ライフサイエンスコーパス: cyanine

1 elevated temperatures relative to the parent cyanine.

2 hine cyanine to the corresponding trimethine cyanine.

3 ed C4'-dialkylamine-substituted heptamethine cyanines.

4 ear optical properties analogous to those of cyanines.

5 yene cations and dyes such as indigo and the cyanines.

6 per into the NIR region than common indoline-cyanines.

7 The J-aggregation of Cyanine-1dye in the presence of carboxymethyl amylose (C

8 initial donor for energy transfer with both Cyanine 3 (Cy3) and Alexa Fluor 647 (A647) fluorescent d

9 Here we report that small molecules, such as cyanine 3 (Cy3), a synthetic fluorescent molecule, and 4

10 One reporter is modified with cyanine 3 (Cy3), whereas the other is modified with a sp

11 uorescence resonance energy transfer between cyanine 3 and 5 terminally attached to duplex species ex

12 ines, were each combined with fluorescently (cyanine 3) labeled universal reference mRNA.

13 The concept was validated on cyanines 3 and 5.

14 on one side, the indole in the conventional Cyanine-3 is substituted with 3-oxo-quinoline.

15 LNPs with either hsa-let-7b-5p or cyanine 5 (Cy5)-conjugated Caenorhabditis elegans miR-39

16 L was labeled with the far-red dye sulfonate cyanine 5 (sCy5), site-specifically conjugated to the C-

17 Here, we report on a derivative of Cyanine 5 (sCy5a) that passes through the alpha-hemolysi

18 Sphingosine-cyanine 5 (Sph-Cy5) was loaded into cells, and the singl

19 Conjugation of the fluorescent probe cyanine 5 at their focal point via click chemistry permi

20 and synthesis of diverse heterobifunctional cyanine 5 dyes.

21 eavage, induced by targeted enzymes leads to Cyanine 5 signal enhancement, which is finally quantifie

22 Fluorescently (cyanine 5) labeled cDNA probes, made individually from m

23 Fluorescently (cyanine 5) labeled normal pancreas mRNA was also compare

24 Atto467N (emitting at the same wavelength as cyanine 5, Cy5) were found to bleach significantly less

25 tinct acceptor fluorophores, fluorescein and cyanine 5, to label of NCoR and SRC3, respectively, we h

26 sures intensity of marker expression using a cyanine 5-conjugated antibody within the mask.

27 aqueous solutions by the use of a mixture of Cyanine 5.5 (Cy5.5) fluorophore- and BHQ3 quencher-conju

28 Using cyanine 5.5-superparamagnetic iron oxide nanoparticle (C

29 s labeled with the fluorophore/quencher pair Cyanine 5/BHQ2.

30 tation wavelength and emission wavelength of Cyanines 5 (Cy5), was used to amplify the fluorescence s

31 Methods: A tracer comprising a methylated cyanine-5 (Cy5) fluorescent dye and a mercaptoacetyltris

32 al resonance at the excitation wavelength of cyanine-5 (Cy5), thus providing an increase in fluoresce

33 As such, simultaneous use of cyanine-5 and indocyanine green in the same patient prov

34 The cyanine-5 containing probe 25 allowed for sensitive dete

35 nts scheduled for surgical resection using a cyanine-5 fluorescence camera.

36 , ligands were successfully "clicked" with a cyanine-5 fluorophore containing the complementary "clic

37 ed that the probe incorporating a sulfonated cyanine-5 fluorophore was the most appropriate for imagi

38 robe was synthesized by covalently attaching cyanine 7 (Cy7), a near-infrared cyanine dye, to tilmano

39 -99m ((99m)Tc)-labeled TCP-1 and fluorescent cyanine-7 (Cy7)-labeled form of the peptide (Cy7-TCP-1).

40 A small subset of heptamethine dyes (cyanine-7 or Cy7) share an intriguing characteristic: pr

41 overlap of the PPESO3 fluorescence with the cyanines' absorption.

