ライフサイエンスコーパス: crucial

1 r, careful selection of suitable patients is crucial.

2 circuit voltage, interfacial layers are also crucial.

3 1 assembly assays with purified proteins are crucial advances for antiviral targeting of influenza vi

4 methane via dry reforming is environmentally crucial and for the chemical industry as well.

5 derstanding of the unique characteristics is crucial and lifesaving treatments must be made widely av

6 ummarizes key features of the guideline in 7 crucial areas: targeting of statin dose (not low-density

7 Identifying the exact cause of HLH is crucial, as definitive treatment for primary disease is

8 ng which may arise in such data and become a crucial aspect for determining classification performanc

9 A crucial aspect when learning a language is discovering t

10 Consequently, some crucial aspects of available biological knowledge may ge

11 This is crucial because the different cortical layers have disti

12 ogical synapses which facilitate exchange of crucial biochemical information and are critical for T-c

13 rowth factor receptor-2 (HER2) are the three crucial biomarkers for the clinical diagnosis of breast

14 nutrients from the surface ocean provides a crucial but seasonally variable energy source to seafloo

15 This work reports crucial cellular crosstalk during lung development invol

16 th the advent of quantum technology, it is a crucial challenge to design quantum neural networks for

17 uction from water represents one of the most crucial challenges to produce renewable fuel.

18 rate that the CCCTC-binding factor (CTCF), a crucial chromatin organizer, is essential for Schwann ce

19 The OX40-OX40L pathway provides crucial co-stimulatory signals for CD4 T cell responses,

20 Polarization is a crucial component in cell differentiation, development,

21 ed in bioelectronic applications have been a crucial component of many recent discoveries.

22 Glomerular endothelial cells (GEC) are a crucial component of the glomerular physiology and their

23 this mitochondrial mild depolarization is a crucial component of the mitochondrial anti-aging system

24 puzzle to which cytogenetics has contributed crucial data.

25 Crucial decisions involving cell fate and connectivity t

26 glutathione (GSH), which constitute the most crucial defense system that protects cells from therapeu

27 y that the trafficking protein SNX1 may be a crucial determinant for hypertension and response to ant

28 ding receptor Neuropilin-1 (Nrp-1) emerge as crucial determinants of MCMV infection.

29 g to the plane of the core quinoline to be a crucial determinate of PAM activity.

30 k reveals an endogenous signal that triggers crucial developmental processes in filamentous fungi, an

31 imple quantitation of microRNAs are becoming crucial enablers of early diagnosis and therapeutic foll

32 dopsis, DNA polymerase theta (PolQ) may be a crucial enzyme involved in T-DNA integration.

33 o reprogram histone methylation during three crucial epigenetic reprogramming windows: maternal repro

34 dies are providing new insights into how two crucial families of the TrxG - the COMPASS family of his

35 structural organization of chromosomes is a crucial feature that defines the functional state of gen

36 These crucial findings provide the correct anthocyanin profile

37 of gene-level abundances for each cell is a crucial first step in most dscRNA-seq analyses.

38 ule-specific glycosylation features and is a crucial first step toward a better understanding of the

39 Artemisinin and its derivatives (ART) are crucial first-line antimalarial drugs that rapidly clear

40 2) oxidation on the anodic membrane side, is crucial for (1)O(2) generation.

41 sphorylation of Thr(17) by CaMKII may become crucial for 14-3-3 recruitment to DeltaArg(14) PLN.

42 nically induced transparency and absorption, crucial for a number of applications including sensitive

43 Efficacy evaluation through human trials is crucial for advancing a vaccine candidate to clinics.

44 ells (WBCs) in the pulmonary vascular bed is crucial for an effective immune response.

45 tial patterns in future population levels is crucial for anticipating and planning for changing age s

46 or donor stem/progenitor cell populations is crucial for augmenting the low intrinsic repair potentia

47 sidue within the Aurora A activation loop is crucial for Aurora A activation by autophosphorylation.

48 The rate of cell growth is crucial for bacterial fitness and drives the allocation

49 ptation to reactive oxygen species (ROS) are crucial for cell survival.

50 heterotrimeric transcription factor NF-Y is crucial for cell-cycle progression in various types of c

51 dynamic organelle whose correct assembly is crucial for cellular homeostasis.

