ライフサイエンスコーパス: cyclohexadiene

1 earlier for reactions starting with 1,4-d(2)-cyclohexadiene.

2 lace of benzene the nonaromatic analogue 1,3 cyclohexadiene.

3 l triflate precursors to cyclohexyne and 1,2-cyclohexadiene.

4 erric iron hydroxides in the presence of 1,4-cyclohexadiene.

5 nvolve quinones, hydrazines, thiols, and 1,3-cyclohexadiene.

6 ) ((Dip)Nacnac), Et ((Dep)Nacnac)) using 1,3-cyclohexadiene.

7 inylcyclobutene almost completely yields 1,3-cyclohexadiene.

8 yield) by thermolysis of (i)Pr(2)NPA in 1,3-cyclohexadiene.

9 asuring the kinetics of rearrangement in 1,4-cyclohexadiene.

10 matic isocyanides into highly functionalized cyclohexadienes.

11 the Birch reduction but does not afford 1,4-cyclohexadienes.

12 Birch reduction dearomatizes arenes into 1,4-cyclohexadienes.

13 and provides complex, synthetically valuable cyclohexadienes.

14 ng to produce a range of complex spirocyclic cyclohexadienes.

15 utilized and produce mixtures of trienes and cyclohexadienes.

16 lyzed cycloisomerization of siloxy enynes to cyclohexadienes.

17 range of highly functionalized 1,4- and 1,3-cyclohexadienes.

18 With 1,4-cyclohexadiene, 0.5 equiv of benzene is produced prior t

19 CBS-QB3 methods for the dimerization of 1,3-cyclohexadiene (1) reveal several highly competitive con

20 hydrogen abstraction from reaction with 1,4-cyclohexadiene (1,4-CHD) and (ii) the observation of 1,4

21 1 equiv of I2 in the presence of excess 1,4-cyclohexadiene (1,4-CHD) radical trap rapidly and near-q

22 nediynes or in their solutions in 10.6 M 1,4-cyclohexadiene (1,4-CHD)) strongly overestimate the reac

23 henolic hydroxyl groups into the ladder-type cyclohexadiene-1,4-diimine core, enabling efficient reso

24 1,4-phenylenediamine (I) and bis(10-(2-((2,5-cyclohexadiene-1,4-diylidene)dimalonitrile))decyl) disul

25 SAM on silver (or gold) was bis(20-(2-((2,5-cyclohexadiene-1,4-diylidene)dimalonitrile))decyl)) disu

26 ic pathway in which 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) is converted to 4-(

27 release 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate and carbon dioxide.

28 dration reaction of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate but also an accidental race

29 pendent 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase (MenD).

30 enzyme 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexadiene-1-carboxylate synthase, or MenD, catalyze

31 ile the other, which forms 1-hydroperoxy-2,4-cyclohexadiene (18), passes through the same diradical i

32 nic dehydration of 2-succinyl-6R-hydroxy-2,4-cyclohexadiene-1R-carboxylate (SHCHC) to 4-(2'-carboxylp

33 Although 1,4-cyclohexadienes 2, obtained through the Birch reduction

34 , abstracts H atoms from weak C-H bonds (1,4-cyclohexadiene, 2,4,6-(t)Bu3C6H2OH) to afford ferrous am

35 obutadiene, 65; 1,2-cyclopentadiene, 51; 1,2-cyclohexadiene, 32; 1,2-cycloheptadiene, 14; 1,2-cyclooc

36 metalation affords cis-3,6-disubstituted 1,4-cyclohexadienes (46-84%).

37 dagger) = 8.8 kcal/mol) to 1-hydroperoxy-2,5-cyclohexadiene (5), while the other, which forms 1-hydro

38 e (4), semibullvalene (5), and 5-ethynyl-1,3-cyclohexadiene (6), and C(8)H(10) hydrocarbons bicyclo[3

39 l ligand (Lax), toward three substrates: 1,4-cyclohexadiene, 9,10-dihydroanthracene, and triphenyl ph

40 For 1,3-cyclohexadiene a single transition structure for the [1,

41 ers, and three orthogonal functionalities, a cyclohexadiene, a nitrile, and an isocyanide.

42 the first 1,3-dipolar cycloadditions of 1,2-cyclohexadiene, a rarely exploited strained allene.

43 hydride-cyclopentadiene and maleic anhydride-cyclohexadiene adducts was accomplished with high stereo

44 yloxy)-1-propene result in 5-substituted-1,3-cyclohexadienes after removal of the metal.

