ライフサイエンスコーパス: cyclophane

1 sides inside the cavity of the tetracationic cyclophane.

2 uppressed by linking the PTZ units to form a cyclophane.

3 ystem is achieved with the coronene bisimide cyclophane.

4 ere [L(bis) ](-) is a bis(beta-diketiminate) cyclophane.

5 ondensation method produced alpha-Me beta-Me cyclophane.

6 and phenylene ring in the closest orthogonal cyclophane.

7 gs, as well as by the strain inherent in the cyclophane.

8 sides inside the cavity of the tetracationic cyclophane.

9 thin the cavity of an extended tetracationic cyclophane.

10 C3 structure is related to known meta-(1,3,5)cyclophanes.

11 lophanes were formed in preference to the [n]cyclophanes.

12 mation effect was also noticed in one of the cyclophanes.

13 than viologens, which make good pi-acceptor cyclophanes.

14 e useful for the creation of diverse peptide cyclophanes.

15 f positively charged polycationic open-shell cyclophanes.

16 e stability and reactivity of terpenoid para-cyclophanes.

17 Naphthalenophanes are a special type of cyclophanes.

18 cal properties of the extended tetracationic cyclophanes.

19 the reaction of propylene oxide, CO(2), and cyclophane 1 can follow the mechanistic path 1, whereas

20 e (3) was found to have more reactivity with cyclophane 1 compared to the other epoxides.

21 Cyclophane 1 is the first example of a cyclophane to act

22 Cyclophane 1, which can form a N heterocyclic carbene, w

23 However, cyclophane 1, which possesses a 3D geometry, can form th

24 distance of the dianion and dication of the cyclophane 14 compared to that of its neutral counterpar

25 We report the synthesis of cyclophanes 18-20 by ester-forming macrocyclization reac

26 In the neutral cyclophanes 18-20, the 9,10-bis(1,3-dithiol-2-ylidene)-9

27 he properties of Cy3R were compared to a new cyclophane-[2]rotaxane (Cy2R) that has the same cyclopha

28 Cyclophane-[2]rotaxane 1 efficiently transports fluoresc

29 art, underwent benzannulation to produce the cyclophane 28 brought additional support for the necessi

30 ciation constants for the cyclophane itself, cyclophane 3, are smaller.

31 l hydrocarbon propeller-shaped D3h-symmetric cyclophane (3), "anthraphane", was prepared through a re

32 Two very large cyclophanes (3, C(132)H(92)O(8)S(4); 4, C(172)H(120)O(8)

33 sent, in this report, the first example of a cyclophane-[3]rotaxane (Cy3R), which has two wheels and

34 The triple-decker cyclophane 8 has planar top and bottom COT rings, while

35 The cyclophanes all adopt butterfly-like conformations in th

36 % macrocycles) and up to 30% of a 6-membered cyclophane, all under nonhigh-dilution concentrations (3

37 Two of the cyclophanes also contain a (S)-(valine-leucine-alanine)

38 lene) (CBPQT4+) as the pi-electron-accepting cyclophane and 1,5-dioxynaphthalene (DNP)-containing mac

39 he careful consideration of the anatomy of a cyclophane and the classification of general synthetic a

40 on complexes consisting of the tetracationic cyclophane and the corresponding guests of different siz

41 The (super)structures of the reduced cyclophane and this 1:1 complex in the solid state devia

42 omaticity of doubly [5]helicene-bridged (1,4)cyclophane and triply [5]helicene-bridged (1,3,5)cycloph

43 However, the discovery of new, diverse cyclophanes and derivatives has been hindered by synthes

44 transfer between the extended tetracationic cyclophanes and perylene diimide is ultrafast and quanti

45 4 + 2]-cycloaddition reactions between these cyclophanes and tetracyanoethylene, which occur concerte

46 naphthalene-1,8:4,5-bis(dicarboximide) (NDI) cyclophanes and the characterization of four of their el

47 Despite their different structures, the cyclophanes and their nonbridged precursors have similar

48 stem to have been incorporated into numerous cyclophanes) and ending with hexabenzo[bc,ef,hi,kl,no,qr

49 lene recognition sites for the tetracationic cyclophane, and the other, tetrathiafulvalene and butadi

50 reaction of a vinyl sulfone to construct the cyclophane architecture of the natural product.

