ライフサイエンスコーパス: cycle

1 long-with ATRA (45 mg/m(2) orally, days 1-15/cycle).

2 a-stable cycling stability (96.6% after 5000 cycles).

3 Maintenance venetoclax was permitted (7 cycles).

4 h cm(-2) ), and long cycle life (over 10 000 cycles).

5 entage of GSCs in M- and S-phase of the cell cycle.

6 ing in the mHsp60-mHsp10 chaperonin reaction cycle.

7 essory factors helps order the transcription cycle.

8 HPV-mediated carcinogenesis and the HPV life cycle.

9 its multifunctional role during the AAV life cycle.

10 zymatic step of the tricarboxylic acid (TCA) cycle.

11 t the expense of transfer to the methylation cycle.

12 ic mechanism of the eukaryotic cell division cycle.

13 ranscription, DNA damage repair and the cell cycle.

14 following the galvanostatic charge-discharge cycle.

15 g a model for the biological water oxidation cycle.

16 tabolic network, was used to close the first cycle.

17 ple lipid substrates may be transported each cycle.

18 two electron transfers within the catalytic cycle.

19 is a critical parameter in the ocean carbon cycle.

20 a coordinated and directional GTP-hydrolysis cycle.

21 for multiple phases of the viral replication cycle.

22 uture investigations of the global marine Si cycle.

23 of the pressure waveform during the cardiac cycle.

24 anges in axial strain throughout the pumping cycle.

25 ructure of PfMyoA in two states of its motor cycle.

26 tty acids all contributed carbons to the TCA cycle.

27 tes rhythmic expression across the day/night cycle.

28 key replication events during the HIV-1 life cycle.

29 ntermediates in the canonical polymerization cycle.

30 ial version of this model across a circadian cycle.

31 symmetry and differentiation during the cell cycle.

32 that play a major role in the global carbon cycle.

33 context of the entire nairovirus replication cycle.

34 scuss implications on the terrestrial carbon cycle.

35 5 intermediate states in the water-splitting cycle.

36 er several consecutive adsorption/desorption cycles.

37 erage Coulombic efficiency of 99.1 % for 350 cycles.

38 levels of redox ratios in synchrony with the cycles.

39 nd time between two consecutive chemotherapy cycles.

40 intravenously once every 3 weeks, in 3-week cycles.

41 te to bridge sylvatic and human transmission cycles.

42 ts initial enzymatic activity after 15 reuse cycles.

43 eceptor CXCR2 and by regulators of circadian cycles.

44 sign of degradation after ~10(10) switching cycles.

45 ) with capacity retention of 97.6% over 2000 cycles.

46 reased further after additional blinatumomab cycles.

47 int was met, with an sCR rate of 60% after 8 cycles.

48 ity following multiple adsorption-desorption cycles.

49 ) cathodes to achieve 101.6 mAh g(-1) for 50 cycles.

50 affecting the step length over multiple gait cycles.

51 close linkage between soil microbial C and N cycling.

52 ant consequences for biogeochemical nitrogen cycling.

53 associated with decoupling of litter C and N cycling.

54 es were driven by both N speciation and diel cycling.

55 lly important consequences for global carbon cycling.

56 the symbiotic lifestyle and aids in nutrient cycling.

57 ule of 4 days on and 3 days off (starting on cycle 1 day 15) until disease progression, unacceptable

58 ry 28 days (plus a loading dose on day 15 of cycle 1) with either capivasertib 400 mg or matching pla

59 Two cycles of therapy were offered (cycle 1: CPX-351; cycle 2: FLAG [fludarabine 30 mg/m(2)/

60 ng Cancer 13 (QLQ-LC13) were administered at cycles 1-5, every three cycles thereafter during year 1,

61 from host evolution to global biogeochemical cycles(1,2).

62 s of therapy were offered (cycle 1: CPX-351; cycle 2: FLAG [fludarabine 30 mg/m(2)/dose on days 1-5;

63 Perfusion increased from cycle 4 to disease progression (51% +/- 11; P < .001).

64 Rac family small GTPase 1 and cell division cycle 42 activation, as well as downstream intracellular

65 Conversion over time data is obtained by cycling a discrete reaction slug back and forth between

66 from lipogenesis toward ketogenesis and TCA cycle, a milieu which can hasten oxidative stress and in

67 er and monomer photoreception, dimer/monomer cycling, abundance of native COP1 and RUP proteins, and

68 e of ATP hydrolysis and blocks the catalytic cycle after formation of the aspartyl phosphate intermed

69 cycles until disease progression or up to 6 cycles after complete hematologic response.

