ライフサイエンスコーパス: curb

1 characterized by cracks, potholes, or broken curbs).

2 developed with the overfitting problem well curbed.

3 thholding a macrolide from patients with low CURB 65 scores, despite evidence that these patients hav

4 PSI had higher net benefit than mSOFA and CURB-65 for mortality, whereas mSOFA seemed more applica

5 pendently associated with an increase in the CURB-65 score (odds ratio [OR] 1.952 per point increase;

6 l and the Pneumonia Severity Index (PSI) and CURB-65 scores were measured on admission.

7 piratory rate, Blood pressure and age >= 65 (CURB-65) score was calculated to assess the severity of

8 a, Respiratory Rate, Blood Pressure and Age (CURB-65) score, and Pneumonia Severity Index (PSI) were

9 scrimination, followed by qSOFA, CRB, mSOFA, CURB-65, and PSI.

10 Taken together, the results reveal that RecG curbs a potentially negative effect of proteins that dir

11 , a Rho GTPase family member, is proposed to curb Abeta production.

12 consent can be harmful and are often used to curb adolescents' agency, including denial of adolescent

13 2s is a major area of investigation aimed at curbing allergic lung inflammation and exacerbation.

14 P regulatory circuit in the hexose transport curb, although other redundant pathways also contribute.

15 scans with the novel FAAH radioligand [(11)C]CURB and structural magnetic resonance imaging.

16 onists and Y2R antagonists may be useful for curbing and/or preventing binge drinking, protecting vul

17 mobility (ie, walking down steps, stairs, or curbs), and driving.

18 grow unless additional measures are taken to curb anthropogenic P emissions.

19 Curbing antibiotic use requires the development of simpl

20 tion and mandated by the Joint Commission to curb antimicrobial resistance.

21 PET/CT scanner after administration of (11)C-CURB ( approximately 350 MBq and approximately 2 mug).

22 adaptive immune mechanisms can accelerate or curb atherosclerosis.

23 tes of infection or tissue injury, likely to curb (auto)-inflammatory responses.

24 tion of APCs is a major regulatory mechanism curbing autoimmune responses and acts in concert with Fa

25 the importance of NOX-derived superoxide in curbing autoreactivity due, in part, to control of Treg

26 tion is key for efforts to develop agents to curb bacterial infections.

27 des the basis for taking effective action to curb biodiversity loss across the planet by 2020-an urge

28 turbation of lipid metabolism in these cells curbed brain metastasis development, suggesting a therap

29 effects of the cancer drug imatinib might be curbed by applying such premises.

30 hesize that the rate of BKV infection can be curbed by competitively preventing viral binding to cell

31 , exacerbating ErbB2-mediated tumorigenesis, curbed by pharmacological reduction of the elevated insu

32 Tumor growth can also be curbed by pharmacologically uncoupling bioenergetic path

33 ompetitive exclusion-overall biodiversity is curbed by the domination of "oligotroph" species.

34 V)2-mediated Ca(2+) rises are preferentially curbed by uptake into the endoplasmic reticulum and mito

35 dentify two small molecules that effectively curb cancer stem cell properties in a preclinical model.

36 rom deforestation and degradation (REDD) may curb carbon emissions, but the consequences for fire haz

37 ce, a focus on evidence-based practice and a curbed caring disposition.

38 esveratrol, restored apoptotic function, and curbed cell proliferation.

39 This curbed chemoresistance in KRAS-mutant pancreatic cancers

40 lexities of these factors will be pivotal in curbing CHIKV transmission.

41 yglutamine binding protein 1), significantly curbed cholestryl ester accumulation following treatment

42 obacco use trail behind the progress made in curbing cigarette consumption.

43 reenhouse gases at the source are crucial to curb climate change, but due to insignificant economic i

44 ion, and survival in secondary organs, which curbs CML development, progression, and metastatic disse

45 ount the first phase of IFN-I production and curb CMV replication in infected mice.

46 is a viable target for therapeutics aimed at curbing colon carcinoma metastasis.

47 axation levels and/or additional measures to curb consumption).

48 e affordable, and realised new provisions to curb costs (including tests of new health-care delivery

49 umber of Americans unless steps are taken to curb current trends.

