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1 ative ease of expression, and amenability to crystallographic analysis.
2 51 enzyme, an observation confirmed by X-ray crystallographic analysis.
3 als of the above proteins suitable for X-ray crystallographic analysis.
4 nd 2D NMR experiments and confirmed by X-ray crystallographic analysis.
5 tion of natural proteins to facilitate X-ray crystallographic analysis.
6 pts an octahedral geometry as shown by X-ray crystallographic analysis.
7 leic acid structure, we undertook a detailed crystallographic analysis.
8 or nuclear magnetic resonance (NMR) or X-ray crystallographic analysis.
9 solute configurations were assigned by X-ray crystallographic analysis.
10 ture of one complex was established by X-ray crystallographic analysis.
11 ranging from 58 nM to 0.8 pM was chosen for crystallographic analysis.
12 e of 7k with p38alpha was confirmed by X-ray crystallographic analysis.
13 The structure of 1 was determined by X-ray crystallographic analysis.
14 to trap acyl-enzyme intermediates for X-ray crystallographic analysis.
15 N,N-dimethylamino biphenyl ligands by X-ray crystallographic analysis.
16 nctions was unambiguously confirmed by X-ray crystallographic analysis.
17 MR and IR spectroscopy, base hydrolysis, and crystallographic analysis.
18 netic and equilibrium binding parameters and crystallographic analysis.
19 istry was unequivocally established by X-ray crystallographic analysis.
20 nterface and confirmed the design with X-ray crystallographic analysis.
21 ss an (aS)-configurated biaryl axis by X-ray crystallographic analysis.
22 is mutant, evidence for which is provided by crystallographic analysis.
23 diastereomer occurred as confirmed by X-ray crystallographic analysis.
24 of miliusate was further confirmed by X-ray crystallographic analysis.
25 lidate the dimer interface proposed by prior crystallographic analysis.
26 es that was unambiguously confirmed by X-ray crystallographic analysis.
27 itions for flash-freezing crystals for X-ray crystallographic analysis.
28 multidomain proteins that are not suited to crystallographic analysis.
29 s been investigated by biochemical and X-ray crystallographic analysis.
30 e efforts, a MutS.ATP.DNA complex has eluded crystallographic analysis.
31 forms a GTP-bound complex stable enough for crystallographic analysis.
32 -azotriazapentalene, which was confirmed via crystallographic analysis.
33 tional significance that extend recent x-ray crystallographic analysis.
34 olution experiments, overcoming the need for crystallographic analysis.
35 ture of the product was elucidated via X-ray crystallographic analysis.
36 -Michael product (30) was confirmed by X-ray crystallographic analysis.
37 rocess was unambiguously determined by X-ray crystallographic analysis.
38 ic transformation and characterized by X-ray crystallographic analysis.
39 or working as NAD isostere as ascertained by crystallographic analysis.
40 tative products have been confirmed by X-ray crystallographic analysis.
41 errin A was unambiguously confirmed by X-ray crystallographic analysis.
44 le quinone anion radicals suitable for X-ray crystallographic analysis allows for the first time thei
47 tive demethylation reaction was captured via crystallographic analysis and analyzed via single-crysta
48 a bowl-shaped geometry, as revealed by X-ray crystallographic analysis and density functional theory
49 se complexes could be characterized by X-ray crystallographic analysis and employed as catalysts for
53 ge this gap uniquely enabling both nanoscale crystallographic analysis and the low-dose formation of
54 Early leads were discovered through X-ray crystallographic analysis, and a systematic survey of co
57 rized previously both structurally, by x-ray crystallographic analysis, and energetically, by scannin
58 thiones is unambiguously determined by X-ray crystallographic analysis, and this is used to correct e
59 were confirmed through single-crystal X-ray crystallographic analysis, arise from sequential inter/i
60 ient absorption spectroscopy (TA), and X-ray crystallographic analysis, assisted by unrestricted symm
61 erfering device (SQUID), FT Raman, and X-ray crystallographic analysis, assisted by unrestricted symm
63 e sites of these enzymes are the same within crystallographic analysis, but residues in the second-sp
77 re comprehensively characterized by means of crystallographic analysis, determination of pK(a) values
79 inst single-chain Fv antibodies obtained via crystallographic analysis/engineering and against commer
80 tivities, confirmed where necessary by X-ray crystallographic analysis, establish the capability of s
81 insights provide simple and accurate optical crystallographic analysis for liquid-dispersed nanomater
82 onal (2D) NMR methods and confirmed by X-ray crystallographic analysis has an unusual 3H-benzo[d]pyrr
84 on the tertiary assembly of these proteins; crystallographic analysis has revealed that the two cyto
87 he use of kinetic isotope effects (KIEs) and crystallographic analysis, in conjunction with structure
93 lative configuration was determined by X-ray crystallographic analysis), no particular difference was
95 ecules within the O(2) channel, we performed crystallographic analysis of 19 Xe laden crystals freeze
105 ation assays, surface plasmon resonance, and crystallographic analysis of a 1.5 angstrom structure de
110 eta-fold that was not observed in an earlier crystallographic analysis of a less stable version of th
113 with affinity similar to that of gp120, and crystallographic analysis of a scaffold bound to b12 rev
115 DD-transpeptidase active site--discovered by crystallographic analysis of a soluble construct of PBP2
122 steric inhibitors, a finding rationalized by crystallographic analysis of allosterically inhibited L-
124 d catalytic activity was elucidated by X-ray crystallographic analysis of an isolated Au(iii)-activat
126 this specificity with biochemical and X-ray crystallographic analysis of APPBP1-UBA3-NEDD8 complexes
130 Spectroscopic analysis in solution and X-ray crystallographic analysis of cocrystals of pyrene and NA
137 As this segment was not resolved in previous crystallographic analysis of E1 and LTag hexameric helic
148 nimized insulin receptors (IRs) have enabled crystallographic analysis of insulin-bound "micro-recept
150 the native sodium and potassium forms, and a crystallographic analysis of it complexed with an O. nov
152 uorenyl group in 19b was determined by X-ray crystallographic analysis of its N-oxide derivative (23b
158 ency to form fibrils were coupled with X-ray crystallographic analysis of nine TTR.ligand complexes.