70 hol binding models with thermodynamic mutant cycle analysis.

71 ociated with plasticity/rigidity of the cell cycle and correlated with sensitivity to CDK4/6 inhibiti

72 le of E2F2 in cancer progression beyond cell cycle and could impact patient treatment.

73 We focus on the cell cycle and describe its dependence on pre-mRNA splicing a

74 LuxS is essential for the activated methyl cycle and generates homocysteine for conversion to l-met

75 nce in coordination with the DNA replication cycle and have an important role in segregating genetic

76 s revealed downregulation of matrisome, cell cycle and immune related gene sets in Lcn2(-/-) mice exp

77 To elucidate their catalytic cycle and inhibitory mechanism, we report 11 x-ray cryst

78 ipheral homeostasis in the CD4+ Th cell life cycle and invariant NK (iNK) T cell development and CD8+

79 OX blocks apicoplast biogenesis in the first cycle and is rescued by isopentenyl pyrophosphate, an es

80 ranscriptase (TERT) throughout its catalytic cycle and mapped the active site residues responsible fo

81 including impairments of the gamma-glutamyl cycle and methylglyoxal detoxification.

82 and transporter genes, ascorbate-glutathione cycle and nutrient uptake, and lowering in oxidative str

83 line metabolism by up-regulating the proline cycle and proline biosynthesis, and knockdowns of PYCR1

84 h and counteracted EZH2 and SOX2 during cell-cycle and self-renewal regulation to restrain tumorigene

85 over have direct impacts on the hydrological cycle and stream quality.

86 cycle continuum to within 14% of the entire cycle and that using more genes did not improve this acc

87 product (RAP) were obtained for each cardiac cycle and their dynamic response to a step change in MAP

88 t 25 and 250 mug/kg BW/d altered the estrous cycle and uterine pathology with similarity to EE2.

89 therapy, with a reciprocal decrease in cell-cycle and WNT signaling pathways in responding biopsies.

90 wing no significant activity loss after 5000 cycles and 25 h of operation in acid.

91 s given in 21-day cycles for the first eight cycles and 35-day cycles from the ninth cycle until dise

92 ries from a Kansas prairie revealed both 5-y cycles and declines of 2.1-2.7%/y.

93 column potentially influence biogeochemical cycles and the pelagic food web structure.

94 ationship between the number of chemotherapy cycles and time between two consecutive chemotherapy cyc

95 y to distant habitats and for inshore carbon cycling and (potentially) carbon sequestration.

96 methane production drives a cryptic methane cycling and fuels AOM coupled to the reduction of sulfat

97 e are an essential link in soil nitrogen (N) cycling and plant N supply.

98 ion plays an important role in terrestrial N cycling and represents a key driver of terrestrial net p

99 every 3 weeks (8 mg/kg loading dose at first cycle, and 6 mg/kg thereafter) for 18 doses or weekly (4

100 luconeogenesis, the tricarboxylic acid (TCA) cycle, and amino acid synthesis/catabolism.

101 Given their catadromous life-cycle, and global commercial and cultural importance, as

102 localize to centrosomes throughout the cell cycle, and in interphase cells to the nucleus, and in bo

103 ysis/gluconeogenesis, the tricarboxylic acid cycle, and monosaccharide and disaccharide metabolism.

104 Changes in the geological sulfur cycle are inferred from the sulfur isotopic composition

105 r this and other microalgal species, diurnal cycles are well known to control the metabolism, growth,

106 ominant mechanisms that determine the carbon cycling are different between the consolidated gully and

107 Y cells with PMA and it correlated with cell cycle arrest at G2/M, upregulation of tumor suppressor p

108 nd that overexpression of ABHD5 induces cell cycle arrest at the G1 phase and causes growth retardati

109 hysiologically, DJ34 induced apoptosis, cell cycle arrest, and cell differentiation.

110 s in different cell-cycle phases and in cell-cycle arrest.

