ライフサイエンスコーパス: cytochrome b

1 16S rDNA, 28S rDNA, Cytochrome oxidase I and Cytochrome b).

2 ia a feedback loop that senses hemylation of cytochrome b.

3 Atovaquone targets parasite cytochrome b.

4 nits and the mitochondrially encoded subunit cytochrome b.

5 eveals the presence of the Y268S mutation in cytochrome b.

6 eakened interaction between this subunit and cytochrome b.

7 ansfer to the Rieske iron-sulfur protein and cytochrome b.

8 ion, which eliminates the proton acceptor in cytochrome b.

9 cripts for cytochrome oxidase II (COXII) and cytochrome b.

10 mitochondrial components, cytochrome c, and cytochrome b.

11 These cysts highly express cytochrome b.

12 llowed by sequencing of a 201-bp fragment of cytochrome b.

13 ochondrial disease-related mutation in human cytochrome b.

14 herichia coli cells harbouring CpcA-labelled cytochrome bd 1 ubiquinol oxidase in the cytoplasmic mem

15 b light chain and encodes p22(phox) protein; cytochrome b-245 or NADPH oxidase 2, and encodes Nox2 or

16 dismutase, and NADPH oxidase-complex adaptor cytochrome b-245, alpha-polypeptide (p22phox) proteins,

17 ecies (ROS) because selective Cybb (encoding cytochrome b-245, beta polypeptide, also known as NOX2)

18 layas based on mitochondrial genomic data of Cytochrome b (380 bps) and D-loop (1000 bps).

19 Cytochrome b 5 (cytb 5) is a membrane protein vital for

20 cytochrome P450 reductase (CPR) and Mn(III) cytochrome b 5 (Mn cyt b 5); the manganese derivative of

21 Cytochrome b (5) partially enhances P450 17A1 lyase acti

22 ological partner proteins myoglobin (Mb) and cytochrome b(5) (b(5)) reveal interprotein ET rates comp

23 The capacity of cytochrome b(5) (b(5)) to influence cytochrome P450 acti

24 nimals and contains three domains similar to cytochrome b(5) (b(5)), CHORD-SGT1 (CS), and cytochrome

25 of Zn-substituted myoglobin (Mb) variants to cytochrome b(5) (b(5)).

26 complex formation between myoglobin (Mb) and cytochrome b(5) (b(5)).

27 pation of cytochrome b(5) reductase (CYB5R), cytochrome b(5) (CYB5), and molybdenum cofactor sulfuras

28 me P450 2B4 were compared in the presence of cytochrome b(5) (cyt b(5)) and NADPH-cyt P450 reductase

29 tuted with Zn-deuteroporphyrin and monitored cytochrome b(5) (cyt b(5)) binding and electron transfer

30 Cytochrome b(5) (cyt b(5)) is one of the key components

31 DPH), cytochrome b(5) reductase (b(5)R), and cytochrome b(5) (cyt b(5)).

32 [POR; HRN (hepatic reductase null) line] or cytochrome b(5) [HBN (hepatic cytochrome b(5) null) line

33 To investigate whether this is because cytochrome b(5) and cytochrome b(5) reductase can act as

34 ome b(5) oxidoreductase (Ncb5or), comprising cytochrome b(5) and cytochrome b(5) reductase domains, i

35 he spontaneous membrane insertion process of cytochrome b(5) and its mutants.

36 bicelles containing uniformly (15)N-labeled cytochrome b(5) are presented and theoretical analyses o

37 Cygb and demonstrate roles for ascorbate and cytochrome b(5) as reductants.

38 chrome b(5) has been deleted in all tissues [cytochrome b(5) complete null (BCN)], which surprisingly

39 ctivities were also significantly reduced by cytochrome b(5) deletion, leading to significantly lower

40 o the previous finding in the liver-specific cytochrome b(5) deletion, suggesting that extrahepatic c

41 However, neither AL10 nor AL21 contain the cytochrome b(5) domain normally present in this class of

42 Ncb5or is the first member of the cytochrome b(5) family shown to have such a heme environ

43 new insight into the factors stabilizing the cytochrome b(5) fold.