50 d full property rights, will be effective at curbing deforestation.

51 d availability of mitochondrial material has curbed detailed biochemical and structural studies of th

52 Whey protein has been indicated to curb diet-induced obesity, glucose intolerance and delay

53 antly, myeloid-Klf6 deficiency significantly curbs diet-induced adipose tissue inflammation, obesity,

54 reatment is to control infection and thereby curb disease progression.

55 F receptor polarity and function in order to curb disease progression.

56 Curbing domestic emissions of particulates and precursor

57 y the successful development of ponatinib to curb drug resistance, we hypothesize that the incorporat

58 egatively regulate the RUNX1 super-enhancer, curbing EBNA2 activation.

59 be a potential therapeutic target in SIRS by curbing effector cytokine production from CD8(+) T cells

60 ern transportation, which despite efforts to curb emissions, continues to play a critical role in env

61 Despite 20 years of effort to curb emissions, greenhouse gas (GHG) emissions grew fast

62 hat acylated ghrelin stimulates appetite and curbs energy expenditure during deficient energy intake,

63 effort to develop a clean energy economy and curb environmental pollution incentivizes the use of hyd

64 Key to identifying methods for curbing excess deposition of extracellular matrix is a b

65 of ethanol may help identify drug targets to curb excessive alcohol consumption.

66 tage for the host bacteria is that the SaPIs curb excessive phage growth while enhancing their gene t

67 Here, we show that TMEM16F is required to curb excessive T cell responses in chronic infection wit

68 ibition of PUMA expression may be useful for curbing excessive cell death associated with tissue inju

69 selective FoxO6 inhibition is beneficial for curbing excessive hepatic glucose production and improvi

70 subset of immune cells that are dedicated to curbing excessive immune activation and maintaining immu

71 ders can collaborate to contain drug prices, curbing expenditures overall while expanding health care

72 In vivo studies revealed that Retro-2 curbed experimental L. amazonensis infections in a dose-

73 sized that increasing hunger intensity would curb expression of social behaviors such as mating or te

74 NA-directed Nedd4.2 gene silencing could not curb fatty acid-induced loss of SNAT2 adaptation.

75 EP2 and EP4 agonism also curbed FcepsilonRI-mediated degranulation of human MCs.

76 commitment of lung epithelial progenitors by curbing Fgf10 and beta-catenin signaling.

77 This indicates that if governments act on curbing fire usage and effectively plan public health pr

78 ack loop is similar to the "hexose transport curb" first described almost 30 years ago.

79 ly likely to thrive if people join forces to curb free riding and punish their non-contributing peers

80 ce, restricting future N pollution will help curb further cyanobacterial dominance in lakes both dire

81 To curb further extinctions and develop effective mitigatio

82 eed for judicious agricultural management to curb future CH(4) emissions.

83 Consequently, immediate global action to curb future warming is essential to secure a future for

84 l tumor-suppressive effect of Pol epsilon in curbing genome re-arrangements.

85 ene therapy provide an intriguing option for curbing glioma related deaths.

86 or, free fatty acid receptor 1 (Ffar1), that curbs glucose uptake when fatty acids are available.

87 Policies that attempt to curb greenhouse gas emissions, allocate emissions rights

88 ikely too optimistic, increasing the need to curb greenhouse gas emissions.

89 iferation of human C-PVR cells in vitro, and curbed growth of freshly isolated human PVR membranes in

90 The donor ACP (CurB) had high affinity for the enzyme (Kd = 0.5 muM) an

91 opagation and are potential drug targets for curbing herpesvirus infections.

92 coupling, might be of therapeutic value for curbing HF-exacerbating hyperaldosteronism.

93 Nrg4 gene transfer curbed HFD-induced hepatic steatosis by inhibiting lipog

94 ownregulated cell surface expression of MET, curbing HGF-independent MET activity, and engaged natura

95 for tyramine, and suggest that it serves to curb high levels of courtship activity through functioni

96 indicate that inhibiting inflammation could curb HIV propagation.