51 yridinium rings located at the "ends" of the cyclophane are electron-poor and prefer to enter into do

52 Cyclophanes are a venerable class of macrocyclic and cag

53 Cyclophanes are a venerable class of macrocyclic and/or

54 Tris(beta-diketimine) cyclophanes are an important ligand class for investigat

55 These types of cyclophanes are not accessible through an intramolecular

56 demonstrating that the radical states of the cyclophanes are stabilized by the radical-pairing intera

57 ]rotaxane (Cy3R), which has two wheels and a cyclophane as a blocking group.

58 ge number of potential BGCs that may use the cyclophane as a fragment.

59 on the ratio of ketene acetals to [2.2]para-cyclophanes as well as the hydrophobicity of the films.

60 distance of 3.7 A) in the adjacent parallel cyclophane, as well as (ii) between the ExBIPY(2+) unit

61 w boron-doped cyclophane, the hexabora[1(6) ]cyclophane B6-(F) Mes, in which six tricoordinate borane

62 A family of p-cyclophanes based on bis- or tetrafunctionalized 1,4-bis

63 thylene and methyl acrylate (MA) by a Pd(II) cyclophane-based alpha-diimine catalyst is reported.

64 rization, insight that can be applied beyond cyclophane-based architectures.

65 benzaldehyde and nitromethane catalyzed by a cyclophane-based bisthiourea has been studied with densi

66 ent approach via supramolecularly engineered cyclophane-based nanoenvironments that provide sufficien

67 ne, methyl acrylate, and 4-methoxystyrene in cyclophane-based Pd(II) olefin complexes by (1)H NMR and

68 ethodology to covalently link donors to form cyclophane-based thermally activated delayed fluorescenc

69 Cyclophanes bearing Me, Et, and MeO cap substituents and

70 The anthracene cyclophane bis-anthracene (BA) can undergo a [4 + 4] pho

71 um radical cation (DB(*+)) and an asymmetric cyclophane bisradical dication (DAPQT(2(*+))), affords a

72 he ubiquitous cyclobis(paraquat- p-phenylene)cyclophane ("blue box").

73 ucts (2) from which Fe3 (NH)3 L (2-1; L is a cyclophane bridged by three beta-diketiminate arms) was

74 oneered the syntheses of viologen-containing cyclophanes, but also revealed their rich redox chemistr

75 d diversity-oriented approach to macrocyclic cyclophanes by a Grignard reaction, followed by Fischer

76 the synthesis of highly charged enantiopure cyclophanes by the insertion of axially chiral enantiome

77 Three new cyclophanes (calixarene-like macrocyles 8 and 9, as well

78 Although each cyclophane can be synthesized readily without the use of

79 and found to be over 100 times slower in the cyclophane case.

80 brium studies of ethylene with nitriles, the cyclophane catalyst was found to more strongly favor the

81 nders olefin pre-equilibrium, decreasing the cyclophane catalyst's ability to preferentially incorpor

82 ich possesses the added "third dimension" of cyclophane chirality.

83 d synthesis of BlueCage(6+), a macrobicyclic cyclophane composed of six pyridinium rings fused with t

84 with MP2 computations were performed on four cyclophanes composed of two or three cyclooctatetraene (

85 ExBox(4+), a boxlike cyclophane comprising two pi-electron-poor extended viol

86 he equilibrium geometries of photoisomerized cyclophanes, concluding that D2h symmetry in the photois

87 esize, in modest yield, a nearly 2.5 nm long cyclophane consisting of 12 aromatic rings.

88 ctron-rich guests, while the "middle" of the cyclophane, consisting of the biphenylene spacer, is mor

89 Despite the fact that these cyclophanes contain a hydrophobic binding cavity of appr

90 epresents the first report of an 11-membered cyclophane containing a 1,4-disubstituted 1,2,3-triazole

91 Small cyclophanes containing aromatic groups and dialkyl ammon

92 the ring component (namely, a tetracationic cyclophane, containing two pi-electron-deficient bipyrid

93 While the cyclophane contains two reactive triple bonds, there is

94 erlocked mechanically with the tetracationic cyclophane cyclobis(paraquat-p-phenylene) (CBPQT(4+)), w

95 so-called 'blue box' (BB(4+)) tetracationic cyclophane cyclobis(paraquat-p-phenylene).

