ライフサイエンスコーパス: culture-negative

1 to subjects who were PCR or LCR positive but culture negative).

2 in 1 second (FEV1) were most likely to turn culture negative.

3 148 (82%) patients had sputum conversion to culture negative.

4 predictors of long-term sputum conversion to culture negative.

5 Three PCR-positive urine samples were culture negative.

6 Two PCR-positive saliva samples were culture negative.

7 in an additional 58% of specimens that were culture negative.

8 either blood culture positive or repeatedly culture negative.

9 dditional 11 specimens were PCR positive but culture negative.

10 t were fungal culture positive but bacterial culture negative.

11 polymicrobial, and one was gram positive and culture negative.

12 influenza B virus by Hexaplex; it was tissue culture negative.

13 lmitis, especially for those eyes that prove culture negative.

14 arted on therapy after the study began) were culture negative.

15 een specimens were BTUB 9/2-PCR positive and culture negative.

16 veral rabbits seroconverted but were PCR and culture negative.

17 ious cases of meningococcal disease that are culture negative.

18 processed specimens were often smear and/or culture negative.

19 , of which 160 were culture positive and 118 culture negative.

20 ow HMPV levels detected by PCR, but all were culture negative.

21 four cases were culture-positive and 26 were culture-negative.

22 the "missing 50%" of patients who are blood culture-negative.

23 N1 disease is predominantly neutrophilic and culture-negative.

24 isk of developing CDAD than patients who are culture-negative.

25 therapy, 14 (74%) had sputum samples become culture-negative.

26 al streptomycin, and they were treated until culture-negative 1 yr.

27 scites, 6 were culture positive (1.4%) and 9 culture negative (2.1%).

28 negative (29.9%), Gram positive (16.8%), and culture negative (30.7%).

29 ts: pp67 assay negative, 62 of 62 specimens; culture negative, 41 of 41 specimens; and PCR negative,

30 included 1 participant with endophthalmitis (culture negative), 9 with IOP more than 10 mm Hg greater

31 an additional 42 specimens that were direct culture negative (94.2% specificity) and 16 specimens th

32 ficity) and 16 specimens that were extracted culture negative (97.7% specificity).

33 Of 23 patients who are alive and were culture-negative a mean of 12.0 mo while receiving thera

34 ymptomatic and asymptomatic patients who are culture negative according to standard urine culture pro

35 icroscopy smear negative) as compared to PTB culture-negative (AFB microscopy smear negative) partici

36 All lymphocyte preparations were culture negative after 1 week.

37 ents and 94% of MRSA-colonized patients were culture negative after three consecutive negative cultur

38 Mice treated with clofazimine were culture-negative after 5 months, whereas all mice treate

39 all 1,312 aerobic bottles and 810 bacterial culture-negative anaerobic bottles.

40 transport/storage medium (50 specimens were culture negative and 50 specimens were culture positive

41 hoeae when it was either culture positive or culture negative and confirmed LCx positive.

42 detect HSV-1 DNA in ocular samples that are culture negative and contain rose bengal or lissamine gr

43 n 7 Xpert-positive retreatment patients were culture negative and potentially false positive.

44 Four clinical samples were Acanthamoeba culture negative and real-time PCR positive.

45 at was bacterial culture positive but fungal culture negative and three specimens that were fungal cu

46 using Lowenstein Jensen Medium with 46 being culture-negative and 24 being culture-positive.

47 Discrepant results between culture-negative and AMP CT-positive specimens were reso

48 Of 15 cases that were culture-negative and analyzed by other methods, 9 were P

49 wing resolution of the discrepancies between culture-negative and LCR-positive specimens, a diagnosis

50 clinical course of HRV culture-positive, HRV culture-negative and RT-PCR-positive, or HRV-negative co

51 The hisJ-generated amplicons from six culture-negative and six culture-positive specimens were

52 in this series-received an intravitreal tap (culture negative) and injection of antibiotics.

53 al-cord blood, we observed a new syndrome of culture-negative, antibiotic-responsive diarrhea not att

54 aOR 4.6, 95% CI, 2.1-10.0; p < .01) or blood culture-negative (aOR 2.9, 95% CI, 1.2-6.9; p = .02).