97 velopment of new microbicides or vaccines to curb HIV-1 infection at its earliest stages during mucos

98 ccines to prevent MTCT.IMPORTANCE Efforts to curb HIV-1 transmission in pediatric populations by anti

99 tegies to exploit miRNAs therapeutically for curbing HIV-1 infectivity, replication and latency since

100 dental prescribing is warranted in order to curb iatrogenic opioid morbidity and mortality.

101 worked to balance the ocean N budget and to curb ice age-interglacial change in the N inventory.

102 Blocking experiments demonstrated that regDC curb IFN-gamma secretion by NK cells through a dominant

103 country, or individual to fish sustainably, curb illegal fishing, or create large marine reserves as

104 e, often limiting pathogen-specific cells to curb immune-mediated damage.

105 th and duration of immune responses, thereby curbing immune-mediated tissue damage, regulating resolu

106 rontal cortex (PFC) plays a critical role in curbing impulsive behavior, but the underlying circuit m

107 with positron emission tomography and [(11)C]CURB in 22 healthy control subjects and ten chronic cann

108 t absence of CaMK4 restores IL-2 production, curbs increased T cell activation, and augments the numb

109 ght to improve outcomes, decrease costs, and curb increases in antimicrobial resistance around the wo

110 r measurements to demonstrate its success in curbing increases in UV radiation.

111 These changes curbed infarct expansion and preserved left ventricular

112 closure to be an effective control policy to curb infestation prevalence.

113 in enhancing the ability of chondrocytes to curb inflammation in diseased joints.

114 Monocyte ablation aimed to curb inflammation would therefore likely interfere with

115 nhibiting GSDMD is an attractive strategy to curb inflammation.

116 ating cyclic (aza)peptide CD36 modulators to curb inflammation.

117 Most of the known regulatory mechanisms that curb inflammatory gene expression target pre-transcripti

118 A2a agonists may be effective at curbing inflammatory lung tissue damage.

119 eroceptive cravings to cognitive control for curbing internal urges.

120 Modeling reveals that curbing interstate travel when the disease is already wi

121 different families of viruses; while TRIM56 curbs intracellular YFV/DENV2 RNA replication, it acts a

122 d involve more informed DLS perturbations to curb intractably problematic habits.

123 atty acid amide hydrolase enzyme probe (11)C-CURB is within the same range as other radiotracers labe

124 (11)C-carbonyl-URB694 ((11)C-CURB) is a novel (11)C-labeled suicide irreversible radi

125 Valorization of industrial residues curbs issues related to food security and environmental

126 valuable products is a pragmatic solution to curb its accumulation in the atmosphere.

127 igh priority for deciphering its mystery and curbing its spread.

128 vels with anemia and make further efforts to curb lead pollution and childhood anemia.

129 irm that increased MAFG signaling during DIO curbs lncRNA expression.

130 Several BRAF inhibitors aimed at curbing MAPK pathway activity are currently in advanced

131 w therapeutic opportunities that may help to curb melanoma metastasis.

132 nly molecule BIM, while BCL6 was required to curb MLL-induced expression of BIM.

133 o its (i) deployment in worldwide efforts to curb mosquito-borne diseases, (ii) causation by bacterio

134 ption domain-associated protein (TRRAP), and curbed mTOR signaling, indicating that Tel2 affects all

135 ers and the importance of these findings for curbing N2O emissions.

136 ncluding cell-cycle arrest and apoptosis, to curb neoplastic growth.

137 all molecule inhibition of Wnt, were able to curb NF2 deficiency-elicited cell proliferation at the c

138 sufficiently high antibody concentration to curb nicotine distribution to the brain.

139 China has regarded curbing non-prescription sales of antibiotics at communi

140 for more effective prevention strategies to curb nosocomial respiratory virus outbreaks.

141 Continued public health efforts to curb obesity prevalence are needed to reduce the project

142 iting of RNA bases(5), and created selective curbing of unwanted RNA editing (SECURE)-BE3 variants th

143 With governments' increasing efforts to curb opioid prescription use and limit dose below the Ce

144 l cholesterol in regions with decline and to curb or prevent the rise in Asian populations and elsewh

145 Interventions and policies that can curb or reverse the increase, and mitigate the health ef

146 reducing greenhouse gas emissions, and thus curbing, or even reversing, the increase in their atmosp

147 ubliminal signals arising from the gut would curb our uncontrolled desire for calories.

