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1  for SET mechanisms in the P450 oxidation of cyclopropylamines.
2 1.1]heptanes using bicyclo[1.1.0]butanes and cyclopropylamines.
3 gen abstraction at the N-H bond of secondary cyclopropylamines 1 gives a neutral aminyl radical which
4 The suicide substrate activity of N-benzyl-N-cyclopropylamine (1) and N-benzyl-N-(1'-methylcyclopropy
5 nism in the P450-catalyzed N-dealkylation of cyclopropylamines 2a and 2b, and argue strongly for the
6 ld, along with cyclopropanone hydrate (34%), cyclopropylamine (9%), benzaldehyde (6%), benzyl alcohol
7 n was attributable to high reactivity of the cyclopropylamine and azido moieties, respectively.
8 e scaffolds to include the chlorovinyl, endo-cyclopropylamine, and hydrazine-functionalities as LSD1
9 ate salts, boronic acids, cyclopropylarenes, cyclopropylamines, and cyclopropanols.
10                                              Cyclopropylamines are an important subclass of substitut
11 erse array of biologically active compounds, cyclopropylamines are utilized as important synthetic in
12 ethyl ketones, and accepting methylamine and cyclopropylamine as amine donor.
13  will provide a foundation for the design of cyclopropylamine-based inhibitors that are selective for
14 019 that exploit C-C single bond cleavage of cyclopropylamine-based systems.
15 - and trans-cyclopropanecarboxylic acids and cyclopropylamines bearing CH(2)F, CHF(2), and CF(3) subs
16 bitory scaffolds such as propargylamines and cyclopropylamines can serve as mechanism-based inactivat
17 s the discovery and biological activity of a cyclopropylamine containing inhibitor of Lysine Demethyl
18 studies should facilitate the application of cyclopropylamine-containing probes to reactions catalyze
19 racemic ring-substituted trans-2-(indol-3-yl)cyclopropylamine derivatives was synthesized and tested
20 the different methods for the preparation of cyclopropylamine derivatives, with the aim of covering t
21 hemically defined and densely functionalized cyclopropylamine derivatives.
22                        Unlike aziridinyl and cyclopropylamine-derivatized histone H3 peptide substrat
23            The Ti(II) -mediated formation of cyclopropylamines from alkenes and amides, the Kulinkovi
24 e traps, N4-cyclopropylcytosine (CPC) and N2-cyclopropylamine-guanosine (CPG), incorporated in DNA du
25 echanism-based LSD1 inactivator whereas endo-cyclopropylamine-H3 does not show time-dependent inactiv
26 philic amines to yield highly valuable trans-cyclopropylamines in good yields and high diastereoselec
27                                              Cyclopropylamines inactivate cytochrome P450 enzymes whi
28          In contrast, the small molecule MAO cyclopropylamine inhibitor tranylcypromine is a time-dep
29                                          The cyclopropylamine moiety therefore appears to be a good s
30 e is a time-dependent LSD1 inhibitor but exo-cyclopropylamine-peptide substrate analogue is not.
31                                              Cyclopropylamine substituted bases, N4-cyclopropylcytosi
32                                  Because the cyclopropylamine-substituted bases decompose rapidly upo
33                              In a de Meijere cyclopropylamine synthesis, a 3:1 mixture of N,N-dimethy
34 -catalyzed protocol for the monoarylation of cyclopropylamine using the sterically demanding and elec
35 e minimum onset energy of photoionization of cyclopropylamine was calculated to be 201.5 kcal/mol (CC
36 signature metabolite" for SET oxidation of a cyclopropylamine, was observed for the first time in 57%