ライフサイエンスコーパス: cyclosome

1 inhibition of the anaphase-promoting complex/cyclosome.

2 ubiquitin ligase anaphase-promoting complex/cyclosome.

3 activation of the anaphase-promoting complex/cyclosome.

4 ndependent of the anaphase-promoting complex/cyclosome.

5 C5 subunit of the anaphase promoting complex/cyclosome.

6 activation of the anaphase-promoting complex/cyclosome.

7 ll to inhibit the anaphase-promoting complex/cyclosome.

8 inhibition of the anaphase-promoting complex/cyclosome.

9 regulators by the anaphase-promoting complex/cyclosome.

10 ents of the anaphase-promoting complex (APC)/cyclosome.

11 inhibition of the anaphase-promoting complex/cyclosome.

12 t shown in other systems to regulate the APC cyclosome.

13 C2 subunit of the anaphase promoting complex/cyclosome.

14 ubiquitin to the anaphase-promoting complex/cyclosome.

15 radation by anaphase-promoting complex (APC)/cyclosome, a multisubunit ubiquitin ligase.

16 inhibitor of the anaphase-promoting complex/cyclosome, a ubiquitin ligase required for anaphase onse

17 trol is the anaphase-promoting complex (APC)/cyclosome, a ubiquitin ligase whose activation by Cdc20

18 ich Bruno and the anaphase-promoting complex/cyclosome act together to restrict the accumulation of t

19 iquitin ligase anaphase-promoting complex or cyclosome (activated by the Cdh1 adapter), and the deubi

20 ion by modulating anaphase-promoting complex/cyclosome activity, which are down-regulated rapidly aft

21 ) inhibits APC/C (anaphase-promoting complex/cyclosome) activity during S and G2 phases, and is belie

22 activation of the anaphase-promoting complex/cyclosome also requires an intact polo box.

23 uitin ligase, the anaphase-promoting complex/cyclosome, also targets cyclin B1, thereby causing inact

24 of Cdc25p by the anaphase-promoting complex/cyclosome, an E3 ubiquitin ligase.

25 The anaphase promoting complex/cyclosome and its activator Cdh1 (APC/C(Cdh1)) restrains

26 gase APC/C(Cdh1) (anaphase-promoting complex/cyclosome and its activator Cdh1).

27 The anaphase-promoting complex/cyclosome and its coactivator CDC20 (APC/C(CDC20)) form

28 APC/C(Cdc20) (the anaphase-promoting complex/cyclosome and its coactivator Cdc20, a large ubiquitin l

29 the APC/C(Cdh1) (anaphase-promoting complex/cyclosome and its coactivator Cdh1) E3 ubiquitin ligase

30 eraction with the anaphase promoting complex/cyclosome and the disposition of a putative destruction

31 tin ligase APC/C (anaphase-promoting complex/cyclosome) and its coactivator CDC20 (cell division cycl

32 inhibitor of the anaphase-promoting complex/cyclosome, and cyclin A.

33 kinase PLK1, the anaphase-promoting complex/cyclosome, and the proteasome that, when inhibited, resu

34 totic form of the anaphase-promoting complex/cyclosome (APC(Cdc20)).

35 activation of the anaphase-promoting complex/cyclosome (APC(Cdh1)) has the necessary characteristics

36 The anaphase-promoting complex or cyclosome (APC) is an unusually complicated ubiquitin li

37 substrates by the anaphase-promoting complex/cyclosome (APC) is critical for mitotic exit.

38 NG E3s, including anaphase-promoting complex/cyclosome (APC), catalyze polyubiquitination by sequenti

39 tisubunit 1.2-MDa anaphase-promoting complex/cyclosome (APC), which controls cell division by ubiquit

40 e known as the anaphase-promoting complex or cyclosome (APC/C [2]).

41 regulates the anaphase-promoting complex or cyclosome (APC/C complex) that mediates the ubiquitinati

42 by inhibiting the anaphase-promoting complex/cyclosome (APC/C(Cdc20)) [2].

43 Activation of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) by Cdc20 is delayed by the spin

44 f CDC20-activated anaphase-promoting complex/cyclosome (APC/C(CDC20)).