44 We have now generated a model in which cytochrome b(5) has been deleted in all tissues [cytochr

45 iver-specific deletion, complete deletion of cytochrome b(5) leads to a neonatal increase in the expr

46 null) line] or cytochrome b(5) [HBN (hepatic cytochrome b(5) null) line].

47 NADH cytochrome b(5) oxidoreductase (Ncb5or) is found in anim

48 The endoplasmic reticulum-associated NADH cytochrome b(5) oxidoreductase (Ncb5or) is widely distri

49 NAD(P)H cytochrome b(5) oxidoreductase (Ncb5or), comprising cyto

50 n Leishmania, we attempted to create NAD(P)H cytochrome b(5) oxidoreductase from L. major (LmNcb5or)

51 b(5) deletion, suggesting that extrahepatic cytochrome b(5) plays a significant role in its disposit

52 We demonstrated recently that cytochrome b(5) plays an important in vivo role in hepat

53 Ascorbate and cytochrome b(5) reduce the oxidized Cygb-NOD intermediat

54 transport chain composed of NADH (or NADPH), cytochrome b(5) reductase (b(5)R), and cytochrome b(5) (

55 cytochrome b(5) (b(5)), CHORD-SGT1 (CS), and cytochrome b(5) reductase (b(5)R).

56 igate whether other reducing enzymes such as cytochrome b(5) reductase (b5R), cytochrome P450 reducta

57 in and methemoglobin (MetHb) concentrations, cytochrome b(5) reductase (CYB5R) enzyme activities, gen

58 ified enzymes suggested the participation of cytochrome b(5) reductase (CYB5R), cytochrome b(5) (CYB5

59 provide strong evidence that cytochrome b(5)/cytochrome b(5) reductase can act as a sole electron don

60 whether this is because cytochrome b(5) and cytochrome b(5) reductase can act as the sole electron d

61 ase (Ncb5or), comprising cytochrome b(5) and cytochrome b(5) reductase domains, is widely distributed

62 PH concentrations below the apparent K(m) of cytochrome b(5) reductase, but well above that for POR,

63 Addition of cytochrome b(5) to CPR-supported l-Trp incubations resul

64 dipocytes, whereas down-regulation of MOSC1, cytochrome b(5) type A (CYB5A), CYB5R1, CYB5R2, or CYB5R

65 ation of MOSC2 and the mitochondrial form of cytochrome b(5) type B (CYB5B) significantly inhibited t

66 Ascorbate and cytochrome b(5) were found to support a high NOD activit

67 for P450 2D6 and P450 3A4 in the presence of cytochrome b(5) with (R)-reticuline as substrate.

68 elate the nonfunctional property of a mutant cytochrome b(5) with its inability to insert into the li

69 CPR-supported d-Trp oxidations (+/-cytochrome b(5)) exhibit Michaelis-Menten kinetics.

70 ther electron acceptors (artificial dyes and cytochrome b(5)).

71 y charge-clustered mutants of rat microsomal cytochrome b(5), E11Q and E44Q, with the same total char

72 shows respective K(m) values for ascorbate, cytochrome b(5), NO, and O(2) of 0.25 mm, 0.3 microm, 40

73 hich to further investigate the functions of cytochrome b(5), particularly in extrahepatic tissues.

74 tive SERR enhancement of the anionic protein cytochrome b(5), whereas functionalization with SiO(2) a

75 esterone receptor membrane component 1) is a cytochrome b(5)-related drug-binding orphan receptor ess

76 esterone receptor membrane component 1) is a cytochrome b(5)-related protein that is up-regulated in

77 p3 transmembrane domain with that of Acta or cytochrome b(5).

78 cs which can be modulated by the addition of cytochrome b(5).

79 These data provide strong evidence that cytochrome b(5)/cytochrome b(5) reductase can act as a s

80 adicals per PS II, and the yield of oxidized cytochrome b 559 by optical difference spectroscopy is 0

81 with PSII intermediate complexes containing cytochrome b (559) Complementation of the Chlamydomonas

82 se that RBD1 participates, together with the cytochrome b (559), in the protection of PSII intermedia

83 s oxidized and ring-opened by enzymes in the cytochrome b(561) and gluconolactonase families, respect

84 ascorbate-regenerating electron transporter cytochrome b(561-1).