111 by transient Snt1 phosphorylation upon cell cycle arrest.

112 ak and trough that correlates with a cardiac cycle as revealed by a reference pulse oximeter (correla

113 very low average voltage decay of 0.8 mV per cycle as well as a capacity retention of 88.4% within 20

114 s able to facilitate wood decay and nutrient cycling as well as tolerate latex and utilize resinous e

115 In the second cycle, AS microbiome was enriched toward caproate produc

116 increasingly predictable over multiple fire cycles, as boundaries are progressively sharpened until

117 Seventy-one unique life cycle assessment (LCA) studies that quantify the environ

118 n retention of 1-carbon groups in the folate cycle at the expense of transfer to the methylation cycl

119 as a capacity retention of 88.4% within 200 cycles at 200 mA g(-1) .

120 (and perhaps other stages) of the viral life cycle, based on several lines of evidence.

121 is is that logging influences phosphorus (P) cycling, because this scarce nutrient is removed in extr

122 or emerges, in which the period of the limit cycles becomes an integer n > 1 multiple of the driving

123 Many bacteria cycle between sessile and motile forms in which they mus

124 re of the SAT varied with phases of the gape cycle, but gape distance accounted for the majority of d

125 Synthetic trees can mimic this transpiration cycle, but have been confined to pumping water across a

126 eota are important organisms in the nitrogen cycle, but the mechanisms driving their radiation into d

127 s on progression through S phase of the cell cycle, but the molecular nature of this requirement has

128 mproving the harvested energy per mechanical cycle, but they are complicated to implement at such vol

129 a suggest that LGR4 promotes the normal hair cycle by activating HF stem cells and by influencing the

130 sive cellular enlargement during slowed cell cycles by down-regulating translation capacity.

131 to blood pressure variability (BPV)-induced cycle-by-cycle fluctuations in mechanical forces which v

132 scopy to demonstrate that the apparent first-cycle capacity loss is a kinetic effect linked to limite

133 During late M-phase of the cell-cycle, Cdc6 binds to ORC and the ORC-Cdc6 complex loads

134 ls show that these extinction-related carbon cycle changes would have allowed the ocean to absorb mas

135 To successfully complete its life cycle, Chlamydia must evade both intracellular innate im

136 innate immunity, chronic inflammation, cell cycle, circadian rhythm, and olfactory functions.

137 scentus employs a specialized dimorphic life cycle consisting of two differentiated cell types.

138 ffects of contact force, scan speed, contact cycles, contact region and charge diffusion on the trans

139 enes predicted a cell's position on the cell cycle continuum to within 14% of the entire cycle and th

140 g tool to facilitate in vivo studies of cell-cycle control in a wide-range of developmental contexts.

141 er, we use cell cycle tags to reinstall cell cycle control to a deregulated version of Yen1, showing

142 tion of Aurora B in interphase leads to cell cycle defects often linked to aberrant chromosomal conde

143 4(-/-) mice can effectively reverse the hair cycle delay.

144 To determine whether cell-cycle-dependent gene regulation occurs in mycobacteria,

145 Cell cycle-dependent redox changes can mediate transient cova

146 ifically, we find that genes related to cell cycle, DNA repair, cell death, the IGF1 pathway, and imm

147 ange intra-generational correlations in cell-cycle duration, up to second cousins, seem paradoxical b

148 vate neural differentiation and inhibit cell cycle during the transition, whereas epilepsy genes func

149 les thereafter during year 1, and every four cycles during years 2-3.

150 d key regulatory enzymes that drive the cell cycle, elucidated structural components that underly ess

151 Mammalian cells typically start the cell-cycle entry program by activating cyclin-dependent prote

152 ors to inhibitors with size, triggering cell-cycle entry.

153 However, annual life cycle environmental impacts of crop production at county

154 change causes changes in the timing of life cycle events across all trophic groups.

155 and neurovascular coupling during submaximal cycling exercise and temperature-matched passive heat st

156 end-tidal PCO2 was held constant) Submaximal cycling exercise and temperature-matched passive heat st

157 w uncover that when the epigenetic chromatin cycle falters, a genetically hardwired mechanism offers

158 s important to predict future climate-carbon cycle feedbacks.

159 in projecting future climate and carbon (C) cycle feedbacks.