42 tes 1a-1c consisting of a BODIPY donor and a cyanine acceptor were prepared using a simple synthetic

43 that the photoconversion product is a thiol-cyanine adduct in which covalent attachment of the thiol

44 No cyanine aggregation was observed in organic solvents or

45 Two novel fluorescent cyanine-AMP conjugates, F550/570 and F650/670, have been

46 arly all organic fluorophores, including the cyanine and Alexa dyes.

47 the fluorescence and FRET behaviors of both cyanine and Alexa fluorophores.

48 c structures consist of a positively charged cyanine and negatively charged dienolate moieties, confi

49 Indolizine donor-based cyanine and squaraine dyes with water-solubilizing sulfo

50 h, we demonstrate the correspondence between cyanines and the new class of alkyne carbocations, in sp

51 The preparation of cyanine antibody conjugates, drug cleavage mediated by 6

52 the fluorescence lifetime of the restrained cyanine are not extended relative to the parent cyanine,

53 Supra-cyanines are obtained by incorporating cyanine moieties

54 However, many cyanines are prone to rapid photobleaching when irradiat

55 In contrast to studies where cyanines are utilized as photocages, our approach does n

56 sitized to target-specific activation by the cyanine-based biarsenical compounds AsCy3 and AsCy5.

57 stain SYBR Safe indicates that it contains a cyanine-based cationic core structure identical to thiaz

58 Two-photon photoconversion of cyanine-based dyes offer several advantages over existin

59 pramolecular strategy to develop ultrabright cyanine-based fluorescent materials by addressing long-s

60 nter cells upon coincubation and contain two cyanine-based fluorescent reporters covalently bound to

61 The developed anionic cyanine-based plasma membrane probes constitute an impor

62 rall, this paper reports readily accessible, cyanine-based through-bond ET cassettes that are lypophi

63 Herein, we present an array of five anionic cyanine-based turn-on plasma membrane probes with emissi

64 We report that cyanine-based, organic dyes can be efficiently photoconv

65 hetic route to pentamethine and heptamethine cyanines bearing C1' chain substituents that allow subst

66 Absorption spectra of cyanine((+)).Br((-)) salts show a remarkable solvent dep

67 the six indolizine-cyanine dyes with varying cyanine bridge length and indolizine substituents showin

68 novel donor group, indolizine, with varying cyanine bridge lengths, dye absorptions and emissions, w

69 Anionic and cationic cyanines can be organized into complementary cyanine sal

70 The implementation of [cyanine(+)] [carborane(-)] salts dramatically enhance ca

71 Here, we report the discovery of cyanine-carborane salts as potent photosensitizers (PSs)

72 methane, phenazinium and near-infrared (NIR) cyanine cationic dyes, respectively.

73 ATh(2)Btz also displays cyanine characteristics, enhancing its response upon bin

74 ormationally restraining ring systems to the cyanine chromophore creates exceptionally bright fluorop

75 The overall process couples a cyanine chromophore with a urea bridge giving rise to ne

76 ning substituent effects on the heptamethine cyanine chromophore, we find that introduction of a sing

77 A cyanine-class near-infrared fluorescent dye, Cy7, and do

78 ically examine the self-healing mechanism in cyanine-class organic fluorophores spanning the visible

79 Our previous work found trimethine cyanine compounds that effectively inhibit PRMT1 activit

80 isualized with fluorescence microscopy using cyanine-conjugated and fluorescein-conjugated secondary

81 visualized by fluorescence microscopy using cyanine-conjugated and fluorescein-conjugated secondary

82 arise from the cationic nature of the target cyanine-containing sensitizers (S), which drastically li

83 NIR-nanogels feature a photolabile cyanine cross-linker (Cy780-Acryl) that can cleave via d

84 Hybridization signals were visualized with cyanine (Cy)-5 or Cy-3 fluorescent reporter molecules, a

85 dyes (termed dyedrons) comprised of multiple cyanine (Cy3) donors coupled to a single malachite green

86 Cyanines (Cy3, Cy5, Cy3B) are the most utilized dyes for

87 ctly to the pentamethine chain of a deep-red cyanine (Cy5) energy acceptor.

