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1                                              Crucially, 3 bp overhangs corresponding to start and sto
2                                              Crucially, a classifier trained to decode high versus lo
3 ing enzymes, complement, immunoglobulins and crucially, a range of anti-viral and pro-inflammatory cy
4                                         More crucially, a simple polymer:solvent interaction paramete
5                                              Crucially, a single dose of 10-del ZIKV induced steriliz
6 to-equilibrium with increased daylength and, crucially, a threshold daylength above which interaction
7                                              Crucially, abolishing cell cycle asynchrony consistently
8                                              Crucially, across 52 brain-wide anatomical features, cer
9 e role of non-native intermediates which may crucially affect organismal fitness and are frequently i
10                         These pilus dynamics crucially affect the local order, shape, and fluidity of
11 c proximity, and social closeness, which may crucially affect the outcome of interactions.
12 e migration of species across interfaces can crucially affect the performance of heterogeneous cataly
13  number of available workers to the workload crucially affects performance.
14 k in tasks they are not currently engaged in crucially affects whether task allocation is quickly ach
15                                              Crucially, all sub-measurements are reported, and no dat
16 akened some measures of sexual selection and crucially also impacted sexual selection indirectly by c
17 n of their respective molecular targets, but crucially also revealed system-wide neural circuit respo
18 rozoite egress and erythrocyte invasion, but crucially, also blocks transmission of mature P. falcipa
19                                              Crucially, among anti-PD-1-treated patients with metasta
20              Receptor density is shown to be crucially and nonlinearly correlated to complex formatio
21                                              Crucially, animal behavior in natural settings implies t
22                                              Crucially, anodal stimulation to the rTPJ increased the
23 matized lithospheric mantle and plumes) and, crucially, are found throughout the geological record.
24 des in the endosomal-like compartment and is crucially associated to rhoptry discharge during invasio
25                                              Crucially, before watching the last part of each activit
26                                              Crucially, BLA-damaged subjects, unlike control subjects
27                                              Crucially, calcium plays a fundamental role in stabilizi
28 n be driven by mitochondrial dysfunction and crucially can occur independently of cell division and t
29                                              Crucially, carnosine also reverses glucolipotoxic inhibi
30                                              Crucially, chemical inhibition of NorA effectively preve
31                                              Crucially, cingulo-frontal connectivity was a common loc
32                                              Crucially, clearance of senescent melanocytes using the
33                                              Crucially, clinical gains continued during the 6-month f
34 CD55), a complement C3 convertase regulator, crucially controls disease in murine models of adriamyci
35                                              Crucially, cross-prediction showed that mean reward and
36                                              Crucially, current models underestimate the predictable
37 ates than those in urban control broods; and crucially (d) urban supplemented broods had similar body
38           Curvature of the graphenic lattice crucially defines the direction of permeation from conca
39 lation, and functionally engineered rheology crucially depend on microparticles and microfibers with
40 hat, the generated non-locality correlations crucially depend on the decay and the initial coherence
41 -angle twisted bilayer graphene (MATBG)(1,2) crucially depend on the interlayer twist angle, theta.
42 s suggest that all measurable quantities may crucially depend on the nature of normalization.
43 t ecosystem impacts of heavy rainfall events crucially depend on the seasonal timing and multiannual
44 ctronic properties of oxide heterointerfaces crucially depend on their ionic constitution and defect
45 ent of near-term targeted therapeutics could crucially depend on thoughtful design of rigorous presym
46 e observed that the impact of the D1 agonist crucially depended on baseline working memory functionin
47   MPM development spanned across decades and crucially depended on the concurrent improvement of calc
48                         Functional remapping crucially depended on top-down feedback as chemogenetic
49 rrelate with antibody polyreactivity but was crucially dependent on the accumulation of somatic mutat
50 ct network, which makes the epidemic process crucially dependent on the network structure.
51 model, we reveal that fAbeta accumulation is crucially dependent on the regulation of the sleep-wake
52  demonstrate that centriole amplification is crucially dependent on these organizing centres and that
53 (FH)s and germinal center (GC) response were crucially dependent on TSLP in both the MC903 model and
54 plate in methylcellulose culture, a property crucially dependent upon ABCC4.
55  by the environmental context but is instead crucially dependent upon it.
56 gement of patients with aortic stenosis (AS) crucially depends on accurate diagnosis.