96 racterization of a substituted tetracationic cyclophane, cyclobis(paraquat-p-1,4-dimethoxyphenylene),

97 sembly in aqueous solution of the well-known cyclophane, cyclobis(paraquat-p-phenylene) (BB(4+) ), an

98 erlocked mechanically with the tetracationic cyclophane, cyclobis(paraquat-p-phenylene) (CBPQT(4+)),

99 the DNP unit is encircled by a tetracationic cyclophane, cyclobis(paraquat-p-phenylene) (CBPQT4+), co

100 The tetracationic cyclophane, cyclobis(paraquat-p-phenylene), also known a

101 n obtained on reduction of the tetracationic cyclophane, cyclobis(paraquat-p-phenylene), and the radi

102 lly designed multichromophoric tetracationic cyclophane, DAPPBox(4+), containing a diazaperopyrenium

103 formation of an asymmetric, rigid, box-like cyclophane, DAPPBox(4+).

104 ationic guests such as MV(*+) by the reduced cyclophane decreases 10-fold.

105 These redox-active cyclophanes demonstrate that geometry-matching and weak

106 cade has been used to synthesize macrocyclic cyclophane derivatives.

107 In the case of cyclophanes derived from 1,5-dinitronaphthalene, steric

108 with multiple hydrogen bonding sites to form cyclophane dimers.

109 urthermore, these highly charged enantiopure cyclophanes display CPL responses both in solution and i

110 derived guests inside the nanocavity of this cyclophane, emissive charge transfer (CT) states close t

111 Cyclophanes, especially those where pyridinium units in

112 This cyclophane, Ex(2)Box(4+), possesses the ability to form

113 Confinement of the tetracationic cyclophane (ExBox(4+) ) within a nonporous anionic polys

114 ions, is employed to synthesize a semi-rigid cyclophane (ExBox(4+)) that adopts a box-like geometry a

115 Herein, an extended viologen-based cyclophane-ExBox2(4+)-has been employed as a molecular r

116 Remarkably, these fluorescent tetracationic cyclophanes exhibit a significant AIE compared to their

117 This cyclophane exhibits three-dimensional spatial current ch

118 sides inside the cavity of the tetracationic cyclophane--exist in equilibrium in solution, has led to

119 nzymes (3-CyFEs) that catalyze three-residue cyclophane formation in the biosynthesis of a new family

120 cids can be incorporated by 3-CyFEs, and the cyclophane formation strictly occurs via a C(sp(2))-C(sp

121 The key cyclophane-forming macrocyclization reaction was accompl

122 Silver(I)-imidazole cyclophane gem-diol complex, 3 [Ag2C36 N10(O)4](2+)2(x)-

123 he acute toxicity of the ligand (imidazolium cyclophane gem-diol dichloride) was assessed by intraven

124 (2), where L(2-) is a bis(beta-diketiminate) cyclophane, gives [K(THF)(5) ][Fe(2) (CO)(2) L] (3), whi

125 ind an isomeric series of possible diradical cyclophane guests, which consist of two radical viologen

126 Reaction of a tris(beta-diketimine) cyclophane, H3L, with benzyl potassium followed by [Cu(O

127 The aromaticity in this cyclophane has been examined experimentally and theoreti

128 The strain-induced chirality of cyclophanes has attracted interest within the synthetic

129 Although a very large number cyclophanes has been reported, only a very small proport

130 ution-phase photophysical properties of this cyclophane have been investigated by both steady-state a

131 Cyclophanes have been firmly entrenched as a distinct cl

132 A new cyclophane host based on coronene bisimide is presented

133 host-guest complex based on a tetracationic cyclophane host, cyclobis(paraquat-p-phenylene) (CBPQT(4

134 as a useful building block for pi-accepting cyclophane hosts.

135 Three new azamacrocyclic-cyclophane hybrid receptors L(1), L(2), and L(3) have be

136 This Review puts the spotlight on such cyclophanes, illuminating both the chemistry that was us

137 corresponding monomeric NDI and dimeric NDI cyclophane imines.

138 -dependent chirality transfer from biaryl to cyclophane in host-guest complexes.