52 (+)-ATPase-mediated endosomal acidification, crucial for ClC-5 activation by depolarizing endosomes.

53 ilizers of O(2)-bound intermediates are more crucial for cobalt porphyrin ORR catalysts.

54 ecific O-glycosylation on single proteins is crucial for comprehensive characterization of some impor

55 prepacked foods, because this information is crucial for consumers and food policy-makers as well as

56 mbryos, SEIP-1 is associated with LDs and is crucial for controlling LD size and lipid homeostasis.

57 hin a narrow window is widely regarded to be crucial for cortical processing.

58 Determining the site of cell cleavage is crucial for cytokinesis and involves precise activation

59 Nrf2 transcription factor is crucial for cytoprotective response, whereas Keap1-an en

60 stress that identifying dominant drivers is crucial for designing efficient mitigation policies.

61 he 5' structure-specific nuclease family are crucial for DNA repair, replication, and recombination.

62 Standardized gene naming is crucial for effective communication about genes, and as

63 und within the tumor myeloid compartment are crucial for effector T cell recruitment to the tumor mic

64 pus is a part of the mammalian brain that is crucial for episodic memories.

65 Paneth cells (PCs) are crucial for epithelial immune defense and highly vulnera

66 We therefore propose that RLCs are crucial for fine-tuning the myosin function.

67 Patient-individual restoration of offset is crucial for free ROM in THA.

68 Binding of ligands is often crucial for function yet the effects of ligand binding o

69 oside PTS transporter (bglP) was found to be crucial for GAS growth and survival in human blood and w

70 lper (TFH) cells provide B-cell help and are crucial for generating long-term humoral immunity.

71 Metabolic fitness of T cells is crucial for immune responses against infections and tumo

72 ns cooperate to drive leukemogenesis will be crucial for improving diagnostic and therapeutic options

73 etecting rapid visual field deterioration is crucial for individuals with glaucoma.

74 ANCE CD40-CD40 ligand (CD40L) interaction is crucial for inducing effective cytotoxic and humoral res

75 dentify 4 of 413 residues from TrpB that are crucial for its allosteric activation by TrpA.

76 However, it is crucial for many biological applications such as the des

77 It is crucial for many tasks, from object recognition to tool

78 These data demonstrate that IQGAP1 is crucial for metastasis in vivo through regulation of ext

79 ession of DeltaNp63 in established tumors is crucial for metastatic dissemination in breast cancer.

80 sugars, is a unique property of life that is crucial for molecular recognition, enzymatic function, i

81 Mechanosensitive ion channels are crucial for normal cell function and facilitate physiolo

82 Dosage of imprinted genes is crucial for normal development and its dysregulation acc

83 Here, we identify a novel mechanism that is crucial for normal ER lipid metabolism and protects the

84 ght asymmetric shapes and positions that are crucial for normal function.

85 port, we demonstrate that endogenous Amot is crucial for positively regulating egress of eVP40 virus-

86 ufficient microperfusion of the allograft is crucial for postoperative organ function.

87 epidemiological parameter estimates that are crucial for practical management of epidemics and predic

88 an on-and-off "burst" of ClC-5 activity was crucial for preventing Cl(-) exit from endosomes.

89 elopment of novel and efficient catalysts is crucial for progress in chemical sciences, and this expl

90 ions in distinct tissue environments and are crucial for protection against helminth infections and f

91 r, a pentameric ligand-gated ion channel, is crucial for regulating conductance.

92 onse to S. aureus Given that neutrophils are crucial for S. aureus clearance, understanding the mecha

93 ion of residues 527, 528, and 530, which are crucial for S1P cleavage.

94 Phase separation is crucial for selective surfactant formation as well as au

95 h gene conversion and contain genes that are crucial for sexual reproduction.

96 ll (DW) dynamics along magnetic nanowires is crucial for spintronic applications.

97 ydroxyl group of the ligating acetic acid is crucial for stabilization of the palladacyclic intermedi

98 the phagosomal surface inside macrophage is crucial for survival and virulence of M. tuberculosis ES

99 ssion of actions to avoid aversive events is crucial for survival.