88 Heptamethine cyanines (Cy7) are fluorophores essential for modern bio

89 estigation of the truncation of heptamethine cyanines (Cy7) to pentamethine (Cy5) and trimethine (Cy3

90 tophysics and photochemistry of heptamethine cyanines (Cy7), bearing iodine as a heavy atom in the C3

91 New red-shifted emission at 615 nm from cyanine-cyanine dimers and DFT calculations agree with K

92 o significantly reduce the strong and random cyanine-cyanine interactions (i.e., aggregation) in the

93 t labeling of lysine groups on proteins with cyanine CyDye DIGE Fluor minimal dyes before isoelectric

94 idic media with the generation of a deep red cyanine derivative, absorbing at 537 nm, which is visibl

95 esses that can occur during the synthesis of cyanine derivatives.

96 erful tool for accessing a new generation of cyanine derivatives.

97 SYBR Green 1 is an asymmetrical cyanine DNA-binding dye that provides an opportunity for

98 orts, the photoisomerization of heptamethine cyanines does not contribute significantly to the excite

99 experiments compared a shielded heptamethine cyanine dye (and several peptide and antibody bioconjuga

100 esting nanotubes derived from an amphiphilic cyanine dye (C8S3-Cl).

101 n allowed the conjugation with a fluorescent cyanine dye (Cy5) and biotin, resulting in binding K(i)

102 and MeHg(+) -responsive near-infrared (NIR) cyanine dye (hCy7) for MeHg(+) detection within living s

103 -rotaxane supramolecular assembly with a Cy7 cyanine dye (hexamethylindotricarbocyanine) threaded alo

104 all the dyes studied relative to a benchmark cyanine dye (ICG) during photoexcitation with exceptiona

105 Herein we utilize cyanine dye 3,3'-diethyl-9-methyl-thiacarbocyanine iodid

106 tact and were detected using the symmetrical cyanine dye 3,3'-diethylthiadicarbocyanine iodide (DiSC2

107 engineering strategies designed to red-shift cyanine dye absorptions and emissions further into the n

108 ansferred through an acetylene bridge to the cyanine dye acceptor, which emits light at approximately

109 tion of densely packed, discrete clusters of cyanine dye aggregates with tunable absorption spectra a

110 tilized coupling between a tetrazine-derived cyanine dye and a trans-cyclooctene-modified bisphosphon

111 Pyrvinium is a quinoline-derived cyanine dye and an approved anti-helminthic drug reporte

112 ormation of an encounter complex between the cyanine dye and ionized thiol prior to their conjugation

113 to study the interaction between a cationic cyanine dye and peptide nucleic acid (PNA)-DNA duplexes.

114 enching of a conjugated polyelectrolyte by a cyanine dye are investigated by femtosecond fluorescence

115 his is the first demonstration of an encoded cyanine dye as a ncAA in a eukaryotic expression system

116 at combines a rhodium metalloinsertor with a cyanine dye as the fluorescent reporter.

117 ble-walled nanotubes (DWNTs) formed from the cyanine dye C8S3 provide a robust, self-assembled system

118 Overall, a cyanine dye can dissociate aggregated Tau in an ex vivo

119 Five new cyanine dye cassettes were created by covalently attachi

120 Solution and solid-phase syntheses of a cyanine dye conjugated to polystyrene beads (desired for

121 The cyanine dye Cy3 is a popular fluorophore used to probe t

122 or, for popular alkyl-thiols, are limited to cyanine dye Cy3 protection.

123 We report that the cyanine dye Cy5 and several of its structural relatives

124 BLM, deglycoBLM, and BLM disaccharide to the cyanine dye Cy5**.

125 assay, and in vivo optical imaging using the cyanine dye Cy5.5 conjugate.

