ライフサイエンスコーパス: cyclopentene

1 pane which subsequently ring expanded to the cyclopentene.

2 ain cycloalkenes such as cis-cyclooctene and cyclopentene.

3 ring-expansion metathesis polymerization of cyclopentene.

4 selectivity is seen in the Heck coupling of cyclopentene.

5 henolysis of methyl oleate, cyclooctene, and cyclopentene.

6 le oxidation products of cyclopentadiene and cyclopentene.

7 -diacetoxy-3-pivaloxymethyl-4-(N-acetylamino)cyclopentene.

8 stems do rearrange photochemically to afford cyclopentenes.

9 (3 + 2) cycloaddition to deliver an array of cyclopentenes.

10 at the adjacent positions, into substituted cyclopentenes.

11 ereocontrolled preparation of trisubstituted cyclopentenes.

12 n of highly functionalized dihydrofurans and cyclopentenes.

13 dihydroxylation of appropriately substituted cyclopentenes.

14 ies that are readily cyclized to substituted cyclopentenes.

15 -diacetoxy-3-pivaloxymethyl-4-(N-acetylamino)cyclopentenes.

16 able to show that oxidative cleavage of the cyclopentene 1,5-CH insertion product could be used to p

17 with a cyclic olefin-cyclopentadiene (CpH), cyclopentene, 1,4-cyclohexadiene (CHD), or cyclohexene-s

18 rved on the bond-forming carbon atoms of the cyclopentene-1,3-dione and nitroalkane, respectively.

19 ymmetrization of prochiral 2,2-disubstituted cyclopentene-1,3-dione is catalyzed by a bifunctional te

20 amidation of the prochiral 2,2-disubstituted cyclopentene-1,3-dione with N-methoxybenzamide has been

21 g., methylmaleimide, maleic anhydride, and 4-cyclopentene-1,3-dione) with an ethylene glycol suspensi

22 was identified as 2,2,4-tribromo-5-hydroxy-4-cyclopentene-1,3-dione, which is an analogue to several

23 eviously described 2,2,4-trihalo-5-hydroxy-4-cyclopentene-1,3-diones in drinking water.

24 al C(sp(2))-H alkylative desymmetrization of cyclopentene-1,3-diones using nitroalkanes as the alkyla

25 enacylbenzothiazolium bromides and prochiral cyclopentene-1,3-diones.

26 s in formation of certain compounds (e.g., 2-cyclopentene-1,4-dione) and a decrease in others (e.g.,

27 -amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-++ +metha nol.

28 (1R, 4S)-(+)-4-Amino-2-cyclopentene-1-carboxylic acid ((+)-3), (4R)-(-)-4-amino

29 -carboxylic acid ((+)-3), (4R)-(-)-4-amino-1-cyclopentene-1-carboxylic acid ((-)-4), and d, l-3-amino

30 ntiomers of 3 and 4 and d, l-trans-4-amino-2-cyclopentene-1-carboxylic acid (5), are competitive inhi

31 -carboxylic acid ((-)-4), and d, l-3-amino-1-cyclopentene-1-carboxylic acid (6) are good substrates.

32 The resulting cyclopentene (14) is stereoselectively hydrogenated to p

33 The enantiomerically pure cyclopentene 15 was generated from ketone 14 by alkylide

34 amyl alcohol, which provides the substituted cyclopentene 2a in 95% yield and with 97:3 regioselectiv

35 Cyclopentenes 3 and 4 were formed both kinetically (3:4

36 esized cyclopentylidenes 1 and 2, as well as cyclopentenes 3 and 4, as novel ring-contracted analogue

37 ring of the target, unexpectedly provided a cyclopentene (67%), which arises from participation of t

38 ions of 4-acetoxy-1-(N-hydroxyphenyacetamido)cyclopentene (8).

39 eospecific synthesis of suitably substituted cyclopentenes, 8 and 10, as surrogates for either the L-

40 The corresponding cyclopentene analogues were previously reported to be in

41 Unlike the cyclopentene analogues, there appears to be sufficient r

42 ently reported Co-catalyzed reaction between cyclopentene and 1-phenyl-1-propyne.

43 gation of the coupling between a spirocyclic cyclopentene and 4-fluorophenyl diazonium species under

44 st of chiral derivatives of cyclopentane and cyclopentene and a chiral carbocyclic phosphonate.

