ライフサイエンスコーパス: cryoEM

1 cryoEM images of WEEV were used to determine the first t

2 A cryoEM reconstruction of CAV21 complexed with ICAM-1 sho

3 A cryoEM structure of the MiDAC complex reveals that this

4 s-linked heads and tails and produced an 8-A cryoEM reconstruction of the cross-linked head-tail comp

5 We have generated an 8-A cryoEM reconstruction of this state for myosin V and use

6 ing actin's D-loop region based on our 3.9 A cryoEM reconstruction suggests that oxidation by Mical r

7 Guided by a cryoEM-based model of the hexagonal lattice of HIV-1 CA,

8 Here, we present a cryoEM reconstruction of a yeast preinitiation complex a

9 Finally, we present a cryoEM structure of BrxX bound to a phage-encoded inhibi

10 Here, we present a cryoEM structure of the Aap of the archaeal model organi

11 Here, we present a cryoEM study of a tubular assembly of CA and a high-reso

12 Here, we report a cryoEM snapshot of PA(pore) translocating the N-terminal

13 esolution is not always uniform throughout a cryoEM map, and it can be useful to estimate the resolut

14 Taken together with a cryoEM structure of sAB bound human nicotinic acetylchol

15 al. show us how they are put together with a cryoEM structure of the 90S processome that initiates ri

16 with Fab C10 stabilize the viruses allowing cryoEM structural determination to ~10 angstrom resoluti

17 ical importance of the N-terminal 10 aa, and cryoEM reconstruction of the one with six residues trunc

18 itor the process with biochemical assays and cryoEM structural analysis in parallel.

19 mics simulations, X-ray crystallography, and cryoEM.

20 y between live-cell fluorescence imaging and cryoEM/ET structural analysis, as demonstrated by visual

21 , interaction mapping, mass spectrometry and cryoEM to study the role of ZNHIT2 in the regulation of

22 Negative stain and cryoEM data of several examples of BRIL-membrane protein

23 wild-type B19 with the crystal structure and cryoEM reconstruction of recombinant B19 particles consi

24 lations, analytical ultracentrifugation, and cryoEM to structurally characterize the solution state o

25 Here, we determine a 2.2 angstrom cryoEM structure of qNOR from Alcaligenes xylosoxidans,

26 Here, we determine a 3.7 angstrom cryoEM structure of PfATP4 purified from CRISPR-engineer

27 odeling Y30, F32 and I34 of C11 in available cryoEM pol III structures predicts a hydrophobic patch t

28 Both cryoEM and EPR suggest that, within the oligomer, the di

29 rmination of the structure of the complex by cryoEM revealed the "orphan" two-component response regu

30 determining the structure of this complex by cryoEM.

31 ccess in ribosome structure determination by cryoEM has opened the door to defining structural differ

32 he structure of E.coli RecBCD, determined by cryoEM at 3.8 A resolution, with a DNA substrate that re

33 (LDL.LDLr) at extracellular pH determined by cryoEM.

34 Here, by cryoEM and sub-particle reconstruction, we have determin

35 Here, by cryoEM of KSHV at 6-A resolution, we show that SCP forms

36 secondary structural elements identified by cryoEM locates 15 amphipathic alpha-helical regions on t

37 Direct observation by cryoEM reveals that this occupancy-enhancing N-terminal

38 with dimensions similar to those observed by cryoEM; on the other hand, the hydrophobic effect shrink

39 sociated tegument complex (CATC) obtained by cryoEM and sub-particle reconstruction.

40 Images obtained by cryoEM showed that the extracellular stick-like domain o

41 lence factor of Streptococcus pneumoniae, by cryoEM.

42 rticle is determined to 10.4 A resolution by cryoEM image reconstruction.

43 Here we show by cryoEM that the recombinant sNS1 exists in multiple olig

44 form of PFK1 (PFKL) in the R- and T-state by cryoEM, providing insight into eukaryotic PFK1 allosteri

45 ures in inward- and outward-facing states by cryoEM.

46 of rice dwarf virus that has been studied by cryoEM at 6.8A.

47 ese mechanistic principles were validated by cryoEM analysis of an expanded variant of Hsp16.5 in com

48 provided into how secretion systems work by cryoEM, with a focus on type III secretion systems.