163 lysozyme, and has been employed for routine crystallographic analysis of organic and inorganic mater
168 utilized molecular modeling based upon X-ray crystallographic analysis of renin's active site to desi
169 rminants were established based on the X-ray crystallographic analysis of representative compounds bo
172 NMR experiments, DFT calculations and X-ray crystallographic analysis of Sc(3)N@C(78) derivative 1a.
177 pplication of LCP techniques to enable X-ray crystallographic analysis of single-pass TM interactions
181 critical differences are highlighted in the crystallographic analysis of the A. oryzae structure: (i
184 We have addressed these questions through crystallographic analysis of the Atm1/ABCB7/HMT1/ABCB6 o
185 rectly correlate binding interactions with a crystallographic analysis of the binding mechanism.
187 pecificity is achieved, we carried out x-ray crystallographic analysis of the capsid protein domain b
191 hesized and the structures assigned by X-ray crystallographic analysis of the corresponding Boc-prote
192 pared and its structure established by X-ray crystallographic analysis of the corresponding Cbz-prote
197 YA/J6 (IgG3, kappa) has been investigated by crystallographic analysis of the Fab domain and its two
198 xylappaconitine from condelphine, with X-ray crystallographic analysis of the former clarifying the N
210 form and the structure established by X-ray crystallographic analysis of the methyl ester hydrochlor
216 t recent advances in the field have been the crystallographic analysis of the oxidase and the use of
226 ne of these geometries agrees with the X-ray crystallographic analysis of the thermodynamic conformat
227 ple interactions are integrated, we combined crystallographic analysis of the third and fourth PE pai
228 annot phosphorylate PtdIns(4,5)P2 Therefore, crystallographic analysis of the yeast and plant enzymes
234 iew will highlight what we have learned from crystallographic analysis of this important protein fami
239 tein purification, and high-resolution x-ray crystallographic analysis of tyvelose epimerase from Sal
243 Because eukaryotic BATs are recalcitrant to crystallographic analysis, our understanding of the mech
246 ght (MALDI-TOF) mass spectrometry, and X-ray crystallographic analysis reveal a bimetallic structure
247 with multi-angle laser light scattering and crystallographic analysis reveal that a DNA-binding frag
252 tic investigation based on spectroscopic and crystallographic analysis revealed that a putative reduc
268 d, proton, and carbon NMR spectra, and X-ray crystallographic analysis reveals the nitroso groups pos
272 hylococcus aureus, and biochemical and X-ray crystallographic analysis showed that SpFakB1 selectivel
283 ogy-dependent polymorphism using an in-depth crystallographic analysis that correlates high-resolutio
284 Here, we demonstrate using spectroscopic and crystallographic analysis that human PARP-1 has a third
285 primary adduct and established through X-ray crystallographic analysis that the adduct is the product
288 the designed protein was confirmed by X-ray crystallographic analysis: The remodeled loop adopts a c
289 and purification, and high resolution x-ray crystallographic analysis to 1.44 A of wild-type DesIV c
290 used multiple solution state techniques and crystallographic analysis to investigate the importance
295 of 1 was established by single-crystal X-ray crystallographic analysis using Cu Kalpha radiation.
297 talline photochromism phenomena of 10, X-ray crystallographic analysis was performed, revealing a sig
299 ctural assignments for 2 and 3 through X-ray crystallographic analysis, which revealed an interesting
300 photolabeling experiments, as well as X-ray crystallographic analysis with a protein prenyltransfera