ライフサイエンスコーパス: cyclic nucleotide-gated channel

1 of cyclic AMP and subsequent activation of a cyclic nucleotide-gated channel.

2 ar to the voltage-gated Ca2+ channel and the cyclic nucleotide-gated channel.

3 proteins coupled to cGMP binding domains or cyclic nucleotide gated channels.

4 emonstrated that AtCNGC1 and NtCBP4 are also cyclic nucleotide-gated channels.

5 activation of a nonselective current through cyclic nucleotide-gated channels.

6 and is controlled by cAMP, possibly through cyclic nucleotide-gated channels.

7 M Ca(2+), Mg(2+), or Sr(2+), the blockers of cyclic nucleotide-gated channels.

8 II activation, cAMP increase, and opening of cyclic nucleotide-gated channels.

9 nce (G(IRK)) or hyperpolarization-activated, cyclic nucleotide-gated channels.

10 n-activated cyclic nucleotide-modulated, and cyclic nucleotide-gated channels.

11 nism to modulate hyperpolarization-activated cyclic nucleotide-gated channels.

12 hate (cGMP)-dependent influx of Ca2+ through cyclic nucleotide-gated channels.

13 l transduction is unlikely to be mediated by cyclic-nucleotide-gated channels.

14 (+)-channels and hyperpolarisation-activated cyclic-nucleotide-gated channels.

15 n-activated HCN (hyperpolarization-activated cyclic nucleotide-gated) channels.

16 mma (Prkcc), and hyperpolarization-activated cyclic nucleotide-gated channel 1 (Hcn1)) that were cons

17 The gene, hyperpolarization-activated cyclic nucleotide-gated channel 1 (Hcn1), regulates neur

18 ingle QTG, Hcn1 (hyperpolarization-activated cyclic nucleotide-gated channel 1), which has been impli

19 Here, we report that CYCLIC NUCLEOTIDE-GATED CHANNEL 14 (CNGC14) is essential

20 m of the calmodulin 2 (CaM2) associates with CYCLIC NUCLEOTIDE GATED CHANNEL 15 (CNGC15s), closing th

21 function of the hyperpolarization-activated cyclic nucleotide-gated channel 2 (HCN2) are decreased i

22 ion of the HCN2 (hyperpolarization-activated cyclic nucleotide-gated channel 2) subunit of the Ih cha

23 rk4 cell death suppressors, we revealed that cyclic nucleotide-gated channel 20 (CNGC20) functions as

24 n channel, HCN4 (hyperpolarization-activated cyclic nucleotide gated channel 4), and the correspondin

25 noreactivity for hyperpolarization-activated cyclic nucleotide-gated channel 4 (HCN4) and the transcr

26 cell marker hyperpolarization-activated and cyclic nucleotide-gated channel 4 (HCN4) in Vsx1-null mi

27 potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4) locus of the mouse ge

28 oreactivity for hyperpolarization activated, cyclic nucleotide-gated channel 4, were located in the b

29 sms proposed for hyperpolarization-activated cyclic nucleotide-gated channels(5), and may represent a

30 ity of various Ca(2+)-gated channels such as cyclic nucleotide gated channel 6 (CNGC6), CNGC14 and au

31 ctivity of the cyclase in the dark increased cyclic nucleotide-gated channel activity and elevated th

32 cAMP opens cyclic nucleotide-gated channels allowing a Ca(2+) influ

33 for G(Olf,) adenylate cyclase 3 (Adcy3) and cyclic nucleotide-gated channel alpha 2 (Cnga2), key mol

34 We expressed the rat olfactory cyclic nucleotide-gated channel alpha subunit in Xenopus

35 localization and trafficking process of rod cyclic nucleotide-gated channel alpha-subunit (CNGA1), a

36 omparison to the highly homologous olfactory cyclic nucleotide-gated channel alpha-subunit, which doe

37 onstrate that mice lacking functional CNGA2 (cyclic nucleotide-gated channel alpha2), which is requir

38 ut mice have been produced: a knockout for a cyclic nucleotide-gated channel and a G(olf) knockout.

