ライフサイエンスコーパス: cyst fluid

1 NF-alpha accumulates to high levels in ADPKD cyst fluid.

2 rent compounds were identified in plasma and cyst fluid.

3 has been isolated and identified within the cyst fluid.

4 growth factors present in human ADPKD liver cyst fluid.

5 could be identified in the patients' ovarian cyst fluids.

6 issues as well as in premalignant pancreatic cyst fluids.

7 e of radiographic septations or preoperative cyst fluid analysis (carcinoembryonic antigen, amylase,

8 imaging includes endoscopic ultrasound with cyst fluid analysis and cytology to confirm the type of

9 lastic pancreatic cysts; however, a detailed cyst fluid analysis for protein and genetic markers may

10 radiographic studies, endoscopic evaluation, cyst fluid analysis, and novel molecular diagnostics, ma

11 or were monitored with endoscopic US-guided cyst fluid analysis, cytologic analysis, and follow-up i

12 patic CCAs, as well as in matched pancreatic cyst fluid and bile duct brushings.

13 ry IOPNs, as well as in PDACs and pancreatic cyst fluid and bile duct cells from the same patients.

14 was performed of MCP-1 in urine, serum, and cyst fluid and MCP-1 production by mural epithelial cell

15 were performed on peri-operative pancreatic cyst fluid and pre-operative plasma from IPMN and serous

16 We purified human ZAG from breast cyst fluid and serum and produced a panel of anti-ZAG mo

17 Protein profiles of cyst fluid and serum were similar.

18 eomic profiling was performed on peritumoral cyst fluid and serum.

19 The presence of IL13 in cyst fluid and the overexpression of IL4/13 receptor cha

20 egulator (CFTR) participates in secretion of cyst fluid, and the mammalian target of rapamycin (mTOR)

21 Cyst fluid AREG levels are significantly higher in cance

22 The cellular content of pancreatic cyst fluid aspirate is often suboptimal for analysis, bu

23 ry or endoscopic ultrasonography (US)-guided cyst fluid aspiration and biopsy were included.

24 ade, and gliomatosis peritonei, but not with cyst fluid aspiration/spillage, tumor enucleation, nodal

25 ility of amphiregulin (AREG) as a pancreatic cyst fluid biomarker to differentiate non-mucinous, beni

26 tic modalities such as cytology, biopsy, and cyst fluid biomarkers allow for definitive diagnosis of

27 ted mass spectrometry analysis of just three cyst fluid biomarkers provides highly accurate identific

28 cyst walls are responsible for secreting the cyst fluid, but the mechanism through which this secreti

29 d that ATP is released in vitro and into the cyst fluid by cystic epithelial cells in concentrations

30 study to evaluate AREG levels in pancreatic cyst fluid by ELISA from 33 patients with a histological

31 ecificity, and when used in combination with cyst fluid CA 19-9 gave a sensitivity of 87% at 86% spec

32 abolomic and lipidomic analysis of plasma or cyst fluid can improve discrimination of IPMN from SCN a

33 These biomarkers performed better than cyst fluid carcinoembryonic antigen (37%/80% sensitivity

34 ably with the accuracy of standard analyses: cyst fluid carcinoembryonic antigen (61%; 95% CI, 46% to

35 Although cyst fluid carcinoembryonic antigen is a very good marke

36 Biliary cyst fluid caused a dose-dependent induction of eNOS mes

37 lysis of the tumor markers demonstrated that cyst fluid CEA (optimal cutoff of 192 ng/mL) demonstrate

38 Of tested markers, cyst fluid CEA is the most accurate test available for t

39 These results show that bile and biliary cyst fluid contain high concentrations of ET-1 that are

40 Control bile and biliary cyst fluid contained concentrations of ET-1 25- to 42-fo

41 A subset of cyst fluids contained as much as 0.5 to 10 microM ATP, d

42 The results of EUS imaging, cyst fluid cytology, and cyst fluid tumor markers (CEA,

43 osorbent assay analysis of human ADPKD liver cyst fluid detected epithelial neutrophil attractant 78,

44 be induced by TNF-alpha, which is present in cyst fluid during cyst development.

