ライフサイエンスコーパス: curing

1 arise again in the cured strain (reversible curing).

2 thermosets maintain their malleability after curing.

3 imately 1.5 h, not including overnight epoxy curing.

4 r1p, with both proteins needed for efficient curing.

5 eactions throughout the whole process of dry-curing.

6 [URE3], and Hsp42p aids Btn2 overproduction curing.

7 reby providing a powerful system for protein curing.

8 H-bonding containing monomer during network curing.

9 ccurring in the different muscles during dry-curing.

10 evented Sup35 fragmentation and caused prion curing.

11 p is a specific Hsp40 important for [PSI(+)] curing.

12 saggregation does not adequately explain the curing.

13 portant for the contribution of ubiquitin to curing.

14 g approximately 1.4 microm thick films after curing.

15 ubstrate to Hsp70 had little or no effect on curing.

16 posites became more opaque or translucent on curing.

17 e need of long-duration and high-temperature curing.

18 nto liquid crystal elastomers by ultraviolet curing.

19 performed 0, 1, 3, 5, and 10 min after light curing.

20 30 KHz) during and up to 10 min after light curing.

21 f crosslinking, gel time, degree and rate of curing.

22 and the weaker the variant, the greater the curing.

23 in the acute mouse model of trypanosomiasis, curing 3/4 or 4/4 animals at 4 x 5 mg/kg.

24 highly significant improvement in survival, curing 33% to 90% of the animals, even at relatively low

25 the bispecific outperformed the SA approach, curing 35% more mice overall (P < .004).

26 Here, we investigated the effects of curing (37 degrees C for 3 days) and storage at low-temp

27 2 in MM and NHL xenograft models, ultimately curing 80% of mice at optimal doses.

28 The first step in curing a disease is being able to detect the disease eff

29 bination immunotherapies that are capable of curing a majority of tumors in experimental settings typ

30 e of properties have been prepared by simply curing a mixture of diols and triols with bifunctional p

31 of a particular intervention in managing or curing a specific condition, there exists a substantial

32 l dimethacrylate, which showed a unique self-curing ability.

33 tion, thus separating filament cleavage from curing activities.

34 The curing activity of Hsp104 thus constitutes an antiprion

35 erivatives for understanding, diagnosing and curing AD.

36 n to achieve PVAI is a promising approach to curing AF.

37 s prepared from widely used PDMS pre-polymer:curing agent ratios (10:1, 15:1 and 20:1), and these lea

38 a diepoxy comonomer, and a dicarboxylic acid curing agent.

39 ection, has been proposed as one approach to curing AIDS.

40 rve as a novel and effective platform toward curing AIDS.

41 excellent antitrypanosomal efficacy in vivo curing all infected animals in the STIB900 acute mouse m

42 antitrypanosomal efficacy than melarsoprol, curing all infected mice.

43 lantation (SCT) has been proven effective in curing AML by allowing for the administration of otherwi

44 Mermessus fradeorum and then used antibiotic curing and controlled mating assays to demonstrate that

45 time of the 3D model, and including time for curing and drying of materials, this procedure can be co

46 chemistry is employed to achieve rapid light-curing and minimize residual monomer of the lead materia

47 Curing and storage for up to 8 months did not significan

48 ere collected at different stages during dry-curing and submitted to magnetic resonance imaging (MRI)

49 l interactions of Ydj1p with Hsp70 abolished curing, and the J domain alone cured [URE3].

50 In this study, after successfully curing APEC of its plasmids, we were able to investigate

51 l production, antimicrobial therapy, and for curing arthropods infected with bacterial endosymbionts

52 microbial activity in the in vivo C. elegans curing assay.

53 We also find curing associated with cell division.

54 nstrating cross-linking of the polymer after curing at 120 degrees C.

55 r precursors with block copolymer templates, curing at 140-180 degrees C, and calcination to remove t

56 formulation and naturally dried followed by curing at 180 degrees C.

57 l congeners were more active than 1 in vivo, curing at least 2/4 infected animals in the acute mouse

58 XPL can be topically applied, rapidly curing at the skin interface without the need for heat-

59 We propose a new paradigm focused on curing atherosclerosis early in the course of the diseas

60 sign feature in the adhesive performance and curing behavior of this bioinspired thermoset.

61 ith severe restrictions on biocompatibility, curing behavior, esthetics, and ultimate material proper

62 only 0.4-0.5% of Hg escaped from mixing and curing BFD-added cement.

63 or stimulated a systemic antitumor response, curing both tumors.