39 e NaK selectivity filter resembles that of a cyclic nucleotide-gated channel and its structure may re

40 Slow gating kinetics of the cyclic nucleotide-gated channel and the detection of sin

41 suggest that in tissues where they co-exist, cyclic nucleotide-gated channels and Ca2+-sensitive aden

42 are responsible for the direct activation of cyclic nucleotide-gated channels and for modulation of t

43 at members of Ca(2+) channels, including the cyclic nucleotide-gated channels and glutamate receptor-

44 to stimulation, Ca(2+) enters the cilia via cyclic nucleotide-gated channels and is extruded by Na(+

45 portant role for hyperpolarization-activated cyclic nucleotide-gated channels and the cAMP/protein ki

46 polypeptide, BCNG-1, is distantly related to cyclic nucleotide-gated channels and the voltage-gated c

47 show that degenerating cones have functional cyclic-nucleotide-gated channels and can continue to giv

48 es more potent than cyclic GMP in activating cyclic-nucleotide-gated channels and cGMP-dependent prot

49 ion permeation, gating and channelopathy of cyclic-nucleotide-gated channels and cyclic nucleotide m

50 nd inner segment hyperpolarization-activated cyclic nucleotide-gated channels, and from ATP-dependent

51 e, raising cyclic GMP concentration, opening cyclic nucleotide-gated channels, and increasing circula

52 hannels, CLC chloride transporters/channels, cyclic nucleotide-gated channels, and ionotropic glutama

53 Thus, we propose that native rod cyclic nucleotide-gated channels are arranged with like

54 Retinal rod cyclic nucleotide-gated channels are composed of alpha a

55 Cyclic nucleotide-gated channels are important in visual

56 Cyclic nucleotide-gated channels are key molecular eleme

57 These cyclic nucleotide-gated channels are located at the nucl

58 Cyclic nucleotide-gated channels are nonselective cation

59 Cyclic nucleotide-gated channels are tetramers and, in t

60 ings, we now show that retinal and olfactory cyclic-nucleotide-gated channels are activated by a cycl

61 Cyclic-nucleotide-gated channels are essential for visio

62 ir 3.x) channels, like the distantly related cyclic nucleotide-gated channels, are tetramers and exhi

63 ells, we used the patch-cramming method with cyclic nucleotide-gated channels as real-time biosensors

64 Cone density in cone cyclic nucleotide-gated channel B subunit-deficient and

65 Further, cone cyclic nucleotide-gated channel B subunit-deficient mice

66 Mutations in cyclic nucleotide-gated channel beta 1 (CNGB1) cause app

67 reatment of retinitis pigmentosa (RP) due to cyclic nucleotide-gated channel beta 1 (CNGB1) mutations

68 The canine homolog of the cyclic nucleotide-gated channel beta-subunit gene (CNGB3

69 cs analysis revealed the z13 receptor as the cyclic nucleotide-gated channel beta3, a sorting pathway

70 with guanidinium, an ion which permeates the cyclic nucleotide-gated channel but does not support Na(

71 t calcium concentration ([Ca2+]i) by closing cyclic nucleotide-gated channels but can also increase [

72 via Ca(2+)-dependent GCAP proteins, and (3) cyclic nucleotide-gated channels by binding of Ca(2+)-ca

73 underlie previously reported potentiation of cyclic nucleotide-gated channels by sulfhydryl-reactive

74 s, sodium transporters, calcium antiporters, cyclic nucleotide-gated channels, cation diffusion facil

75 In cyclic nucleotide-gated channels (CNG), direct binding o

76 eptor for relaxin-3 (RXFP3) and a functional cyclic nucleotide-gated channel (CNGA), which suggests d

77 A mutation in a cyclic nucleotide-gated channel (CNGA1) is associated wi

78 locking adenylyl cyclase or knocking out the cyclic nucleotide-gated channel CNGA2 eliminates the odo

79 How the nuclear-localized ion channels, cyclic nucleotide-gated channel (CNGC) 15 and DOESN'T MA

80 e indicates that pollen tube growth requires cyclic nucleotide-gated channel (CNGC) 18.

81 Cyclic nucleotide-gated channel (CNGC) family members me

82 We report here that a cyclic nucleotide-gated channel (CNGC) protein, CNGC15,

83 supply is sufficient, two genes that encode cyclic nucleotide-gated channel (CNGC) proteins, CNGC2 a

84 he DOES NOT MAKE INFECTIONS 1 (DMI1) and the cyclic nucleotide-gated channels (CNGC) 15s.

