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1 : fused (a protein-serine/threonine kinase), cubitus interruptus (a transcription factor), and costal
2 form of the zinc-finger transcription factor Cubitus interruptus (Ci(155)), the main effector of Hh s
4 he kinase Fused and the transcription factor Cubitus interruptus (CI) act positively upon targets.
5 hile the F box protein Slimb is required for Cubitus interruptus (Ci) and Armadillo/beta-catenin (Arm
6 e formation of a truncated repressor form of Cubitus interruptus (Ci) and by stimulating the nuclear
7 ugh phosphorylating the transcription factor Cubitus interruptus (Ci) and G protein coupled receptor
9 f Hh are the zinc-finger containing proteins Cubitus interruptus (Ci) and Gli, in flies and vertebrat
10 -regulated transcription factors, Drosophila Cubitus interruptus (Ci) and mammalian Gli proteins.
11 e formation of a truncated repressor form of Cubitus interruptus (Ci) and stimulating the transcripti
12 ctivation of vn is mediated through the gene cubitus interruptus (ci) and that this activation requir
13 hh in the germarium, while patched (ptc) and cubitus interruptus (ci) are expressed in somatic cells
15 tes the function of the transcription factor Cubitus interruptus (Ci) at three levels: protein stabil
16 oreover, we find that activated Fu regulates Cubitus interruptus (Ci) by both promoting its transcrip
17 ers the activity of the transcription factor Cubitus interruptus (Ci) by inhibiting the proteolysis o
22 lated processing of the transcription factor cubitus interruptus (Ci) in Drosophila depends on phosph
23 ate the activity of the transcription factor Cubitus interruptus (Ci) in response to the Hh signal.
26 phorylation by PKA, GSK3, and CKI to prevent Cubitus interruptus (Ci) processing through unknown mech
28 e known Hh cytoplasmic components, including Cubitus interruptus (Ci) the only known target of Hh sig
29 n Hh signaling by regulating the activity of Cubitus interruptus (Ci) through phosphorylation of the
30 The Hedgehog (Hh) signal is transduced via Cubitus interruptus (Ci) to specify cell fates in the Dr
31 expression, accomplished through binding of Cubitus interruptus (Ci) to the Cyclin E promoter, media
34 , a protein secreted by posterior cells, and Cubitus interruptus (Ci), a protein in the Hh response p
35 In Drosophila, Hh transduces its signal via Cubitus interruptus (Ci), a transcription factor present
36 the secreted protein, Hedgehog (Hh), and by Cubitus interruptus (Ci), a transcriptional effector of
37 ns of Hh have been shown to be transduced by Cubitus interruptus (Ci), a zinc finger transcription fa
38 l for activation by the transcription factor Cubitus interruptus (Ci), and a cluster of binding sites
39 tial proteolysis of the transcription factor Cubitus interruptus (Ci), and the ability of a complex c
40 his complex, Costal2 (Cos2), Fused (Fu), and Cubitus interruptus (Ci), bind each other directly to fo
43 ssion of the Hh pathway transcription factor cubitus interruptus (ci), leading to lower levels of ptc
44 BP, interacts with the transcription factors Cubitus interruptus (CI), MAD, and Dorsal (DL) and funct
45 els and rate of nuclear entry of full-length Cubitus interruptus (Ci), the Hh signaling target, are e
47 ence of Hh, the sole Drosophila Gli homolog, Cubitus interruptus (Ci), undergoes partial proteolysis
48 creased stability of a transcription factor, Cubitus interruptus (Ci), whereas Wg signal transduction
49 a vertebrate homolog of the Drosophila gene cubitus interruptus (ci), which encodes a transcriptiona
52 ion of the zinc finger transcription factor, Cubitus interruptus (Ci), while other studies suggest a
69 of the Hedgehog pathway transcription factor cubitus interruptus (Ci)/Gli by Cul3-Hedghog-induced MAT
71 onversion of the latent transcription factor Cubitus interruptus (Ci)/Gli into its activator form (Ci
72 edgehog (Hh) signaling pathway by inhibiting Cubitus interruptus (Ci)/Glioma-associated oncogene homo
73 by preventing proteolysis of the full-length Cubitus interruptus (Ci-155) transcriptional activator t
75 in ligase that is likely to act by targeting Cubitus interruptus and an unknown activator of hedgehog
76 conserved zinc finger domain with Drosophila Cubitus interruptus and are believed to function as tran
79 a repressor form of the transcription factor Cubitus interruptus can block decapentaplegic misexpress
80 s the Hedgehog signal transduction component Cubitus interruptus for degradation by Cullin-3 and the
82 discs causes the accumulation of full-length Cubitus interruptus protein, but not of Smoothened, in b
83 ehog, patched, decapentaplegic, wingless and cubitus interruptus) are expressed in analogous patterns
85 ation of Hedgehog (Hh) target genes requires Cubitus interruptus, a 155 kDa cytoplasmic zinc finger p
87 a zinc-finger protein related to Drosophila cubitus interruptus, and Alx4(tm1rwm), a targeted null m
88 s receptor Patched, the transcription factor Cubitus interruptus, and the engrailed target gene that
89 Among them, hedgehog, patched, smoothened, cubitus interruptus, branchless, breathless, sprouty, de
90 ng the proteolytic processing of full-length Cubitus interruptus, Ci (Ci155), to generate a truncated
92 a coactivator for the transcription factors Cubitus interruptus, Dorsal, and Mad, and as a cosuppres
93 er eukaryotic transcription factors, such as Cubitus interruptus, NF-kappa B and sterol regulatory el
94 of hedgehog downstream transcription factor cubitus interruptus, the Drosophila homologue of vertebr
95 e that unlike the results seen with Gli3 and Cubitus Interruptus, the fly homolog of Gli, only a mino
96 An important gene epistatic to hedgehog is cubitus interruptus, which encodes the fly homolog of a
97 oundary between the engrailed-expressing and cubitus interruptus-expressing domains, indicating that
109 are zinc finger genes related to Drosophila cubitus interuptus, a component of the hedgehog signal t
110 heart and renal abnormalities, micrognathia, cubitus valgus, high-arched palate, short metacarpals an