126 blueing" reaction, in which the heptamethine cyanine dye Cy7 (IUPAC: 1,3,3-trimethyl-2-((1E,3E,5E)-7-

127 probe (TRAP) consisting of a monosubstituted cyanine dye derivatized with arsenic (i.e., TRAP_Cy3) to

128 layed library for binding to the fluorogenic cyanine dye Dimethyl Indole Red (DIR).

129 We have used a cyanine dye family as a paradigm and high-resolution cap

130 ry oligonucleotides were conjugated with the cyanine dye fluorophores Cy3 and Cy5 to quantify the mel

131 utility of the fluorous soluble pentamethine cyanine dye for tracking the localization of perfluoroca

132 A new asymmetric, squarylium cyanine dye functionalized by boronic acid ("SQ-BA") was

133 d the photophysics of the series and monomer cyanine dye have been studied in solution.

134 ons from PbS QDs by adsorbed J-aggregates of cyanine dye in aqueous dispersions.

135 is observed from J-aggregates of the achiral cyanine dye in association with a random coil CMA, sugge

136 The benzothiazole cyanine dye K21 forms dye aggregates on double-stranded

137 Although cyanine dye loading is often accompanied by fluorescence

138 estigated for polyelectrolytes consisting of cyanine dye pendant polylysines ranging in number of pol

139 The influence of the DNA target and probe cyanine dye position on oligo-DNA duplex formation behav

140 water solubility by modifying rhodamine and cyanine dye scaffolds with multiple sulfonate groups.

141 we have introduced the bis-quinoline (BisQ) cyanine dye that emits light in the red region (605-610

142 YTOX Green stain is a cationic unsymmetrical cyanine dye that is excluded from live cells but can rea

143 We have developed a new unsymmetrical cyanine dye that overcomes this problem.

144 The cyanine dye thiazole orange (TO) is a well-known fluorog

145 s efficient energy transfer from the central cyanine dye to the surrounding zinc porphyrin nanoring.

146 A symmetrical cyanine dye was previously shown to bind as a cofacial d

147 Therefore, the heptamethine cyanine dye will be an attractive scaffold to create a s

148 sensor 790 combines a near-infrared emitting cyanine dye with a sulfur-rich receptor to provide a sel

149 on between DNA and a benzothiazole-quinoline cyanine dye with a trimethine bridge (TO-PRO-3) results

150 labeling method using ISEL combined with the cyanine dye YOYO-1 that binds to DNA.

151 erated photobleaching of the light-sensitive cyanine dye, 3,3'-diethylthiacarbocyanine iodide (DiSC(2

152 re examined: Rhodamine 6G, crystal violet, a cyanine dye, and a cationic donor-acceptor substituted s

153 lipid-specific since inclusion of a cationic cyanine dye, DiIC18(3), to impart positive charge in pla

154 amer selected for binding to the fluorogenic cyanine dye, dimethylindole red (DIR), also binds and ac

155 irect the formation of dye aggregates with a cyanine dye, K21, into discrete branched photonic comple

156 y attaching cyanine 7 (Cy7), a near-infrared cyanine dye, to tilmanocept, a radiopharmaceutical that

157 a rational approach to develop colorimetric cyanine dye-displacement assays that can be broadly appl

158 Receptor-bound, cyanine dye-labeled ligands, [Cy]ligands, were discrimin

159 d to adjust the extent of aggregation of the cyanine dye.

160 model the trans-cis isomerization of a model cyanine dye.

161 plays an induction period unlike that of the cyanine dye.

162 s conjugated to Cy5.5, a near-infrared (NIR) cyanine dye.

163 um, including a near-infrared (NIR)-emitting cyanine dye.

164 ine kinase c-Met conjugated to a fluorescent cyanine dye.

165 d with increasing DS (of CMA), rendering the cyanine dye/CMA complex a more rigid (a high fluorescenc

166 ans of Stark effect in planar heterojunction cyanine dye/fullerene organic solar cells enables one to

167 Here, we show that, when cyanine-dye labeled 2'-deoxy and 2'-O-methyl oligonucleo

168 's complexity: cylinders self-assembled from cyanine-dye molecules.

