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1 nths; '+' refers to ongoing response at data cutoff).
2 cultured specimens (99% nucleotide identity cutoff).
3 one or more dose of patisiran up to the data cutoff.
4 n the period between first infusion and data cutoff.
5 12-month efficacy assessments as of the data cutoff.
6 .3 months (IQR 5.1-15.7) at the time of data cutoff.
7 tervals yielded 166 cm as the optimal height cutoff.
8 atient subgroups defined by the prespecified cutoffs.
9 ve predictive value for the proposed optimal cutoffs.
10 motor worsening, using clinically meaningful cutoffs.
11 s DDIR negative or positive using predefined cutoffs.
12 xplored the performance of varying LTBI test cutoffs.
13 r borderline/clinical ranges using validated cutoffs.
14 ride and/or lipase levels exceeding protocol cutoffs.
15 false discovery rate <0.05; log-fold change cutoff = 0) from 36,007 expressed Populus gene models.
18 (IE-1) antigen spot counts (SPCs) were >100 (cutoff 1) or when the IE-1 and phosphoprotein 65 antigen
20 on baseline platelet count into two groups (cutoff, 150 x 10(9) /L) demonstrated a statistically sig
21 chieved 92% sensitivity and 97% specificity (cutoff, 18 mum), whereas CPTR showed 90% sensitivity and
22 hieved 94% sensitivity and 100% specificity (cutoffs, 19 mum and 20 mum, respectively), whereas CPTR
23 SPCs were both >100 SPCs per 250 000 cells (cutoff 2), and a low CMV-CMI when SPCs were below these
26 Between Oct 26, 2015, and Nov 16, 2018 (data cutoff), 46 patients were enrolled in the dose-escalatio
31 lternative assays for hs-cTnI or hs-cTnT, no cutoff achieved the target performance: hs-cTnT concentr
32 cence in-situ hybridization in 2 age groups (cutoff age, 18 months) and were quality controlled by th
33 rformance in reference to the manufacturer's cutoff and also to a threshold chosen to achieve sensiti
36 ls, categorized according to pre-established cutoffs, and analyzed according to the severity of the d
37 on methods, technical and clinical detection cutoffs, and clinical significance of LA-DRVs in antiret
38 ts either available burden-free to the user (cutoff approach) or partially responsible for the emissi
47 dds ratio (OR) than the previously published cutoff at a MELD-Na of 20 points (vWF-Ag, OR = 10.873, 9
52 ght to identify a clinically relevant height cutoff below which waitlist mortality increases signific
57 ason score of less than or equal to 3 + 4, a cutoff could be established for detecting a Gleason scor
58 olics) > k(gingerols), resulting in multiple cutoff criteria and predicted shelf-lives (SL(predicted)
67 of June 21, 2019 (the primary analysis data cutoff date), 30 (31%; 97.5% CI 20.8-42.6) of 97 patient
68 eligibility, and as of the Jan 31, 2019 data cutoff date, 185 patients were randomly assigned to ivos
73 al quadratic regression around the 90-minute cutoff did not reveal evidence of a significant disconti
78 -based contrast administration, lowering the cutoff for administering prophylaxis to glomerular filtr
79 ers, no studies have assessed a quantitative cutoff for amyloid-beta positivity using (18)F-AZD4694 P
83 ity: 97%; specificity: 82%), and the optimal cutoff for IR diagnosis was 5.9 (sensitivity: 71%; speci
88 rdized uptake value method; the optimal TMTV cutoff for progression-free (PFS) and overall survival (
89 c analysis was used to determine the optimal cutoff for quantitative variables, and Kaplan-Meier surv
97 n using manufacturer-defined cycle threshold cutoffs for all channels was 88.7% (95% CI 83.1-94.3), a
99 on as there are no accepted quantitative PCR cutoffs for diagnosing respiratory viral infections.