45 t those obtained from reaction of 1 with 1,4-cyclohexadiene, allowed formulation of a detailed mechan

46 For example, the six-membered cyclohexadiene analogues exhibit Lewis-acidic behavior a

47 CH/Cope and CH insertion reactions with 1,3-cyclohexadiene and 1,4-cyclohexadiene, respectively.

48 ans-(DMPE)(2)Ru(H)(NH(2)) (1) dehydrogenates cyclohexadiene and 9,10-dihydroanthracene to yield benze

49 The poor reactivities of cyclohexadiene and cycloheptadiene with dienophiles that

50 ivatives (nitrile, acid, acid chloride) with cyclohexadiene and cyclopentadiene.

51 hout net epimerization, fragmentation to 1,3-cyclohexadiene and ethylene, migration to the original C

52 tration of the intrinsic reactivities of 1,4-cyclohexadiene and Hantzsch ester.

53 d Diels-Alder cycloaddition reaction between cyclohexadiene and methyl vinyl ketone is compared to th

54 er reactions of furans and pyrroles with 1,2-cyclohexadiene and oxa- and azaheterocyclic analogs proc

55 nate fluorene and reversibly deprotonate 1,3-cyclohexadiene and toluene.

56 these species also abstract H atoms from 1,4-cyclohexadiene and various phenol derivatives.

57 can be extended to other substrates such as cyclohexadiene and xanthene derivatives and can tolerate

58 vestigations of (i)Pr2NPA thermolysis in 1,3-cyclohexadiene and/or benzene-d6 are consistent with a m

59 earrangement of (aza) indazoles to diazo(aza)cyclohexadienes and (aza)cyclohexadienylidenes and route

60 rotoluene complex, which was elaborated into cyclohexadienes and cyclohexenes with ee's ranging from

61 ss to highly functionalized cyclohexenes and cyclohexadienes and is orthogonal to existing chemical a

62 he Diels-Alder reactions of cyclopentadiene, cyclohexadiene, and cycloheptadiene with a series of die

63 major product formed in the presence of 1,4-cyclohexadiene, and is believed to result from hydrogen

64 zes exogenous substrates, such as phosphine, cyclohexadienes, and isochroman to afford phosphine oxid

65 and flexible sigma-cyclic, pi-acyclic carbo-cyclohexadienes, and to "pro-aromatic" congeners, i.e. r

66 e demetalation with silver triflate, cis-1,4 cyclohexadienes are formed in yields ranging from 16 to

67 different solvents produced an intermediate cyclohexadiene as evidenced by UV/vis, IR, and 1H NMR sp

68 rogenation of 1,1-diphenylethylene using 1,4-cyclohexadiene as the hydrogen source.

69 symmetrization and kinetic resolution of 1,4-cyclohexadienes by the chiral dioxirane was also found t

70 iving first the carbene and then coordinated cyclohexadiene, C5 giving carbene, then diene, and then

71 he targeted (S)-N-acyl-protected 5-amino-1,3-cyclohexadiene carboxylates, key advanced intermediates

72 Although 1 oxidized PPh(3) and 1,4-cyclohexadiene catalytically, it did not epoxidize olefi

73 Hydrogen atom abstraction (HAA) from 1,4-cyclohexadiene (CD-H) by (dtbpe)Ni(NAr) to form a Ni(I)-

74 The 1,4-diacyloxylation of 1,3-cyclohexadiene (CHD) affords valuable stereochemically d

75 *) reactivity, using the autoxidation of 1,4-cyclohexadiene (CHD) as convenient HOO(*) source in chlo

76 s and even cocrystallizes with a molecule of cyclohexadiene (CHD) in its crystallographic unit cell t

77 on of electron density when the molecule 1,3-cyclohexadiene (CHD) is optically excited.

78 ular dynamics simulations of one and two 1,3-cyclohexadiene (CHD) molecule(s) reacting with the Si(10

79 was found to transfer P2 efficiently to 1,3-cyclohexadiene (CHD), 1,3-butadiene (BD), and (C2H4)Pt(P

80 fin-cyclopentadiene (CpH), cyclopentene, 1,4-cyclohexadiene (CHD), or cyclohexene-showed that, with t

81 DbetaM; E.C. 1.14.17.1)/1-(2-aminoethyl)-1,4-cyclohexadiene (CHDEA) reaction partitions between side

82 xides and aziridines derived from homochiral cyclohexadiene cis-diols.

83 ly formed by transfer hydrogenation from 1,4-cyclohexadiene (commonly included in such reactions), th

84 ophiles to form 5-substituted 3,4-eta(2)-1,3-cyclohexadiene complexes in good yield (42-70%).

85 K to reform the corresponding isobutene and cyclohexadiene complexes, by simple application of vacuu

86 Kinetic studies, as a function of 1,4-cyclohexadiene concentration, revealed retro-Bergman rin

87 solution cyclizations in the presence of 1,4-cyclohexadiene confirmed C(1)-C(6) Bergman cyclization.

