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1  optimized as a series of dimeric compounds, culminating with 1 (cerastecin D), which exhibited antib
2 Belt, crustal thickening began at 240 Ma and culminated with 60-70-km-thick crust at 215 Ma.
3                These changes induced by cAMP culminated with a decrease in the glucose-dependent recr
4                              The interaction culminates with a collapse of B. graminis haustoria, the
5            The development program typically culminates with a comparative clinical efficacy study.
6                                   The review culminates with a description of future prospects for ta
7                                   The review culminates with a discussion of broader implications for
8 uage's usage and capabilities; the main text culminates with a final project in structural bioinforma
9 ional changes along the polymer backbone and culminating with a chain scission reaction.
10 etic observations in yeast mitochondria, and culminating with a detailed understanding of molecular m
11 d by a poly(Q) repeat of variable length and culminating with a proline-rich domain of 50 amino acids
12 different settings of increasing complexity, culminating with a real-world use-case in which our meth
13 ed a net increase over the last half-century culminating with a sharp spike in ad 1988-1990.
14 ficantly impaired in Rac1-deficient embryos, culminating with absence of intra-aortic clusters and fe
15 tion in migrating progenitors in the RMS and culminates with activity-dependent protein expression in
16 infected or malignant cells, their death can culminate with adaptive immune responses that are execut
17                                 This pathway culminates with addition of the C21-O-O* peroxyl adduct
18 matory process and the molecular events that culminates with an abnormal regulation of epithelial sod
19 cts with diabetes mellitus in particular, to culminate with arguments pro and con and a practical ris
20 g with alveolar epithelial dysregulation and culminating with changes in macrophage polarization.
21 m and doublesex specified non-neural tissues culminated with claims that fruitless was both necessary
22 hienopyridine series of Jak2 inhibitors that culminates with compounds showing 100- to >500-fold sele
23 erol depletion triggers a signaling cascade, culminating with contraction impairment and myofibril di
24 RNA-derived stress-induced RNAs (tiRNAs) and culminates with enhanced cell survival.
25 itions, beginning with spore germination and culminating with establishment of a systemic infection.
26 imbalance of cellular redox homeostasis that culminates with extensive lipid peroxidation and rapid p
27 leton-mediated FA growth and maturation thus culminate with FA traction oscillation to drive efficien
28                  In most eukaryotes, pairing culminates with formation of the proteinaceous synaptone
29                              The perspective culminates with future prospects for generating cyclic p
30 environment (the female reproductive tract), culminating with gamete fusion.
31 lecule in the hypoxic signaling cascade that culminates with HIF-1 activation.
32                    Our optimization strategy culminated with in vivo active RO7101556 (18B) having ex
33 t with the spatial progression of upwelling, culminating with increased D call density at the distal
34  weight oligomers found in fresh samples and culminates with increasing solvent protection of reporte
35 s to the formation of the phagocytic cup and culminates with ingestion of the foreign particle.
36 ion, immunology, and reproduction eventually culminated with Medawar's discovery of acquired immunolo
37  professional development while working, and culminating with mentoring the next generation.
38 tion of known asymmetric transformations and culminating with modern methods relying on unique electr
39                                  This report culminates with our evaluation of the suitability of Iso
40 change in its global structure, subsequently culminating with over-supercoiled form through in-path i
41                                         This culminated with potent 17beta-HSD3 inhibitors 23, 27, 31
42                                           It culminates with recommendations for advancing the curren
43    It is thought that this inhibition of AKT culminates with reduced glioma cell proliferation.
44                                 This program culminates with sliding of a nucleosome blocking the cor
45 physiological and epigenetic adaptations and culminating with slower long-lasting genetic ones.
46  it, a series of reversible changes occurred culminating with solidification of the SAM film at the l
47  of HMG-box Sox-family transcription factors culminating with Sox 17, which may be an obligate mediat
48 lex developmental programme in the mosquito, culminating with sporozoite invasion of the salivary gla
49 ogical change in the terrestrial ecosystems, culminating with tetrapod assemblages dominated in abund
50                                  The meeting culminated with the adoption of the special Gramado Decl
51 of ecological innovation and escalation that culminated with the Cambrian explosion.