55 . cepacia in seven patients whose sputa were culture negative at this time.

56 All rats receiving sterile screws were culture-negative at euthanasia and displayed progressive

57 The sensitivity with 22 culture-negative BAL specimens from patients with IPA wa

58 ted diarrhoea (CDAD) are culture-positive or culture-negative before illness.

59 nvolvement detected using the BCID test with culture-negative blood and cerebrospinal fluid.

60 om non-S. aureus-positive blood cultures and culture-negative blood, accurately, rapidly and with hig

61 nia described four patients with persistent, culture-negative boils on the lower extremities.

62 ation with mass spectrometry (PCR/ESI-MS) to culture-negative bronchoalveolar lavage (BAL) fluid in o

63 virus when it was either culture positive or culture negative but Hexaplex and EIA positive.

64 was detected in all five samples which were culture negative but PCR positive.

65 ositive predictive value of Xpert MTB/RIF in culture-negative but clinically diagnosed PTB was 37.8%

66 c C. diphtheriae by culture and Elek, 6 were culture-negative but PCR-positive for diphtheria toxin g

67 mphoid tissues and vaginal mucosa were virus culture negative, but in 10 of 10 animals, SIV provirus

68 iven throughout, both regimens rendered mice culture negative by 5 months, and most mice did not rela

69 All subjects were culture negative by day 11, whereas one subject remained

70 e data were obtained from one smear-positive culture-negative case.

71 od and cerebrospinal fluid was positive in a culture-negative case.

72 phylococcus epidermidis in the vitreous of a culture-negative case.

73 ial infarction diagnoses in the CA-SABSI and culture negative cases respectively.Multivariable logist

74 -SABSI group at 10.9% (562/5157) compared to culture negative cases, 5.1% (521/10146) at 365 days (p

75 d 5157 CA-SABSI cases matched to 10146 blood culture negative cases.

76 confirmed cases and 41 Xpert MTB/RIF(R) and culture negative cases.

77 ture-positive cases compared to 3 of 42 (7%) culture-negative cases (P = .357).

78 d culture-positive cases lost 9.1 lines, and culture-negative cases lost 2.5 lines of vision (P < .00

79 d our previous experience with PCR/ESI-MS in culture-negative cases of infection prompted us to use t

80 The incidence of culture-negative cases of suspected endophthalmitis and

81 nt both culture-positive endophthalmitis and culture-negative cases of suspected endophthalmitis, the

82 ence of culture-positive endophthalmitis and culture-negative cases of suspected endophthalmitis.

83 Despite improved sensitivity, culture-negative cases remained; furthermore, culture ha

84 g detected a potential pathogen in 28 of 118 culture-negative cases, identifying staphylococci in the

85 Among 15 culture-negative cases, PCR was positive and sequencing

86 l signs differentiated culture-positive from culture-negative cases.

87 challenging for clinicians, particularly in culture-negative cases.

88 and identified potential pathogens in 33% of culture-negative cases.

89 ion and provided susceptibility data even in culture-negative cases.

90 ., Q fever serology, Bartonella serology) in culture-negative cases.

91 ctively; Xpert MTB/RIF detected 5 additional culture-negative cases.

92 f both blood culture-positive cats and blood culture-negative cats.

93 ation with mass spectrometry (PCR/ESI-MS) of culture-negative cerebrospinal fluid (CSF) in order to i

94 mass spectrometry (PCR/ESI-MS) to evaluate "culture-negative" cerebrospinal fluid (CSF) from a 67-ye

95 ra from culture-positive and 27 (64.3%) from culture-negative children reacted to C. pneumoniae antig

96 Xpert sensitivity in culture-negative children started on antituberculosis th

97 two reference standards-culture results and culture-negative children who were started on anti-tuber

98 single sera from 46 culture-positive and 42 culture-negative children with respiratory infection and

99 eviously applied to these 27 isolates and 46 culture-negative clinical samples (containing S. pneumon

100 s of Streptococcus pneumoniae infection from culture-negative clinical samples with the simultaneous

101 results were seen for four isolates and six culture-negative clinical samples, as PCR-RFLP could not

102 argeted PCR aid microbiological diagnosis in culture-negative clinical samples.