64 ed with preventing, treating, and ultimately curing breast cancer are addressable in the laboratory,

65 hat elevating free ubiquitin levels enhances curing, but it did not overcome inhibition of curing cau

66 ability of excess Ssa to counteract [PSI(+)] curing by excess Hsp104.

67 ces de novo [PSI(+)] appearance and prevents curing by excess Hsp104.

68 +)] prion oligomers increase during [PSI(+)] curing by excess Ssa1.

69 Therefore, curing by Hsp104 overexpression depends on both the trim

70 uction, cures [PSI+], and potentiates [PSI+]-curing by Hsp104 overexpression.

71 oles of Hsp70, Sti1, and Hsp90 for efficient curing by overexpressed Hsp104 and provide evidence supp

72 n of BTN2 and CUR1 stabilizes [URE3] against curing by several agents, produces a remarkable increase

73 Btn2p nor Cur1p is needed for overproduction curing by the other.

74 , were exclusively identified at 9 months of curing by using both methodologies so that these peptide

75 In livers of susceptible but self-curing C57BL/6 mice, intracellular Leishmania donovani i

76 roots for the major challenge of effectively curing cancer patients.

77 nd create public health benefits on par with curing cancer.

78 yzed the lack of progress in explaining and "curing" cancer by examining the merits of the premises t

79 uring, but it did not overcome inhibition of curing caused by Hsp90 defects, suggesting that Hsp90 ma

80 40 chaperone, Sis1, rescues this toxicity by curing cells of [PrD(157)(+)].

81 Curing CHC was associated with a reduction in MR among c

82 lthough important advances have been made in curing childhood cancer in the last several decades, lon

83 portant component of a treatment regimen for curing chronic hepatitis B virus (HBV) infection.

84 ly, we find both drugs are more effective at curing chronic infections, judged by treatment duration

85 A major obstacle to curing chronic myeloid leukemia (CML) is the intrinsic r

86 axomicin to be noninferior to vancomycin for curing Clostridium difficile infection (CDI) and superio

87 The success of FMT in curing Clostridium difficile infection (CDI) is well est

88 Curing CML depends on the eradication of LSCs.

89 Here we explore the possibility of curing colour blindness using gene therapy in experiment

90 oncentration of PMMA, spin coating speed and curing condition, we obtained very smooth and ultrathin

91 ns about the influence of the components and curing conditions on the mechanical properties of the su

92 rogramming and highlighted the potential for curing degenerative retinal diseases from intrinsic cell

93 dental amalgam, dental composites and light curing, dental adhesives and dental cements, ceramics, a

94 se heating procedure, independent of nitrite-curing, depending strongly on the fecal inoculum used.

95 he current short wavelength initiators limit curing depth and efficacy because they do not absorb wit

96 However, plasmid curing did not affect their tolerance to gastro-intestin

97 utaneous leishmaniasis is an ultimately self-curing disease for which systemic therapy with pentavale

98 The majority ranked developing medicines and curing diseases as the most important contributions of s

99 r the Bayonne ham is directly related to its curing due to the salt used in process coming from the n

100 nd Stem cell factor and offers the chance of curing early-stage disease while preventing neuroendocri

101 Concomitantly, qPCR analysis showed that curing enhanced upregulation of the main structural and

102 To qualitatively reproduce the GdnHCl curing experiment, aggregate replication must not be com

103 This result is based on the study of prion curing experiments, as well as the phenomenon of colony

104 Here, we conduct curing experiments, intra- and interspecific crosses, cy

105 continued to propagate after composite light curing finished.

106 Light cure is a popular mode of curing for dental adhesives.

107 enchymal stem cells') hold the potential for curing generalized skeletal diseases, their clinical eff

108 el TSHR Ag-specific immunotherapies aimed at curing Graves' disease in humans.

109 Nitrite-curing had an antioxidant effect during digestion, but t

110 exuded adhesive substances, favor subsequent curing (hardening) via formation of an adhesive film, an

111 materials that adopt a permanent shape upon curing-have a key role in the modern plastics and rubber

112 The central challenge in curing HBV is eradication of the stable covalently close

113 Indeed, curing HCV infection with an oral medication is now real

114 may represent a viable treatment option for curing HCV infection.

115 es has been paramount to the VA's success in curing HCV infection.

116 ietic stem cell transplantation (alloSCT) in curing hematologic malignancies is due to a graft-versus

117 These findings lay the foundation for curing hemophilia A by NHEJ knock-in of BDDF8 at Alb int

118 Curing HIV infection has been impossible, with the excep

119 Curing HIV infection has been thwarted by the persistent

120 Interventions aimed at curing HIV infection have the potential to improve overa

121 Recent case reports have suggested that curing HIV infection is possible, renewing excitement ab

122 Currently, a major barrier to curing HIV infection is the generation of tissue-associa

123 Curing HIV infection will require the elimination of a r

124 d individuals and that is a major barrier to curing HIV infection, the in vivo proliferation of laten

125 viral persistence and hence be a barrier to curing HIV infection.