100 expression in the central nervous system is crucial for T cell recruitment and reactivation into a p

101 temporal epoch of SC visual activity that is crucial for the ability of mice to detect behaviorally r

102 he signaling protein Sonic Hedgehog (SHH) is crucial for the development and function of many vertebr

103 particularly interesting since simplicity is crucial for the development of ECG-based ambulatory syst

104 tic approach to identify amino acid residues crucial for the expression and stability of FXIII-A2.

105 These molecular changes could be crucial for the function of the protein, as evidenced by

106 ed perioperative care for HF subtypes may be crucial for the growing population of HF patients underg

107 ed by colonization of the gut microbiota, is crucial for the prevention of CDI in human microbiota-as

108 Bipolarity of the spindle is crucial for the proper cell division, and two centrosome

109 ng partner of the tumor suppressor BRCA1, is crucial for the repair of DNA interstrand crosslinks (IC

110 g RNA ephemeron, whose rapid upregulation is crucial for the transition of ESCs into epiblast, and th

111 l social relations, such as friendships, are crucial for the well-being and success of students at al

112 compared to human ANP32A proteins, which are crucial for their ability to support the avian-origin in

113 nal content of functional HS motifs which is crucial for their future biomedical exploitation.

114 uently, structural analysis of antibodies is crucial for therapeutic development.

115 adium acetate [Pd(3)(OAc)(6)] is found to be crucial for these catalytic pathways.

116 iduals and between different tissues will be crucial for treating diseases in which type 2 immunity i

117 s and connections supporting this control is crucial for understanding both the nature of computation

118 nsible and the features of this activity are crucial for understanding how spontaneous activity influ

119 Our findings are crucial for understanding how the brain regulates inform

120 s (nAbs) elicited by SARS-CoV-2 infection is crucial for understanding immune protection and identify

121 l distributions of biomolecules in tissue is crucial for understanding integrated function.

122 Thermodynamic characterization is crucial for understanding molecular interactions.

123 eover, the preparation of smooth surfaces is crucial for vertically stacked devices and, hence, the d

124 Insulin action in adipose tissue is crucial for whole-body glucose homeostasis, with insulin

125 c modulation at the wavelength scale paves a crucial foundation for realizing large-scale LN photonic

126 data support a model in which SNAP23 plays a crucial function as a scaffold for ATG16L1 necessary for

127 Studies in recent years have uncovered the crucial function of neuroimmune interactions in maintain

128 NCE STATEMENT The hippocampal formation is a crucial functional substrate for episodic memory and spa

129 stable isotope-labelled internal standard is crucial, given the diversity of encountered food matrice

130 ty of intermediate signaling molecules are a crucial hijacking point for a successful viral pathogene

131 nts of the ganglioside synthetic pathway are crucial host factors that are required for cellular entr

132 d to the external microenvironment, mediates crucial host-parasite interactions.

133 change mechanisms and dynamics, which have a crucial impact on determining the copolymer microstructu

134 These outcomes have a crucial impact on the course of the intellectual battle

135 lopropanone precursors, were found to have a crucial impact on the rate of equilibration to the corre

136 apts to different thermal environments is of crucial importance, especially in the face of global cli

137 catalysis of electrochemical reactions is of crucial importance.

138 eral mouse models of stress, which have been crucial in developing a greater understanding of interge

139 flowing and coagulated blood (thrombus) are crucial in dictating the deformation and remodeling of a

140 Long noncoding RNAs (lncRNAs) are crucial in many cellular processes, yet relatively few h

141 plementation of evidence-based guidelines is crucial in optimising intervention use and improving qua

142 texts, the nonenzymatic effects of HYAL2 are crucial in orchestrating RhoA signaling and downstream p

143 hibiting principal neurons) connections, are crucial in processing sensory information.

144 itial trigger for insulin signaling, that is crucial in regulating downstream signaling and glucose u

145 ncentration of SARS-CoV-2 S1-specific IgG is crucial in selecting appropriate convalescent serum dono

146 ect and continuous monitoring of propofol is crucial in the development of automatic systems for cont

147 the hallmarks of aging in the liver will be crucial in the development of preventive measures and tr

148 Appropriate drug selection remains crucial in this evolving landscape to derive maximum ben

149 We observed elevated expression of crucial injury response factors-including kidney injury

150 iterature applying these techniques to yield crucial insights into battery operation and performance.