103 iagnosis of S. pneumoniae infection from 200 culture-negative clinical specimens sent to the laborato

104 Nonviable isolates and culture-negative clinical specimens were tested for the

105 Eight culture-positive and 40 culture-negative clinical specimens were tested.

106 otypes between viable/nonviable isolates and culture-negative clinical specimens.

107 After 2 months, 77% in the IL-2 group were culture negative compared with 85% of those receiving pl

108 mpared with 0% (0/13) of patients who became culture negative (converted).

109 bovis culture-positive cows (n = 12) than in culture-negative cows (n = 4).

110 Similarly, at advanced granuloma stages, culture-negative cows demonstrated significantly higher

111 In the early stages, culture-negative cows showed a significantly higher frac

112 firmed tuberculous meningitis, and 2900 with culture-negative CSF (including 1691 with CSF WCC of up

113 ition to a random selection of patients with culture-negative CSF and CSF WCC of up to 20 cells per m

114 When the analysis of patients with culture-negative CSF was restricted to those with known

115 ut they are not widely investigated in blood culture-negative, deep-seated candidiasis.

116 ive cavitation and were slower to convert to culture negative during treatment.

117 In blood culture-negative endocarditis (BCNE), 22% of cases remai

118 Prospective analyses of culture-negative endocarditis are needed to better asses

119 No patients with culture-negative endocarditis had organisms identified b

120 ral Bartonella spp. have been found to cause culture-negative endocarditis in humans.

121 re extremely rare and most often manifest as culture-negative endocarditis in patients with underlyin

122 considered in the differential diagnosis of culture-negative endocarditis in regions where it is end

123 Two cases of culture-negative endocarditis with cocci seen in valve v

124 d from patients with a clinical diagnosis of culture-negative endocarditis, 2, 4, and 2 were positive

125 oraxella osloensis should be tested in blood culture-negative endocarditis.

126 Changes in management for culture-negative endophthalmitis cases were performed ba

127 Change in clinical management for culture-negative endophthalmitis eyes was based on worse

128 lture-positive endophthalmitis and 1 case of culture-negative endophthalmitis occurred in the pegceta

129 The majority of culture-negative endophthalmitis samples did not contain

130 ble hypothesis for a pathogenic mechanism in culture-negative endophthalmitis.

131 ptimum in a high proportion of patients with culture-negative enteric fever.

132 Moraxella catarrhalis, S. pyogenes, and culture-negative episodes were also significantly reduce

133 infection (gram negative, gram positive, or culture negative) exerted a more or less identical respo

134 rmatory nucleic acid testing of GPP-positive/culture-negative extracts.

135 Culture negative, extrapulmonary disease was more common

136 ositive eyes compared with 0.59 (~20/80) for culture-negative eyes (adjusted difference, 0.394; 95% c

137 of 57 eyes (19%) compared with 3 of 54 (6%) culture-negative eyes (P = 0.03).

138 ure-positive eyes compared with 3 of 54 (6%) culture-negative eyes (P = 0.49).

139 s of bacterial endophthalmitis especially in culture-negative eyes.

140 known about the frequency of Xpert-positive, culture-negative ("false positive") results in retreatme

141 grade III or IV toxicities demonstrated were culture-negative febrile neutropenia, transient and reve

142 Amplification of 42 culture-negative fecal specimens (of 306 total specimens

143 One monkey that had been culture negative for a year after SIV inoculation became

144 Healthy volunteers were culture negative for AdV, and 96% were PCR negative.

145 All infants were culture negative for C. albicans at birth.

146 a strains were compared to controls who were culture negative for C. glabrata.

147 cimen was PCR positive for the vanA gene but culture negative for enterococci.

148 Only three of these rejected samples were culture negative for gram-negative CF pathogens.

149 ive for 1,594/1,612 sputum samples that were culture negative for M. tuberculosis (specificity, 98.9%

150 tive for pneumococcus than in those who were culture negative for pneumococcus (P<.05).

151 ses had active PTB, the remaining cases were culture negative for PTB.

152 lates clustered within communities that were culture negative for S. aureus.