49 V MCP capsomers were subtracted from the CIV cryoEM reconstruction, showed that there are at least th

50 Here we combine cryoEM and cryoET to determine high-resolution in situ s

51 This combined cryoEM-Nanogold labeling study has provided the first lo

52 Here, we compare cryoEM structures of a mammalian K(ATP) channel bound to

53 ilities and limitations of two complementary cryoEM techniques for studying bacterial secretion syste

54 Here, by direct electron-counting cryoEM, we have determined the structures of the Leishma

55 ticle determined by electron cryomicroscopy (cryoEM) and single-particle analysis at about 4.3 A reso

56 ing mechanism using electron cryomicroscopy (cryoEM) and small-angle X-ray scattering.

57 , was determined by electron cryomicroscopy (cryoEM) and three-dimensional reconstruction at 23-A res

58 xes.Single-particle electron cryomicroscopy (cryoEM) can circumvent some of the problems of x-ray cry

59 rify a specimen for electron cryomicroscopy (cryoEM) faster than proteins diffuse to the air-water in

60 ementing this work, electron cryomicroscopy (cryoEM) has provided relatively low-resolution structure

61 graphy (cryoET), an electron cryomicroscopy (cryoEM) modality, has changed our understanding of biolo

62 econstructions from electron cryomicroscopy (cryoEM) of bovine papillomavirus at 9 A resolution with

63 w-resolution (20 A) electron cryomicroscopy (cryoEM) structures of this gp140 trimer, which adopts tw

64 plex, determined by electron cryomicroscopy (cryoEM) to a resolution of 2.5 A.

65 have determined by electron cryomicroscopy (cryoEM), at about 11 A resolution, the structure of a cl

66 by single-particle electron cryomicroscopy (cryoEM).

67 ne papillomavirus by electron cryomicrosopy (cryoEM), at approximately 3.6 A resolution.

68 majority of the vertex model in well-defined cryoEM density.

69 Denoising cryoEM images can not only improve downstream analysis b

70 Building upon the recently described cryoEM structure of Kv7.2 complexed with retigabine and

71 using minimal shell components and determine cryoEM structures of these to decipher the principle of

72 Here, we determine cryoEM maps of full-length human SERINC3 and an ICL4 del

73 tivation in light of the recently determined cryoEM structure of a complete TCR-CD3 complex.

74 s not induce oligomer heterogeneity enabling cryoEM analysis of the complexes.

75 tein assemblies at 20 A, and an experimental cryoEM map at 23.5 A resolution.

76 otide-bound and -free states, and the fitted cryoEM structure of the D2 hexamer ring, which provide a

77 Here we report five cryoEM structures of the human ORC (HsORC) that illustra

78 site for structure-based drug design and for cryoEM to become widely interesting to pharmaceutical in

79 ze of conventional Fab-protein complexes for cryoEM.

80 esent a multifunctional specimen support for cryoEM, comprising large-crystal monolayer graphene susp

81 econstructions of comparable resolution from cryoEM images of asymmetric particles.

82 rmining regions, and discover sequences from cryoEM density maps of serum-derived polyclonal antibodi

83 the particle properties leading to improved cryoEM outcomes, especially for challenging membrane pro

84 In recent years, advances in cryoEM have dramatically increased the resolution of rec

85 n its small 2.5 nm size and detectability in cryoEM.

86 sids conjugated to Au102_C6MI were imaged in cryoEM for single particle reconstruction to localize Au

87 identifying regions or domains or motifs in cryoEM maps of large macromolecular assemblies (such as

88 Low signal-to-noise ratio (SNR) in cryoEM images reduces the confidence and throughput of s

89 ld, and the bound Nanogold was visualized in cryoEM images of the reduced, gold-labeled receptor.

90 developed to identify proteins in ab initio cryoEM maps.

91 epresentations of local regions in the input cryoEM maps.

92 inding capabilities and fitting the CTD into cryoEM density of the phi29 motor shows that the CTD dir

93 ere we present four in situ and one isolated cryoEM structures of the trimeric spike of the cytoplasm

94 duced disaggregation and have determined its cryoEM structure.

95 d to be intrinsically disordered, and little cryoEM density is observed for them.

96 s on the capsid by cryoelectron microscopic (cryoEM) analysis, and testing their effects on viral inf

97 Electron cryo-microscopy (cryoEM) and image analysis showed that, compared with th

98 Electron cryo-microscopy (cryoEM) and X-ray solution scattering were used to show

99 combined modes of electron cryo-microscopy (cryoEM), we have solved the structure of the Pyrococcus

100 Cryoelectron microscopy (cryoEM) and single-particle image reconstruction methods

101 olution by means of cryoelectron microscopy (cryoEM) and three-dimensional image reconstruction.