139 his carbazole-encapsulated biphenyl bisimide cyclophane in methylcyclohexane/carbon tetrachloride sol

140 that biosynthesizes the strained dityrosine cyclophane in the herquline A pathway was used to identi

141 to give a diversity of new thioether (hetera)cyclophanes in high yield.

142 Herein, we report on a series of cyclophanes in which the interplanar distance between tw

143 Here, we report the synthesis of a cyclophane, in which two antiaromatic porphyrin moieties

144 Peptide-derived cyclophanes inhabit a unique niche in the chemical space

145 eptor, the conversion of a hydrazine-pending cyclophane into the pseudo[1]rotaxane and, lastly, the o

146 this goal, a novel biphenyl bisimide-derived cyclophane is introduced as an electron-deficient and ef

147 he encapsulation of the second guest in this cyclophane is notably more favored than the first one.

148 The cyclophane is obtained in a three-step synthesis and can

149 rained 1,4-annulated cyclooctatetraene-based cyclophanes is described.

150 uality of AIE and CPL in these tetracationic cyclophanes is destined to be of major importance in fut

151 the reactivity of this particular family of cyclophanes is presented.

152 Association constants for the cyclophane itself, cyclophane 3, are smaller.

153 inates from the axial blocking effect of the cyclophane ligand hindering olefin substitution and equi

154 ride ligands are sterically protected by the cyclophane ligand, and these complexes selectively react

155 il the synthesis of a new C(2)-symmetric bis(cyclophane) ligand system that can be thought of as elec

156 yridyliumnaphthalene, 2, and its N,N-bridged cyclophane-like analogue, 3.

157 eterocycles via a highly strained, tricyclic-cyclophane-like palladated intermediate.

158 dination geometry relieves the strain of the cyclophane-like pre-transition state of the meta-C-H act

159 e same time, introducing a heteroatom into a cyclophane macrocycle is already known to alter all the

160 at Tyr and His can also be incorporated into cyclophane macrocycles by 3-CyFEs.

161 ogous series of 11- to 14-membered drug-like cyclophane macrocycles, representing an unusual region o

162 These strained cyclophane macrocyclic systems provide access to spatial

163 73.2% upon complexation, suggesting that the cyclophane may form an effective biaryl racemization cat

164 cal and computational analyses show that the cyclophane molecular architecture alters the conformatio

165 A novel three-dimensional (3D) cyclophane molecule 1 was synthesized and fully characte

166 lity, we have designed a bis-perylenediimide cyclophane (mPDI(2)) covalently linked to a secondary el

167 roach to a set of three inherently chiral [n]cyclophanes, [n](1,6)pyrenophanes (29a-c, n = 8-10) was

168 The terphenyl substructure of the chiral cyclophane natural product bazzanin K was constructed.

169 design and synthesis of novel planar chiral cyclophanes, obtained by ortho, ortho" anchoring of the

170 ow that self-assembled systems consisting of cyclophane octacarboxylates and a cationic surfactant ca

171 s on the potential of extended tetracationic cyclophane/perylene diimide systems as components for ar

172 lophane-[2]rotaxane (Cy2R) that has the same cyclophane pocket as Cy3R but only a single wheel.

173 -24-crown-8 (DB24C8) ether as the ring and a cyclophane pocket or an aromatic cleft as one blocking g

174 To illustrate this feature, cyclophanes possessing xylyl, alkyl, di(ethylene triamin

175 of a diverse range of structurally distinct cyclophane products.

176 f constrained guanidines termed "lockamers" (cyclophane, quinazoline, aminopyrimidazolines, aminoimid

177 additions proceeded in high yields, with the cyclophane reacting faster than its acyclic analogue.

178 d viologen units into a para-phenylene-based cyclophane results in a synthetic receptor that is ~2 nm

179 cluster supported by a tris(B-diketiminate) cyclophane results in halide loss, ligand compression, a

180 Single-crystal X-ray analyses of these [n.n]cyclophanes reveal interestingly shaped molecules with l

181 The solid-state superstructure of this cyclophane reveals a herringbone-type packing motif, lea

182 o 1,3,5-triaroylbenzene-based functionalized cyclophane ring systems has been developed.

183 decahydrofluorene core and the strained para-cyclophane ring.