88 e ultrafast photoinduced ring-opening of 1,3-cyclohexadiene constitutes a textbook example of electro

89 ic extrusion of the titanium center delivers cyclohexadiene-containing products, while several distin

90 or the synthesis of trans-aminoalcohols on a cyclohexadiene core.

91 1,5] hydrogen shifts in 1,3-cycloalkadienes (cyclohexadiene, cycloheptadiene, and cyclooctadiene).

92 y quantum mechanical tunneling that uses the cyclohexadiene derivative gamma-terpinene as the abstrac

93 Photooxygenation of a cyclohexadiene derivative gave a bicyclicendoperoxide, w

94 reaction attractive for a synthetic route to cyclohexadiene derivatives from alkynes.

95 sen was utilized to access 4-substituted-3,5-cyclohexadiene diol derivatives, which are valuable chir

96 The radical traps TEMPO and 1,4-cyclohexadiene do not inhibit the formation of 3; howeve

97 follows a stepwise diradical pathway to form cyclohexadiene endoperoxide with an activation barrier o

98 l during the intramolecular coupling between cyclohexadiene--Fe(CO)(3) complexes and pendant alkenes

99 pproach to a wide range of highy substituted cyclohexadienes for many subsequent synthetic applicatio

100 PF6)2 oxidizes 9,10-dihydroanthracene or 1,4-cyclohexadiene forming the terminal hydroselenide, [Ni(M

101 native sulfonamide N-H bonds leading to 1,4-cyclohexadiene-fused sultams.

102 h a 405 nm LED in the presence of THF or 1,4-cyclohexadiene, H0 accepts two H atoms to furnish H2.

103 synthesis of the dihydrocatechol 1 from 1,3-cyclohexadiene has also been developed.

104 y of the reaction of singlet oxygen with 1,3-cyclohexadiene has been made at the B3LYP/6-31G(d) and C

105 the three possible monodeuterium-labeled 1,3-cyclohexadienes have been followed in the gas phase at t

106 d arenes were selectively transformed to 1,4-cyclohexadienes in moderate to good yields in a complete

107 o be a synthetic precursor to functionalized cyclohexadienes: In solution, it selectively protonates

108 tion occurs via a hydrogen transfer from the cyclohexadiene intermediate to the maleimide derivative

109 Cyclohexadiene intermediates were not observed but were

110 d electrocyclic ring-opening reaction of 1,3-cyclohexadiene is a fundamental prototype of photochemic

111 1,2-Cyclohexadiene is generated in situ under mild condition

112 n contrast, the ring-opening reaction of 1,3-cyclohexadiene is shown to result in hot structures with

113 erted stereospecific cycloisomerization to a cyclohexadiene, is a reaction of great historical and pr

114 phile but not with the weak C-H bonds in 1,4-cyclohexadiene, it is proposed that the C-H cleavage occ

115 Similar experiments show that 1,3-cyclohexadiene likely reacts with P-nitroso phosphine ox

116 leophilic, oxidizable substrates such as 1,4-cyclohexadiene (M = Cu; 55%); however, in the presence o

117 Pro-aromatic and volatile 1-methyl-1,4-cyclohexadiene (MeCHD) was used for the first time as a

118 oligomers and polymer resembles that of poly(cyclohexadiene) more than poly(p-phenylene).

119 nts indicate that reaction between 5 and 1,4-cyclohexadiene occurs with a rate constant of approximat

120 drogenative cycloadditions of 1,2-diols with cyclohexadiene or norbornadiene are described.

121 ntation of the arenophile moiety affords 1,3-cyclohexadienes or 1,4-diaminocyclohex-2-enes, compounds

122 ng rapid access to highly functionalized 1,4-cyclohexadienes or cyclobutenes from the same precursors

123 l %) at ambient temperature to afford siloxy cyclohexadienes or the corresponding 1,2- and 1,3-cycloh

124 orobenzoquinone over its para-isomer and 1,3-cyclohexadiene over its 1,4-isomer, perhaps hinting at t

125 des to benzene gives the 3-(hydroxyaryl)-1,4-cyclohexadienes, predominantly.

126 *)(+), proceeds by a stepwise pathway to the cyclohexadiene product with an overall exothermicity of

127 reated as fleeting intermediates en route to cyclohexadiene products formed by formal cheletropic ext

128 of [(PIP)MoH(eta(5) -C(6) H(7) )] liberated cyclohexadiene, providing experimental support for a hig

129 of hexatriene radical cation 1(*)(+) to 1,3-cyclohexadiene radical cation 2(*)(+) was studied comput

130 on reactions with 1,3-cyclohexadiene and 1,4-cyclohexadiene, respectively.

131 mido aryl ortho isopropyl group, or from 1,4-cyclohexadiene, respectively.