169 Similar cyanine dyes (DiSC(3)(3), DiSC(4)(3), DiSC(5)(3), and Di

170 Other cyanine dyes (e.g., Cy3, Alexa 555) were not significant

171 data that show susceptibility of a class of cyanine dyes (e.g., Cy5, Alexa 647) to ozone levels as l

172 Among those heptamethine cyanine dyes analyzed, 13 compounds within the nontoxic

173 e-shell nanoparticles that encapsulated with cyanine dyes and applied the dye-doped nanoparticles as

174 Cyanine dyes are a class of organic, usually cationic mo

175 Cyanine dyes are exceptionally useful probes for a range

176 Polymethine cyanine dyes are fascinating molecular wires because up

177 ocavities containing two spatially separated cyanine dyes are presented here, where simultaneous stro

178 Cyanine dyes are widely used fluorophores with a range o

179 Cyanine dyes are widely used in bioimaging, sensing, opt

180 Unsymmetrical cyanine dyes are widely used in biomolecular detection d

181 ntum dot-quantum rods (QD-QRs) as donors and cyanine dyes as acceptors, which are conjugated to QD-QR

182 terature survey indicated no previous use of cyanine dyes as contrast agents for in vivo optical dete

183 ed for the site-specific genetic encoding of cyanine dyes as non-canonical amino acids (Cy-ncAAs) int

184 Previous studies have utilized cyanine dyes as Tau aggregation inhibitors in vitro.

185 -to-high-yielding synthesis of unsymmetrical cyanine dyes bearing -COOH substituents for functionaliz

186 phile that initiates chain shortening of the cyanine dyes by attack on their polymethine backbones.

187 , monofunctional, water-soluble heptamethine cyanine dyes containing a robust C-C bond at the central

188 dure to the synthesis of otherwise difficult cyanine dyes containing multiple heteroatoms in the indo

189 Heptamethine cyanine dyes enable deep tissue fluorescence imaging in

190 evelop near-infrared fluorescent polymethine cyanine dyes for biological imaging and sensing.

191 -infrared window of fluorescent heptamethine cyanine dyes greatly facilitates biological imaging beca

192 Cyanine dyes have been shown to undergo reversible photo

193 Polymethine cyanine dyes have been widely recognized as promising ch

194 l trimethine, pentamethine, and heptamethine cyanine dyes in near-quantitative yields.

195 nding of structure-property relationships in cyanine dyes is critical for their design and applicatio

196 oping structure-aggregation relationships of cyanine dyes is crucial for controlling their optical pr

197 Polymethine bridges in cyanine dyes may be constrained by setting them into edg

198 spectral properties of a series of dianionic cyanine dyes of the rare A(1)-n-A-n-A(1) type, with the

199 ese studies demonstrate that the red-shifted cyanine dyes offer spectral flexibility in multiplexed i

200 Cyanine dyes play an indispensable and central role in m

201 Here, we introduce fluorous cyanine dyes that represent the most red-shifted fluorou

202 the corresponding electronic potential makes cyanine dyes the compounds to which simple free-electron

203 le fragment antibody protein and a family of cyanine dyes to create new protein-dye fluoromodules tha

204 beling methodology that uses platinum-linked cyanine dyes to directly chemically label mRNA from as l

205 nsfers the pH sensitivity of photolabile NIR cyanine dyes to highly emissive and long-lifetime pH-ins

206 the direct transformation of Zincke salts to cyanine dyes under mild conditions, accompanied by the i

207 amplified quenching of PPESO3 by a series of cyanine dyes via singlet-singlet energy transfer.