45 arbonate display near planarity of the fused cyclopentene and benzene rings.

46 ere shown to prevent alkene isomerization in cyclopentene and cycloheptene starting materials.

47 embered cycloalkanones nucleophilically open cyclopentene and cyclohexene oxides in 57-76% yields and

48 acetoxy-substituted enyne-allenes, fused to cyclopentene and cyclohexene ring systems, were synthesi

49 ith binding energies of 57 and 62 kJ/mol for cyclopentene and cyclohexene, respectively, with transit

50 having barriers of 17.8 and 19.3 kJ/mol for cyclopentene and cyclohexene, respectively.

51 method for the synthesis of polysubstituted cyclopentene and cyclopenta[ b]carbazole derivatives thr

52 allows the synthesis of diversified aminated cyclopentene and cyclopentane derivatives being relevant

53 Pr*CPh(3))CuH catalyzes the hydroboration of cyclopentene and methylcyclopentene with pinacolborane.

54 hear rheology, from 13 to 50 kg.mol(-1) with cyclopentene and substituted cyclohexene moieties being

55 reaction for the synthesis of functionalized cyclopentenes and cyclohexenes is described.

56 Trifluoroacetoxylation of monosubstituted cyclopentenes and cyclohexenes proceeds with excellent r

57 cyclobutylcarbene to bicyclo[2.1.0]pentane, cyclopentene, and methylenecyclobutane were computed and

58 lvent on the base-catalyzed isomerization of cyclopentene- and cyclohexene oxides.

59 Commencing from cyclohexenone, a key cyclopentene annulation followed by ring-expansion resul

60 eoselectivities of dihydroxylations of fused cyclopentenes are influenced by the conformational rigid

61 on a series of mono, di-, and trisubstituted cyclopentenes are reported in which trans-vicinal-additi

62 f 1 via aziridine opening of tosyl-activated cyclopentene aziridine 2 and optical resolution of racem

63 Nonsymmetric cyclopentene-based dithienylethenes, containing both thi

64 composed of bis(5-pyridyl-2-methyl-3-thienyl)cyclopentene (BPMTC) and tetrakis(4-carboxyphenyl)porphy

65 ds in cyclic olefins, cyclopentadiene (CpH), cyclopentene (c-C(5)H(8)) and 1,4-cyclohexadiene, with i

66 to produce 1,3-cyclopentadiene (c-C(5)H(6)), cyclopentene (c-C(5)H(8)), and molecular hydrogen (H(2))

67 (PeCHC, by hydrogenation of PvCHC), and poly(cyclopentene carbonate) (PCPC).

68 ole-fused azepines by (4 + 3) annulation and cyclopentene carboxylates by (4 + 1) annulation; the rat

69 lly attractive and enantiomerically enriched cyclopentene carboxylic acids with two stereogenic cente

70 sulted in the formation of the corresponding cyclopentene-containing CH-insertion product in 62-69% y

71 on derivative 7a that has a relatively rigid cyclopentene core structure exhibits the strongest inhib

72 mperature and dilution) that drives RCM into cyclopentenes (CPs), each bearing one of the original PS

73 furnish the gem-difluoromethylene containing cyclopentene, cycloheptene, and cyclooctene derivatives

74 allylic and homoallylic amines (derived from cyclopentene, cyclohexene, and cycloheptene) have been i

75 te (PO.+ClO4(-)) added stereospecifically to cyclopentene, cyclohexene, cycloheptene, and 1,5-cyclooc

76 reactions between the ion 5 (m/z = 261) and cyclopentene, cyclohexene, cycloheptene, and cyclooctene

77 tion efficiencies for pi-ligand exchange for cyclopentene, cyclohexene, cycloheptene.

78 ano-2(E)-propenylcyclopropane [(+)-cis-1] to cyclopentenes definitively contraindicates the usefulnes

79 lobutene (DeltaE++ = 13.7 kcal/mol) than for cyclopentene (DeltaE++ = 12.1 kcal/mol), reflecting the

80 l4, the cyclopropane dicarboxylates afforded cyclopentene derivatives through ring opening followed b

81 Polysubstituted cyclopentene derivatives were produced through 4pai elec

82 l condensation to furnish highly substituted cyclopentene derivatives with good to high enantioselect

83 ring replacement by chiral cyclopentane and cyclopentene derivatives, and phosphate replacement by p

84 molecular annulation of 12 1,3-disubstituted cyclopentenes, derived from (+)-vince lactam, resulted i

85 of the intermediate epoxides are observed in cyclopentene-derived and cycloheptene-derived allylic am

86 r, by subsequently considering a pyrrolinium-cyclopentene design, it is also found that the introduct

87 n eight steps from a readily available known cyclopentene-diol derivative.