160 bore into tree xylem to complete their life cycle, feeding on symbiotic fungi.

161 four genes) and the tricarboxylic acid (TCA) cycle (five genes), and four genes (GmFATB1a, GmPDAT, Gm

162 pressure variability (BPV)-induced cycle-by-cycle fluctuations in mechanical forces which vary consi

163 lative standard deviations (RSD) between the cycles for human plasma samples were 0.84-6.6%.

164 ements of the nonphotopic or photopic visual cycles for mediating vision in bright light.

165 Treatment was given in 21-day cycles for the first eight cycles and 35-day cycles from

166 cycles for the first eight cycles and 35-day cycles from the ninth cycle until disease progression, u

167 , extracted from chest radiographs after the cycle-GAN's texture translation (fake chest radiographs)

168 limate change has intensified the hydrologic cycle globally, increasing the magnitude and frequency o

169 Models that characterize life cycle greenhouse gases from electricity generation are l

170 that significant variations existed in life cycle GWP, EU, and AD among counties and across years.

171 services such as water filtration, nutrient cycling, habitat stabilization, and food web enhancement

172 Patients with NMRs >= 5.75 after the first cycle had significantly higher objective response rates

173 Ct value for asymptomatic children was 10.3 cycles higher than for symptomatic children (P < 0.0001)

174 During the nivolumab treatment cycle, his pertinent laboratory values and physical exam

175 During the estrous cycle, however, which includes a brief, but pronounced,

176 e molecular mechanisms and logic of the cell cycle, identified key regulatory enzymes that drive the

177 There are currently limited life cycle impact assessment methods existing for assessing i

178 ing the normal physiological fasting-feeding cycle in nutrient-sensitive and -insensitive mice.

179 2l 1) caused significant effects on the cell cycle in PC3 cells, with the vast majority of treated ce

180 s, we examined key aspects of the viral life cycle in three-dimensional (3-D) human airway tissues.

181 consistent decrease in the C. difficile life cycle in vivo, it was able to attenuate an overly robust

182 etermine rate constants of the AGO2 cleavage cycle in vivo.

183 s is driven by molecular clock timing, which cycles in anti-phase between day- versus night-biting mo

184 r reduction in NPM1mut TLs after 2 treatment cycles in MRD positive patients by the addition of GO le

185 out how reactive Fe and Al minerals affect C cycling in restored wetlands.

186 evidence of EM fungal suppression of C and N cycling in the Pinus-dominated site, but no suppression

187 Each surface loop was evolved by infectious cycling in the presence of a helper adenovirus to yield

188 d by major U speciation changes due to redox cycling in the wetland.

189 onal repressor of key regulators of the cell cycle, in turn influencing contact inhibition and tumori

190 inate receptor 1 or GPR91) senses the citric cycle intermediate succinate and is implicated in variou

191 cally reduced intracellular succinate, a TCA cycle intermediate that serves as a direct electron dono

192 atalyst, which introduces a second catalytic cycle into the metabolic network, was used to close the

193 The chromosome breakage-fusion-bridge (BFB) cycle is a mutational process that produces gene amplifi

194 ediate steps are minimized and the catalytic cycle is devoid of high transition-state barriers.

195 function of this mark within the infectious cycle is unknown.

196 rinciple QTL determining SET (SET1: dormancy cycling) is physically close on chromosome 5, but is dis

197 a(2+) sensitivity and increased cross-bridge cycling (k(tr)) at submaximal [Ca(2+)].

198 he functional space of other eukaryotic cell-cycle kinases controlling DNA replication.

199 als were found to be dependent on underlying cycle length in a highly curvilinear fashion with the de

200 plating/stripping (10 mAh cm(-2) ), and long cycle life (over 10 000 cycles).

201 provides a versatile remedy for the limited cycle life of the Zn anode.

202 g high energy density, high safety, and long cycle life.

203 able-adjusted HRs between lifetime ovulatory cycles (LOC) and its components and ovarian cancer risk

204 he effect of subduction on the deep nitrogen cycle may be less important than has been suggested by p

205 a quantum system, adiabatically driven in a cycle, may acquire a measurable phase depending only on

206 dation activity and tricarboxylic acid (TCA) cycle metabolites were measured in cells collected from

207 cting stomatal behavior and improving carbon cycle modeling.