132 iation and the structural opening of the 1,3-cyclohexadiene ring by the direct measurement of time-de

133 ic ring of the phenylethylamine substrate or cyclohexadiene ring of CHDEA.

134 migration of the boranediyl bridge from the cyclohexadiene ring to the remaining exocyclic alkyne re

135 rs, (C(6)H(6))(2), all featuring one or more cyclohexadiene rings trans-fused to 4- or 6-membered rin

136 ydrazine (S3), p-methoxyphenol (S4), and 1,4-cyclohexadiene (S5).

137 nd, similar to its relatives benzyne and 1,2-cyclohexadiene, should undergo strain-promoted reactions

138 nces the relative rates of reaction with 1,4-cyclohexadiene, specifically by gating access to complex

139 Unsaturated terpenes having a cyclohexadiene structure (e.g. terpinene) and minor cycl

140 olefin and sulfide sites as well as oxidize cyclohexadiene substrates to benzene in a formal H2-tran

141 Trapping experiments using 1,4-cyclohexadiene support the intermediacy of an aromatic d

142 fer to styrene, ethylene, neohexene, and 1,3-cyclohexadiene; the corresponding phosphiranes were isol

143 e of toluene for anisole, 1,3-butadiene, 1,3-cyclohexadiene, thiophenes, pyrroles, or furans resulted

144 upled with dehydrogenation of cyclohexane to cyclohexadiene, this allows for two successive KIEs to b

145 th the faster rate of HAT from indene versus cyclohexadiene, this trend is consistent with H(+) trans

146 demonstrate a novel method to synthesize 1,4-cyclohexadienes through a dearomative photocatalytic C-C

147 d ring-opening isomerization reaction of 1,3-cyclohexadiene to 1,3,5-hexatriene is a textbook example

148 om xanthene, 9,10-dihydroanthracene, and 1,4-cyclohexadiene to Cp(CO)2Os(*) and (eta(5)-(i)Pr4C5H)(CO

149 ymmetric P-nitrosophosphate reacted with 1,3-cyclohexadiene to form a mixture of diastereomeric cyclo

150 a H-atom abstraction (HAA) reaction with 1,4-cyclohexadiene to give the diamagnetic FLP-NOH product 3

151 ol, including 9,10-dihydroanthracene and 1,4-cyclohexadiene to produce [M(II)H(3)1(OH)](2-) and the a

152 Cluster 2 abstracts hydrogen atoms from 1,4-cyclohexadiene to yield the corresponding anilido comple

153 rgoes a H-atom abstraction reaction with 1,4-cyclohexadiene to yield the respective diamagnetic FLP-N

154 ith the commercially available 1-methoxy-1,3-cyclohexadiene to yield the resultant tetra-ortho-substi

155 ex and mild isomerization of redox-inert 1,4-cyclohexadienes to reducible 1,3-cyclohexadienes without

156 f the title compounds in the presence of 1,4-cyclohexadiene trap led to the formation of respective t

157 es were probed, most of which-except for 1,3-cyclohexadiene-underwent a clean Diels-Alder reaction an

158 provide functionalized cycloheptadienes and cyclohexadienes upon electrophilic capture.

159 ted electrons to convert inert arenes to 1,4-cyclohexadienes-valuable intermediates for building mole

160 lyzed Diels-Alder reaction of indole and 1,3-cyclohexadiene was studied by a combination of experimen

161 When hydrogen abstraction from 1,4-cyclohexadiene was studied in the presence of LiClO(4) a

162 for reaction of 5 with diethylamine and 1,3-cyclohexadiene were determined to be (1.3 +/- 0.5) x 10(

163 concentrations of external H-atom donor (1,4-cyclohexadiene) were performed to gain further insight i

164 et hypersurface and leads to an intermediate cyclohexadiene which undergoes a 1,5-hydrogen shift to r

165 facile electrocyclic ring closure to form a cyclohexadiene, which goes on to form anilines with a hi

166 ther comparable to or more reactive than 1,4-cyclohexadiene, which is one of the most reactive substr

167 example of the ring-opening reaction of 1,3-cyclohexadiene, which proceeds through two conical inter

168 ddition/elimination proceeds yielding chiral cyclohexadienes, which are then aromatized.

169 Anisole was also reduced to 1-methoxy-1,4-cyclohexadiene with 2.5 Li/mol of anisole.

170 ient triplet state photocycloaddition to 1,4-cyclohexadiene with formation of 1,5-diaryl substituted

171 been developed to transform symmetrical 1,4-cyclohexadienes with attached aryl halides into phenanth

172 ene (CpH), cyclopentene (c-C(5)H(8)) and 1,4-cyclohexadiene, with intriguing selectivity.

173 x-inert 1,4-cyclohexadienes to reducible 1,3-cyclohexadienes without a strong base in its oxidized th