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1 for SET mechanisms in the P450 oxidation of cyclopropylamines.
2 1.1]heptanes using bicyclo[1.1.0]butanes and cyclopropylamines.
3 gen abstraction at the N-H bond of secondary cyclopropylamines 1 gives a neutral aminyl radical which
4 The suicide substrate activity of N-benzyl-N-cyclopropylamine (1) and N-benzyl-N-(1'-methylcyclopropy
5 nism in the P450-catalyzed N-dealkylation of cyclopropylamines 2a and 2b, and argue strongly for the
6 ld, along with cyclopropanone hydrate (34%), cyclopropylamine (9%), benzaldehyde (6%), benzyl alcohol
8 e scaffolds to include the chlorovinyl, endo-cyclopropylamine, and hydrazine-functionalities as LSD1
11 erse array of biologically active compounds, cyclopropylamines are utilized as important synthetic in
13 will provide a foundation for the design of cyclopropylamine-based inhibitors that are selective for
15 - and trans-cyclopropanecarboxylic acids and cyclopropylamines bearing CH(2)F, CHF(2), and CF(3) subs
16 bitory scaffolds such as propargylamines and cyclopropylamines can serve as mechanism-based inactivat
17 s the discovery and biological activity of a cyclopropylamine containing inhibitor of Lysine Demethyl
18 studies should facilitate the application of cyclopropylamine-containing probes to reactions catalyze
19 racemic ring-substituted trans-2-(indol-3-yl)cyclopropylamine derivatives was synthesized and tested
20 the different methods for the preparation of cyclopropylamine derivatives, with the aim of covering t
24 e traps, N4-cyclopropylcytosine (CPC) and N2-cyclopropylamine-guanosine (CPG), incorporated in DNA du
25 echanism-based LSD1 inactivator whereas endo-cyclopropylamine-H3 does not show time-dependent inactiv
26 philic amines to yield highly valuable trans-cyclopropylamines in good yields and high diastereoselec
34 -catalyzed protocol for the monoarylation of cyclopropylamine using the sterically demanding and elec
35 e minimum onset energy of photoionization of cyclopropylamine was calculated to be 201.5 kcal/mol (CC
36 signature metabolite" for SET oxidation of a cyclopropylamine, was observed for the first time in 57%