85 tion (CHGB, exon 4, Glu348Glu; P=0.002), and cytochrome b-561 (CYB561, intron 1, C719G; P<0.001), an

86 tein, we similarly modified Escherichia coli cytochrome b (562) and the resulting protein behaves in

87 d the heme-binding electron transfer protein cytochrome b(562) (cyt b(562)).

88 eins, namely, the heme binding capability of cytochrome b(562) and the antibiotic degrading beta-lact

89 These observations suggest that the cytochrome b(562) folding energy landscape is minimally

90 was then replaced by a DNA cassette encoding cytochrome b(562) with differing linking sequences at ea

91 sion proteins in a manner similar to that of cytochrome b(562).

92 haped relationship to the reduction state of cytochrome b(566), suggesting that superoxide production

93 s not required for catalytic turnover of the cytochrome b 6 f complex, the role of the single chlorop

94 ingle mutants Tyr112Phe and Trp125Leu in the cytochrome b 6 subunit.

95 reduced accumulation of the ATP synthase and cytochrome b ( 6 )/f complexes.

96 through specific degradation of Rubisco and cytochrome b (6) f and occurs only in the presence of re

97 tion of a NO scavenger decreases the rate of cytochrome b (6) f and Rubisco degradation, whereas NO d

98 The photosynthetic cytochrome b (6) f complex, a homodimer containing eight

99 and decreased electron transport through the cytochrome b (6) f complex.

100 Although the crystal structure of the cytochrome b (6) f from a plant source has not yet been

101 tutively high CEF through the associated PSI-cytochrome b (6) f supercomplex to support robust growth

102 The cytochrome b(6) f (cytb(6) f ) complex has a central rol

103 It is enriched with lipids, cytochrome b(6) f complex, and ATPase while depleted in

104 encoding the cytochrome b(6) subunit of the cytochrome b(6) f complex, was selected to expand our un

105 single core genome locus, petB, encoding the cytochrome b(6) subunit of the cytochrome b(6) f complex

106 mponents of both photosystem I (PSI) and the cytochrome b(6)/f (Cyt b(6)/f) complex.

107 coexist within a large active photosystem I-cytochrome b(6)/f complex.

108 compared the lipid binding properties of the cytochrome b(6)f and bc(1) complexes that function in ph

109 The crystal structure of the cyanobacterial cytochrome b(6)f complex has previously been solved to 3

110 The accumulation of the cytochrome b(6)f complex is also strongly reduced to a l

111 The cyanobacterial cytochrome b(6)f complex is central for the coordination

112 SII but no change in the accumulation of the cytochrome b(6)f complex or photosystem I.

113 A native structure of the cytochrome b(6)f complex with improved resolution was ob

114 ells accumulate 14 to 20% less photosystems, cytochrome b(6)f complex, and ATP synthase but 30% more

115 However, the residual fraction of assembled cytochrome b(6)f complexes exhibits single-turnover elec

116 the presence of two distinguishable pools of cytochrome b(6)f complexes with different functions that

117 ential component of the cytochrome bc(1) and cytochrome b(6)f complexes, and it is exported across th

118 rising multiple subunits and many cofactors, cytochrome b(6)f from the chloroplast of the green alga

119 lic electron transport via photosystem I and cytochrome b(6)f is largely unaffected.

120 Accordingly, measurements of flash-induced cytochrome b(6)f turnover and respiration pointed to a r

121 Cytochrome b, a central catalytic subunit of complex III

122 pressure selects parasites with mutations in cytochrome b, a respiratory protein with low but essenti

123 e p22 phagocytic oxidase subunit (p22(phox)) cytochrome b alpha gene (CYBA) C242T, crystallizable gam

124 We applied mtDNA cytochrome b and 11 microsatellite loci to 26 samples (N

125 n 300 samples were collected and analyzed at cytochrome b and 11 microsatellites loci for investigati

126 eractions between the Rieske protein and the cytochrome b and c sites and provide part of the driving

127 Using paired cytochrome b and control region data across individuals,

128 omplex formation depended on the presence of cytochrome b and Cox3, supporting the idea that supercom

129 itochondria genome, including genes encoding cytochrome b and cytochrome c oxidase I.