126 the intact proviruses that are a barrier to curing HIV infection.

127 therapy (cART) presents a major barrier for curing HIV infections.

128 nfected CD4+ T cells is the major barrier to curing HIV, and has been extensively studied in this lig

129 common with ART and is the major barrier to curing HIV-1 infection.

130 emory CD4(+) T cells is the major barrier to curing HIV-1 infection.

131 tic implications with respect to the goal of curing HIV-1 infection.

132 CD4(+) T cells serves as a major barrier to curing HIV-1 infection.

133 re critical to understanding the barriers to curing HIV-1 infection.

134 Elimination of this reservoir is critical to curing HIV-1 infection.

135 ells (rCD4 cells), posing a major barrier to curing HIV-1 infection.

136 combination antiretroviral therapy and make curing HIV-1 infections a major challenge.

137 The barrier to curing HIV-1 is thought to reside primarily in CD4(+) T

138 rapies (ART) and remain the major barrier to curing HIV-1.

139 latent HIV-1 reservoir, a major obstacle to curing HIV-1.

140 s and therefore represent a major barrier to curing HIV-infected individuals.

141 ate complex immune-based approaches aimed at curing HIV-infection, particularly relevant to the pipel

142 IV-1 provirus represents a major obstacle to curing HIV.

143 on is widely regarded as the main barrier to curing HIV.

144 ish a latent infection presents a barrier to curing HIV.

145 serve as new targets for therapies aimed at curing HIV.

146 (TPR) interaction motif was dispensable for curing; however, cells expressing Sti1 defective in Hsp7

147 and the Hsp90 inhibitor radicicol abolished curing, implying that Sti1 acts in curing through Hsp70

148 of Hsp104p on both prion induction and prion curing in a prion-specific manner.

149 This latent reservoir is a major barrier to curing individuals of HIV-1 infection.

150 Additionally, extra curing induced protruding or stepped sidewalls under hig

151 ch they contribute to reservoirs relevant to curing infection.

152 re under way to develop therapies capable of curing infection.

153 ovirus and rotavirus, in both preventing and curing infection.

154 Curing infections increasingly requires antimicrobials t

155 Hsp104 deficiency curing is a result of failure to cleave the Sup35p amylo

156 This curing is enhanced in the presence of [PIN(+)].

157 This normal-level Hsp104 curing is promoted by Sti1p, Hsp90, and Sis1p, proteins

158 Furthermore, curing is robust and not as sensitive to poisoning as ot

159 on of these prions, but its role in [PSI(+)] curing is unknown.

160 Btn2p, in curing, is colocalized with Ure2p in a single locus, sug

161 tention and symbolizes current confidence in curing it.

162 ve bioink and our understanding of thiol-ene curing kinetics with visible light, we varied the printi

163 as 8 weeks of combined antibiotic therapy in curing lesions without surgery.

164 We hypothesize that curing light transmission and cure depth are influenced

165 include the following information about the curing light: 1) radiant power output throughout the exp

166 hat has led to two new molecular methods for curing malaria.

167 in 17XNL (Py17XNL), induce a transient (self-curing) malaria infection.

168 otein 9) system, hold clinical potential for curing many monogenic disorders, including neuromuscular

169 insights into new therapeutic strategies for curing memory loss in the disease.

170 statectomy (RP) alone is often inadequate in curing men with clinically localized, high-risk prostate

171 g cause of cancer death in American men, and curing metastatic disease remains a significant challeng

172 o display to ensure high resolution of photo-curing methacrylate based SMPs that requires higher expo

173 This study indicates that using PTW as a curing method can be a potential and effective way of pr

174 es to an MV protein were highly effective at curing mice from ECTV infection when administered after

175 fficacious in an in vivo model of infection, curing mice infected with a lethal dose of S. aureus.

176 as superior to either drug alone, capable of curing mice.

177 Despite curing millions, these drug regimens are limited by the

178 erapy of choice for most patients with JMML, curing more than 50% of affected children.

179 bitors markedly improved treatment outcomes, curing more than 80% of the tumor-bearing mice.