153 Specimens GPP positive/culture negative for Salmonella originated in younger ch

154 All 6 patients had CSF and blood cultures negative for Cryptococcus neoformans and were r

155 treptococci (GABHS) and 61% of patients with cultures negative for GABHS.

156 a favorable status at 132 weeks, defined by cultures negative for Mycobacterium tuberculosis at 132

157 Among patients with cultures negative for Mycobacterium tuberculosis who wer

158 h acute peritonitis and discriminate between culture-negative, Gram-positive, and Gram-negative episo

159 -positive cows (low and medium shedders) and culture-negative healthy cows.

160 ex did not stimulate PMBC proliferation from culture-negative healthy cows.

161 erformed; 10 of the 16 discordant cases were culture-negative/histopathology-positive, while the rema

162 hree of the removed eyes received fresh were culture negative; however, all 5 demonstrated organisms

163 clusion, since Mur is not generally found in culture-negative human spleen, in future studies, these

164 as previously been reported to be present in culture-negative human spleen.

165 n indexes and anticipates diagnosis of blood culture-negative IAC.

166 Cases were subcategorized as culture negative if no significant growth was reported f

167 f clinical MSSA and MRSA strains and created culture-negative implants in the in vitro biofilm model.

168 Of these, 5 of 170 saliva culture-negative infants were positive by CB-PCR.

169 the identification of causal agents in blood culture-negative infective endocarditis.

170 is experiment, BPDA-PCR also identified five culture-negative liver samples as positive (41.7%).

171 etection of A. fumigatus genome in infarcted culture-negative lobes, by a greater number of mean geno

172 However, no differences were observed in culture-negative mastitis samples when compared to healt

173 capsule from blood samples for 32% of blood culture negative melioidosis patients in both cohorts an

174 ortality from pneumococcal, tuberculous, and culture-negative meningitis was high in this setting of

175 uberculous meningitis, and all patients with culture-negative meningitis with CSF white cell count (W

176 Fusobacterium nucleatum, in a patient with "culture-negative" meningitis and cerebral abscesses.

177 3 weeks resulted in a greater percentage of culture-negative mice.

178 roadly between culture-positive (n = 21) and culture-negative (n = 36) specimens.

179 We tested 132 blood cultures negative (n = 10) or positive (n = 97) for yeas

180 antibiotic use, especially in the setting of culture-negative neonatal sepsis.

181 Patients with culture negative neutrocytic ascites have a mortality ra

182 Culture negative neutrocytic ascites is a variant of spo

183 The 50 day in-hospital mortality rate in culture negative neutrocytic ascites was 39.41% (n = 67)

184 edictors of 50 days in-hospital mortality in culture negative neutrocytic ascites.

185 ted to intensive care unit with diagnosis of culture negative neutrocytic ascites.

186 was 13 days (range, 6-28 days), but all were culture negative (noninfectious) after 13 days.

187 lla catarrhalis, Streptococcus pyogenes, and culture-negative OM.

188 tabolically active, intact organisms in some culture-negative OME.

189 acterium tuberculosis; however, 5 (31%) were culture-negative on initial screening in Minnesota.

190 All 3 MDR TB cases were culture-negative on initial screening; these cases const

191 ents who have clinical typhoid fever but are culture negative or in regions where bacterial culturing

192 ee groups: AdV culture-positive samples, AdV culture-negative or bacterially contaminated samples fro

193 itive after storage for PCR testing), 71% of culture-negative or bacterially contaminated urines from

194 ve microbiologic culture than those who were culture negative (p = 0.0023) as well as those who died

195 tive fungal culture vs. 83 (+/- 25) in those culture-negative, (P < 0.01).

196 Culture negative patients had blood cultures collected a

197 septic, blood culture-positive or repeatedly culture-negative patients and four clinically nonseptic

198 f ultrafiltrates of clinically septic, blood culture-negative patients may be useful in recovery of t

199 We followed 60 incident NTM-positive and 99 culture-negative patients with CF for 15 months and asse

200 Of these culture-negative patients, five had sputum samples that

201 from AdV-infected patients, and 28% from AdV culture-negative patients.

202 1% (1181 of 2900) and 49% (1408 of 2900) for culture-negative patients.