45 breakdown (GVBD), anaphase-promoting complex/cyclosome (APC/C) activation, and meiotic spindle assemb

46 arks of defective anaphase-promoting complex/cyclosome (APC/C) activation, including no separase acti

47 erentiation, high anaphase-promoting complex/cyclosome (APC/C) activity degrades key E2F targets to l

48 s to suppress the anaphase-promoting complex/cyclosome (APC/C) activity early in prometaphase, thereb

49 d on separase and anaphase-promoting complex/cyclosome (APC/C) activity, which also triggers the acqu

50 inhibitor of the anaphase-promoting complex/cyclosome (APC/C) after knockdown of the mitotic cyclins

51 hich inhibits the anaphase-promoting complex/cyclosome (APC/C) and blocks anaphase onset.

52 oactivator of the anaphase-promoting complex/cyclosome (APC/C) and contributes to mitotic exit and G1

53 inhibition of the anaphase-promoting complex/cyclosome (APC/C) and delayed degradation of its substra

54 ctivity of the anaphase-promoting complex or cyclosome (APC/C) and delays the onset of anaphase.

55 achine called the anaphase-promoting complex/cyclosome (APC/C) and enables the ubiquitination and deg

56 Fzr regulates the anaphase-promoting complex/cyclosome (APC/C) and is expressed at the mitotic-to-end

57 sociates with the anaphase-promoting complex/cyclosome (APC/C) and is required to activate the APC/C

58 tions between the anaphase-promoting complex/cyclosome (APC/C) and its activator subunit Cdc20 or Cdh

59 that the human E3 anaphase-promoting complex/cyclosome (APC/C) and its two partner E2s, UBE2C (aka UB

60 tosis, lacking an anaphase-promoting complex/cyclosome (APC/C) and many of the mitotic checkpoint com

61 quitylated by the anaphase-promoting complex/cyclosome (APC/C) and then subjected to proteasomal degr

62 le time after the anaphase-promoting complex/cyclosome (APC/C) becomes active, raising the question w

63 activation of the anaphase-promoting complex/cyclosome (APC/C) bound to its coactivator, Cdc20.

64 Activation of the anaphase-promoting complex/cyclosome (APC/C) by Cdc20 is critical for the metaphase

65 activation of the anaphase-promoting complex/cyclosome (APC/C) by CDC20 to CDH1 during anaphase is cr

66 ctivity of the anaphase-promoting complex or cyclosome (APC/C) by phosphorylating its activator Cdc20

67 inhibition of the anaphase-promoting complex/cyclosome (APC/C) by proTAME, which prevents binding of

68 that Arabidopsis anaphase-promoting complex/cyclosome (APC/C) coactivator genes CDC20 and CCS52B (CD

69 ial regulation of anaphase-promoting complex/cyclosome (APC/C) coactivators and its inhibitors is cru

70 in interacts with anaphase promoting complex/cyclosome (APC/C) coactivators Cdc20 and Cdh1 to mediate

71 The anaphase-promoting complex/cyclosome (APC/C) controls a variety of cellular process

72 ligase called the anaphase-promoting complex/cyclosome (APC/C) controls mitotic exit.

73 y proteins by the anaphase-promoting complex/cyclosome (APC/C) controls sister chromatid segregation,

74 The anaphase-promoting complex/cyclosome (APC/C) controls the onset of anaphase by targ

75 The anaphase promoting complex/cyclosome (APC/C) controls unidirectional progression th

76 estruction by the anaphase promoting complex/cyclosome (APC/C) during meiosis I (MI) exit.

77 (DIA) data of the anaphase promoting complex/cyclosome (APC/C) during mitosis.

78 ovel role for the anaphase-promoting complex/cyclosome (APC/C) during this process.

79 The anaphase promoting complex/cyclosome (APC/C) E3 ligase controls mitosis and nonmito

80 The anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase functions with the

81 activator of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase.

82 substrates by the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase.

83 G(1) phase by the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase.

84 activation of the anaphase-promoting complex/cyclosome (APC/C) E3 ubiquitin ligase.