180 g high-throughput screens, we identify prion-curing mutants and engineer "anti-prion drives" that rev

181 Antibiotics are highly effective in curing Mycobacterium ulcerans lesions, but are associate

182 The high bonding strength, the fast-curing nature, and the composition of the biobased mater

183 he computational complexity associated with 'curing' non-stoquastic Hamiltonians, i.e., transforming

184 and dynamic temperature scan DSC with light-curing occurring immediately, or at 5 or 10 minutes afte

185 ake new seeds, whereas Hsp104 overproduction curing occurs by a different mechanism.

186 phenotype that was also observed during the curing of [PSI(+)] by certain variants of [PIN(+)].

187 -21 impairment of [PSI(+)] and blocks Hsp104 curing of [PSI(+)].

188 usly implicated in the Hsp104 overproduction curing of [PSI(+)].

189 We demonstrate that both curing of [URE3] and enhancement of [PSI(+) ] in the pre

190 Our data imply that curing of [URE3] by overproduced Ydj1p does not involve

191 Cur1p is needed for Hsp42 overproduction curing of [URE3], but neither Btn2p nor Cur1p is needed

192 trated for various spectroscopic challenges: Curing of a cyanoacrylate and a two-component epoxy base

193 The photoinduced curing of a light-sensitive varnish was followed, based

194 velength (visible) irradiation, preferential curing of acrylate components is observed.

195 ected population (created through antibiotic curing of infected females) were mated to uninfected fem

196 ntilevers are fabricated by ultraviolet (UV) curing of PEG-DA prepolymer introduced into a poly(dimet

197 on-productive self-adherence, and preventing curing of the adhesive.

198 lied to investigate the edited strains after curing of the base editor plasmid.

199 s, photocrosslinkable bioinks via the direct-curing of the bioink with light through a photopermeable

200 elative to parental controls, and antibiotic curing of the gut bacteria significantly rescues hybrid

201 We experimentally characterize how the curing of the polymer affects its drainage dynamics and

202 e application of a magnetic field during the curing of the prepolymer resin.

203 Conversely, curing of the replicon from these cells results in dimin

204 can be permanently retained by templated UV-curing of the solvent, offering great promise for comple

205 ies will enable the permanent prevention and curing of type 1 diabetes.

206 the enigmatic specificity of Hsp104-mediated curing of yeast prions and sheds light on the limitation

207 known inconsistencies in the appearance and curing of yeast prions.

208 have long been known to be more effective in curing patients than single drugs, the impact of such tr

209 The only current treatment capable of curing patients with myelodysplastic syndromes (MDS) is

210 Although there are no current means of curing PD, the understanding of reactive oxygen species

211 rons alone hold the key to understanding and curing PD.

212 with different biopolymer concentrations and curing periods.

213 Curing PrD-GFP prions, by inhibiting Hsp104's fragmentat

214 idised peptides generated throughout the dry-curing process (0, 2, 3.5, 5, 6.5 and 9months), focusing

215 f the giant protein titin throughout the dry-curing process (2, 3.5, 5, 6.5, and 9 months) through th

216 sarcoplasmic proteins throughout the ham dry-curing process by using a label-free mass spectrometry m

217 old plasma (DBD-CP)-treated water as a novel curing process for manufacturing Chinese dried pork loin

218 raphene on polymer substrates using a direct curing process is demonstrated.

219 UV curable resin followed by an immediate UV curing process to polymerize the droplets and fix the or

220 . pentosus MP-10 was investigated by plasmid-curing process which showed that plasmids contribute in

221 of naturally generated peptides during a dry-curing process, showing methionine (Met) oxidation in th

222 During the curing process, those cells having both Ure2p-GFP aggreg

223 wed average pore size of 1mumwith slow (2 h) curing process.

224 peptides naturally generated during the dry-curing process.

225 sitive hydrogel during the ultraviolet light curing process.

226 t advances and remarkable improvement in the curing processes during the last decades, this disease s

227 of the oxidation mechanisms occurring in dry-curing processing.

228 resent in the samples as a result of the dry-curing production process.

229 sis enzyme, a phage integrase and a death-on-curing protein.

230 Also dry-curing proved a promising technique for masking boar tai

231 In a screen for antiprion systems curing [PSI+] without protein overproduction, we detecte

232 isible lesion," we may be one step closer to curing psoriasis.

233 bition and thereby improve the likelihood of curing RA.

234 able formulations can be analyzed during the curing reaction.

235 Btn2p curing requires cell division, and our results suggest t

236 el approaches to predicting, preventing, and curing respiratory disease.