57  brain disorder at all, even when the former crucially depends on aspects of brain structure.
58                           Adaptive behaviour crucially depends on flexible decision-making, which in
59                      Oxygenic photosynthesis crucially depends on proteins that possess Fe(2+) or Fe/
60 igand design for G protein-coupled receptors crucially depends on receptor conformation and, hence, t
61                         Memory consolidation crucially depends on sharp-wave ripples (SWRs), which ar
62 rformance and the robustness of improvements crucially depends on the availability of sufficiently la
63               The feasibility of elimination crucially depends on the effects of multiple ivermectin
64               Signaling through this pathway crucially depends on the opposing activities of two cyto
65 tures, such as luminosity or magnetic field, crucially depends on the poorly known heat and charge tr
66                          Sexual reproduction crucially depends on the production of sperm in males an
67                  Stabilization of the latter crucially depends on the steric protection by the t-Bu g
68 uantification of miRNA expression by qRT-PCR crucially depends on validated housekeepers for data nor
69                                              Crucially, depletion of KHNYN eliminated the deleterious
70 ithin the globular domain of histone H4 that crucially determine genome organization and expression i
71 em that produces error signals appears to be crucially determined by the personal relevance of the in
72                    This subunit organization crucially determines the physiological and pharmacologic
73                                              Crucially, different conditions are configurable allowin
74                              The latter also crucially directs the molecular packing in the solid.
75                                              Crucially, distractor learning benefits were observed wi
76                                              Crucially, drug discovery campaigns focusing on SHP2 wou
77                                              Crucially, drug levels are predictive of response 6 mont
78                                              Crucially, emerging evidence shows specific adaptations
79                                              Crucially, endorsed social harms accounted for explained
80 he development of many organs and is further crucially engaged in pathophysiological processes underl
81                                              Crucially, ER heterogeneity of differentiation genes is
82                                              Crucially, excellent properties are also demonstrated at
83                                              Crucially, glutamate concentration correlated negatively
84 terns, the strong specificity of which might crucially help establish or eliminate the diagnosis of P
85                                 1), what may crucially help groups of individuals cohere and prevail
86                                              Crucially, however, each band also exhibited temporally
87                                              Crucially, however, high EPT followers were better able
88                                              Crucially, however, the interplay between these two forc
89                                              Crucially, however, value type moderates whether person-
90                                              Crucially, however, we measured an interaction between M
91 an rhythms in bipolar patient cell lines and crucially if lithium's effect on the clock is fundamenta
92 rks of type-II phase oscillators and, hence, crucially impacts on the overall hierarchical connectivi
93                        Young researchers are crucially important for basic science as they make unexp
94 he orientation of the 20 carbon epimer being crucially important for biological activity.
95 ying material properties at the nanoscale is crucially important for devices in nano-electronics, nan
96 small molecule ligands to protein targets is crucially important for drug discovery.
97 h metrics ignore regulatory signals that are crucially important for optimal pathway operation, for i
98 hetic activity of aquatic micro-organisms is crucially important for understanding the environmental
99 formed at the interface whose properties are crucially important in samples with a thickness of YIG l
100   Lattice degrees of freedom are found to be crucially important in stabilizing the various phases.
101  glycine and one-carbon pathway (SGOCP) is a crucially important metabolic network for tumorigenesis,
102 ness of resistant strains were identified as crucially important parameters.
103 cues the muscle from atrophy, which are both crucially important since in most cases OPMD patients al
104 on of bacterial genomes is an obligatory and crucially important step of information processing from
105 horough review of the existing literature is crucially important to drive new research.
106  278 ancient horses finds that this animal - crucially important to many ancient and contemporary hum
107                            Such insights are crucially important with regard to developing the next g
108 ns persist and respond to changes has become crucially important.
109  high yields on N-deficient soils has become crucially important.
110 gh-efficiency telescope and follow-up optics crucially improved the link efficiency.
111  encapsulation of OR and TCA within micelles crucially improved their antibacterial activity.