130 refore, TtRp likely translocates between the cytochrome b and cytochrome c sites by passive diffusion

131 lity of the Fe/S protein to move between the cytochrome b and cytochrome c(1) subunits of the enzyme.

132 Rieske protein is mobile, moving between the cytochrome b and cytochrome c1 components during turnove

133 sulfur cluster in a conformation proximal to cytochrome b and distal to cytochrome c1.

134 is both required for efficient synthesis of cytochrome b and for protection of the newly synthesized

135 Tyr to Cys mutation cross-links together the cytochrome b and iron-sulfur subunits and renders the ba

136 when the iron-sulfur cluster is proximal to cytochrome b and minimizing binding of the product, redu

137 results suggest that functional variation in cytochrome b and NADH dehydrogenase could mechanisticall

138 ommunication between the two active sites of cytochrome b and open new possibilities for the utilizat

139 systems whereas two negative control genes (cytochrome b and peptidase inhibitor 3) show no signific

140 p6 chaperone complex binds newly synthesized cytochrome b and supports the ordered acquisition of the

141 tterns of molecular evolution differ between cytochrome b and the control region.

142 the downregulation of the redox activity of cytochromes b and c in freezing yeast cells in a contact

143 lled protein structures of the mtDNA marker (cytochrome b) and estimated the environmental envelopes

144 e high-resolution melting profiles from COI, cytochrome b, and 16S ribosomal RNA gene PCR products.

145 inct step preceding transfer of electrons to cytochrome b, and with conformational gating models that

146 complexes (fox, sox, dox and a new putative cytochrome bd) are prevalent in many species (even facul

147 potency and identified the reduction site of cytochrome b as its cellular target.

148 nes cytochrome c oxidase subunit I (COI) and Cytochrome b as well as in the nuclear internal transcri

149 We show that newly synthesized cytochrome b assembled through a series of four assembly

150 ssed mitochondrial precursor transcript (ND5-cytochrome b) but had no effect on steady-state levels o

151 hondria morphologic changes and reduction of cytochrome b/c.

152 which we sequenced two mitochondrial genes, cytochrome b (cob) and cytochrome oxidase (cox1), for mu

153 is, we generated a data set of mitochondrial cytochrome b (cob) and mitochondrial cytochrome c oxidas

154 mitochondrial NADH dehydrogenase5 (nad5) and cytochrome b (cob) transcripts at the nad5-1550 and cob-

155 resulted in sequestration of Cbp3-Cbp6 in a cytochrome b-containing complex, thereby making Cbp3-Cbp

156 Its core subunit, cytochrome b, contains two sites, center P and center N,

157 evolves about 60% as rapidly as that of host cytochrome b, corresponding to approximately 1.2% sequen

158 Two mitochondrial genes, namely, cytochrome b (CYT B) and NADH dehydrogenase subunit 2 (N

159 ypeptide derived from the C-terminal half of cytochrome b (Cyt b) encoded by the mitochondrial genome

160 atin-induced apoptosis due to an increase of cytochrome b (Cyt b) expression and its release from mit

161 l DNA (mtDNA) cytochrome oxidase I (COI) and cytochrome b (Cyt b) gene markers, we inferred the origi

162 ts and newly designed from the mitochondrial cytochrome b (cyt b), cytochrome oxidase I (COI), and 12

163 ur DNA sequences were analysed-mitochondrial cytochrome b (cyt b), nuclear elongation factor-1alpha (

164 tutions in the atovaquone-binding regions of cytochrome b (cytb) and the azithromycin-binding region

165 Mitochondria-encoded Cytochrome B (CYTB) gene mutations were reported in diff

166 one, a ubiquinone analogue, targets C. felis cytochrome b (cytb), of which 30 unique genotypes have b

167 skippers based on three mitochondrial genes (cytochrome b (Cytb), the NADH dehydrogenase subunit 1 (N

168 ely cytochrome c oxidase subunit I (COI) and cytochrome b (cytb), were analysed in silico to identify

169 using mitochondrial genes, and in particular cytochrome b (cytb).

