ライフサイエンスコーパス: cystathionine gamma-lyase

1 s of peptidases, glutamate dehydrogenase and cystathionine gamma-lyase.

2 ps involving cystathionine beta-synthase and cystathionine gamma-lyase.

3 ion of either cystathionine beta-synthase or cystathionine gamma-lyase.

4 ation with a cystathionine-beta-synthase and cystathionine-gamma-lyase.

5 RNA levels of cystathionase (cystathionine gamma-lyase), a key enzyme in the synthesi

6 ely, silencing of the H(2)S-producing enzyme cystathionine-gamma-lyase abolishes NO-stimulated cGMP a

7 uation, immunohistochemistry (nitrotyrosine, cystathionine gamma-lyase, activated caspase-3, and extr

8 atio and lower cystathione beta-synthase and cystathionine gamma-lyase activity.

9 H(2)S by cardiac-specific overexpression of cystathionine gamma-lyase (alpha-MHC-CGL-Tg mouse) signi

10 Cardiomyocyte-specific overexpression of cystathionine gamma-lyase (an enzyme that produces H(2)S

11 ls to make H(2)S via increased expression of cystathionine gamma-lyase and cystathionine beta-synthas

12 responsible for endogenous H2 S production, cystathionine-gamma-lyase and 3-mercaptopyruvate sulphur

13 bited transcriptional activation of Bhmt and cystathionine gamma-lyase by FOXA1.

14 s the transcriptional activation of Bhmt and cystathionine gamma-lyase by FOXA1.

15 Inhibition of cystathionine gamma-lyase causes rapid necrosis of TR/GR

16 cysteine, alpha-ketobutyrate and ammonia by cystathionine gamma-lyase (CGL) in the reverse transsulf

17 of the transsulfuration pathway (TSP) enzyme cystathionine gamma-lyase (CGL), resulting in increased

18 onia and alpha-ketobutyrate by the action of cystathionine gamma-lyase (CGL).

19 nzymes cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CGL).

20 the key enzyme required for this conversion, cystathionine gamma-lyase (CGL).

21 Human cystathionine-gamma-lyase (CGL) is a pyridoxal-5'-phosph

22 , namely, cystathionine beta-synthase (CBS), cystathionine gamma lyase (CSE) and 3-mercaptopyruvate s

23 ine by cystathionine beta synthase (CBS) and cystathionine gamma lyase (CSE) enzymes.

24 However, whether cystathionine gamma lyase (CSE), a dominant H(2) S gener

25 ndothelial cells, cysteine metabolism by the cystathionine gamma lyase (CSE), generates hydrogen sulf

26 omparing wild type mice to mice deficient in cystathionine gamma-lyase (CSE(-/-)), a major endogenous

27 rived vasodilator, is produced by the enzyme cystathionine gamma-lyase (CSE) and acts by hyperpolariz

28 Cystathionine gamma-lyase (CSE) and cystathionine beta-s

29 rates, cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE) are enzymes that catalys

30 on and activity of the H2S-generating enzyme cystathionine gamma-lyase (CSE) by promoting its transla

31 Cystathionine gamma-lyase (CSE) catalyzes H(2)S synthesi

32 ect enzymatically produced H2S from isolated cystathionine gamma-lyase (CSE) enzymes (p < 0.001) and

33 d that mice lacking the H2S-producing enzyme cystathionine gamma-lyase (CSE) exhibit elevated oxidati

34 of hydrogen sulfide (H(2)S) by inhibition of cystathionine gamma-lyase (CSE) increases sFlt-1 and sol

35 Cystathionine gamma-lyase (CSE) is a major H(2)S-produci

36 Cystathionine gamma-lyase (CSE) is one of the major enzy

37 Cystathionine gamma-lyase (CSE) produces H2S via enzymat

38 Cystathionine gamma-lyase (CSE) produces hydrogen sulfid

39 SREBP-1c reduced cystathionine gamma-lyase (CSE) via miR-216a, which in t

40 Cystathionine gamma-lyase (CSE), 1 of 3 hydrogen-sulfide

41 The expression of cystathionine gamma-lyase (CSE), a major H(2)S producing

42 Both H2S production and cystathionine gamma-lyase (CSE), an H2S enzyme, levels w

43 e of O2 sensing in the carotid body, express cystathionine gamma-lyase (CSE), an H2S-generating enzym

44 thway, cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE), are believed to be chie

45 since mice lacking its biosynthetic enzyme, cystathionine gamma-lyase (CSE), display pronounced hype

46 thway, cystathionine beta-synthase (CBS) and cystathionine gamma-lyase (CSE), H2S has been implicated

47 H2S), a gaseous messenger produced mainly by cystathionine gamma-lyase (CSE), is a proangiogenic vaso

48 Here we show a major depletion of cystathionine gamma-lyase (CSE), the biosynthetic enzyme

49 Experiments with several blockers of cystathionine gamma-lyase (CSE), the enzyme responsible

50 Cystathionine gamma-lyase (CSE), the enzyme responsible

51 ne K(M) and V(max) for natural substrates of cystathionine gamma-lyase (CSE), the main enzyme respons

52 rom ischemia/reperfusion injury, but whether cystathionine gamma-lyase (CSE), which produces endogeno

53 Using cystathionine gamma-lyase (CSE)-deficient mice, we demon

54 treatment with Na2S or by overexpression of cystathionine gamma-lyase (CSE).