151 ur high-treatment experiment also identified crucial interactions between nanoplastics and climate ch

152 lesions of KC mouse pancreas reinforces the crucial involvement of MUC5AC in bolstering the CSC-asso

153 Thus, a two-compartment model with five crucial ionic currents in the apical dendrites reproduce

154 bond-forming reactions, these have numerous crucial limitations, especially for industrial-scale app

155 Finally, we identify POSH as a crucial link that bridges cytosolic Ca(2+) alteration wi

156 Regulatory T cells (Tregs) are crucial mediators of immune homeostasis.

157 ced the availability of luminal succinate, a crucial metabolite for the growth of C. difficile, and t

158 MAOB, a crucial monoamine oxidase for dopamine metabolism, trigg

159 The crucial next steps towards using single rare-earth ions

160 pathogenesis and that histidine serves as a crucial nitrogen source during infection.

161 Blood pressure (BP) management is a crucial part of critical care that directly affects morb

162 The crucial part of this strategy is expression of a broad f

163 n patients with corneal diseases, which is a crucial part of visual rehabilitation.

164 ymes, lignin degradation and cell growth are crucial phenotypes of lignin-utilizing bacteria, but the

165 of genes governing the biosynthesis of these crucial phenotypic traits that have greatly impacted ins

166 s been maintained within coding sequences of crucial plant and animal genes.

167 has gained recognition as a key regulator of crucial processes such as protein turnover, protein-prot

168 ous work in this direction by addressing the crucial question of identifying the processes which act

169 of microRNA-induced silencing complex) as a crucial regulator in hypoxia-induced angiogenesis.

170 lammation and pathogen control, as well as a crucial regulator of a growing number of tissue-resident

171 growth factor like growth factor (HB-EGF), a crucial regulator of heart valve development in mice.

172 cent findings highlight cell metabolism as a crucial regulator of these processes.

173 These findings established TRIM28 as a crucial regulator of VEGFR-Notch signaling circuit throu

174 des an extraordinary opportunity to pinpoint crucial regulators and target genes responsible for comp

175 itochondrion and its associated proteins are crucial regulators of these responses and related pathwa

176 Our observations urge a crucial revisit of various experimental findings and the

177 l cells at the time of implantation, plays a crucial role during early pregnancy.

178 ning emissions over the northwest IGP play a crucial role during post-monsoon.

179 ption factors of the NF-kappaB family play a crucial role for immune responses by activating the expr

180 This mechanism has a crucial role in Birt-Hogg-Dube syndrome, a disorder that

181 The caecal microbiota plays a crucial role in chicken nutrition through the production

182 indicating that evolutionary history plays a crucial role in determining an organism's composition.

183 y, and cognitive skills specifically, play a crucial role in determining economic mobility and macroe

184 -of-care (POC) immunodiagnostic tests play a crucial role in enabling rapid and correct diagnosis of

185 Magnetotail reconnection plays a crucial role in explosive energy conversion in geospace.

186 duct A-type intercalated cells, and plays a crucial role in hypertension, cardiovascular disease, ki

187 Plant stomata play a crucial role in leaf function, controlling water transpi

188 Stewardship will have a crucial role in limiting unnecessary antimicrobial use a

189 evidence indicates that SUMOylation plays a crucial role in maintaining and regulating neural functi

190 ATR plays a crucial role in maintaining genomic integrity by respond

191 VGCCs are multisubunit complexes that play a crucial role in neuronal signaling.

192 This process plays a crucial role in organ development and repair, in wound h

193 eported that placental lactogen (PL) plays a crucial role in pregnancy-induced maternal beta-cell pro

194 ) is active in capillaries, where it plays a crucial role in preventing dyslipidemia by hydrolyzing t

195 lls, specifically gammadelta T cells, have a crucial role in promoting sympathetic innervation, at le

196 elet-derived growth factor B (PDGFB) plays a crucial role in recruitment of PDGF receptor beta-positi

197 le C-terminal tails of Mtf1 and TFB2M play a crucial role in RNA priming by aiding template strand al

198 by cultural and social factors, which play a crucial role in the determination of handedness.