170 Species-specific primers were designed from cytochrome b, cytochrome oxidase I, and 16S rRNA genes t

171 etal transporter 1 (DMT1) 3.2-fold, duodenal cytochrome b (Dcytb) 1.8-fold, and transferrin receptor

172 ensitive than with a mitochondrial probe for cytochrome b despite higher copy numbers of mitochondria

173 Previous work has shown that, although cytochrome bd does not pump protons, turnover is coupled

174 Here, we establish a rate for cytochrome b evolution in avian malaria parasites relati

175 Respiratory chain complex III and possibly cytochrome b function are essential for this increase.

176 ected to an NGS approach targeting two short cytochrome b gene (cytb) fragments on the Illumina MiSeq

177 We characterized the C. felis cytochrome b gene (cytb) in cats with cytauxzoonosis and

178 Our research revealed that a mutation in the cytochrome b gene (G126S) in 35% tested T. urticae popul

179 We found that the parasite cytochrome b gene evolves about 60% as rapidly as that o

180 y applying a previously established parasite cytochrome b gene mutation rate (0.012 mutations per sit

181 A sequences of portions of the mitochondrial cytochrome b gene obtained from gorilla parasites closel

182 throughout Europe using 476-bp mitochondrial cytochrome b gene sequences.

183 ain reaction (PCR) (nested PCR targeting the cytochrome b gene) and quantitative PCR as reference sta

184 sing conserved regions of mitochondrial DNA (cytochrome b gene) was performed to evaluate the halal a

185 ocol that targets the parasite mitochondrial cytochrome b gene.

186 linked to the appearance of mutations in the cytochrome b gene.

187 e diversity in New World Myotis by analyzing cytochrome-b gene variation from an expansive sample ran

188 d targeting mitochondrial ND5, ATPase 6, and cytochrome b genes to amplify 172, 163, 141, 129 and 108

189 oth nuclear (MHC DRB) and mitochondrial DNA (cytochrome b) genes.

190 could distinguish C. felis cytb1 from other cytochrome b genotypes.

191 y using stopped flow, the reduction rates of cytochromes b(H) and c(1) were 403 s(-1) (t(1/2) 1.7 ms)

192 rane potential, and redox states of NADH and cytochromes b(H), b(L), c(1), c, and a,a(3)] were compar

193 introduction, we analyzed L. littorea, using cytochrome b haplotypes.

194 not menaquinone and demethylmenaquinone) and cytochrome bd-I (but not cytochromes bo(3) and bd-II) al

195 The cytochrome bd-I complex of Escherichia coli is a respira

196 Loss of the flavohemoglobin Hmp and cytochrome bd-I elicit the greatest sensitivity to NO-me

197 a mean of approximately 76, indicating that cytochrome bd-I is concentrated in mobile patches in the

198 rmined the structure of the Escherichia coli cytochrome bd-I oxidase by single-particle cryo-electron

199 uent catalytic steps of the Escherichia coli cytochrome bd-I oxidase were investigated by means of ul

200 YtfE), and the expression of the NO-tolerant cytochrome bd-I respiratory oxidase (CydAB).

201 echanisms to evade nitrosative stresses, the cytochrome bd-I respiratory oxidase is the main contribu

202 Intriguingly, the cytochrome bd-I respiratory oxidase was the only system

203 (YTL01) that expresses functional GFP-tagged cytochrome bd-I terminal oxidase complexes under wild-ty

204 ed that in Escherichia coli the component of cytochrome bd-I terminal oxidase, the CydDC complex, shu

205 ehydrogenases and ubiquinone at the level of cytochrome bd-I, which results in oxidative stress.

206 The Salmonella cytochrome bd-II oxidase synergized with nitrate reducta

207 cryptic appBCX genes, predicted to encode a cytochrome bd-II oxidase, conferred a fitness advantage

208 s of our tests suggest that the evolution of cytochrome b in Peromyscus is chiefly governed by purify

209 on-blocking effects are achieved using other cytochrome b inhibitors, which demonstrates that parasit

210 Molecular analyses were applied to mtDNA cytochrome b, intron AM2B1 and 15 microsatellite loci.

211 We show that the reduction site of cytochrome b is also a druggable target.

212 Because cytochrome b is encoded by the maternally inherited para

213 in the mitochondrial inner membrane by which cytochrome b is hemylated.