102 t-of-its-kind BSL-3 cryoelectron microscopy (cryoEM) containment facility.

103 eling methods using cryoelectron microscopy (cryoEM) density maps as constraints are promising approa

104 The cryoelectron microscopy (cryoEM) image reconstruction of CAV21 is consistent with

105 been determined by cryoelectron microscopy (cryoEM) image reconstruction to a resolution of approxim

106 esolution of 6 A by cryoelectron microscopy (cryoEM) single-particle image reconstruction.

107 Here, we report cryoelectron microscopy (cryoEM) structural analysis of two gammadelta TCRs, G115

108 were determined by cryoelectron microscopy (cryoEM) to 7.5-A and 11.3-A resolution, respectively, as

109 Here, we use cryoelectron microscopy (cryoEM) to determine that Escherichia coli ExoVII compri

110 le fluorescence and cryoelectron microscopy (cryoEM) to show that CENP-A incorporation establishes a

111 this paper, we used cryoelectron microscopy (cryoEM) to visualize destabilized mutants of T4 lysozyme

112 onance (SSNMR), and cryoelectron microscopy (cryoEM), have enabled high-resolution insights into thei

113 electrophoresis and cryoelectron microscopy (cryoEM), the ability of the reconstituted LDL receptor t

114 of single particle cryoelectron microscopy (cryoEM), x-ray crystallography has remained the preferre

115 s, and imaged using cryoelectron microscopy (cryoEM).

116 Additionally, cryo-electron microscopy (cryoEM) analysis of third-side insertion mutants showed

117 electron-counting cryo-electron microscopy (cryoEM) and asymmetric reconstruction.

118 4 angstrom by cryogenic electron microscopy (cryoEM) and built an atomic model for the entire Tv-DMT.

119 stion by combining cryo electron microscopy (cryoEM) and cross-linking mass spectrometry (XL-MS) to s

120 Advances in cryo-electron microscopy (cryoEM) and deep-learning guided protein structure predi

121 rus type 1 by cryogenic electron microscopy (cryoEM) and exhaustively classified them to characterize

122 ed single particle cryo-electron microscopy (cryoEM) and led to a wave of near-atomic resolution (typ

123 Using cryo-electron microscopy (cryoEM) and single particle cryo-electron tomography (SP

124 ugh co-analysis by cryo-electron microscopy (cryoEM) and solid-state nuclear magnetic resonance (SSNM

125 , as determined by cryo-electron microscopy (cryoEM) and subparticle reconstruction.

126 Cryo-electron microscopy (cryoEM) data of full-length BTK, on the other hand, prov

127 g and fitting into cryo-electron microscopy (cryoEM) density maps.

128 Cryo electron microscopy (cryoEM) has emerged as an excellent tool for resolving h

129 itectures by using cryo-electron microscopy (cryoEM) image reconstruction techniques.

130 was determined by cryo-electron microscopy (cryoEM) image reconstruction.

131 bS antagonist; its cryo-electron microscopy (cryoEM) image suggests that the N-terminal domains of th

132 is (PAGE) and cryogenic electron microscopy (cryoEM) imaging.

133 ss that has turned cryo-electron microscopy (cryoEM) into an exceptional SBDD tool, and the wealth of

134 Cryo-electron microscopy (cryoEM) is becoming the preferred method for resolving p

135 5.3 A resolution, cryo-electron microscopy (cryoEM) map of Chikungunya virus-like particles (VLPs) h

136 -atomic-resolution cryo electron microscopy (cryoEM) maps are reconstructed ab initio from unidentifi

137 se components into cryo electron microscopy (cryoEM) maps of their assemblies.

138 uited for the cryogenic electron microscopy (cryoEM) method microcrystal electron diffraction (MicroE

139 in single-particle cryo electron microscopy (cryoEM) now enable structure determination at atomic res

140 resolution by cryogenic electron microscopy (cryoEM) of cellular extracts.

141 were determined by cryo-electron microscopy (cryoEM) reconstruction to resolutions varying from 8.5 t

142 11 single-particle cryo-electron microscopy (cryoEM) reconstructions of the complex of bacterial 30S

143 ngle-particle cryogenic electron microscopy (cryoEM) remains a bottleneck for routinely obtaining hig

144 Cryogenic electron microscopy (cryoEM) resolved the aptamer-S protein complex in the op

145 nometer resolution cryo-electron microscopy (cryoEM) structural analysis of an adenoviral vector, Ad3

146 ongatus KaiB and a cryo-electron microscopy (cryoEM) structure of a KaiBC complex.