112  cord before symptom onset in SBMA mice, and crucially in motor neuron precursor cells derived from S
113  similar experimental paradigms, they differ crucially in their notion of the stimulus-driven periodi
114                                              Crucially, in both age groups, a more responsive noradre
115                                              Crucially, in both cohorts, dynamic time-varying measure
116                                              Crucially, in both demonstration conditions some childre
117 ial step in avoiding off-target effects and, crucially, in developing new anti-inflammatory strategie
118 of FUS in both VCP-mutation related ALS and, crucially, in sporadic ALS spinal cord tissue from multi
119                                              Crucially, in the activated endothelial (HMEC-1) cell as
120                                              Crucially, in the opposite low-data/deep limit, although
121 ypical inanimate objects (e.g., a mug), and, crucially, inanimate objects that look like the animate
122 inity through reducing root-soil contact and crucially increasing porosity at the root-soil interface
123 ark coloration generally, temperature should crucially influence the costs, benefits and geographic d
124 on and passive cellular force response, both crucially influenced by the actin cytoskeleton.
125 cally removed from around the target protein crucially influences LO decisions.
126                             Physical fatigue crucially influences our decisions to partake in effortf
127                                              Crucially, informed by the spatial correspondence cues a
128                                              Crucially, introduction of any of the modified residues
129 other being vinylcyclopentadienyl, a species crucially involved in a recently proposed mechanism of s
130  led to the identification of PCSK6 as being crucially involved in cardiac remodeling after acute myo
131 , programmed cell death, and survival and is crucially involved in inflammation, autoimmune disorders
132                    Peroxiredoxins (Prxs) are crucially involved in maintaining intracellular H(2)O(2)
133                   CDC23 and BUB1B, two genes crucially involved in mitotic checkpoint progression, we
134            Long noncoding RNAs (lncRNAs) are crucially involved in multiple biological processes, but
135 permutation in the other CDRs of PGT145 were crucially involved in stabilizing the structure of the H
136                Macrophages and microglia are crucially involved in the formation and repair of demyel
137  cells (i.e.,the subretinal space), which is crucially involved in the pathobiology.
138 inity receptor for IgE, FcepsilonRI, and are crucially involved in the pathogenesis of AD by inducing
139  neuroprotective function of VEGF on RGCs is crucially involved to preserve injured RGCs such as in g
140 re We implicate Nectin1 and Nectin4 as being crucially involved, as loss of either induces a low pene
141 sized in the thyroid gland in a process that crucially involves the iodoglycoprotein thyroglobulin.
142                                              Crucially, IR-PHI images show structure that reflects th
143                                              Crucially, it is in the neighbourhood of the equilibrium
144 ed learning was at least twice as fast, and, crucially, it persisted for 6 months after the end of tr
145                                         Yet, crucially, its longer-term history and links with Europe
146 erefore, our modeling framework provides the crucially lacking evaluation indicators for airlines, po
147 UN2, P = 1.13 x 10(-15)), seven of which had crucially low minor allele frequency in European populat
148                                              Crucially, metacognitive skills enable us to adjust ongo
149                                              Crucially, model comparisons showed that within-alternat
150 onal sulfation of specific tyrosine residues crucially modulates potency.
151                                              Crucially, MORE significantly reduced opioid dose over t
152                                              Crucially, nearly every study was conducted in Europe or
153 able tissues give rise to arrhythmias, it is crucially necessary to understand the electrical dynamic
154                                New drugs are crucially needed for children with cancer.
155 ction of primary data for neonatal herpes is crucially needed to reduce uncertainty and refine future
156 specifically for brief retention periods but crucially not for longer durations.
157         Structural molecular biology depends crucially on computational techniques that compare prote
158             Cellular differentiation depends crucially on division state and time.
159 stems, land, atmosphere and oceans - depends crucially on global observations: this paper focuses on
160 nd that ligand discrimination likely depends crucially on individual contacts being ~200 nm in radius
161                    Modern computation relies crucially on modular architectures, breaking a complex a
162 lf-compressed soliton, a process that relies crucially on phase-matching.
163 ite range of functions, many of which depend crucially on the activity of molecular motors that gener
164 tion of IDP conformational ensembles depends crucially on the amount and quality of the experimental
165 gy and motility of these spirochetes depends crucially on the flagellar/cell wall stiffness ratio.
166               Mitochondrial function depends crucially on the maintenance of multiple mitochondrial D
167 netic materials consisting of dipoles depend crucially on the nature of the dipole-dipole interaction
168 y breadth development, in a way that depends crucially on the temporal pattern of immunization (or se
169                         Such analyses depend crucially on the underlying model.
170 tegy of swimming microorganisms might depend crucially on their density in order to exploit the Levy
171 nt add-on medications for severe asthma, and crucially, on selection strategies.