214 Our results show that cytochrome b is less variable than expected given the di

215 f quinol with oxygen that are observed after cytochrome b is reduced were unaffected by the E272Q sub

216 Cytochrome bd is a quinol oxidase from Escherichia coli,

217 Cytochrome bd is encoded by cydAB from the cydABDC gene

218 omplex has a dual function for biogenesis of cytochrome b: it is both required for efficient synthesi

219 mine the presteady-state kinetics of ISP and cytochrome b(L) reduction by ubiquinol.

220 otential inhibits electron transfer from the cytochrome b(L) to b(H) hemes, thereby promoting the for

221 milar reduction kinetic is also observed for cytochrome b(L), indicating a simultaneous reduction of

222 chrome b synthesis and thus reducing overall cytochrome b levels.

223 es that encode components of NADPH oxidases (cytochrome b light chain and encodes p22(phox) protein;

224 roduce hydrogen peroxide; instead, it uses a cytochrome b-like protein as an electron acceptor.

225 eric [NiFe]-hydrogenase that lacks a typical cytochrome b membrane anchor subunit, which transfers el

226 d with point mutations in the Q(o) pocket of cytochrome b, most notably near the conserved Pro(260)-G

227 dox potential of the FeS cluster, or a E272Q cytochrome b mutation, which eliminates the proton accep

228 II subunit Rieske iron sulfur protein in the cytochrome b-null cells and treatment of wild-type cells

229 Arg-94 in cytochrome b of the Rhodobacter sphaeroides bc(1) comple

230 gene markers, Cytochrome Oxidase I (COI) and Cytochrome b oxidase (COB), have been used to assess DNA

231 with data showing that CydX is required for cytochrome bd oxidase activity, copurification experimen

232 the naphthoquinones, which pass electrons to cytochrome bd oxidase and the anaerobic terminal reducta

233 around E. coli that identified high-affinity cytochrome bd oxidase as an essential bacterial gene pro

234 pothesis that CydX is a subunit of the CydAB cytochrome bd oxidase complex that is required for compl

235 indicate that CydX interacts with the CydAB cytochrome bd oxidase complex.

236 omiscuous Hhy also provided electrons to the cytochrome bd oxidase complex.

237 A M. tuberculosis cytochrome bd oxidase deletion mutant (DeltacydKO) was h

238 noculated with E. coli mutants defective for cytochrome bd oxidase did not.

239 rose, E. coli became strictly dependent upon cytochrome bd oxidase for continued respiration.

240 e propose that the sulfide resistance of the cytochrome bd oxidase is a key trait that permits respir

241 Competitive colonizations revealed that cytochrome bd oxidase is more advantageous than nitrate

242 The cytochrome bd oxidase is not strictly essential for grow

243 , we show that the electron flow through the cytochrome bd oxidase is sufficient to maintain respirat

244 Cytochrome bd oxidase operons from more than 50 species

245 Comparison with another cytochrome bd oxidase reveals structural divergence in t

246 production of reactive oxygen species by the cytochrome bd oxidase was below the detection level of 1

247 that the alternate terminal bd-type oxidase (cytochrome bd oxidase) is capable of maintaining a membr

248 piration and bioenergetics predominantly via cytochrome bd oxidase, and that H(2)S reverses *NO-media

249 In the absence of the back-up cytochrome bd oxidase, growth failed.

250 oxidases, the cytochrome bc(1):aa(3) and the cytochrome bd oxidase, which are jointly required for ox

251 Mutants lacking the high-affinity cytochrome bd oxidase, which is used when oxygen tension

252 tency correlated with an upregulation of the cytochrome bd oxidase-encoding cydABDC operon.

253 Upon genetic deletion of the cytochrome bd oxidase-encoding genes cydAB, Q203 inhibit

254 odes products required for the production of cytochrome bd oxidase.