85 mutants in the anaphase-promoting complex or cyclosome (APC/C) exhibit defects in germline proliferat

86 A and B-restrain anaphase-promoting complex/cyclosome (APC/C) function, whereas the late-destroyed c

87 g connection: the Anaphase Promoting Complex/Cyclosome (APC/C) has a second function in controlling l

88 onstrate that the anaphase-promoting complex/cyclosome (APC/C) in complex with Cdh1 has an unexpected

89 activation of the anaphase-promoting complex/cyclosome (APC/C) in interphase, resulting in failure of

90 activation of the anaphase-promoting complex/cyclosome (APC/C) in mitosis.

91 are essential for anaphase promoting complex/cyclosome (APC/C) inhibition.

92 cumulation of the anaphase-promoting complex/cyclosome (APC/C) inhibitor Emi1 and the concomitant blo

93 The anaphase-promoting complex/cyclosome (APC/C) inhibitor Emi1 controls progression to

94 Expression of the anaphase-promoting complex/cyclosome (APC/C) inhibitor Emi1 is required for the acc

95 The anaphase promoting complex/cyclosome (APC/C) inhibitor Emi2 is another recent focus

96 Emi2, the meiotic anaphase-promoting complex/cyclosome (APC/C) inhibitor.

97 The anaphase-promoting complex/cyclosome (APC/C) is a cell cycle-regulated E3 ubiquitin

98 The anaphase-promoting complex/cyclosome (APC/C) is a conserved multisubunit E3 ubiquit

99 The anaphase-promoting complex/cyclosome (APC/C) is a conserved multisubunit ubiquitin

100 The anaphase-promoting complex/cyclosome (APC/C) is a conserved ubiquitin ligase that h

101 The anaphase-promoting complex or cyclosome (APC/C) is a conserved, multisubunit E3 ubiqui

102 The anaphase-promoting complex or cyclosome (APC/C) is a large E3 RING-cullin ubiquitin li

103 The anaphase promoting complex/cyclosome (APC/C) is a large multi-subunit E3 ubiquitin

104 The anaphase-promoting complex/cyclosome (APC/C) is a large multimeric cullin-RING E3 u

105 The anaphase-promoting complex/cyclosome (APC/C) is a large multiprotein E3 ubiquitin l

106 The anaphase-promoting complex/cyclosome (APC/C) is a large multisubunit complex that r

107 The anaphase-promoting complex/cyclosome (APC/C) is a large, multisubunit ubiquitin lig

108 The anaphase-promoting complex/cyclosome (APC/C) is a massive E3 ligase that controls m

109 The anaphase-promoting complex/cyclosome (APC/C) is a member of the RING family of E3 u

110 The anaphase-promoting complex/cyclosome (APC/C) is a multicomponent E3 ubiquitin ligas

111 The anaphase-promoting complex or cyclosome (APC/C) is a multiprotein subunit E3 ubiquitin

112 The anaphase-promoting complex/cyclosome (APC/C) is a protein-ubiquitin ligase (E3) tha

113 The anaphase-promoting complex or cyclosome (APC/C) is a ubiquitin ligase essential for th

114 The anaphase-promoting complex or cyclosome (APC/C) is a ubiquitin ligase that polyubiquit

115 The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase and critical

116 The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase composed of

117 The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase in the ubiqu

118 The anaphase-promoting complex/cyclosome (APC/C) is an E3 ubiquitin ligase mediating ta

119 The Anaphase-Promoting Complex/Cyclosome (APC/C) is an E3 ubiquitin ligase, well known

120 The Anaphase-Promoting Complex/Cyclosome (APC/C) is an essential ubiquitin ligase that

121 The anaphase-promoting complex/cyclosome (APC/C) is an essential ubiquitin ligase that

122 The anaphase-promoting complex/cyclosome (APC/C) is an evolutionarily conserved ubiquit

123 The anaphase-promoting complex/cyclosome (APC/C) is an ubiquitin ligase that functions

124 The anaphase-promoting complex or cyclosome (APC/C) is an unusually large E3 ubiquitin lig

125 Anaphase promoting complex/cyclosome (APC/C) is reported to play an important role

126 inhibition of the anaphase-promoting complex/cyclosome (APC/C) is responsible for this arrest.