147 three-dimensional cryo-electron microscopy (cryoEM) structure of an infectious ZIKV (strain H/PF/201

148 Here we report a cryo-electron microscopy (cryoEM) structure of PDE6 complexed to GTP-bound Galpha(

149 ere we present the cryo-electron microscopy (cryoEM) structure of the hnRNPA2 LCD fibril core and dem

150 ella, based on the cryo electron microscopy (cryoEM) structure of the Methanospirillum hungatei archa

151 nometer resolution cryo-electron microscopy (cryoEM) structures of HD5 complexed with both neutraliza

152 ur high-resolution cryo-electron microscopy (cryoEM) studies of B41 in complex with a B41-specific an

153 Here, we use cryo-electron microscopy (cryoEM) to decipher the mechanism of action of a potent

154 e, consistent with cryo-electron microscopy (cryoEM) tomography, within which the boundaries of signa

155 Single-particle cryo electron microscopy (cryoEM) typically produces density maps of macromolecula

156 ng single-particle cryo-electron microscopy (cryoEM) under catalytic turnover conditions with site-di

157 Cryogenic electron microscopy (cryoEM) uses images of frozen hydrated biological specim

158 ngle-particle cryogenic electron microscopy (cryoEM), revealing subtype-specific interactions and RNA

159 ion or cryogenic-sample electron microscopy (cryoEM), scientists verify whether small-molecule ligand

160 this T6SS and, by cryo electron microscopy (cryoEM), show the structure of its post-contraction shea

161 lies based on cryogenic electron microscopy (cryoEM), the dimerization interface is substantially dis

162 em (T2SS) by using cryo-electron microscopy (cryoEM), these pili showed indistinguishable helical par

163 Here, using cryo-electron microscopy (cryoEM), we analyzed the size distribution and morpholog

164 Here, based on cryo-electron microscopy (cryoEM), we report a 7-A resolution structure of the inf

165 ion signal in cryogenic electron microscopy (cryoEM).

166 ngle-particle cryogenic electron microscopy (cryoEM).

167 As an example, we apply these methods to new cryoEM maps of the mature bacteriophage P22, reconstruct

168 organizations corresponding to the observed cryoEM density map.

169 Classification of cryoEM images reveals starfish-like rings with skewed pe

170 cines.The result shows that a combination of cryoEM and molecular modeling can yield details of the a

171 Furthermore, the combination of cryoEM with the rapidly emerging use of in situ cryo ele

172 plicable to the rapidly increasing number of cryoEM density maps of macromolecular assemblies.

173 op' resource for deposition and retrieval of cryoEM maps, models and associated metadata.

174 r reliably and rapidly increasing the SNR of cryoEM images and cryoET tomograms.

175 DRPnet excels on cryoEM datasets that have low contrast or clumped partic

176 d mapping conserved suppressor residues onto cryoEM structural models of assembling human spliceosome

177 ne or another pair of subunits in crystal or cryoEM structures of RecBCD bound to DNA.

178 nted where SID agrees with solved crystal or cryoEM structures or provides connectivity maps that are

179 In addition, our cryoEM structure of a Swc5-nucleosome complex suggests t

180 By contrast, our cryoEM structures of H2AK119ub nucleosomes show ubiquiti

181 Based on our cryoEM structure, we design a series of mutants to rever

182 Here, we establish through single particle cryoEM and chemical analysis of two forms of the Azotoba

183 manuscript demonstrate that single particle cryoEM is capable of competing with X-ray crystallograph

184 ombine biochemical analysis, single particle cryoEM, and DEER spectroscopy in lipid bilayers along wi

185 ful as a fiducial marker for single-particle cryoEM analysis of HCV E2.

186 ve examined the potential of single-particle cryoEM for determining the structure of influenza-virus

187 Here, we present single-particle cryoEM structures that show how a 33-mer polypeptide unr

188 Here, using single-particle cryoEM, we have determined the structure of the mature H

189 mined at 2.8 A resolution by single-particle cryoEM.

190 Here, we report sub-particle cryoEM reconstructions of HCMV virions at 2.9 A resoluti

191 We performed cryoEM-guided molecular dynamics flexible fitting simula

192 ng the C-terminal half of SCP and performing cryoEM reconstruction, we demonstrate that SCP's N-termi

193 Here, we present cryoEM structures of ClpXP-substrate complexes that reve

194 Here we present cryoEM structures of two Hsp104 variants in both crossli

195 fibrils is markedly different from previous cryoEM models of Abeta(1-40) fibrils.