203 Culture-negative PCR-positive samples contained a prepon

204 r of the 12 samples with discrepant results (culture negative, PCR positive) were confirmed to be pos

205 cts were identical and unique for each of 15 culture-negative, PCR-positive concordant partnerships.

206 utaneous anthrax outbreaks, the SETS yielded culture-negative, PCR-positive results.

207 Culture-negative, PCR-positive specimens that tested pos

208 Culture-negative, PCR-positive specimens that tested pos

209 Antigen was detected in six culture-negative, PCR-positive specimens.

210 Of 33 culture-negative/PCR-ESI-MS-positive specimens, 31 (93.9

211 that metabolically active bacteria exist in culture-negative pediatric middle-ear effusions and that

212 s were observed between culture-positive and culture-negative peritonitis.

213 panel detected Staphylococcus aureus in two culture-negative PJI cases.

214 n periprosthetic infections in particular in culture-negative PJIs with a positive histology or highl

215 Culture-negative PJIs, cases in which no cultures were o

216 ive PJIs and 37.8% (37/98) of sonicate fluid culture-negative PJIs.

217 was significantly (P=0.004) associated with culture negative pneumonia, and age (P=0.001) with cultu

218 Culture-negative pneumonia accounted for 61% of cases an

219 pneumonia hospitalizations, and N = 113 997 culture-negative pneumonia ED visits included in our ana

220 ency department (ED) visits for influenza or culture-negative pneumonia from 2005 to 2016.

221 s or hospitalizations for influenza, but not culture-negative pneumonia hospitalizations or ED visits

222 N = 57 522 influenza ED visits, N = 274 226 culture-negative pneumonia hospitalizations, and N = 113

223 3) Group 3- neonatal blood culture-negative presumed EONS with no IAI (n=7); 4) Gro

224 2) Group 2- neonatal blood culture-negative presumed EONS with positive IAI (n=16).

225 Defining the microbial etiology of culture-negative prosthetic joint infection (PJI) can be

226 ht be considered in some cases of apparently culture-negative prosthetic valve endocarditis.

227 ; 92.3%), and the sensitivities obtained for culture-negative PTB (82.4%) and EPTB (75.0%) in HIV-pos

228 In samples that were aerobic culture negative, pyrosequencing identified DNA of bacte

229 mL (3 SAU-positive and 3 NAS-positive) and 6 culture-negative quarter samples with <50,000 cells/mL w

230 Culture negative respiratory sample matrices were spiked

231 andida panel positive and myco/f lytic blood culture negative results, while 6 patients had T2Candida

232 onfirmed pertussis, those with PCR-positive, culture-negative results were older and more likely to h

233 Most patients in this series showed culture-negative results.

234 y staining were used to adjudicate chlamydia culture-negative results.

235 ield a recognizable pathogen sequence in any culture-negative sample, whereas BRiSK suggested the pre

236 suggested the presence of Streptococcus in 1 culture-negative sample.

237 e mean density of colonization was lower for culture-negative samples (3.14 log10 copies/mL) than for

238 imens culture positive for the virus than in culture-negative samples (33.3 cycles) (P < 0.0001).

239 11,224 IPD cases reported, 1,091 (10%) were culture-negative samples and 981 (90%) of these were lyt

240 DNA virus TTV was unexpectedly found in all culture-negative samples and some culture-positive sampl

241 BRiSK, 57.1% of culture-positive and 100% of culture-negative samples demonstrated the presence of to

242 tory of AdV culture-positive urines, and AdV culture-negative samples from patients without a history

243 hen tested in the Galileo assay, while 7% of culture-negative samples were assay positive, correspond

244 tection of amplification products, 12 of 181 culture-negative samples were positive for Legionella sp

245 Many intervening culture-negative samples were positive when tested by li

246 For culture-negative samples, mean cost-per-positive 16S PCR

247 osis was not detected in 25/25 (100%) of the culture-negative samples.

248 lture-positive samples and 17% (5/30) of the culture-negative samples.

249 arger amounts of antigen and DNA compared to culture-negative samples.

250 scence intensity levels than incubation with culture-negative samples.