85 We report that pollen-tube-specific cyclic nucleotide-gated channels (CNGC18, CNGC8, and CNG

86 lecules for CPK32 led to identification of a cyclic nucleotide-gated channel, CNGC18, as an interacti

87 Plant cyclic nucleotide gated channels (CNGCs) facilitate cyto

88 Cyclic nucleotide-gated channels (CNGCs) are nonspecific

89 Cyclic nucleotide-gated channels (CNGCs) have been impli

90 Cyclic nucleotide-gated channels (CNGCs) on the dendriti

91 Cyclic nucleotide-gated channels (CNGCs) transduce exter

92 ith structural similarities to cloned animal cyclic nucleotide-gated channels (CNGCs).

93 In this study, we identified the cyclic nucleotide-gated channel complex CNGC2-CNGC4 as e

94 ence that native hyperpolarization-activated cyclic nucleotide-gated channel complexes (HCN1-4) also

95 ponse relations for a large number of single cyclic nucleotide-gated channels composed of the bovine

96 deactivation of hyperpolarization-activated cyclic nucleotide-gated channels conducting the hyperpol

97 Cyclic nucleotide-gated channels contain four ligand-bin

98 Cyclic nucleotide-gated channels contain four subunits,

99 ons, both BK and hyperpolarization-activated cyclic nucleotide-gated channels contributed.

100 n vertebrate visual and olfactory systems, a cyclic nucleotide-gated channel couples receptor activat

101 coding intraflagellar transport proteins and cyclic nucleotide gated channels, demonstrating that C.

102 y adaptation within neurons that require the cyclic nucleotide-gated channel for olfaction; in these

103 permeable to Ca(2+) We demonstrate that the cyclic nucleotide-gated channels form a complex with the

104 ere, we study ligand binding of a tetrameric cyclic nucleotide-gated channel from Mesorhizobium loti

105 icle electron cryo-microscopy structure of a cyclic-nucleotide-gated channel from Caenorhabditis eleg

106 +) and dendritic hyperpolarization-activated cyclic nucleotide-gated-channel function is reduced in E

107 emaker gene, the hyperpolarization-activated cyclic nucleotide-gated channel gene (HCN2), was studied

108 PSKR1 is coexpressed with the CYCLIC NUCLEOTIDE-GATED CHANNEL gene CNGC17.

109 y overexpressing hyperpolarization-activated cyclic nucleotide gated channel genes responsible for th

110 Recent advances of plant cyclic nucleotide-gated channels give new insight into t

111 Hyperpolarization-activated cyclic nucleotide-gated channel (HCN) 4 is a major subun

112 assium-sensitive hyperpolarization-activated cyclic nucleotide-gated channel (HCN) conductance in the

113 ockade of septal hyperpolarization-activated cyclic nucleotide-gated channels (HCN) impairs hippocamp

114 abolished by the hyperpolarization-activated cyclic-nucleotide-gated channel (HCN)-specific antagonis

115 rted for the hyperpolarization-activated and cyclic nucleotide-gated channel HCN2 in the family of so

116 kedly depends on hyperpolarization-activated cyclic nucleotide-gated channel (HCNC) activation.

117 y understood how hyperpolarization-activated cyclic nucleotide-gated channels (HCNs) function.

118 augmentation of hyperpolarization-activated cyclic nucleotide-gated channels (Ih or HCN channels).

119 mpartmentalization allows the confinement of cyclic nucleotide-gated channel in the PM, while prevent

120 We show that three cyclic nucleotide-gated channels in Medicago truncatula

121 CNGB3 encodes the beta-subunits of cyclic nucleotide-gated channels in the photoreceptor pl

122 We find no evidence for cyclic nucleotide-gated channels in VNO neurons under a

123 t structural and functional understanding of cyclic nucleotide-gated channels, in this study we exper

124 lts in increased cAMP production, opening of cyclic nucleotide-gated channels, influx of Ca2+ and Na+

125 -br-cGMP were reversed by L-cis-diltiazem, a cyclic nucleotide-gated channel inhibitor, as well as by

126 dour stimulates the influx of Ca(2+) through cyclic nucleotide-gated channels into the small volume w

127 First, a cationic, Ca(2+)-permeable cyclic nucleotide-gated channel is opened following odor

128 The activation of a cyclic nucleotide-gated channel is the final step in sen

129 Activation of cyclic nucleotide-gated channels is thought to involve t

130 e suggests that a subset of this family, the cyclic nucleotide-gated channels, may deviate from this

131 Although cyclic nucleotide-gated channels mediate sensory transdu

132 Caenorhabditis elegans cyclic nucleotide-gated channel mutants respond normally

133 that it was produced by ion flux through the cyclic nucleotide-gated channels of the outer segment; h

134 to diffuse into the cilium and activate the cyclic nucleotide-gated channels on the plasma membrane.