196 However, the vast majority of published cryoEM methodologies focus on the characterization of ae

197 Recent cryoEM density maps of Abeta(42) fibrils obtained at low

198 A recent cryoEM structure of yeast CMG shows that duplex DNA ente

199 Comparison with a recent cryoEM structure reveals conformational differences in t

200 hannel activity, mutagenesis, and the recent cryoEM structure for hERG were employed.

201 Here, we report cryoEM structural analyses of ex vivo and in vitro assem

202 Here, we report cryoEM structures of an H2BK120ub nucleosome showing tha

203 Here, we report cryoEM structures of human CLC-2 at 2.46 - 2.76 angstrom

204 We report cryoEM structures of the SAM complex from Myceliophthora

205 Here, we report cryoEM structures of two distinct full-length alpha/beta

206 ally, were modelled into the 28 A resolution cryoEM map of the procapsid.

207 acid sequences, the 2.7 angstrom resolution cryoEM map showed Nora virus to have T = 1 symmetry with

208 Using near-atomic resolution cryoEM reconstruction and single filament TIRF microscop

209 (2020a) present near-atomic resolution cryoEM structures of a proton-pumping vacuolar ATPase fr

210 Here, we report the near-atomic resolution cryoEM structures of the Escherichia coli AcrAB-TolC mul

211 apsid proteins in our near-atomic-resolution cryoEM map of the grass carp reovirus virion, a member o

212 he ongoing interpretation of high resolution cryoEM and x-ray electron density maps.

213 g from, that inferred from a high resolution cryoEM structure of a triskelion in a clathrin basket.

214 Here we present four high resolution cryoEM structures of the nitrogenase MoFe-protein, sampl

215 c models based on medium- to high-resolution cryoEM density maps.

216 th human SLFN14 and report a high-resolution cryoEM reconstruction of the SLFN14*RNA complex.

217 These high-resolution cryoEM structures have clarified important domains not p

218 Here, we present five high-resolution cryoEM structures of CVB representing different stages o

219 High-resolution cryoEM structures of the intron in different liganded st

220 lographic structures) with medium-resolution cryoEM densities.

221 techniques with the subnanometer-resolution cryoEM structure of rotavirus, we now provide a more det

222 s capsid-binding properties using NMR, SAXS, cryoEM and SPR.

223 et's first CNN pretrained with only a single cryoEM dataset can be used to detect particles from diff

224 in the act of OMP delivery to BAM, and solve cryoEM structures of a series of complexes.

225 MOTIF-EM takes cryoEM volumetric maps as inputs.

226 The cryoEM density map also reveals few, weak interactions b

227 The cryoEM image reconstruction permits a nearly complete tr

228 The cryoEM structure of FcRY at pH 6 revealed a compact doub

229 The cryoEM structure of the FcRY-IgY revealed symmetric bind

230 The cryoEM structure, sequence comparison, and protein fold

231 of isolated C-linker/CNBD fragments and the cryoEM structures of related CNG, HCN, and KCNH channels

232 gh-resolution structure determination by the cryoEM method MicroED and potentially by serial femtosec

233 the resulting capsid, which was shown by the cryoEM study to closely resemble the infectious mature v

234 fluorescence measurements, we determine the cryoEM structure of the naturally long-lived ribosome co

235 om native V. cholerae cells to determine the cryoEM structure of the VcPilQ secretin in amphipol to ~

236 We determined the cryoEM structure of CypA in complex with the assembled H

237 antibody to block fusion, we determined the cryoEM structures of the C10-ZIKV complex at pH levels m

238 The structural features revealed from the cryoEM map lead to a juxtaposed stacking model of choles

239 y subtracting a pseudoatomic capsid from the cryoEM reconstruction.

240 rientation between helix 9 segments from the cryoEM study, the solid state NMR data lead to a unique

241 Furthermore, the cryoEM structure of the variant shows that the presence

242 alysis of the conformational ensemble in the cryoEM data highlights the dynamic nature of the contact

243 cated localizes the N terminus of SCP in the cryoEM density map and enables us to construct a pseudoa

244 NMR models for Abeta(17-42) fit well in the cryoEM density map and reveal that the juxtaposed protof

245 nterface at the local three-fold axis in the cryoEM map and confirmed its functional importance by mu

246 trimeric surface protrusions observed in the cryoEM map.