55 activity of cystathionine beta-synthase and cystathionine gamma-lyase (CSE).

56 of the trans-sulfuration pathway, including cystathionine gamma-lyase (CSE).

57 d by hydrogen sulfide (H(2)S) synthesized by cystathionine gamma-lyase (CSE).

58 way enzymes, cystathionine beta-synthase and cystathionine gamma-lyase (CSE).

59 Cystathionine gamma-lyase (CSE; also cystathionase), a p

60 1,25(OH)(2)D(3) also caused cystathionine-gamma-lyase (CSE) activation and H(2)S for

61 sent study aimed to identify the presence of cystathionine-gamma-lyase (CSE) and 3-mercaptopyruvate s

62 Inhibition of both cystathionine-gamma-lyase (CSE) and cystathionine-beta-s

63 overexpression of the H(2)S-producing enzyme cystathionine-gamma-lyase (CSE) attenuated the hyperglyc

64 e in vascular beds, and its synthetic enzyme cystathionine-gamma-lyase (CSE) is down-regulated in gro

65 Cystathionine-gamma-lyase (CSE) is the predominant endot

66 etic ablation of the H2S-synthesizing enzyme cystathionine-gamma-lyase (CSE) normalized breathing in

67 The H2S-producing enzyme cystathionine-gamma-lyase (CSE) was expressed in both ne

68 7 and propargylglycin (PAG), an inhibitor of cystathionine-gamma-lyase (CSE), a key enzyme that produ

69 of the CO-regulated H(2)S producing enzyme, cystathionine-gamma-lyase (CSE), reduced transmission fa

70 hydrogen sulphide (H2S)-synthesizing enzyme cystathionine-gamma-lyase (CSE).

71 abolism: cystathionine-ss-synthase (CBS) and cystathionine-gamma-lyase (CSE).

72 This study investigated the activities of cystathionine-gamma-lyase (CSE, the enzyme that catalyze

73 ocker, 1 mg/kg) or dl-propargylglycine (PAG, Cystathionine-gamma-lyase [CSE, H(2)S-producing enzyme]

74 Their findings elucidate a role for cystathionine gamma-lyase (CTH), an enzyme in the transs

75 A CRISPR metabolic gene screen revealed cystathionine gamma-lyase (CTH), which converts cystathi

76 wn that H(2)S and its synthesizing enzymes - cystathionine gamma-lyase, cystathionine beta-synthase a

77 Cystathionine gamma-lyase deficiency aggravates obesity-

78 nction; the third, YFR055w, is homologous to cystathionine gamma-lyase encoded by CYS3.

79 beta-elimination product of MSC catalyzed by cystathionine gamma-lyase (gamma-cystathionase).

80 t-degrading enzymes, we engineered the human cystathionine-gamma-lyase (hMGL-4.0) to catalyze the sel

81 l content of cystathionine beta-synthase and cystathionine gamma-lyase, hydrogen sulfide-generating e

82 The H2S-producing capacity of cystathionine gamma-lyase may be regulated in response t

83 ion of putative cystathionine beta-synthase, cystathionine gamma-lyase, or 3-mercaptopyruvate sulfurt

84 These include cystathionine beta-synthase, cystathionine-gamma-lyase, paraxonase 1, 5,10-methylenet

85 genous expression of various KAT enzymes and cystathionine gamma-lyase present in target tissue coupl

86 Deletion of the CYS3 gene encoding cystathionine gamma-lyase resulted in the highest resist

87 A recombinant putative cystathionine gamma-lyase (smCSE) mineralizes CdS from a

88 evented by propargylglycine, an inhibitor of cystathionine gamma-lyase that catalyzes H(2)S formation

89 In contrast to CBS, silencing of cystathionine-gamma-lyase (the expression of which was u

90 e carotid body, express haem oxygenase-2 and cystathionine-gamma-lyase, the enzymes which catalyse th

91 ation of the cystathionine beta-synthase and cystathionine gamma-lyase, two enzymes of the transsulfu

92 d the expression of the H(2)S gene CTH (i.e. cystathionine gamma-lyase) (via quantitative PCR), the p

93 Expression of Bhmt and cystathionine gamma-lyase was decreased when mice were f

94 the carotid body requires the interaction of cystathionine-gamma-lyase with haem oxygenase-2, which g