208 phenyl-, and phenyl-substituted heptamethine cyanine dyes were prepared by a modified Suzuki--Miyaura

209 is study, four novel pentamethine indolizine cyanine dyes were synthesized with N,N-dimethylaniline-b

210 h high affinity to several other fluorogenic cyanine dyes with emission wavelengths covering most of

211 In recent work to develop cyanine dyes with especially large Stokes shifts, we enc

212 In water, cyanine dyes with extended conjugation are known to cros

213 ssisted synthesis of asymmetric pentamethine cyanine dyes with various functional groups was develope

214 ionships are explored for the six indolizine-cyanine dyes with varying cyanine bridge length and indo

215 lass of NIR fluorescent dyes, pyrrolopyrrole cyanine dyes, have exceptionally long FLTs ranging from

216 spectroscopy, and DFT modeling on a range of cyanine dyes, herein we show that photoinduced electron

217 el doubly strapped zwitterionic heptamethine cyanine dyes, including a structural analogue of ZW800-1

218 ing long-standing challenges associated with cyanine dyes, including undesired cis-trans photoisomeri

219 The binding interactions between two cyanine dyes, pseudoisocyanine (PIC) and pinacyanol (PIN

220 were obtained for host-guest films using two cyanine dyes, reaching 27%.

221 g is first visualized through conjugation of cyanine dyes, then biological utility is highlighted by

222 and higher emission rates than commonly used cyanine dyes.

223 d by PCR, and the products were labeled with cyanine dyes.

224 ic ligands, were prepared using red-emitting cyanine dyes.

225 -helix DNA-binding motifs with intercalating cyanine dyes.

226 PAINT) based on fluorogenic dimers of bright cyanine dyes.

227 The favorable properties of cyanines (e.g., near-infrared (NIR) absorbance and emiss

228 ted heavy atom effect operating in the close cyanine/Er pair.

229 nine are not extended relative to the parent cyanine, even in viscous solvents.

230 l as one may think; rhodamines belong to the cyanine family whereas rhodols belong to merocyanines.

231 DNA constructs labeled with cyanine fluorescent dyes are important substrates for si

232 les are formed from a commercially available cyanine fluoroalkylphosphate (CyFaP) salt dye and used f

233 4-nitrobenzyl alcohol (NBA) or Trolox to the cyanine fluorophore Cy5 dramatically enhanced fluorophor

234 mbrane antigen (PSMA); 2) a NIR heptamethine cyanine fluorophore optimized for enhanced PSMA binding

235 ly unexploited photochemical reaction of the cyanine fluorophore scaffold.

236 ed as ca. 20 pM (equivalent to 10 zmol) of a cyanine fluorophore, Cy5.

237 Cyanine fluorophores are commonly used in single-molecul

238 Far-red cyanine fluorophores find extensive use in modern micros

239 nal stacking is an intrinsic property of the cyanine fluorophores irrespective of the length of the t

240 port the synthetic variation of pentamethine cyanine fluorophores with modifications of physicochemic

241 nd through meso-substitution of pentamethine cyanine fluorophores.

242 ally over the fluorochromes of near-infrared cyanine heptamethine dyes to create hydrophilic analogs

243 Antagonist activity depended on cyanine heterocycle, polymethine bridge length, and the

244 ucture-activity relationship for symmetrical cyanine inhibitors of human tau aggregation was elaborat

245 HF6/PH6* hexapeptide motifs, indicating that cyanine interacted with a species in the aggregation pat

246 ion of the favorable molecular properties of cyanines into macroscopic material properties.

247 yanine Cy7 or, alternatively, a heptamethine cyanine IRDye 800CW) that were linked at the positions +

248 ence lifetime of the restrained heptamethine cyanine is temperature-insensitive and significantly ext

249 s via Forster resonance energy transfer from cyanine J-aggregates.

250 By titrating DB270 and/or cyanine-labeled DNA with protein or unlabeled DNA, and f

251 yridine derivatives IIIa and IVa displayed a cyanine-like character with intense absorption and highe

252 he very small reorganization energy in these cyanine-like chromophores.

253 of the third-order polarizability (gamma) of cyanine-like molecules through incorporation of polariza

254 amer, display conjugated structures near the cyanine limit of bond length equalization as a result of

255 ded conjugation are known to cross over the "cyanine limit" and undergo a symmetry breaking Peierls t

256 t chemistry can be employed to mitigate the "cyanine limit" problem.