208 ch enable modeling of kinematic loops (e.g., cycling models) and complex anatomy (e.g., patellar moti

209 Minimizing the number and duration of design cycles needed to optimize hit or lead compounds into hig

210 G normalization after a median of 9 avelumab cycles; none subsequently relapsed.

211 The centriole duplication cycle normally ensures that centriole number is maintain

212 rmediates, their relevance for the catalytic cycle of [FeFe] hydrogenase, and novel strategies for ex

213 l the previously unrecognized conformational cycle of ABCG2.

214 and timings, which would affect the seasonal cycle of atmospheric radiocarbon concentrations recorded

215 gene transcription dynamics, we show that a cycle of fast exodus of nuclear YAP to the cytoplasm fol

216 ntally determined and investigated through a cycle of ligand-FEP calculations, validating the binding

217 P, which coordinate the assembly-disassembly cycle of neuronal SNARE complexes.

218 ronmental impacts throughout the entire life cycle of packaging and FSW were analyzed.

219 The erythrocytic cycle of Pbyop1Delta parasites is severely attenuated an

220 nd that individuals' ties undergo an initial cycle of rapid expansion and contraction.

221 In each half cycle of the transport process, there is a state in whic

222 17-2018), 1,493 participants with 6 or fewer cycles of attempt time were randomly assigned with 50% p

223 d this percentage increased to 60% after two cycles of blinatumomab; the percentage of patients with

224 (1:1) to either surveillance or four 21-day cycles of chemotherapy, using a minimisation algorithm w

225 ment in which plants were subjected to three cycles of drought.

226 ggest Arctic marine biomes persisted through cycles of glaciation, leading to unique assemblages in p

227 LM can be used to describe normal sleep-wake cycles of healthy adult dogs and the effects of physiolo

228 d 30, inhibit early steps of the replicative cycles of HIV-1 and EV-A71 by interacting with their res

229 lations, were employed for sampling multiple cycles of LIV-BPSS clamshell-like conformational changes

230 If >= 100 out of 125 patients completed 4 cycles of paclitaxel without dose delay, the regimen wou

231 ded 20 samples that required 30-39 threshold cycles of RT-qPCR to achieve a positive detection.

232 Two cycles of therapy were offered (cycle 1: CPX-351; cycle

233 al-interglacial period spanning four or five cycles of ~20,000 years.

234 eedbacks within the internal iron and sulfur cycling of the ocean.

235 torage-temperature, and repeated freeze-thaw cycles on circulating BDNF concentrations was evaluated.

236 (16 mg/kg of bodyweight, once weekly during cycle one, once every 3 weeks in cycles two through nine

237 f diversity at many levels-ranging from cell cycle organization to chromosome ploidy to replication m

238 the receptor tyrosine kinases, TP53 and cell-cycle pathways, and IDH1 R132.

239 ate a small interfacial resistance with good cycling performance at 35 degrees C.

240 are motility between cells in different cell-cycle phases and in cell-cycle arrest.

241 reased during mitosis relative to other cell cycle phases suggests that redox modifications could pla

242 mely shut-off of the pneumococcal competence cycle, preserving cell fitness.

243 to permanent state change in biogeochemical cycling, primary production, and biological diversity by

244 tural components that underly essential cell cycle processes, and influenced our thinking about cance

245 peratures have a profound impact on global N cycling processes with implications of a positive feedba

246 The chaperone protein SmgGDS promotes cell-cycle progression and tumorigenesis in human breast and

247 illin also affected networks related to cell cycle progression as well as connective tissue developme

248 loop between appressorium formation and cell cycle progression in U. maydis, which serves as a "toggl

249 ranscription factor NF-Y is crucial for cell-cycle progression in various types of cells.

250 paired growth is due to perturbation of cell cycle progression rather than induction of apoptosis.

251 ucial roles in cell differentiation and cell-cycle progression, and kinase dysregulation is associate

252 , increased Tnf expression, decreased a cell cycle regulator (Ccnb1), and increased apoptotic factors

253 Protein and transcript levels of cell cycle regulators were examined in breast cancer cells.

254 Cell-cycle regulatory proteins (p21(Cip1) /p27(Kip1) ) inhibi

255 rior results, HML and HMR had identical cell-cycle requirements for silencing establishment, with no

256 acts of fluoropolymers throughout their life cycle(s).