127 The anaphase-promoting complex/cyclosome (APC/C) is the E3 ubiquitin ligase that, toget

128 The anaphase-promoting complex/cyclosome (APC/C) is the ubiquitin ligase essential to m

129 The anaphase-promoting complex or cyclosome (APC/C) is the ubiquitin ligase that regulates

130 on of cyclin B by anaphase-promoting complex/cyclosome (APC/C) is, in part, due to elevated levels of

131 The anaphase promoting complex/cyclosome (APC/C) mediates the metaphase-to-anaphase tra

132 The anaphase-promoting complex/cyclosome (APC/C) orchestrates cell cycle progression by

133 The anaphase-promoting complex/cyclosome (APC/C) promotes anaphase onset and mitotic ex

134 For example, the anaphase-promoting complex/cyclosome (APC/C) promotes the exit from mitosis via des

135 The anaphase-promoting complex/cyclosome (APC/C) regulates multiple stages of the cell

136 The anaphase-promoting complex/cyclosome (APC/C) regulates sister chromatid segregation

137 CDKs and the anaphase promoting complex/cyclosome (APC/C) restrict licensing to G1 phase by dire

138 similar to known Anaphase-Promoting Complex/Cyclosome (APC/C) substrates to identify additional puta

139 t times after the anaphase-promoting complex/cyclosome (APC/C) switches from binding Cdc20 to Cdh1.

140 uitin ligase, the anaphase-promoting complex/cyclosome (APC/C) targets Ams2 for destruction in G(1).

141 tween pRB and the anaphase-promoting complex/cyclosome (APC/C) that controls p27(Kip1) stability by t

142 ich activates the anaphase-promoting complex/cyclosome (APC/C) that triggers anaphase and mitotic exi

143 activation of the anaphase-promoting complex/cyclosome (APC/C) throughout the spindle and the cytopla

144 ter activates the anaphase-promoting complex/cyclosome (APC/C) to destroy cyclins.

145 twork anchors the anaphase-promoting complex/cyclosome (APC/C) to the mitotic spindle and poles.

146 cycles by the anaphase-promoting complex or cyclosome (APC/C) ubiquitin ligase depends on its coacti

147 SAC prevents the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase from recognizing cycl

148 a cofactor of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase in neurons [Cdh1 cond

149 The anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase is known to target th

150 The anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase is tightly regulated

151 ike kinase 1, the anaphase promoting complex/cyclosome (APC/C) ubiquitin ligase plays an essential ro

152 ked to the active anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase, suggesting that pRB-

153 ystem acts on the Anaphase-Promoting Complex/Cyclosome (APC/C) ubiquitin ligase, which targets for de

154 s mediated by the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase.

155 activator of the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase.

156 that inhibits the Anaphase Promoting Complex/Cyclosome (APC/C) ubiquitin ligase.

157 substrates by the anaphase-promoting complex/cyclosome (APC/C) ubiquitin-protein ligase.

158 ed, the E3 ligase anaphase promoting complex/cyclosome (APC/C) ubiquitylates securin for proteolysis,

159 and inhibits the anaphase-promoting complex/cyclosome (APC/C) until all chromosomes are properly att

160 inactivating the anaphase promoting complex/cyclosome (APC/C) until all chromosomes are properly att

161 MCC inhibits the anaphase-promoting complex/cyclosome (APC/C) until the checkpoint is satisfied.

162 ed binding of the anaphase-promoting complex/cyclosome (APC/C) with its activator Cdc20, and the dela

163 interact with the anaphase promoting complex/cyclosome (APC/C)(Cdc20) and to displace the BubR1 SAC c

164 An example is the anaphase-promoting complex/cyclosome (APC/C), a 13-subunit ubiquitin ligase that in

165 y activity of the Anaphase Promoting Complex/Cyclosome (APC/C), a multisubunit E3 ubiquitin ligase ta

166 The anaphase-promoting complex or cyclosome (APC/C), a multisubunit E3 ubiquitin ligase, i

167 activators of the anaphase-promoting complex/cyclosome (APC/C), a multisubunit E3 ubiquitin ligase.