184 ing in beta-hydroxylated residues within the cyclophane rings.

185 ethod for the synthesis of bis(dihydrofuryl) cyclophane scaffolds from carbonyl compounds has been de

186 The six boron atoms of the bora-cyclophane (see picture) recently reported by Chen and J

187 These novel cyclophanes share a common structural core with the pare

188 s locked in this form through an unsaturated cyclophane strap.

189 ronic landscape when incorporated within the cyclophane structure.

190 The cyclophane structures are characterized using NMR spectr

191 dextrins, cucurbiturils, and various organic cyclophanes such as calixarenes, deep cavitands, pillara

192 (4+)), a pi electron-accepting tetracationic cyclophane, synthesized by using the copper(I)-catalyzed

193 of the extended bipyridinium-based class of cyclophanes--that is, Ex(n)Box(4+) (n = 0-3), where n is

194 We introduce a new boron-doped cyclophane, the hexabora[1(6) ]cyclophane B6-(F) Mes, in

195 Cyclophane 1 is the first example of a cyclophane to act as an organocatalyst for the conversio

196 e potential, which may be the cause for this cyclophane to avoid ftf interactions.

197 osure of this unique electron-deficient bora-cyclophane to fluoride or cyanide results in amplified f

198 l of a para-xylene bridged perylene bisimide cyclophane to serve as a conceptually transferrable biar

199 cyclic voltammetry, which demonstrate these cyclophanes to be appreciably comparable to the diketoph

200 also demonstrated the ability of one of the cyclophanes to preferentially bind arginine with Ka > 11

201 lene linkers do not influence binding of the cyclophane toward small neutral guests-such as dimethoxy

202 olecular U-turn and assemble the large-sized cyclophane transition state for the remote C-H activatio

203 In each of these cyclophanes, two octaphenylnaphthalene subunits or two 1

204 e of bonding suggests the development of new cyclophane-type receptors for the recognition of anions.

205 rs governing access to tris(beta-diketimine) cyclophanes versus tripodal tri-beta-aminoenones.

206 ophane and triply [5]helicene-bridged (1,3,5)cyclophane via calculations of the magnetic response and

207 precisely probe arene-arene interactions in cyclophanes, we designed and synthesized (2,6-phenol)par

208 The cyclophanes were designed to contain a rigid, hydrophobi

209 Several novel types of cyclophanes were efficiently synthesized via an intermol

210 ith a variety of aryl dihalides, larger [n.n]cyclophanes were formed in preference to the [n]cyclopha

211 Three neutral cyclophanes were synthesized, and their association with

212 H) [where L(3-) is a tris(beta-diketiminate) cyclophane] were synthesized by treating the correspondi

213 a new design principle to achieve B/N-doped cyclophane where an electron-donor block of three triary

214 s in tandem cascading reactions within rigid cyclophanes, where reactions at a first triple bond indu

215 -p-phenylene) (CBPQT4+) pi-electron-acceptor cyclophane, which encapsulates the better pi-electron-do

216 erein, we report a neutral perylene bisimide cyclophane, which has a tailored chiral cavity with an i

217 Cyclophanes, which can be regarded as twofold or multipl

218 the femtosecond charge-transfer dynamics in cyclophanes, which consist of two precisely stacked pi-s

219 distance between the chromophores within the cyclophanes, while in the weak interaction limit, as rep

220 A tetracationic pyridinium-based cyclophane with a box-like geometry, incorporating two j

221 rides with a unique new member, a conjugated cyclophane with four anhydride groups.

222 However, the cyclophane with the four bridges in the 1, 3, 5, and 7 p

223 hese are the first reported examples of TADF cyclophanes with "electronically innocent" bridges betwe

224 The CVD co-polymerization of [2.2]para-cyclophanes with cyclic ketene acetals, specifically 5,6

225 Both COT rings in cyclophanes with two ethylene bridges (2) and with four

226 L), where L(3-) is a tris(beta-diketiminate) cyclophane, with CS(2) affords tetrathiooxalate at long

227 in which L(3-) is a tris(beta-diketiminate) cyclophane, with K(sBu)3BH afforded [Zn3(mu-H)3L] (2), a

228 tacking interaction between shape-persistent cyclophanes works cooperatively with multiple hydrogen b