spontaneously maintained at a constant level

191 A central rule of crowding is that it is stronger when the target and the

192 Crowding is the deleterious influence of surrounding obj

193 bject-selective mechanism predicts that when crowding is weak for one feature and strong for the othe

194 To test whether the wisdom of crowds is robust to partisan bias, we conducted two web-

195 By using the wisdom of the crowds, it is possible to transfer knowledge from one of

196 At higher crowding levels, the nucleoid becomes spherical, and its

197 igher along the long axes of the cell at low crowding levels.

198 ger predictor for lifespan than the absolute crowding levels.

199 (young children, sexual activity, household crowding, low income) probably increase the risk of acqu

200 at cargo recruitment into vesicles creates a crowded lumen that drives selectivity.

201 lamin-associated chromatin organization in a crowded macromolecular environment by systematically var

202 the degree of cellular hydration, molecular crowding, magnitude of turgor, and cellular integrity.

203 hild pneumonia (non-exclusive breastfeeding, crowding, malnutrition, indoor air pollution, incomplete

204 cytoplasm and its assembly is away from the crowded membrane surface.

205 Here I review colloid osmotic pressure as a crowding metric.

206 The integration of molecularly crowded microenvironments into membrane-enclosed protoce

207 fail to do so in elongated cells within the crowded midline, where tension is low, or in regions tha

208 ly entering another colony, especially under crowded modern apiary conditions.

209 function of the intrinsic properties of the crowded molecular environment.

210 es such as azobenzenes or spiropyrans within crowded molecular environments, which may allow control

211 mensional instances of optimal transport and crowd motion problems on a standard work station and a v

212 inance, game theory, industrial engineering, crowd motion, and more.

213 Despite the crowded nature of the cellular milieu, ligand-GPCR-G pro

214 erefore, this work demonstrates that dynamic crowding nontrivially alters transcription kinetics and

215 f cat fleas as vectors of human pathogens in crowded northeastern U.S, cities and suburbs where free-

216 We report that deficiencies in CROWDED NUCLEI (CRWN), which are candidate nuclear lamin

217 e connection between the lamin-like protein, CROWDED NUCLEI1 (CRWN1), and the chromatin- and PcG-asso

218 e ensembles (e.g., the average identity of a crowd of faces).

219 The functional task is challenged by a dense crowd of nonpartners obstructing the way.

220 an organisational phenotype that represents crowding of function in one hemisphere, or a reversal of

221 ion, and demonstrates how the macromolecular crowding of RPBs at the ribosome exit site enhances the

222 allenge is how to parameterize the degree of crowding of the cell interior or artificial solutions th

223 ked difference is attributable to the lesser crowding of the di-isopropylphosphino-substituted cataly

224 ps at the nitrogen, which surpass the steric crowding of triisopropylamine considerably, were prepare

225 roscopy allows us to quantify the effects of crowding on a comprehensive set of observables simultane

226 he study found that the effects of molecular crowding on both conformational dynamics and catalytic f

227 lyze and predict the effect of intracellular crowding on enzymatic reactions and was herein applied t

228 rein applied to investigate the influence of crowding on phosphoglycerate mutase in Escherichia coli,

229 pleted to determine the effects of molecular crowding on RNA duplexes of varying lengths and sequence

230 Here, we investigate the influence of crowding on the interaction between two IDPs that fold u

231 is known about the effect of macromolecular crowding on the interactions of IDPs with their cellular

232 tic changes in organellar volume, leading to crowding on the micrometer scale, which we term organell

233 ported significant effects of macromolecular crowding on the structure and behavior of biomolecules.

234 The effect of molecular crowding on the structure and function of Escherichia co

235 al acuity, hyperopia, short axial length and crowded optic discs.

236 ggregate, rather than through macromolecular crowding or diffusion-limitations.

237 eraction, or by the global environment (e.g. crowding or phase separation).

238 f electricity markets and a limited role for crowd out effects.

239 sibility, which objectively demonstrates the crowding out of professional mainstream sources by the p

240 bon innovation of ETS firms by 5-10% without crowding out their other technology innovation.

241 We show that self-reliance crowds out cooperation and exacerbates inequality, espec

242 exyl phthalate metabolites [p=0.014]), house crowding (p=0.015), and facility density around schools

243 e proposed multi-ball model can achieve more crowded packaging results and contains richer elements w

244 as well as quenching dye-dye interactions on crowded particle surfaces.

245 nates from the entropic effect caused by the crowding particles in the system.