247 ntacts made between GluA2 TMD and Stg in the cryoEM structures.

248 ing of the Fab and virus structures into the cryoEM densities identified the footprints of each antib

249 and penton base crystal structures into the cryoEM density established that alpha-helices of 10 or m

250 This model was fitted into the cryoEM density for each of the 25 trimeric CIV capsomers

251 er, the resulting model fits better into the cryoEM density map than the initial template structure.

252 h viruses and of ICAM-1 were fitted into the cryoEM density maps.

253 l domains D1 and D2 has been fitted into the cryoEM density of the complex.

254 3)Sigma3(3) heterohexameric complex into the cryoEM image of an intact virion, reveal molecular event

255 The overall fit of the L1 model into the cryoEM map is excellent, but residues 402-446 in the 'C-

256 logy model for the MCP upper domain into the cryoEM map reveals that SCP binds MCP largely via hydrop

257 Analysis of the cryoEM density was enhanced by docking the crystal struc

258 learn models capturing the complexity of the cryoEM image formation process.

259 Comparison of the cryoEM pore complex to the prepore structure obtained by

260 , giving us an independent validation of the cryoEM results.The two structures also augment our under

261 Comparison of the cryoEM structure with bent and extended models for the i

262 Based on the cryoEM measurements and on NMR data, we probe amyloid fi

263 for medaka and human is modeled based on the cryoEM structure of Tetrahymena telomerase, providing in

264 Here, we present the cryoEM structure of a displacement loop of human RAD51 t

265 Here, we present the cryoEM structure of EndoS in complex with the IgG1 Fc fr

266 Here, we present the cryoEM structure of the known CI assembly intermediate C

267 Here, we present the cryoEM structure of the oncogenic protein kinase client

268 Here we report the cryoEM structure at 3.3 angstrom of human CMG bound to f

269 Here we report the cryoEM structure of a coronavirus S glycoprotein in the

270 Here, we report the cryoEM structure of a K(ATP) channel harboring the neona

271 Here we report the cryoEM structure of a Ric1-Rgp1-Rab6 complex representin

272 Here we report the cryoEM structure of a super-constricted two-start dynami

273 We further report the cryoEM structure of human CMG bound to the replisome hub

274 Here we report the cryoEM structure of PZM21 bound muOR in complex with G(i

275 Here, we report the cryoEM structure of the RapZ:GlmZ complex, revealing a c

276 Here, we report the cryoEM structure of yeast U1 snRNP at 3.6 A resolution w

277 Here, we report the cryoEM structures of metabotropic glutamate receptor 5 (

278 ts co-localize with Pol V, and we report the cryoEM structures of two complexes associated with Pol V

279 Here we solve the cryoEM structure of the IL-11 receptor recognition compl

280 Consistent with this, the cryoEM structure of MiDAC reveals a unique and distincti

281 opaz-Denoise will be of broad utility to the cryoEM community for improving micrograph and tomogram i

282 ded into domains to obtain a good fit to the cryoEM density.

283 tomated fLM grid atlas that is linked to the cryoEM grid atlas, followed by cryofLM imaging after fre

284 Using the cryoEM method MicroED, we discover that one segment, 19-

285 Using the cryoEM method microelectron diffraction, we determined t

286 argeted areas are automatically converted to cryoEM/ET and refined using fluorescent fiducial beads.

287 Tomographic cryoEM images of the cell division site show separate co

288 rom cryo-electron microscopy and tomography (cryoEM/ET).

289 Cryoelectron microscope tomography (cryoEM) and a fluorescence loss in photobleaching (FLIP)

290 Here we use cryoEM to determine the structures of fibrils formed fro

291 Here we use cryoEM to study ATP binding in the homo-oligomeric archa

292 Here, we have used cryoEM to determine structures of GroEL, GroEL-ADP.BeF(3

293 Here we used cryoEM to determine the structure of the intact LliK CNG

294 re to approximately 10-A resolution by using cryoEM and the iterative real-space reconstruction metho

295 Here, we overcome these challenges by using cryoEM to visualize pMMO and AMO directly in their nativ

296 the structure of the C16 - Ku complex using cryoEM.

297 Here, using cryoEM we explore the structure of active PC tetramers f

298 ting analysis should prove critical in using cryoEM to solve protein-ligand complexes.

299 ing local structures of protein models using cryoEM maps as a constraint.

300 he reduced LDL receptor was visualized using cryoEM; reduced LDL receptors showed images with a diffu