257 Supra-cyanines are obtained by incorporating cyanine moieties in a cyclic peptide-based supramolecula

258 itting electrochemical cells (LECs) based on cyanine molecules were prepared.

259 red (DIR), also binds and activates another cyanine, oxazole thiazole blue (OTB), giving two well-re

260 on the nature of the dye pair used, with the cyanine pair Cy3-Cy5 showing the least amount of fluctua

261 -dioctadecyl-3,3,3',3'-tetra-methylindocarbo-cyanine perchlorate (DiI) was applied via tracheal insti

262 '-dioctadecyl-3,3,3',3'-tetramethylindocarbo-cyanine perchlorate (DiI) was used to label selectively

263 dioctadecyl-3,3,3',3'-tetramethylindodicarbo-cyanine perchlorate.

264 elating the ground state polarizabilities of cyanine, phenothiazine, and arylmethine derivatives calc

265 Here, we report synthetically accessible cyanine photocages that liberate alcohol, phenol, amine,

266 divergent results and enabling control over cyanine photoreactivity is however missing.

267 vide critical insight into the reactivity of cyanine polyene chains and elucidate the truncation mech

268 resonance energy transfer (FRET), and loaded cyanine probe (e.g., 1,1-dioctadecyl-3,3,3,3-tetramethyl

269 g mice by two-photon microscopy, the anionic cyanine probes allowed us to visualize in detail the pyr

270 absorption and emission with squaraines and cyanines relative to classically researched indoline don

271 lors by covalently linking a photoswitchable cyanine reporter and an activator molecule to assist bio

272 cyanines can be organized into complementary cyanine salts, offering potential building blocks to mod

273 le of photoisomerization in the heptamethine cyanine scaffold and demonstrate the dramatic effect of

274 of covalently appended fluorous tags on the cyanine scaffold and evaluate the changes in photophysic

275 fluorogenic probes based on the heptamethine cyanine scaffold, the most broadly used NIR chromophore.

276 t on atomic and orbital structure across the cyanine series.

277 Measurement of the time dependence of cyanine staining of pores shows fluctuations of fluoresc

278 Scaffolds that favor the cyanine state (i.e., narrow, red-shifted absorption and

279 nlike conventional scaffolds, they favor the cyanine state with increasing solvent viscosity and hydr

280 PF555 is an asymmetric cyanine structure in which, on one side, the indole in t

281 gated the structure-activity relationship of cyanine structures.

282 Further, as is the case with many cyanines, the dye suffers from low photostability.

283 tion that converts the simplest heptamethine cyanine to the corresponding trimethine cyanine.

284 rm complexes with highly polarizable anionic cyanines to significantly reduce the strong and random c

285 modified by (a) electronic tuning along the cyanine-type axis via modification of the donor-acceptor

286 etermined by the electronic structure of the cyanine-type backbone (approach (a)).

287 In these probes, the two cyanine units connected with a linker were modified at t

288 These modalities exploit cyanines' versatile photochemical behavior with thiols.

289 ) to pentamethine (Cy5) and trimethine (Cy3) cyanines via homogeneous, acid-base-catalyzed nucleophil

290 ng radical prostatectomy using near-infrared cyanine voltage-sensitive dye (VSD) imaging, which visua

291 issense mutants as targets, interaction with cyanine was localized to the microtubule binding repeat

292 The photophysical behavior of the cyanines was investigated using UV-vis and steady-state

293 New cyanines were prepared by an efficient and practical rou

294 se (tens of cm(-1) for the chain-substituted cyanines), which allowed us to interpret the observed po

295 Cyanines, which represent a class of charged chromophore

296 elies on the methine extension of asymmetric cyanines, which unfortunately fails to produce sensitive

297 are based on rhodamines, carbopyronines and cyanines with excellent photophysical properties, that i

298 single anions leading to isolation of single cyanines with monomer emission at 507 nm.

299 of which will accelerate the development of cyanines with properties tailored for specific applicati

300 t harness the near-infrared (NIR) absorbing [cyanine(+)] with the inertness of [carborane(-)].