237 n addition, a long and high-temperature film curing results is a slow and energy intensive fabricatio

238 The effects of a curing salt composition (with and without nitrifying sal

239 n nicotinamide and decrease in pyridoxine by curing salts and the decrease in both vitamins by pH24,

240 nces (TBARS) were reduced by the addition of curing salts but were low in all cases, suggesting high

241 In most cases, reduction of curing salts content resulted in significant increase of

242 The effect of the concentration of curing salts, the nature of the probiotic culture (free

243 as tools for understanding skin biology and curing skin disease outweigh potential toxicity concerns

244 ocuses on the interrelated effects of matrix curing/solidification and droplet formation.

245 in this issue demonstrate the feasibility of curing spontaneous autoimmunity in animal models via sho

246 nking was accomplished by a simple, brief UV curing step at modest temperatures.

247 rethane dimethacrylate denture resins in the curing step.

248 ich requires no further modification/ex-situ curing step.

249 ovington, and NC07-847) at harvest and after curing/storage for 4 or 8 months.

250 y almost always improves, if not permanently curing, strabismic deviations.

251 is crucial for designing the prevention and curing strategy of cancer.

252 During curing, Sup35-GFP fluorescent aggregates get bigger and

253 o advances in understanding, preventing, and curing T1D has been the inability to "see" the disease i

254 l could exist for US to enhance conventional curing techniques.

255 By varying curing temperature and resin formulation, the clear tren

256 The incorporation of Al and increased curing temperature promotes the crystallization and cros

257 h poly(4-vinyl)phenol (PVP) require very low-curing temperatures ( approximately 110 degrees C) and a

258 o satisfying interventions for preventing or curing the disease emphasize the need to better understa

259 HIV-1 reservoirs as they create barriers to curing the disease.

260 s of persistent virus infection, effectively curing the host of infection.

261 lead to novel interventions aimed at either curing the infection or preventing the development of in

262 pe 1 (HIV-1) remains a principal obstacle to curing the infection.

263 on-to-treat basis, opens the perspective for curing the large majority of these so far difficult-to-t

264 Although curing the leukemia is always the most formidable challe

265 ith a combination of F8-TNF and doxorubicin, curing the majority of treated animals (29/37).

266 sity achieved in the focal region allows for curing the material quickly, while the brief duration of

267 After curing the printed PDMS, the paper-based devices can be

268 r Treg alone or Treg-depleted CD4 T cells in curing the scurfy mice.

269 allic microwire that retains its shape after curing the silicone.

270 In vivo assays showed that curing the three plasmids resulted in severe attenuation

271 Curing the trxR mutation restored virulence comparable t

272 irus (AAV), providing a proof-of-concept for curing the vast majority of bestrophinopathies.

273 leos(t)ide analogues are capable of reliably curing the viral infection.

274 ivity of Hsp104, leading to so called "prion curing," the loss of prion-related phenotypes.

275 adhesive system is detrimental to the light-curing thereof.

276 icate the utility of chromatin remodeling in curing this complex autoimmune disorder.

277 ing new therapeutic targets and, ultimately, curing this disease.

278 There are currently no options for curing this infection.

279 abolished curing, implying that Sti1 acts in curing through Hsp70 and Hsp90 interactions.

280 ences (p > .05) in DC within each increasing curing time between the modified adhesives compared to S

281 a certain biopolymer concentration level and curing time.

282 ase of biopolymer concentration and with the curing time.

283 dium, with stiffnesses controlled by polymer curing time; (2) heart cell contractility inducible by e

284 Increasing curing times (10, 20, 40 sec) led to increased DC values

285 sors is more challenging due to their longer curing times.

286 tly subjected to a long and high temperature curing to enhance their thermoelectic properties.

287 ay include cryogenic fuel-filling, and shell curing, to produce ready-to-use IFE targets.

288 ingle-qubit orthogonal matrices, finding the curing transformation is NP-complete.

289 rstand the relationship between trimming and curing, trimming was followed by measuring the loss of G

290 s in the long-term goal of preventing and/or curing type 1 and type 2 diabetes.

291 scal investments, no means for preventing or curing type 1 diabetes exists, and, globally, the qualit

292 get that can be harnessed for preventing and curing type 2 diabetes.

293 as novel targeted therapeutic approaches for curing UC.

294 Thermal curing under reduced pressure or chemical cross-linking

295 The output from a light-curing unit (LCU) is commonly characterized by its irrad

296 nergistically increased mouse survival time, curing up to 10%.

297 led to the concept of lethal mutagenesis for curing viral infections, and work with drugs such as rib

298 the therapeutic potential of IFN-lambda for curing virus infections in the gastrointestinal tract.

299 comonomer additive in otherwise traditional curing workflows, the resulting materials can display th

300 sp104 homolog in vitro, and is essential for curing yeast prions by Hsp104 overexpression in vivo.