199 wine influenza A viruses (swIAVs) can play a crucial role in the generation of new human pandemic vir

200 addition, CD4(+) T cells and HLA-DQ8 have a crucial role in the licensing of cytotoxic T cells to me

201 adation of intracellular components, plays a crucial role in the maintenance and genetic integrity of

202 Toll-like receptors (TLRs) have a crucial role in the recognition of pathogens and initiat

203 nic fat cells (brown adipocytes) that play a crucial role in the regulation of energy metabolism and

204 resent data reveal that EVs from MRSA play a crucial role in the survival of beta-lactam susceptible

205 STEC activity, suggesting that SubAB plays a crucial role in the survival of LEE-negative STEC as wel

206 dditionally demonstrate that NO might have a crucial role in these responses.

207 f region of difference 1, is known to play a crucial role in virulence and pathogenesis of M. tubercu

208 patients with solid tumors and highlight the crucial role of a 3-D environment for testing NK cell fu

209 First, we validated the crucial role of active STAT5 as a survival factor for fu

210 three-dimensional simulations highlight the crucial role of actomyosin contractility, which is requi

211 on spectroscopy, our strategy highlights the crucial role of BLG hydrophobic cavity and opens up new

212 ic studies were performed to demonstrate the crucial role of boron catalyst for the activation of the

213 The crucial role of mtCa(2+) in tumorigenesis is highlighted

214 se models for prostate cancer to support the crucial role of Sox2 is missing.

215 However, our findings about the crucial role of the anterior insula for ipsilateral affe

216 Second, we demonstrate the crucial role of the DNA vaccine in soluble factors relea

217 nctional theory (DFT) simulations unveil the crucial role of the initial reversible C-C single bond f

218 lysis of the MvcA-UBE2N-Ub complex reveals a crucial role of the insertion domain in MvcA in substrat

219 Mechanistic studies point to the crucial role of the photocatalyst-base interaction.

220 endicular magnetic anisotropy, which plays a crucial role on thermal stability and critical writing c

221 In sum, our findings highlight the crucial role played by lamin-chromatin and lamin-cytoske

222 In contrast with the crucial role played by the TPR domain of OXA2b, the TPR

223 es for experimentation, modelling can play a crucial role.

224 Quorum sensing plays crucial roles in bacterial communication including in th

225 cer stem cells (CSCs) or CSC-like cells play crucial roles in cancer metastasis and are exceptionally

226 Consequently, EPKs play crucial roles in cell differentiation and cell-cycle pro

227 Tubulins play crucial roles in cell division, intracellular traffic, a

228 Receptor tyrosine kinases (RTKs) play crucial roles in human health, and their misregulation i

229 regulating the expression of genes that play crucial roles in microglial phagocytosis.

230 quintuple and sextuple mutants confirmed the crucial roles of ALA proteins in regulating plant develo

231 Our data provide evidence on the crucial roles of OsJAZ9 for improving K deficiency toler

232 rt the experimental data and demonstrate the crucial roles of the trans-geometry of the [H-Pd(L)-Ge]

233 Given these crucial roles, mGluR5 signaling is under the tight contr

234 tand SARS-CoV-2 infection and (2) conducting crucial serology field studies to advance an understandi

235 ur data suggest that C-terminal tails harbor crucial signals for both the insertion and assembly of m

236 Pathogen-derived nucleic acids are crucial signals for innate immunity.

237 However, the crucial source of CD73 activity within the tumor microen

238 hanism of hGBP1 polymer formation as it is a crucial state of this enzyme, allowing for a rapid respo

239 ower to detect statistical significance is a crucial step at the design stage for high-throughput exp

240 ion levels across nesting sites worldwide, a crucial step in assessing the impact of climate change o

241 chanisms that drive aortic degeneration is a crucial step in developing an effective pharmacologic tr

242 e their photodissociation back to Hg(0) as a crucial step in the atmospheric Hg redox cycle.

243 atory cells and endothelial cells (ECs) is a crucial step in vascular inflammation.

244 Our findings represent a crucial step toward translational genetics, from highlig

245 mRNA, and translation factors) and regulates crucial steps in protein synthesis.

246 the progression of prostate cancer and is a crucial target for therapeutic interventions.