168 ive regulators of anaphase-promoting complex/cyclosome (APC/C), a multisubunit ubiquitin E3 ligase th

169 controlled by the Anaphase Promoting Complex/Cyclosome (APC/C), a specific E3 ubiquitin ligase that i

170 substrates of the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase essential for mito

171 d in vivo, on the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that controls mito

172 substrate of the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that controls mito

173 s strategy to the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that controls sist

174 MCC inhibits the anaphase-promoting complex/cyclosome (APC/C), a ubiquitin ligase that targets for d

175 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C), accumulates on DNA breaks in a BubR1

176 The anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase responsible fo

177 we show that the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase, regulates the

178 activator of the Anaphase Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase.

179 e activity of the Anaphase-Promoting Complex/Cyclosome (APC/C), an E3 ubiquitin ligase.

180 The anaphase-promoting complex/cyclosome (APC/C), an essential ubiquitin protein ligase

181 , inhibits the anaphase-promoting complex or cyclosome (APC/C), and delays anaphase onset to prevent

182 , inhibits the anaphase-promoting complex or cyclosome (APC/C), and prevents premature sister chromat

183 e, known as Cdc20-anaphase promoting complex/cyclosome (APC/C), and stabilizes securin and cyclin to

184 s, to inhibit the anaphase-promoting complex/cyclosome (APC/C), and to delay anaphase onset.

185 substrates of the anaphase-promoting complex/cyclosome (APC/C), by APC/C coactivators and indicate a

186 activators of the anaphase-promoting complex/cyclosome (APC/C), Cdc20 and Cdh1, facilitate ubiquitina

187 component of the anaphase-promoting complex/cyclosome (APC/C), in all affected individuals, either i

188 regulator, the anaphase-promoting complex or cyclosome (APC/C), in the regulation of cell fate throug

189 The anaphase-promoting complex, or cyclosome (APC/C), is a large E3 ubiquitin ligase compos

190 The anaphase-promoting complex, or cyclosome (APC/C), is a ubiquitin ligase that selectivel

191 transitions, the anaphase-promoting complex/cyclosome (APC/C), is an E3 ubiquitin ligase.

192 uitin ligase, the anaphase-promoting complex/cyclosome (APC/C), promotes exit from mitosis by directi

193 activator of the anaphase-promoting complex/cyclosome (APC/C), promotes Smk1 activation during meios

194 uitin ligase, the anaphase-promoting complex/cyclosome (APC/C), regulates critical cellular processes

195 ulatory E3, human anaphase-promoting complex/cyclosome (APC/C), relies on UBE2C to prime substrates w

196 C1 subunit of the anaphase-promoting complex/cyclosome (APC/C), resulting in G(2)/M cell cycle arrest

197 inhibitors of the anaphase-promoting complex/cyclosome (APC/C), such as the early mitotic inhibitor 1

198 and inhibits the anaphase-promoting complex/cyclosome (APC/C), the E3 ubiquitin ligase that initiate

199 activator of the anaphase-promoting complex/cyclosome (APC/C), the E3 ubiquitin ligase whose activit

200 d inhibits the anaphase-promoting complex or cyclosome (APC/C), thus ensuring accurate chromosome seg

201 ctivity of the anaphase-promoting complex or cyclosome (APC/C), thus preventing precocious chromosome

202 he Cdc20-bound anaphase-promoting complex or cyclosome (APC/C), to delay anaphase, thereby preventing

203 s mediated by the anaphase-promoting complex/cyclosome (APC/C), whereas degradation of TbCPC1 and TbC

204 l cycle E3 ligase anaphase-promoting complex/cyclosome (APC/C), which also controls E2F7 and E2F8.

205 1.2-MDa E3 ligase anaphase-promoting complex/cyclosome (APC/C), which controls cell division and many

206 sms including the anaphase-promoting complex/cyclosome (APC/C), which is the largest known E3 ubiquit

207 3) subunit of the anaphase promoting complex/cyclosome (APC/C), which results in the polyubiquitinati

208 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C), which, together with its substrate ad

209 ubiquitin ligase anaphase promoting complex/cyclosome (APC/C), whose action is necessary for anaphas

210 uitylation by the anaphase-promoting complex/cyclosome (APC/C)-cadherin 1 (Cdh1), an E3 ubiquitin lig

211 ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C)-Cdc20 that triggers the metaphase-anap

212 lts indicate that anaphase-promoting complex/cyclosome (APC/C)-Cdh1 specifically targets EYA1 for deg

213 is degraded in an anaphase-promoting complex/cyclosome (APC/C)-dependent manner.