251 g of Streptococcus pneumoniae are useful for culture-negative samples; however, there are limitations

252 n levels (15.39 ng/ml) than 24 patients with culture-negative sepsis (4.87 ng/ml), 44 with noninfecti

253 were also observed for culture-positive and culture-negative sepsis and lower respiratory tract infe

254 nd the duration of therapy for pneumonia and culture-negative sepsis was limited to 5 days.

255 However, accounting for the uncertainty from culture-negative sepsis, as many as 53.2% of readmission

256 The patient continued to have episodes of culture-negative sepsis; therefore, a computed tomograph

257 sepsis courses beyond 48 h, pneumonia, and "culture-negative" sepsis were selected as targets for an

258 ted children (19%) were treated for presumed culture-negative septic hip arthritis despite having pri

259 spiratory failure, pulmonary hemorrhage, and culture-negative septic shock.

260 urinary shedding of AdV in a pretransplant, culture-negative specimen and showed dissemination in a

261 GPP-positive/culture-negative specimen extracts tested positive using

262 Forty-nine of 52 culture-negative specimens came from patients on treatme

263 a second aliquot of the PCR/ESI-MS-positive/culture-negative specimens corroborated the initial find

264 useful for rapid typing of GAS isolates and culture-negative specimens during outbreak investigation

265 here was also complete concordance among the culture-negative specimens tested.

266 oth assays showed 95% specificity, with four culture-negative specimens testing as positive.

267 imurium and a second group of amplicons from culture-negative specimens that were more closely relate

268 on-time of flight mass spectrometry plus any culture-negative specimens that were positive by both in

269 e five MTD-positive, M. tuberculosis complex culture-negative specimens were considered truly positiv

270 Chlamydia culture-negative specimens were examined using DNA ampli

271 Discordantly LCR-positive and culture-negative specimens were further evaluated by tes

272 72 (74%) culture-positive and 7 culture-negative specimens were Xpert MTB/RIF positive.

273 Among the culture-negative specimens, 14(5%) specimens were positi

274 patients having smear-positive/MTD-negative/culture-negative specimens, decreased outpatient days of

275 Of the eight LCR-positive, culture-negative specimens, five were from patients with

276 imen and showed dissemination in a subset of culture-negative specimens, including BAL, blood, and bo

277 ot differ significantly between isolates and culture-negative specimens.

278 stool cultures, was detected in two of these culture-negative specimens.

279 the increased detection of PCR-positive but culture-negative specimens.

280 ens and detected Acanthamoeba in one of nine culture-negative specimens.

281 cterium bovis strain BCG DNA and to combined culture-negative sputum DNA and BCG DNA.

282 Reactivation of infection during this culture-negative state occurred spontaneously and follow

283 n 25 (89%) of the 28 sorbitol-MacConkey agar culture-negative STEC cases.

284 etecting and characterizing fungi in 7 of 10 culture-negative suspected fungal keratitis.

285 We describe the evaluation of culture-negative synovial fluid from a 3-year-old boy by

286 ying infection in suspected cases with blood culture-negative tests.

287 Further, the algorithm never called a culture negative that was determined to be positive by m

288 uginosa the year prior to ivacaftor use were culture negative the year following treatment; 88% (52/5

289 Conversely, 83% of culture-negative tissue and respiratory samples from uni

290 their sputa to negative, and 32 (82%) remain culture negative to date.

291 iagnosis was culture-confirmed tuberculosis, culture-negative tuberculosis, diseases other than tuber

292 Patients with culture-negative ulcers, viral etiology, coexistent ocul

293 ially tested as LightCycler PCR positive but culture negative using the Enterococcosel plate containi

294 initially tested as LightCycler positive but culture negative using the Enterococcosel plate containi

295 zation and mortality in empirically treated, culture-negative ventilator-associated pneumonia patient

296 th non-Nocardia etiology and those that were culture negative were excluded.

297 nd screened to be GBS III vaginal and rectal culture negative were randomized to receive III-TT conju

298 Discordant results (PCR or LCR positive, but culture negative) were confirmed by using a sequence inc

299 12.0 mo while receiving therapy, all remain culture-negative without therapy a mean of 19.1 mo.

300 antigens may persist in infected tissues of culture-negative women and provide one source for sustai