247 Although uncommon, HL remains a crucial test case for progress in cancer treatment.

248 Thus, it is crucial that future studies take into consideration the

249 in engagement at the plasma membrane (PM) is crucial to a broad range of cellular functions, includin

250 Optimizing the nitrogen (N) input is crucial to achieving desirable biomass production of PCG

251 ctive tools for viral load monitoring become crucial to allow specific diagnostics and the effective

252 The correct diagnosis is crucial to allow the consideration of all possible manag

253 Social behaviors are ubiquitous and crucial to an animal's survival and success.

254 he hyperacute stage of vascular occlusion is crucial to assess the role of inflammation in human stro

255 way into clinical radiology practice, it is crucial to assure that they function correctly and that

256 id homeostasis despite these fluctuations is crucial to cell function and viability.

257 g-related behavior and energy expenditure is crucial to combating obesity and its comorbidities.

258 c POMs with organic and inorganic cations is crucial to control POM self-assembly, stabilization, sol

259 ence showing that technological reasoning is crucial to cumulative technological culture but it fails

260 Heterogeneity characterization is crucial to define the quality of end products and to des

261 l temperature variation in their habitats is crucial to determining vulnerability to global warming.

262 Hence, it is crucial to develop effective approaches for monitoring i

263 cognition and are altered during old age is crucial to develop preventive or therapeutic strategies.

264 erstanding the drivers of this bottleneck is crucial to developing effective infection control strate

265 among people who inject drugs (PWID), it is crucial to effectively scale-up opioid agonist therapy (

266 EMT is crucial to embryonic development and wound healing.

267 g step changes in genetic yield potential is crucial to ensure food security, but efforts are thwarte

268 allergenicity of new or modified proteins is crucial to ensure public health protection.

269 ular endothelial growth factor-A (Vegf-A) is crucial to establishing NMJ reinnervation at the end tar

270 ut our analysis demonstrates that it will be crucial to evaluate the accuracy of such models critical

271 ) is becoming available, and therefore it is crucial to identify eligible candidates.

272 In that case, it will be crucial to identify the mechanism of breakthrough infect

273 To improve their performance, it is crucial to identify the most active sites.

274 onse and of the pathogenesis of infection is crucial to identify valid therapeutic tools to control v

275 le our results demonstrated that DMS will be crucial to improve variant effect prediction methods, da

276 understanding of the pathogenesis of SFTS is crucial to improving medical countermeasures against thi

277 the unsaturated spiroketal fragment might be crucial to induce PP2A inhibition.

278 hagy is an intracellular degradation pathway crucial to maintaining cellular homeostasis by clearing

279 tanding how such complex structures arose is crucial to our understanding of cellular evolution.

280 tection of animal species in meat product is crucial to prevent adulterated and unnecessary contamina

281 ion responses to changes in rainfall is thus crucial to project water and carbon cycles in the future

282 aintaining life-long health behaviors may be crucial to reduce late-life risk of dementia.

283 standing how their synthesis is regulated is crucial to revealing these lipids' role in health and di

284 in antibiotic stewardship program efforts is crucial to sustain the efficacy of antibiotics and quali

285 drogen production from water electrolysis is crucial to the deployment of sustainable hydrogen econom

286 Major corticofugal tracts are crucial to the onset and progression of amyotrophic late

287 art of the 7SK ribonucleoprotein complex, is crucial to the regulation of transcription by RNA-polyme

288 ic reactions in biological systems, which is crucial to understand homeostatic alterations with disea

289 ents were expressed in local environments is crucial to understand human and animal survival.

290 ory corollaries of motor control thus can be crucial to understand sensory sensation and perception u

291 ary specialization and niche partitioning is crucial to understanding the maintenance of biodiversity

292 n of salts in water at extreme conditions is crucial to understanding the properties of aqueous fluid

293 Activities crucial to vision occur within the IPM, including traffi

294 It is crucial to visualize these molecular-interaction complex

295 der elephant society through loss of leaders crucial to younger male navigation in unknown, risky env

296 Crucial transitions in cancer-including tumor initiation

297 Crucial understandings gained from early rollout among a

298 unraveling of the molecular aspects of these crucial virus-host interactions will continue to enhance

299 tochondrial dysfunction was highlighted as a crucial vulnerability factor for the development of depr

300 ly future impacts of biological invasions is crucial yet highly challenging given the multiple releva