45 und-guided fine-needle aspiration pancreatic cyst fluid from 31 institutions.

46 sorbent assay (ELISA) analyses of tissue and cyst fluid from pancreatic intraductal papillary mucinou

47 Cyst fluid from patients with SCA (n = 15), non main-duc

48 thermore, we found that EPO is detectable in cyst fluid from S-HB (n = 14), while absent in CSF (n =

49 In a search for modulators of cAMP synthesis cyst fluids from 18 patients with autosomal dominant or

50 "Flash-frozen" cyst fluids from ADPKD cysts, harvested from multiple do

51 DNA mutations and proteins within pancreatic cyst fluid have identified potential biomarkers to aid w

52 echanisms by which SMYD2 might be induced by cyst fluid IL-6 and TNF-alpha in ADPKD kidneys.

53 Biliary cyst fluid increases eNOS expression and activity in an

54 87 different cyst fluid proteins, including cyst fluid inflammatory markers (CFIMs), as possible sur

55 xt-generation sequencing (NGS) of pancreatic cyst fluid is a useful adjunct in the assessment of pati

56 We have shown previously shown that IL13 in cyst fluid leads to aberrant activation of STAT6 via the

57 sults suggest that the genetic evaluation of cyst fluids might be able to inform the management of th

58 Cyst fluid mucin glycoproteins and cytokines may identif

59 Samples of pancreatic cyst fluid (n = 5, collected before surgery) and bile du

60 utions in advanced diagnostic tools, such as cyst fluid next-generation sequencing and EUS-guided con

61 Cyst fluid NGS is highly sensitive and specific for pred

62 higher than in serum or urine were found in cyst fluids obtained from nephrectomy specimens (range,

63 Hp concentration in ovarian cyst fluid (OCF) can be detected and quantified using Ra

64 -deficient murine kidneys and accumulated in cyst fluid of human ADPKD kidneys.

65 proteins significantly overexpressed in the cyst fluid of patients with mucinous cysts were CEA (med

66 In contrast, no mutations were found in the cyst fluids of 18 patients with benign tumors or non-neo

67 or-specific mutations were detectable in the cyst fluids of 19 of 23 (83%) borderline tumors, 10 of 1

68 In this study differential cyst fluid protein expression was observed between SCA a

69 assay was performed to evaluate 87 different cyst fluid proteins, including cyst fluid inflammatory m

70 ycosylation variants on specific proteins in cyst fluid samples could serve as biomarkers to aid in t

71 Methods Cyst fluid samples obtained by routine endoscopic ultras

72 We obtained cyst fluid samples of 169 PCLs (90 intraductal papillary

73 All five cyst fluid samples were negative.

74 Fifty-three cyst fluid samples were obtained from patients with muci

75 tal papillary mucinous neoplasms (IPMNs), 55 cyst fluid samples, 104 pancreatic ductal adenocarcinoma

76 Among the cyst fluid samples, the median (IQR) AREG levels for non

77 oteins implicated in pancreatic neoplasia in cyst fluid samples.

78 Das-1 was performed in parallel using banked cyst fluid samples.

79 TICIPANTS: For this cohort study, pancreatic cyst fluid specimens from 31 medical centers were sent t

80 gy of an Smac-mimetic and TNF-alpha in renal cyst fluid, that attenuates cyst development, providing

81 lts of EUS imaging, cyst fluid cytology, and cyst fluid tumor markers (CEA, CA 72-4, CA 125, CA 19-9,

82 Mean cyst fluid vascular endothelial growth factor concentrat

83 te detrimentally to the gradual expansion of cyst fluid volume that is a hallmark of ADPKD.

84 f the sodium/potassium (Na+/K+) ratio in the cyst fluid was less than 3, or type II if the Na+/K+ rat

85 End-stage ADPKD renal tissue extracts and cyst fluids were assayed for time-dependent, chymostatin

86 ted proteins are also detected in pancreatic cyst fluids, which allows us to link proteins and glycop