246 In crowding, perception of an object deteriorates in the pr

247 ectron microscopy, but their location in the crowded perinuclear area has hampered their analysis via

248 disproportionate incarceration of BIPOC into crowded prisons with low tuberculosis screening rates; a

249 o observe the motion of IFT proteins in this crowded region using conventional microscopy.

250 an age-dependent increase in macromolecular crowding resulting from water loss may be responsible fo

251 sponds to changes in hydration and molecular crowding, revealing an unexpected mode of globally progr

252 We suggest that conventional crowding rules only hold when target and flankers are ar

253 's schooling, number of goods, and household crowding), self-esteem, oral health beliefs, and frequen

254 n our approach, each query is regarded as a "crowd sensor" with a certain weight of confidence to pro

255 Using a macromolecular crowding sensor optimized for long-term FRET measurement

256 or one feature and strong for the other that crowding should be all-or-none for both.

257 es indicates that alcohol attack to the more crowded side of the acyl-catalyst intermediate is favour

258 driven by 3 symptomatic persons who attended crowded social events.

259 viral origin are upregulated in response to crowding solely in highly inducible genotypes.

260 forces that push macromolecules together in crowded solutions and thus promotes aggregation and phas

261 n genetics, we developed high-throughput and crowd-sourced approaches focused on question-asking beha

262 se the opportunistic sampling process of the crowd-sourced data and assess its sampling bias.

263 Using crowd-sourced data from the Amazon Kindle application, w

264 The analysis has been conducted using the crowd-sourced Heart for Heart data.

265 We crowd-sourced primatologists and found a strong linear r

266 ssible populations, such as laboratories and crowd-sourced worker platforms, are not always replicate

267 We used a crowd-sourced, citizen science approach to analyze imagi

268 d from governmental reports, as well as from crowd-sourcing data, based on Twitter messages and local

269 ed through Amazon Mechanical Turk, an online crowd-sourcing marketplace.

270 Using crowd-sourcing, this initiative is a step towards unders

271 10(5) M(-1) s(-1)) for esters with the least crowded space around their carbonyl group.

272 However, due to the compact and crowded status, the missing edge effect, and low signal

273 We describe in detail the crowding, sticking, and quinary structure in the cell an

274 ery conditions and in response to an applied crowding stressor.

275 nts, and TF-gene co-occurrence computed from crowd-submitted gene lists.

276 is suppressed in the present sterically very crowded system, N(2)-to-NH(3) conversion can nevertheles

277 ion between the two IDPs is less enhanced by crowding than expected for folded proteins of the same s

278 les, tens to hundreds of nanometers in size, crowd the eukaryotic cytoplasm.

279 eripheral vision is fundamentally limited by crowding, the deleterious effect of clutter that disrupt

280 19) show how the nematode C. elegans detects crowding to change feeding behavior by coupling pheromon

281 nfinement like those experienced by cells in crowded tumors.

282 By enhancing intracellular crowding using osmotic and mechanical compression, we sh

283 Intracellular crowding varies upon stimulation by different types of e

284 Risk of crowding was independent of the population at the landin

285 The multiplicity of crowding was then tested with observers identifying both

286 In contrast, when crowding was weak for color and strong for motion, error

287 Finally, the effects of crowding were explored in the context of a linear pathwa

288 ia is prone to apoptotic cell extrusion upon crowding, whereas the pendant counterpart favors live ce

289 Capitalising on the concept of "wisdom of crowds", which states that a group's collective judgemen

290 we can reliably replicate measures of visual crowding, which depends on a precise calculation of visu

291 osts on reporting extreme scores can improve crowd wisdom in a previously cost-free rating system.

292 vidual biological molecules in the molecular crowd with high specificity and accuracy, uncovering uni

293 ntain a large variety of lipid types and are crowded with proteins, endowing them with the plasticity

294 network architecture resisted macromolecular crowding with polyethylene glycol and blocked ATP-powere

295 transcription kinetics and presents dynamic crowding within the bulk nuclear nanoenvironment as a no

296 Experimentally, increasing crowding within the compact layer cardiomyocytes augment

297 lion cells (RGCs) underlying Ricco's area or crowding zone is estimated by computing the product of R

298 by computing the product of Ricco's area (or crowding zone) and RGC density for a given target locati

299 ction (Ricco's area) and object recognition (crowding zone) are measured at various target locations.

300 sequently been interpreted as a link between crowding zones, receptive field scaling, and our percept