255 The quinol-linked cytochrome bd oxidases are terminal oxidases in respirat

256 The cytochrome bd oxidases are terminal oxidases that are pr

257 Although cytochrome bd oxidases have been studied for more than 7

258 The results indicate that cytochrome bd oxidases like the heme-copper oxidases bre

259 However, in cytochrome bd oxidases, the fourth electron is donated b

260 The cytochrome b oxidation center is a validated antimalaria

261 Finally, homology models of the cytochrome b protein revealed a substitution in rutilus

262 on with its substrate, the newly synthesized cytochrome b protein.

263 dases (RTOs), cytochrome c oxidase (Cox) and cytochrome bd quinol oxidase (Cyd), are present in the p

264 in a non-linear inhibition of the extent of cytochrome b reduction by quinol together with a shift o

265 sult in a linear inhibition of the extent of cytochrome b reduction through center N.

266 robe based on sequences of the mitochondrial cytochrome b region was designed.

267 different single amino acid substitutions in cytochrome b rendering the yeast resistant to the inhibi

268 l methods, i.e. Hake-ITS1-RFLP (89%) or Hake-Cytochrome b-RFLP (83%).

269 In vitro response and cytochrome b sequence did not indicate atovaquone resist

270 In vitro response to atovaquone and cytochrome b sequence of clinical isolates were determin

271 ern South China Seas using the mitochondrial cytochrome b sequences and Bayesian Skyline Plot analyse

272 These new data (188 cytochrome b sequences) bring the total number of sequen

273 METHODOLOGY AND PRINCIPAL FINDINGS: Cytochrome-b sequences were generated and phylogenetical

274 Failure to hemylate cytochrome b sequesters the Cbp3-Cbp6 complex in early a

275 erial system, we show that mutation G167P in cytochrome b shifts the equilibrium distribution of ISP-

276 The nucleotide sequence of cytochrome b showed extremely high utility for recent ep

277 he quinone when the Rieske protein is in the cytochrome b site, as the residue experiencing the remar

278 d between the hydroquinone and His154 at the cytochrome b site.

279 we show that a conserved Tyr residue of the cytochrome b subunit of cytochrome bc(1) is critical for

280 ia eutropha, including the membrane-integral cytochrome b subunit, was investigated electrochemically

281 ex, thereby making Cbp3-Cbp6 unavailable for cytochrome b synthesis and thus reducing overall cytochr

282 ntermediates, thereby causing a reduction in cytochrome b synthesis via a feedback loop that senses h

283 e, we report that Cbp3-Cbp6 also coordinates cytochrome b synthesis with bc(1) complex assembly.

284 acquisition that triggers the progression of cytochrome b through successive assembly intermediates.

285 ochrome b were observed in 2 cases (ratio of cytochrome b to ND1: 0.80 [95% CI, 0.68-0.92] vs 0.99 [9

286 . monocytogenes has two terminal oxidases, a cytochrome bd-type (CydAB) and a cytochrome aa 3-type me

287 ases, an aa3-type cytochrome c oxidase and a cytochrome bd-type menaquinol oxidase.

288 In Escherichia coli, the biogenesis of both cytochrome bd-type quinol oxidases and periplasmic cytoc

289 Cytochrome bd-type quinol oxidases catalyze the reductio

290 e test for evidence of positive selection on cytochrome b variation within and among species of the e

291 Using cytochrome b variation, we characterized phylogenetic di

292 nteraction sites of yeast Cbp3 with Cbp6 and cytochrome b via site-specific photo-cross-linking.

293 extraction of DNA, followed by nested PCR of cytochrome b, was the optimal strategy, allowing reliabl

294 munoreactivities of cytochrome oxidase 1 and cytochrome b were found in HD patients relative to contr

295 Deletions at the segment of cytochrome b were observed in 2 cases (ratio of cytochro

296 t cells deficient in the complex III subunit cytochrome b, which are respiratory incompetent, increas

297 Surprisingly, CcmF is a cytochrome b with a haem never before realized, and in v

298 volves interactions of the newly synthesized cytochrome b with assembly factors and structural comple

299 ) complex and its effect on the reduction of cytochrome b with center P blocked.

300 ts the catalytic quinol oxidation Qo site in cytochrome b with cytochrome c1.