214 oint prevents the anaphase-promoting complex/cyclosome (APC/C)-mediated degradation of cyclin B and s

215 GPC1 inhibits the anaphase-promoting complex/cyclosome (APC/C)-mediated degradation of mitotic cyclin

216 atic cells, where anaphase-promoting complex/cyclosome (APC/C)-mediated proteasomal destruction remov

217 e is regulated by anaphase-promoting complex/cyclosome (APC/C)-mediated protein degradation.

218 l attachment with anaphase-promoting complex/cyclosome (APC/C)-mediated securin and cyclin B1 destruc

219 s mediated by the anaphase-promoting complex/cyclosome (APC/C)-targeted ubiquitination and proteolysi

220 of the E3 ligase anaphase promoting complex/cyclosome (APC/C).

221 rved regulator of anaphase promoting complex/cyclosome (APC/C).

222 ssociation of the anaphase-promoting complex/cyclosome (APC/C).

223 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C).

224 ubiquitin ligase anaphase-promoting complex/cyclosome (APC/C).

225 ubunits of the anaphase-promoting complex or cyclosome (APC/C).

226 activator of the anaphase-promoting complex/cyclosome (APC/C).

227 uitination by the Anaphase-Promoting Complex/Cyclosome (APC/C).

228 ry subunit of the anaphase-promoting complex/cyclosome (APC/C).

229 on depends on the anaphase-promoting complex/cyclosome (APC/C).

230 regulator of the Anaphase-Promoting Complex/Cyclosome (APC/C).

231 st subunit of the anaphase-promoting complex/cyclosome (APC/C).

232 on through the anaphase promoting complex or cyclosome (APC/C).

233 activation of the anaphase-promoting complex/cyclosome (APC/C).

234 ociation with the anaphase promoting complex/cyclosome (APC/C).

235 d inhibits the anaphase-promoting complex or cyclosome (APC/C).

236 activation of the anaphase-promoting complex/cyclosome (APC/C).

237 es (CDKs) and the anaphase promoting complex/cyclosome (APC/C).

238 a subunit of the anaphase-promoting complex/cyclosome (APC/C).

239 mponent of the anaphase-promoting complex or cyclosome (APC/C).

240 of Mad2 with the anaphase promoting complex/cyclosome (APC/C).

241 latory component, anaphase-promoting complex/cyclosome (APC/C).

242 ubunits of the anaphase-promoting complex or cyclosome (APC/C).

243 hich inhibits the anaphase-promoting complex/cyclosome (APC/C).

244 activator of the anaphase-promoting complex/cyclosome (APC/C).

245 to inactivate the Anaphase Promoting Complex/Cyclosome (APC/C).

246 activator of the anaphase-promoting complex/cyclosome (APC/C).

247 c activity of the anaphase-promoting complex/cyclosome (APC/C).

248 receptors for the Anaphase Promoting Complex/Cyclosome (APC/C).

249 components of the anaphase-promoting complex/cyclosome (APC/C).

250 ubiquitin ligase anaphase promoting complex/cyclosome (APC/C).

251 ubiquitin ligase Anaphase-Promoting Complex/Cyclosome (APC/C).

252 x) and the APC/C (anaphase promoting complex/cyclosome), are vital in ensuring the temporal order of

253 , an inhibitor of anaphase-promoting complex/cyclosome, are elevated in Plk1-depleted cells.

254 meiotic division, anaphase-promoting complex/cyclosome associated with Cdc20 (APC/C(Cdc20)) activates

255 h inhibits the anaphase-promoting complex or cyclosome bound to Cdc20 (APC/C(Cdc20)) to delay anaphas

256 ediated by the anaphase-promoting complex or cyclosome bound to Cdh1 (APC/C(Cdh1)), resulting in accu

257 inhibitor of the anaphase-promoting complex/cyclosome bound to its specificity factor, Cdc20.