100 erating-characteristic analysis to determine cutoffs for differentiation between low- and intermediat
101 ty, specificity, PPV, and NPV at the optimal cutoffs for each classifier were 94.2%, 96.9%, 97%, and
107 Using ROC-curve analysis, serum HCV-RNA cutoffs for ruling in/out any HCV+SS were established at
109 evaluated for statistical significance, and cutoffs for these parameters were determined to maximize
111 Analysis of ELISA performance at various cutoffs found that the manufacturers' recommended cutoff
112 k height in blip transients if the band-stop cutoff frequencies are compatible with the nanoparticle/
114 PEDOT:PSS hydrogels were shown to alter the cutoff frequency of the analog filter, indicating a pote
116 the vicinity of the free space ordinary mode cutoff frequency, we estimate the characteristic plasma
117 were converted dichotomously with optimized cutoffs from ROC analyses, we achieved 99.5% concordance
119 -2 (with cutoff >=2) followed by PHQ-9 (with cutoff >=10) had similar sensitivity but higher specific
120 on diagnoses, the combination of PHQ-2 (with cutoff >=2) followed by PHQ-9 (with cutoff >=10) had sim
122 for all three LTBI tests using standard U.S. cutoffs (>=5mm TST, >=0.35 IU/mL QFT, >=8 spots TSPOT).
123 ts, but its value is limited as quantitative cutoffs have only been established for a few bacterial p
124 ry tumor site, and tumor grade, the SUV(max) cutoff hazard ratio was 0.50 (range, 0.32-0.77) for PFS.
125 ts with laboratory values exceeding protocol cutoffs, implementation of the best practice advisory re
130 low-up for progression-free survival at data cutoff (July 10, 2018) was 12.4 months (IQR 8.3-21.7) in
131 were enrolled at least 26 weeks before data cutoff (June 27, 2019), and safety was assessed in all p
132 1066 participants were treated as of data cutoff (June 27, 2019), of whom 805 (76%) were evaluable
135 when compared with the conventional D-dimer cutoff level to rule out thromboembolic disease (< 500 u
136 glomerular filtration rate-adjusted D-dimer cutoff levels (> 333 ug/L [estimated glomerular filtrati
140 ics were also observed when adjusted D-dimer cutoff levels were applied in patients with acute kidney
143 ensitivity typically due to early absorption cutoff, low responsivity, and/or large dark/noise curren
144 no objective data to justify a specific age cutoff <70 years among potential SLK recipients with CKD
148 drug substance by applying molecular weight cutoff (MWCO) filtration step followed by shotgun proteo
152 l pro-B-type natriuretic peptide) alone at a cutoff of >800 identified LVSD with an area under the re
155 tead of the current high-risk classification cutoff of >=3 adenomas or any adenoma with villous growt
161 2Ae patients developing CKD stage 3 using a cutoff of 0.5 for predicting case status was better cali
163 alysis yielded an optimal (18)F-FET TBR(max) cutoff of 1.95 (sensitivity, 70%; specificity, 71%; accu
164 ent US Food and Drug Administration-required cutoff of 12.0 for designation of high-titer convalescen
167 CI, 0.85 to 0.93) to detect dementia using a cutoff of 23 or less or 24 or less (15 studies, n = 12 7
172 fication, the currently used Deauville score cutoff of an uptake above that of the liver seems to be
173 0 transcription factor genes expressing at a cutoff of FPKM >= 1 in the glandular trichomes of N. tab
175 sensitivity = 1, specificity = 0.95) using a cutoff of K(i) = 5.3 x 10(-3) mL/cm(3)/min, while k(3) a
176 s than 30 nmol/L; 34.22% (26.22-43.68) for a cutoff of less than 50 nmol/L; and 59.54% (51.32-67.50)
178 tatus was 18.46% (95% CI 10.66-27.78) with a cutoff of serum 25(OH)D concentration less than 30 nmol/
180 decreased CMV infection by PCR at viral load cutoffs of >=1000 and >=10 000 IU/mL in the CMV IVIG arm
181 ng to the frequency of visits with IOP below cutoffs of 21 mmHg, 18 mmHg, and 15 mmHg over time.
183 ucts with energy and nutrients exceeding the cutoffs of the law (i.e., products "high in") were compa
184 ts enrolled by at least 26 weeks before data cutoff, of whom 790 (75%) were evaluable for TMB and inc
194 ther HPV type restriction and more stringent cutoffs on Xpert HPV optimise performance characteristic
195 er the CD49d+ subpopulation exceeded the 30% cutoff or not, experienced clinical behavior similar to
196 prevalence, only FibroTest high specificity cutoff plus VCTE was equivalent to or better than LB.