135 cGMP is the natural activator of the cyclic nucleotide-gated channel originally isolated from

136 el and its structure may represent that of a cyclic nucleotide-gated channel pore.

137 hannels, which include the K+, Ca2+, Na+ and cyclic nucleotide-gated channels, probably share a simil

138 interacted with hyperpolarization-activated cyclic nucleotide-gated channel proteins (HCN proteins)

139 ession of three CBPs including an isoform of cyclic nucleotide-gated channels (PvCNGC-A) and two hypo

140 tein kinase, which limits the conductance of cyclic nucleotide-gated channels, reducing the influx of

141 ndent protein kinase I (CaMKI) and the TAX-4 cyclic nucleotide-gated channel regulate gene expression

142 zed and evaluated for potency of blockade of cyclic nucleotide-gated channels relative to a multiply

143 noassay and membrane-delineated flow through cyclic nucleotide-gated channels, respectively.

144 In the present study we have employed a cyclic nucleotide-gated channel sensor to report acute c

145 sequence alignments between AQP1 and sensory cyclic-nucleotide-gated channels showed similarities bet

146 ger of Gata6 induces loss of hyperpolarizing cyclic nucleotide-gated channel, subtype 4 staining in t

147 node with some retention of hyperpolarizing cyclic nucleotide-gated channel, subtype 4 staining in t

148 diesterase 2a, cGMP-dependent kinase II, and cyclic nucleotide gated channel subunit A3 coupled to a

149 The olfactory cyclic nucleotide-gated channel subunit 1 (OCNC1) is req

150 ene encoding the hyperpolarization-activated cyclic nucleotide-gated channel subunit 2 (HCN2), an ion

151 channel M5 (TRPM5), is coexpressed with the cyclic nucleotide-gated channel subunit A2 in a subset o

152 sing the receptor guanylyl cyclase GC-D, the cyclic nucleotide-gated channel subunit CNGA3, and the c

153 sensory neurons by targeted mutagenesis of a cyclic nucleotide-gated channel subunit gene, OCNC1.

154 s the photoreceptors LITE and GUR-3, and the cyclic nucleotide-gated channel subunit TAX-2.

155 ha(olf), adenylyl cyclase III, the olfactory cyclic nucleotide-gated channel subunits, and olfactory

156 that tax-2 encodes a predicted subunit of a cyclic nucleotide-gated channel that is expressed in olf

157 genes of C. elegans encode two subunits of a cyclic nucleotide-gated channel that is required for che

158 odulation in hyperpolarization-activated and cyclic nucleotide-gated channels that display voltage-de

159 studied two inheritable cysteine mutants of cyclic nucleotide-gated channels that produce achromatop

160 on the sequence differences between CRP and cyclic nucleotide gated channel, three mutants of CRP we

161 ut independent of transducin that sensitizes cyclic nucleotide gated channels to cGMP and causes phot

162 response of ligand-binding proteins, such as cyclic-nucleotide-gated channels, to different biologica

163 sts of candidate channel subtypes including: cyclic nucleotide-gated channels, transient receptor pot

164 ng movements of the intracellular domains of cyclic nucleotide-gated channels using simultaneous site

165 volves the opening of hyperpolarization- and cyclic nucleotide-gated channels via cyclic nucleotide,

166 The cDNA coding for the rat olfactory cyclic nucleotide-gated channel was inserted into an ade

167 egion of the alpha subunit of the bovine rod cyclic nucleotide-gated channel was probed using cystein

168 channel appears to differ from the olfactory cyclic nucleotide-gated channel, which is also modulated

169 ion of homomeric and heteromeric retinal rod cyclic nucleotide-gated channels with the four ligand-bi