258 cyclin B1 by the anaphase-promoting complex/cyclosome, but some cells evade this checkpoint and slip

259 inhibition of the anaphase-promoting complex/cyclosome by a kinetochore-derived "wait anaphase" signa

260 tion inhibits the anaphase-promoting complex/cyclosome (Cdc20-APC/C), thereby preventing the proteoly

261 le is achieved by anaphase-promoting complex/cyclosome(Cdh1) (APC/C(Cdh1)), a multisubunit E3 ubiquit

262 e degraded by the anaphase-promoting complex/cyclosome-CDH1 E3 ligase complex.

263 Anaphase-promoting complex/cyclosome-CDH1 target proteins generally have D-Box or K

264 cell cycle in an anaphase-promoting complex/cyclosome-CDH1-dependent manner.

265 1 also binds with anaphase-promoting complex/cyclosome co-activators Cdc20 and Cdh1.

266 nant forms of the anaphase-promoting complex/cyclosome, cohesin, and kinetochore complexes.

267 by the proteasome via the anaphase-promoting cyclosome complex (APC/c) pathway.

268 st targets of the anaphase-promoting complex/cyclosome complex, a set of genes whose expression is pr

269 ox-containing and anaphase-promoting complex/cyclosome complexes.

270 t with a small molecule inhibitor of the APC/cyclosome could sensitize otherwise paclitaxel-resistant

271 inding of CDH1 to anaphase promoting complex/cyclosome decreased, resulting in an attenuation of anap

272 aded in an APC/C (anaphase-promoting complex/cyclosome)-dependent manner.

273 on of separase by anaphase-promoting complex/cyclosome-dependent degradation of cyclin B1.

274 onstrate that the Anaphase-Promoting Complex/Cyclosome directly engages the acidic patch, and we eluc

275 binding with the anaphase-promoting complex/cyclosome E3 ubiquitin ligase component APC-2 protein.

276 trate that APC/C (anaphase-promoting complex/cyclosome) enzyme is active in ES cells but attenuated b

277 e complex; APC/C (anaphase promoting complex/cyclosome) facilitates the cell cycle stage-specific deg

278 mained active and anaphase-promoting complex/cyclosome function was inhibited.

279 c20 activates the anaphase-promoting complex/cyclosome in a substrate-specific manner.

280 inhibition of the anaphase-promoting complex/cyclosome, in part by a newly identified protein, Emi2 (

281 Cdc20 binding and anaphase-promoting complex/cyclosome inhibition: a destruction box (D box) and a ph

282 The anaphase-promoting complex (APC) or cyclosome is a multisubunit ubiquitin-protein ligase tha

283 ortex form of the Anaphase Promoting Complex/Cyclosome is inactive.

284 demonstrates that anaphase promoting complex/cyclosome is required not only in proliferating cells bu

285 ation of the anaphase-promoting complex (APC/cyclosome) is involved in the TGF-beta signaling pathway

286 The anaphase-promoting complex (APC), or cyclosome, is an E3 ubiquitin-protein ligase that collab

287 activator of the anaphase-promoting complex/cyclosome, is excluded from interphase nuclei, but enter

288 bination with the anaphase-promoting complex/cyclosome mutation bimE7.

289 vity of the anaphase-promoting complex (APC)/cyclosome needs to be tightly regulated for proper cell

290 -promoting complex (APC/C, also known as the cyclosome) regulates the ubiquitin-dependent proteolysis

291 a-solenoid folds composed of 9-11 proteasome/cyclosome repeats, each approximately 40 residues long a

292 protein sequences containing the proteasome/cyclosome repeats.

293 activator of the anaphase-promoting complex/cyclosome that initiates anaphase onset by ordering the

294 ng subunit of the anaphase-promoting complex/cyclosome that regulates multiple steps in meiotic devel

295 ely activation of anaphase-promoting complex/cyclosome to allow meiosis I exit and for the rapid rise

296 by activating the anaphase-promoting complex/cyclosome to initiate the ubiquitination and subsequent

297 tin ligase APC/C (Anaphase-Promoting Complex/Cyclosome) to degrade inhibitors of anaphase initiation.

298 t Cdc20, of APC (anaphase-promoting complex)/cyclosome ubiquitin ligase reduced the level of Dnmt1 in

299 uitination by the anaphase-promoting complex/cyclosome ubiquitin ligase, acting in conjunction with t

300 to inhibit the anaphase-promoting complex or cyclosome until all chromosomes achieve bipolar microtub