148 s on minimum response capabilities needed to curb outbreaks, and predictions of endemic states when c

149 Most immediately, it can have a role in curbing outbreaks of hepatitis E in humanitarian crises.

150 Using this scaffold we ideate strategies to curb overgeneralization of fear in PTSD.

151 its modulation has proven to be effective in curbing pathologic angiogenesis in experimental oxygen-i

152 In the present study, we show that SOCS3 curbs pathologic angiogenesis.

153 This curbs phagocyte secretion of IL-23, a cytokine controlli

154 ocytes, attenuated infarct inflammation, and curbed post-MI left ventricular remodeling.

155 ncing of endothelial cell adhesion molecules curbed post-MI monocyte recruitment to the remote myocar

156 ntary approaches to improve the efficacy and curb potential toxicities of this approach.

157 ed pretreatment activity calculation methods curb potentially achievable tumor-absorbed dose values.

158 of Amazonian freshwater ecosystems cannot be curbed presently because existing policies are inconsist

159 ssociation with decreased number of appetite-curbing pro-opiomelanocortin (POMC) neurons; whether the

160 The transcriptional regulator STAT3 curbs pro-inflammatory cytokine production mediated by N

161 Regulatory actions have curbed production of legacy compounds such as perfluoroo

162 , synthetic challenges have, until recently, curbed progress.

163 be instrumental for therapeutic discovery to curb prometastatic processes.

164 Curbing resolvase activity and establishing a hierarchy

165 estimate the radiation dosimetry from (11)C-CURB scans in humans.

166 may offer methods for enrollment feedback to curb selection bias in recruitment.

167 several practical steps that can be taken to curb sexual harassment in academia.

168 red imatinib as an agent to treat GISTs with curbed side effects and reveal a bottom-up approach to c

169 st of continuing to develop new solutions to curb spending on health care and reduce waste in the Uni

170 finasteride as a novel therapeutic avenue to curb symptom fluctuations in TS.

171 the site of infection, which is essential to curb systemic virus spread.

172 draining the primary site of infection thus curbing systemic viral spread.

173 eiotropic cytokine that can both promote and curb Th2-dependent allergic responses.

174 tening antibiotics to improve cure rates and curb the alarming emergence of drug resistance is the ma

175 Cost-effective strategies to curb the burden of diabetes among patients with active t

176 t young people, families, and communities to curb the commencement of smoking among children and adol

177 and TasP in real-world settings, efforts to curb the continuing HIV epidemic through use of these no

178 One way to curb the development of antibiotic resistance is to desi

179 Pediatricians should help curb the epidemic through prevention and the usual pedia

180 ding active surveillance components, to help curb the epidemic.

181 vaginal products therefore is needed to help curb the epidemic.

182 actors are warranted in all world regions to curb the future breast cancer burden.

183 and expand the use of such interventions to curb the global epidemic of type 2 diabetes and its cons

184 ent as prevention" has emerged as a means to curb the global HIV epidemic.

185 e promising new field of immunometabolism to curb the global obesity and T2D epidemics.

186 To be able to curb the global pandemic of physical inactivity and the

187 accination strategies are urgently needed to curb the global spread of this virus, and the developmen

188 massive investment in HIV treatment, and to curb the global TB burden.

189 injection-risk behaviors simultaneously may curb the growing HIV epidemic in the Mexico-US border re

190 eproducibility of (bio)chemical research and curb the growing trend of structural misassignments.

191 iciency virus (HIV)-1 are urgently needed to curb the growth of the acquired immunodeficiency syndrom

192 the general population and whether they can curb the growth of the infected group while keeping the

193 Treatment interventions to curb the HCV epidemic among HIV-infected men who have se

194 te new guidelines that will serve efforts to curb the hepatitis C epidemic, rather than frustrate the

195 ivity in reviewer decisions, which serves to curb the herding process, can be beneficial for the scie

196 -term health-care and prevention services to curb the HIV epidemic and improve the quality of life of

197 immunodeficiency virus (HIV) transmission to curb the HIV epidemic, there is a need to develop evalua

198 therapeutic vaccine offers the best hope to curb the HIV-AIDS epidemic gripping sub-Saharan Africa,

199 AIDS (UNAIDS) has set a "90-90-90" target to curb the human immunodeficiency virus (HIV) epidemic by

200 bilitation programs after transplantation to curb the muscular loss and (ii) systematic attention to

201 rgence of resistance and support the need to curb the nontherapeutic use of medically important antim

202 pneumoniae colonization has the potential to curb the number of HAIs.