88 g current and sample biasing conditions, the cyclopentene dissociation products are isolated and then

89 ibias STM and density functional theory, the cyclopentene dissociation products are shown to consist

90 presence of one or two methyl groups on the cyclopentene double bond, in comparison to the rate of t

91 opentenone) and symmetrical (cyclohexene and cyclopentene) ethene bridges.

92 the kinetic pathway accounted for the 93% of cyclopentene formation at 40 degrees C.

93 t :CH-group favors bicyclo[2.1.0]pentane and cyclopentene formation.

94 The synthesis began with 1-pyrrolidino-1-cyclopentene from which an intermediate possessing the t

95 provides access to cis-1,3,4-trisubstituted cyclopentenes from enals and chalcone derivatives with h

96 n, and turnover-limiting displacement of the cyclopentenes from palladium.

97 Several cyclopentene GABA analogues were synthesized as conforma

98 annulation products including trisubstituted cyclopentenes, gamma-lactams, and bicyclic beta-lactams.

99 atrices containing either cyclopentadiene or cyclopentene have led to the first observation of severa

100 the synthesis of several functionalized aryl cyclopentenes in good to excellent diastereoselectivitie

101 active, and allowed the synthesis of 1,2-BN-cyclopentenes in one step with good to excellent yields.

102 ted alkyne leads to the formation of various cyclopentenes in up to 99% yield and 99:1 er.

103 esizing different carboxaldehydes, including cyclopentene, indene, dihydrofuran, benzofuran, dihydrop

104 Quantitative (1)H NMR kinetic studies on cyclopentene insertion into Cu-H complexes to form the c

105 amined for the oxidative cleavage of the key cyclopentene intermediate and we found that RuCl3/NaIO4

106 ive vinylation that provides quick access to cyclopentene intermediates containing all of the carbons

107 nges to its stable and highly functionalized cyclopentene isomer in an unprecedented metal-free proce

108 reover, the final amino acid products with a cyclopentene moiety can be further derivatized, opening

109 Subsequent epoxidation of the cyclopentene moiety in 8 was accomplished by treatment o

110 triphosphate complex also indicated that the cyclopentene moiety of the bound E-CFCP-TP is slightly s

111 suring the electrical properties of isolated cyclopentene molecules adsorbed to the degenerately p-ty

112 show that current-voltage curves on isolated cyclopentene molecules are reproducible and possess negl

113 Dissociation of individual cyclopentene molecules on the Si(100) surface is induced

114 The cyclopentene obtained from the PPh3-catalyzed reaction o

115 While demonstrated here for cyclopentene on Si(100), this feedback-controlled approa

116 ished that vinylcyclopropanes ring-expand to cyclopentenes on direct irradiation.

117 Furthermore, copolymerization of cyclopentene oxide (CPO) and CO2 was performed, resultin

118 ivity of 2500 h(-1) and >99% selectivity for cyclopentene oxide and CO(2).

119 via anti beta-elimination, as presumably do cyclopentene oxide and other epoxides.

120 Cyclopentene oxide instead undergoes alpha-elimination t

121 In HMPA, cyclopentene oxide undergoes beta-elimination.

122 omparison, the base-induced isomerization of cyclopentene oxide, which proceeds via alpha-elimination

123 ed to the stereoselective synthesis of spiro(cyclopentene)oxindoles with trisubstituted cyclopentene

124 ant A, vinylcyclopropane photoproduct B, and cyclopentene photoproduct C.

125 was determined that direct formation of the cyclopentene photoproduct proceeds more rapidly than the

126 energetic barrier, and the vinylcyclopropane-cyclopentene rearrangement proceeds through different me

127 anes and a subsequent mild vinylcyclopropane-cyclopentene rearrangement promoted by MgI(2).

128 rocyclic carbene-catalyzed vinylcyclopropane-cyclopentene rearrangement that involves a mutistep oxid

129 g followed by cyclization (vinylcyclopropane-cyclopentene rearrangement).