172                                              Crucially, oncogenic EGFR harboring both resistance muta
173 be revealed through prospective studies and, crucially, only after development of new treatment optio
174                                              Crucially, only two dimensions were relevant to prior co
175 f cytokines and cellular interactions, ILC3s crucially orchestrate lymphoid organogenesis, promote ti
176                                              Crucially, our analysis is not limited to analyzing the
177                                              Crucially, our findings highlight that spatially explici
178                                              Crucially, our findings imply that restrictive border po
179                                              Crucially, our inferences are based only on a well-estab
180                                              Crucially, our method requires only GWAS summary statist
181                                              Crucially, pairwise interactions reliably explained obse
182    Humans can easily describe, imagine, and, crucially, predict a wide variety of behaviors of liquid
183                                              Crucially, prestimulus oscillatory alpha power and phase
184                                              Crucially, protein-protein interactions between hGrx1, A
185                                              Crucially, pups accumulate certain compounds to levels t
186                                              Crucially, reduced FC of remaining hippocampal tissue co
187 chromatin structure and dynamics and thereby crucially regulate gene transcription in higher eukaryot
188                                     IL-6 may crucially regulate this process; however, the underlying
189 control of active Src and FAK levels, and so crucially regulates their cancer-associated biological o
190                     Human social interaction crucially relies on the ability to infer what other peop
191 the increasing number of nighttime jobs that crucially rely on the availability of cognitive resource
192  sequences have received scant scrutiny and, crucially, remain to be addressed.
193 he conserved NK-2 homeobox gene ceh-24 to be crucially required for flipping.
194 w that extracellular signalling pathways are crucially required for threat memory formation.
195                                              Crucially, researchers often elect to forego the cumbers
196 lly experiencing training examples and then, crucially, respond correctly (generalize) to previously
197 olecular properties of the metal complex are crucially responsible for triggering the selective assem
198                                              Crucially, risk was not derived from explicit, risk-desc
199                                              Crucially RQ is not made or used by any parasitic hosts
200                                              Crucially, sequence patterns that support an expanded co
201                                              Crucially, sister chromatid separation must be delayed u
202            There were many similarities but, crucially, some differences in biomarker levels (IL-1bet
203                                              Crucially, speech-in-noise deficits are better assessed
204                                        Water crucially stabilizes these cooperative interactions to c
205                                              Crucially, stronger activity in the midbrain/PAG during
206                                              Crucially, studies continue to assert benefits to choose
207                                              Crucially, such "triplet-sensitized CO-release" occurred
208                                              Crucially, such temporal organization relates to anti-co
209 y (TIMS) functionality of the instrument can crucially support unravelling the complex molecular comp
210          The metabolic connectivity analyses crucially supported the neuroprotective effect of biling
211                                              Crucially, task relevance modulated these spectral corre
212                                              Crucially, TEM also aligns with empirically recorded rep
213  praying mantis (Sphodromantis lineola) and, crucially, that prey with high-contrast stripes become l
214 re encoded in the ventral striatum (VS), and crucially, that SRPE VS activity is responsible for the
215 e wound pathogens in planktonic culture and, crucially, that this activity is maintained against Acin
216                                              Crucially, the changes in functional brain connectivity
217                                              Crucially, the compartmentalization enabled the formatio
218                                              Crucially, the crossed hand posture elicited enhanced ac
219  compared to those collected in solution and crucially, the crystalline samples display thermal stabi
220                                              Crucially, the delay between excitation and inhibition d
221                                              Crucially, the different objects were sequentially sampl
222                                              Crucially, the distribution of gene expression in many o
223                                              Crucially, the effect of 10 Hz flicker on task performan
224                                              Crucially, the free energy principle allows one to inter
225                                              Crucially, the gain-of-function mutations could be pharm
226 by a conjunction of pai-pai, C-H...pai, and, crucially, the hydrophobic effect.