203 division but turn on asymmetric division to curb the number of ISCs when proinflammatory response ca

204 ioidergic function might thus be critical to curb the obesity epidemic.

205 exclusivity of breastfeeding are unlikely to curb the obesity epidemic.

206 products may limit their appeal to youth and curb the onset of cigarette smoking.

207 hways can be targeted to opposite effect: to curb the over-exuberant immune response.

208 erapeutic discovery efforts are paramount to curb the pandemic spread of this zoonotic virus.

209 ates critical neurotrophic delivery that can curb the rapid progression of neurodegeneration while im

210 epidermal progenitor cells where it acts to curb the rate of proliferation as well as in their proge

211 inflammatory cytokines and chemokines and to curb the recruitment of inflammatory myeloid cells into

212 Effective strategies are needed to curb the reemerging epidemic of HDV infection in these h

213 al food ingredients are critically needed to curb the rise in metabolic disease.

214 n to Combat Antibiotic-Resistant Bacteria to curb the rise of "superbugs," bacteria resistant to anti

215 Visionary political leadership is needed to curb the rise of MDR and XDR tuberculosis worldwide, thr

216 in the most affected countries in Africa to curb the rising burden of disease and control future out

217 tion and other preventive therapies may help curb the rising incidence of HF.

218 chemotherapy, and radiation is warranted to curb the risk of metastasis and disease-specific mortali

219 Antimicrobial Stewardship Programs (ASP) to curb the selection of AMR but, there is a lack of data c

220 antimicrobial stewardship programs (ASPs) to curb the selection of AMR, but there is a lack of data c

221 'lockdown' of all non-essential services to curb the spread of COVID-19.

222 nforming isolation decisions, and helping to curb the spread of disease.

223 as potential supplements for microbicides to curb the spread of HIV-1 through sexual contact.

224 suitable combination of NPIs is necessary to curb the spread of the virus.

225 s that warrant further investigation to help curb the spread of these potentially lethal organisms.

226 n urgent need for antivirals and vaccines to curb the spread of these viruses.

227 To curb the staggering health burden attributed to air poll

228 th an adequate supply of mitochondria and to curb the transmission of deleterious mtDNA variants.

229 emented a number of innovative strategies to curb the transmission of wild poliovirus (WPV) in the co

230 In an effort to curb the treatment costs of this common disorder, ration

231 ivin A in skeletal muscle, whereas activin A curbed the IL6-induced acute-phase response in liver.

232 adrenocorticotropic hormone and cortisol and curbed the meal-related rise in plasma glucose.

233 Inclusion of unsaturated R groups curbed the overall reactivity (varphi = 1 to 2 orders of

234 anoemulsion that when administered topically curbed the progression of disease in a novel rabbit mode

235 rohibit commercial transplants in India have curbed the trade.

236 but possible complications have temporarily curbed the use of this vaccine.

237 nal innovation and purifying selection, thus curbing the concentration imbalance arising from gene du

238 rent multi-faceted preventive strategies for curbing the epidemic of diabetes in the older population

239 Curbing the epidemic will require maximizing the impact

240 mic, rendering these measures ineffective at curbing the epidemic.

241 he role of treatment as prevention (TasP) in curbing the epidemic.

242 he transcription of lytic IE1/IE2 mRNA while curbing the expression of latency-associated UL138 mRNA.

243 shorten antibiotic therapy is imperative in curbing the global tuberculosis epidemic.

244 By curbing the information-degrading effects of cell-to-cel

245 did not find evidence of ribosome collisions curbing the protein output of yeast transcripts, either

246 t VGF is required for the effects of LiCl in curbing the response to amphetamine.

247 While public health policies aimed at curbing the underlying causes of the obesity epidemic ar

248 nce, a focus on evidence-based practice that curbs the ad hoc repertoire of the caring disposition.