197 patients with AF had ECV below the fibrosis cutoff point (32.8% when converted from MOLLI T1 mapping
202 tperformed different clinically relevant IgE cutoffs, predicting allergy status on an "unseen" set of
203 table mortality while avoiding arbitrary age cutoffs, premature avertable mortality from NCDs is a ro
206 ho VITROS IgG assay revealed a median signal/cutoff ratio of 24.0 for transfused units, a value far e
214 shift from above to below the 0.80 clinical cutoff, resulting into a change of the treatment strateg
215 red with reference color plots, and the SSIM cutoff score was optimized to distinguish adenosine.
218 re 0.91 (0.88-0.94) and 0.67 (0.64-0.71) for cutoff scores of 2 or greater and 0.72 (0.67-0.77) and 0
220 can be shifted to programme implementers and cutoffs selected according to resource availability and
221 ative approach for network reconstruction: a cutoff selection algorithm that maximizes the overlap of
226 opositive, the ELISA (with a 0.9 index value cutoff) showed 95.2% sensitivity, 93.4% specificity, 6.6
227 Based on the surrogate protective antibody cutoff, significantly more participants were protected a
228 the competing risk models, searching for the cutoff that gave the best model fit (as judged by the ps
230 ng samples based only on more severe symptom cutoff thresholds will likely have little impact on popu
233 for glasses 93% of the time; increasing this cutoff to >=1.50 D in both eyes increased the positive p
234 inguished quartile 3 from quartile 4 was the cutoff to distinguish medium-risk and high-risk populati
235 core for quartiles 1-2 was identified as the cutoff to identify low-risk patients; and the score that
237 2) Youden's J statistic to select optimum PS cutoffs to maximize diagnostic performance using receive
243 ered with histology to determine the optimal cutoff value for strut coverage by OCT which was defined
244 ction of mortality, assessed the appropriate cutoff value for the dichotomized score, and compared th
246 elded an optimal mean fluorescence intensity cutoff value for tumor detection of 5,775 (sensitivity o
251 a weight for length z score (WLZ) below the cutoff value of -3 SDs from the median as per the WHO 20
255 with cfDNA at 24 h concentrations above the cutoff value of healthy patients (>850 ng/ml) had a sign
256 present study was to assess the appropriate cutoff value of neointimal thickness of stent strut cove
257 ss >=40 mum by OCT yielded the most accurate cutoff value to identify stent strut coverage validated
258 racteristic analysis showed that the optimal cutoff value to predict lung tissue recruitment for the
259 mor detection, a mean fluorescence intensity cutoff value was determined from the formalin-fixed tiss
264 nfections to validate the test and determine cutoff values for use in a cascading diagnostic algorith
265 After successful internal validation of the cutoff values generated by the training cohort for DFS (
266 best predictive value for ICU mortality with cutoff values less than or equal to 1.25 arbitrary perfu
268 g the resolution of OCT is 10 to 20 mum, the cutoff values were assessed at >=20, >=40, and >=60 mum.
272 ed likelihood ratios of result intervals and cutoff values with 100% negative (NPV) and positive (PPV
274 most of the changes took place close to the cutoff values, with only few exceptions of overall left
276 acity losses in LTMOs, is independent of the cutoff voltage during delithiation and it is a reversibl
279 determined that the most effective DeltaSUV cutoff was 48.9% and that when combined with 5-PS assess
284 membrane selectivity, and the particle size cutoff was reduced from 35 to 10 nm post-treatment with
286 (p = 0.002), external validation using these cutoffs was successful for DFS (p = 0.002) but not for t
287 d 5th percentiles for SpO(2) against the WHO cutoffs, we found that the proportion of false positives
288 above the receiver operating characteristics cutoff were deceased whereas only 28% below the cutoff w
290 ensitivity and specificity of the positivity cutoffs were assessed in a clinical validation, using ur
291 food and beverage groups in which regulatory cutoffs were below the 75th percentile of the nutrient o
292 ndiseased prostate segments, and optimal SUV cutoffs were calculated using the Youden index for each
293 Three intraocular pressure (IOP) success cutoffs were defined: 18 mmHg or less and 20% reduction,
294 fs found that the manufacturers' recommended cutoffs were diagnostically specific, i.e., produced no
296 mental volume waveguide mode that exhibits a cutoff width is identified, which, interestingly, can be
297 y hybridized surface mode does not exhibit a cutoff width, and thus enables linear waveguiding of the
298 ar-HIT-IgG) and titer >=16 (ID-H/PF4-PaGIA); cutoffs with 100% NPV were <0.13 U/mL and <=1, respectiv