227                                              Crucially, the increased use of ipsilateral secondary mo
228                                              Crucially, the magnitude of the DMN connectivity reducti
229                                              Crucially, the model matches the experimental results on
230                                              Crucially, the neuron's receptive field (i.e., its respo
231                                              Crucially, the observed between-study variability is acc
232                                         Most crucially, the proposed rule included two new OPO perfor
233                                              Crucially, the receptors feature high sensitivity and se
234                                              Crucially, the reduced mitochondrial Ca(2+) uptake is mi
235 he fact that both the stimulation site, and, crucially, the regime of brain network dynamics, can inf
236                                              Crucially, the relation between an action and the emotio
237                                              Crucially, the spines added after E2 rescue were no more
238                                              Crucially, the STN and lateral PFC beta decrease was sig
239                                              Crucially, the subregion showing the highest reward-rela
240                                              Crucially, the two images, one with a visual form and th
241 ts' amongst the broad pattern of decline and-crucially-the key conditions for these cases.
242                                              Crucially, these abnormalities were rescued by transgeni
243 y motor axons, between 18 and 24 months and, crucially, these changes correlate with early temperatur
244                                              Crucially, these complexes feature the requisite strong
245 he perimeter of within-person voice spaces - crucially, these distributions were missing their centre
246                                              Crucially, these effects operated at different cortical
247                                              Crucially, these electrodes show a marked improvement in
248                                              Crucially, these findings describe a mechanism by which
249 687), and nonventricular CSF (n = 939), and, crucially, these imaging markers provided greater power
250                                              Crucially, these mappings were not one-to-one.
251                                              Crucially, these results could not be explained by chang
252                                              Crucially, they also need to compete for the interpretat
253 nvestigate social dynamics across time, and, crucially, they rarely study social behavior under natur
254                                              Crucially this highlights how new drugs, introduced to c
255                                              Crucially this reduced surface expression did not cause
256                                              Crucially, this association carried opposite consequence
257                                              Crucially, this cooperative elite is more prevalent in s
258                                              Crucially, this effect is specific to upright faces, whe
259                                              Crucially, this formal (variational) treatment seeks to
260                                              Crucially, this functionality will allow users of BCI-FE
261                                              Crucially, this highlights a direct connection between l
262                                              Crucially, this individual-level support, rather than cu
263                                              Crucially, this mirrors the hierarchical organization of
264                                              Crucially, this motivated misremembering effect occurs c
265                                              Crucially, this positive linkage was strengthened when p
266                                              Crucially, this reactivity was specific to RF as it was
267                                              Crucially, this relationship holds not only in natural e
268                                              Crucially, this sensory attenuation was only apparent wh
269                                              Crucially, this trade-off is easily masked by behavioral
270  no assistance was given (experiment 1) and, crucially, this was the case even when choosing the pros
271                                              Crucially, three of these domains would be lost or disru
272  hierarchies over levels of abstraction and, crucially, time - and how this underwrites agency.
273  Instead, our data show that Arg contributes crucially to ligand sensitivity via a hydrogen bond netw
274 le structure and conformation and contribute crucially to protein-protein interactions.
275                                              Crucially, trametinib also significantly ameliorated ren
276                                              Crucially, trial-by-trial manipulation of sensory uncert
277          Failure, damage spread and recovery crucially underlie many spatially embedded networked sys
278                                   Symmetries crucially underlie the classification of topological pha
279                                              Crucially, VOTC in blind represents the categorical memb
280                                              Crucially, warmer temperatures in late winter delayed th
281                                              Crucially we found that it is possible to integrate data
282                                              Crucially we show that the children were not influenced
283                                              Crucially, we also explore the novel use of deep represe
284                                              Crucially, we also observe this phenomenon in other gene
285                                              Crucially, we also show that effort-induced functional c
286                                              Crucially, we analyze the asymmetry factors of the road
287                                              Crucially, we demonstrate that S-MGBs do not show cross-
288                                              Crucially, we demonstrate through mediation analysis tha
289                                              Crucially, we describe the real time partitioning of ove
290                                              Crucially, we discovered that a single formulation combi
291                                              Crucially, we find that both the nuclear spin and electr
292                                              Crucially, we find that each active site of a transposas
293                                              Crucially, we find that this difference between mnemonic
294                                              Crucially, we found that the medial part of PMC, putativ
295                                              Crucially, we independently varied the number of target
296                                              Crucially, we model these genes in terms of switch-like
297                                              Crucially, we recruited a sample of left-handers presele
298                                              Crucially, we show that histamine permits NMDA receptor-
299                                              Crucially, when sampling was free, participants sampled
300                                              Crucially, when the target was stimulated, this response

 
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