249 ay represent an evolutionary adaptation that curbs the amplified infection risk after CNS trauma, due

250 L-27R-/- mice, these data suggest that IL-27 curbs the development of immunopathology by limiting par

251 y a Toll-like receptor agonist that not only curbs the host inflammatory response but also eliminates

252 ed either epithelial cadherin (E-Cad), which curbs the malignant behavior of tumor cells, or neuronal

253 To investigate whether ATXN1[30Q]-D776 curbs the progressive disease in ATXN1[82Q]-S776 mice, w

254 , allotransplanted and autochthonous tumours curb their growth, thus extending animal survival by 37%

255 fects, in particular emesis and nausea, have curbed their clinical utility.

256 ceae to pinpoint possible control points for curbing their spread.

257 n intervention known as self-affirmation can curb these negative outcomes.

258 , we discuss proposed interventions aimed at curbing these adverse trends, management approaches that

259 aggressive patient outreach programs now to curb this anticipated problem.

260 on gill poxvirus in Atlantic salmon may help curb this disease and provide comparative knowledge.

261 g studies and begun to develop approaches to curb this growth.

262 al activation of an inhibitory pathway might curb this initial steep rise in firing rate.

263 infection control practices is essential to curb this nosocomial, iatrogenic disease.

264 eling and management, critically required to curb this rare disorder in the families.

265 ical interactions in silicate-rich rocks may curb this transport drastically and even inhibit it alto

266 cation about the low risk of CBC may help to curb this trend.

267 a vaccine is the best long-term solution for curbing this global epidemic.

268 principle that epigenetic interventions can curb TNR expansions.

269 ontinuous supply of potent killer T cells to curb Toxoplasma gondii growth during latency.

270 s despite global public health strategies to curb transmission by testing symptomatic patients and so

271 ired for leprosy control to reduce cases and curb transmission of Mycobacterium leprae.

272 s crucial for the design of interventions to curb transmission.

273 with a positive test result could profoundly curb transmission.

274 the populations at risk will be essential to curb transmission.

275 s manifest would allow targeted treatment to curb transmission.

276 sidering the easing of restrictions aimed at curbing transmission.

277 , fair, and socially responsible solution to curb transmissions of airborne viruses.

278 osis, but the ability of diagnostic tests to curb tuberculosis transmission is dependent on multiple

279 re appealing candidates to reprogram TAM and curb tumor-mediated immunosuppression, thereby empowerin

280 Furthermore, treatment with anti-TREM2 mAb curbed tumor growth and fostered regression when combine

281 e efficacy of RFA in producing local cure or curbing tumor progression during the waiting period.

282 ted with poor prognosis, and IL-17A blockade curbs tumor progression in preclinical models of CRC.

283 Inactivation of PIN1 function conversely curbs tumour growth and cancer stem cell expansion, rest

284 In an attempt to curb unauthorized migration, many states have considered

285 ods (fruits, vegetables, legumes, and nuts), curbing unhealthy foods (saturated fats, trans fats, ref

286 ination and accurate influenza diagnosis may curb unnecessary antibiotic use and reduce the global th

287 rtant to understand what mechanisms exist to curb unwanted activation.

288 Our findings suggest that curbing US assistance to family planning organisations,

289 ong e-cigarette regulation could potentially curb use among youth and possibly limit the future popul

290 These data show that Abr and Bcr normally curb very specific functions of mature tissue innate imm

291 pression of a subset of antiviral genes that curb viral replication until mitochondrial MAVS can indu

292 alpha/beta interferon receptor is needed to curb viral replication, it is dispensable for the induct

293 pe I interferon (IFN) is a key cytokine that curbs viral infection and cell malignancy.

294 , thereby slowing down the host's ability to curb virus replication and induce adaptive immunity.

295 on.IMPORTANCE Host cells mount a response to curb virus replication in infected cells and prevent spr

296 imultaneously suppress virus replication and curb virus-induced detrimental host immune responses in

297 In some cases, cell death curbs virus replication.

298 (11)C-CURB was well tolerated in all subjects, with no radiotr

299 formance by emission standards, model years, curb weights, engine loads, manufacturers, vehicle age,

300 Health and social policies are needed to curb widening life expectancy inequalities, help deprive