52 tion into the in vivo propagation of (S)-ZNA culminated with the demonstration of the first synthetic
53                                    This work culminated with the discovery of PROTAC 23, which we dem
54 rity in order to improve intrinsic clearance culminated with the discovery of purinone 27 (AM-0902),
55 he first stage in a stepwise transition that culminated with the final shift to molluscan dominance i
56 k Death of 1348 and the later epidemics that culminated with the Great Plague of 1665, we estimate th
57                                  This effort culminated with the identification of a series of orally
58                                  The project culminated with the identification of the potent nanomol
59 an experimental tradition which has recently culminated with the Nobel Prize in Physics.
60 the target identification and validation and culminated with the preclinical tests on animal disease
61 ,000 y ago when people first left Africa and culminated with the settlement of East Polynesia, which
62                                    Our study culminates with the application of the tandem reaction s
63 RT recruitment to HIV-1 budding sites, which culminates with the assembly of the late-acting CHMP4, C
64                      This integrated pathway culminates with the direct phosphorylation of the crucia
65                                 This article culminates with the discovery of our first clinical cand
66 begins in the endoplasmic reticulum (ER) and culminates with the displacement of its inhibitory pro-d
67                          This process, which culminates with the ejection of the approximately 44 kb
68                  Preimplantation development culminates with the emergence of three distinct populati
69 coreceptor triggers the chain of events that culminates with the entry of the virus into the cell.
70 a mechanism of extracellular signalling that culminates with the formation of an aerial mycelium.
71 d at the top of a TMD chaperone cascade that culminates with the formation of Get3-TA protein complex
72 iation process known as cornification, which culminates with the formation of the epidermal barrier.
73 e homologous partner, a process that usually culminates with the formation of the synaptonemal comple
74             The interaction of sperm and egg culminates with the fusion of their cell membranes, trig
75 tion of arterial markers, is observed, which culminates with the generation of the supraintestinal ar
76                     Sustained UPR activation culminates with the induction of apoptosis.
77   The multienzyme pathway for heme formation culminates with the insertion of iron into a protoporphy
78                                RP biogenesis culminates with the joining of two large subcomplexes, t
79  the production of precursor transcripts and culminates with the loading of mature miRNA onto AGO2 by
80 y) is an evolutionary ancient mechanism that culminates with the lysosomal degradation of superfluous
81                       As such, our framework culminates with the novel aggregation method, cell-centr
82 f small molecules at extracellular sites and culminates with the opening of a membrane-embedded pore.
83 tidine diphosphate-choline (Kennedy) pathway culminates with the synthesis of phosphatidylcholine (PC
84 Ca2+i) initiate the flow of information that culminates with the upregulation of the stress response
85  and industry over the past several decades, culminating with the advent of and improvements in recha
86 ntification of five- to six-ringed aromatics culminating with the detection of coronene is accomplish
87 ic hematopoiesis occurs in successive waves, culminating with the emergence of hematopoietic stem cel
88 f mammals to mount adaptive immune responses culminating with the establishment of immunological memo
89 n is controlled by a transcriptional cascade culminating with the expression of the AraC-family regul
90  is a finely regulated physiological process culminating with the factor Xa (FXa)-mediated conversion
91 n pathway, starting with the free enzyme and culminating with the first irreversible step (decarboxyl
92 requires a coordinated multi-tissue response culminating with the formation of a complex vascular net
93 th rates in batch cultures during log phase, culminating with the onset of stationary phase.
94 acteria execute a complex regulatory pathway culminating with the production of virulence factors tha
95 s leading to nuclear import of NF-kappaB and culminating with the resynthesis of IkappaBalpha and sub
96 he Formative Period (1400 BCE to 500 CE) and culminating with the Tiwanaku state (500 to 1100 CE).
97 nt development of genome-editing technology, culminating with the use of CRISPR-Cas9 to generate nove
98 ion, the dynamic structure of membranes, and culminating with the use of various forms of spectroscop
99 minoacyl-tRNA.EF-Tu.GTP ternary complexs and culminating with translocation of A-site-bound peptidyl-
100                                The synthesis culminates with use of a modified Julia olefination for