257 Analyses of the transport cycle show that serine phosphorylation abolishes the K(+

258 326 F g(-1) (419 F cm(-3)) and ultra-stable cycling stability (96.6% after 5000 cycles).

259 ic energy density (775 Wh kg(-1) ), and good cycling stability.

260 chromatin and kinetochores at distinct cell-cycle stages, revealing extensive reorganization of kine

261 -life of p53 and uses p53 to initiate a slow-cycling state following stress (DNA damage, targeted the

262 Estrous cycling status was evaluated in PND90 and PND365 rats.

263 raccumulation of negative regulators of cell cycle such as Wee1-like protein kinase (WEE1).

264 ndent kinases at distinct stages of the cell cycle, suppresses S-phase entry and promotes progression

265 lling a reorganization of the climate-carbon cycle system.

266 Moreover, we use cell cycle tags to reinstall cell cycle control to a deregula

267 ication, housing key steps in the virus life cycle that warrant further investigation.

268 feedbacks, mediated by the oxygen and sulfur cycles, that led to permanent state change in biogeochem

269 k to the original quinone, creating a futile cycle, the byproducts of which are deleterious reactive

270 During interphase of the eukaryotic cell cycle, the microtubule (MT) cytoskeleton serves as both

271 were administered at cycles 1-5, every three cycles thereafter during year 1, and every four cycles d

272 Due to their long and unique life cycles, these arthropods likely evolved robust epigeneti

273 als had an RT-PCR-positive viral test with a cycle threshold (C(T) ) of <35 or seroconverted during t

274 The overall mean difference in cycle threshold (C(T) ) values for the positive NPS and

275 Those with high cycle threshold are unlikely to have infectious potentia

276 nsistently yielded amplifiable RNA with mean cycle threshold differences of <3 over the various condi

277 f isolation/quarantine, (ii) whether the PCR cycle threshold value should be included on patient repo

278 e concentrations during the synaptic vesicle cycle to ensure normal synaptic transmission.

279 to polyamine biosynthesis to the methionine cycle to overcome stress.

280 gens are able to compartmentalize their life cycle to provide favorable conditions for replication an

281 using different IOP sampling rates and duty cycles, to characterize IOP dynamics.

282 acquired early during the evolution of rapid cycling trait in rice subspecies.

283 f T-PLL cells evoked higher-than-normal cell-cycle transition and profiles of cytokine release that r

284 lly recurrent prostate cancer (PCa), whereby cycling treatment on and off can reduce cumulative dose

285 ekly during cycle one, once every 3 weeks in cycles two through nine, and once every 4 weeks thereaft

286 ight cycles and 35-day cycles from the ninth cycle until disease progression, unacceptable toxicity,

287 with 40 mg of weekly dexamethasone in 28-day cycles until disease progression or up to 6 cycles after

288 It however suffers from a voltage decay upon cycling, urging for an in-depth understanding of the par

289 Although the ribulose monophosphate (RuMP) cycle used by methylotrophs to assimilate methanol diffe

290 The two states are cycled using an electrically controllable local-heating

291 devices; we will illustrate that the thermal cycling variations strongly determine the type of damage

292 echanistic insights into the viral infection cycle, very little is known about the location and foldi

293 on that is mediated by regulation of calcium cycling via 12,13-diHOME and NOS1.

294 d of a simple reductive quenching photoredox cycle, we have successfully harnessed this novel radical

295 ct by the carboxylate anion on the catalytic cycle, whereas 2-ethyl hexanoate minimizes this inhibito

296 stomatal opening and closing across the diel cycle, which conserves water and provides a means of mai

297 n and interrogated by the OFDR system for 11 cycles with a single laser scan.

298 ts, which play a key role in trace elemental cycles, with potentially important consequences for glob

299 ety vs decitabine 20 mg/m2 IV in the first 2 cycles, with similar efficacy.

300 down of the last relevant directed catalytic cycle within a dynamical system.

301 t studies indicate that the classical visual cycle works together with light-dependent processes in b

302 osystems in modulating global biogeochemical cycles, yet their biological communities and related car