130 Further reaction of seleniranium 6 with cyclopentene resulted in further pi-ligand exchange givi

131 We synthesized key analogues to pinpoint the cyclopentene ring double bond as a source of reactivity

132 rbon double bond incorporated as part of the cyclopentene ring favors the formation of the correspond

133 The second plan deferred oxidation of the cyclopentene ring in 46 to a later stage of molecular co

134 rmosets through exclusive reformation of the cyclopentene ring in DCPD, then linear polyDCPD chains c

135 er modified derivatives are known, where the cyclopentene ring structure is additionally modified by

136 , with two adjacent quarternary carbons in a cyclopentene ring, was accomplished in 13.5% overall yie

137 les or by the subsequent modification of the cyclopentene ring.

138 de precursor, epoxyqueuosine, to yield the Q cyclopentene ring.

139 ds in which the cis double bond is part of a cyclopentene ring.

140 lack stereoselectivity when more substituted cyclopentene rings are targeted.

141 Cyclopentene rings possessing a chiral quaternary center

142 ereoselective rearrangement cascade toward a cyclopentene scaffold has also been demonstrated.

143 road scope for tetrasubstituted olefins in a cyclopentene scaffold, generating cyclopentanol products

144 myl side chain is connected to the Queuosine cyclopentene side chain, is unknown.

145 In addition to monocyclic cyclopentenes, spirocyclic and bicyclic ones are formed

146 Use of a stereospecifically deuterated cyclopentene substrate reveals that four of the five cat

147 The substituted cyclopentene substrates are derived from acylnitroso cyc

148 luoroborate (DMTSF)/NaN(3) with a variety of cyclopentene substrates has been carried out, and the ef

149 n-selective approach of electrophiles to the cyclopentene system.

150 th olefins has been developed that generates cyclopentenes that bear nitrogen-, phosphorus-, oxygen-,

151 With cyclopentene, the unsymmetrical 1,4-dihydropyridazine li

152 dehydrogenation, providing difunctionalized cyclopentenes through tandem dehydrogenation-olefination

153 yield), while ethenolysis of 10,000 equiv of cyclopentene to 1,6-heptadiene could be carried out with

154 the activated allylic C-H bonds, going from cyclopentene to cyclooctene.

155 Unusually, the digermyne also reacted with cyclopentene to give the same dehydroaromatization produ

156 n versus anti oxidative addition of 3-chloro-cyclopentene to Pd(0)L(n) was investigated using density

157 or skeletal reorganization that converts the cyclopentenes to the pentacyclic structures of the natur

158 kynyliodonium salt --> alkylidenecarbene --> cyclopentene transformation to convert a relatively simp

159 initiate an unexpected vinylcyclopropane --> cyclopentene type rearrangement, which occurs via a radi

160 on and in an analogue compound formed by two cyclopentene units linked by a norbornyl bridge, IET pro

161 o(cyclopentene)oxindoles with trisubstituted cyclopentene units.

162 These alkyne-tethered cyclopentenes upon [Au]/[Ag] catalysis lead to substitut

163 densely functionalized chiral d-lactones and cyclopentenes using carbene organocatalysis.

164 Allenoates and enones form cyclopentenes via a phosphine-catalyzed [3 + 2] cycloadd

165 ding biologically relevant gem-difluorinated cyclopentenes via alpha,alpha-difluoroketone scaffolds.

166 Cyclopentene was shown to undergo efficient coupling und

167 The enantiomeric cyclopentenes were further elaborated to incorporate an

168 The disubstituted cyclopentenes were obtained in good yields and excellent

169 s provides 1,1-alkyne (aldehyde)-substituted cyclopentenes wherein enynals act as electrophiles.

170 partners can be employed, thereby generating cyclopentenes which bear a fully substituted stereocente

171 and gives access to functionalized bicyclic cyclopentenes, which can be converted into other five-me

172 provide anti-1,4- and syn-1,4-disubstituted cyclopentenes while regenerating a hydroxamic acid moiet

173 of the highest occupied molecular orbital of cyclopentene with respect to the Fermi level of the sili

174 te scope and delivers a library of decorated cyclopentenes with loadings of SmI(2) as low as 15 mol %

175 opentylethylene, as well as for 1-hexene and cyclopentene, yields of corresponding aziridines vary fr