ライフサイエンスコーパス: cytochrome c'

1 in the presence of NADPH by cell-free assay (cytochrome c).

2 f hemes through deprotonated histidine (e.g. Cytochrome c).

3 itin, eglin c, ribonuclease A, lysozyme, and cytochrome c).

4 a number of heme protein systems, including cytochromes c'.

5 state abundances of both c-type cytochromes, cytochrome c (1) and cytochrome c The observed reduction

6 ndance of complex III could be attributed to cytochrome c (1) being one of its subunits.

7 We study a protein (horse cytochrome c, 104 amino acids) whose fluorescence increa

8 c, as compared with those with nondetectable cytochrome c (11% versus 1%; P<0.001).

9 with decreasing protein molecular mass: for cytochrome c (12.3 kDa) and lysozyme (14.3 kDa) a detect

10 (PNA) can be used to control the assembly of cytochrome c (12.5 kDa, pI 10.5) and azurin (13.9 kDa, p

11 exhibited significant rates of reduction of cytochrome c (160 min(-1), largely superoxide dismutase-

12 efficiently as wild type MSR but the rate of cytochrome c, 2,6-dichloroindophenol, and menadione redu

13 l mortality than patients with nondetectable cytochrome c (6% versus 1%; P<0.001).

14 SI centers that are prebound by plastocyanin/cytochrome c (6) in darkness (about 60% in both cyanobac

15 isotopes at the fundamental distribution of cytochrome c(+8) (m/z approximately 1549) were nearly ba

16 by DESI-MS, were 100% for melittin, 100% for cytochrome c, 90% for myoglobin, and 65% for bovine seru

17 properties are reminiscent of the A-state of cytochrome c, a compact denatured form found under acidi

18 fic ablation of the proapoptotic function of cytochrome c, a key regulator of mitochondria-mediated a

19 ress-triggered changes in the translation of cytochrome c, a pivotal regulator of apoptosis.

20 hondrial function and reduces the release of cytochrome c, a pro-apoptotic cell death factor.

21 the presence of reactive oxygen species and cytochrome c, a proapoptotic peroxidase that is released

22 lso propose an orientation of membrane-bound cytochrome c, a protein for which the membrane orientati

23 SRCD measurements of the folding kinetics of cytochrome c, a small, fast-folding protein.

24 om proteins; a deamidated tryptic peptide of cytochrome c, a tryptic peptide from unfolded and deamid

25 mitochondrial membrane potential, release of cytochrome c, activation of Bax and Bak, and processing

26 Ad-MMP-9 infection induced the release of cytochrome c, activation of caspase-9 and -3, and cleava

27 mitochondrial permeability shift, release of cytochrome c, activation of caspases, and subsequent fra

28 3 and 9) and in the mitochondrial (cytosolic cytochrome C, AIF, Mcl-1, Bcl-2, Bcl-xl, Bax, Bad, and p

29 res contained four basic proteins (lysozyme, cytochrome c, alpha-chymotrypsinogen A, and ribonuclease

30 Release of cytochrome c, an activator of caspase-9, from mitochondr

31 Cytochrome c, an essential electron carrier in mitochond

32 (flavoprotein, succinate dehydrogenase, and cytochrome c) and the synthesis and activity of key deni

33 depolarizes mitochondria membranes, releases cytochrome c, and activates caspases-9 and -3 and death

34 hondrial membrane depolarization, release of cytochrome c, and activation of both intrinsic and extri

35 mitochondrial membrane potential, release of cytochrome c, and activation of caspase-3.

36 of mitochondrial transition pore, release of cytochrome c, and activation of caspase-9 and -3.

37 chondrial proteins, release of the apoptogen cytochrome c, and activation of executioner caspase-3 we

38 islets was strongly correlated with reduced cytochrome c, and agents that acutely and specifically r

39 ized HAzPC associated with mitochondria, and cytochrome c, and apoptosis-inducing factor escaped from

40 Using myoglobin, cytochrome c, and beta-2-microglobulin as model protein

41 formed in ESI for three proteins (ubiquitin, cytochrome c, and carbonic anhydrase II) were investigat

42 horylation of Bcl-2, expression of cytosolic cytochrome c, and caspase 3 activity.

43 ell death with immunostaining for annexin V, cytochrome C, and caspases 3 and 9 pointing to induction

44 Bax expression, a disturbed distribution of cytochrome c, and cleaved caspase-3 positive staining in

45 e purification of the engineered peroxidase, cytochrome c, and covalent complex, along with activity

46 how a reduction of mitochondrial components, cytochrome c, and cytochrome b.

47 aspase-8, deficient release of mitochondrial cytochrome c, and delayed activation of both caspase-9 a

48 duced unfolding of SNase, from acid-unfolded cytochrome c, and from folding of Azoarcus ribozyme.

49 in blocking apoptosis by reduction of ferric cytochrome c, and gentle tuning of NO concentration in t

50 CRALBP, cytochrome C, and GNB3 showed that the RPE interdigitati

51 l associated molecules, including clusterin, cytochrome C, and HTRA2/OMI.

52 enzymatic activity and immunoreactivity for cytochrome c, and identical functional properties shared

53 ious Mossbauer investigations on a bacterial cytochrome c, and is not reproduced by the simulations.

54 of the mass spectral response for myoglobin, cytochrome c, and lysozyme is presented for laser electr

55 apped, translated into a solution containing cytochrome c, and monitored for 3-NBS leakage.

56 me using "protein charge ladders" of azurin, cytochrome c, and myoglobin.

57 as well as mitochondrial release of AIF and cytochrome c, and subsequent activation of caspase-9 in

58 on of the effector caspase-9, independent of cytochrome c, and subsequently the processing of the exe

59 f caspases, apoptogenic mitochondrial factor cytochrome c, and the Bcl-2 family proteins in DR6-induc

60 R) in portal blood, the release of cytosolic cytochrome c, and the cleaved caspase 9 expression in in

61 cular, appeared to be restricted to nitrated cytochrome c, and thus, no association of non-nitrated c

62 elease, lipid peroxidation, translocation of cytochrome c, and TUNEL labeling in the ischemic cortex.

63 Proteins carbonic anhydrase, cytochrome c, and ubiquitin were used to demonstrate the

64 esults constitute the molecular mechanism of cytochrome c- and dATP-mediated activation of Apaf-1.

65 2 positions (C(18:2)/C(18:2)), formed in the cytochrome c- and H(2)O(2)-driven enzymatic oxidation re

66 acid-binding protein, myoglobin and somatic cytochrome-C) and others (creatine kinase M, malate dehy

67 e myocardial levels of lipid hydroperoxides, cytochrome-c, and mitochondrial aconitase activity were

68 ns c-Jun N-terminal kinase 3, caspase 3, and cytochrome C, Annexin V staining, RNA degradation, and o

69 tryptophans in three well-studied proteins, cytochrome c, apomyoglobin, and lysozyme, as a function

70 her a caspase-dependent mechanism, involving cytochrome c, apoptosis protease-activating factor-1 (Ap

71 avage; and Bcl-2 phosphorylation, as well as cytochrome c, apoptosis-inducing factor (AIF), and endon

72 The release of the apoptogenic factors cytochrome c, apoptosis-inducing factor (AIF), and proin

73 apparent K(d),of ~15.8 muM and competes with cytochrome c (apparent K(d) of ~1.31 muM) for binding to

74 D ( approximately 16% decrease, males only), cytochrome C ( approximately 19% decrease, females only)

75 ase of intermembrane space proteins, such as cytochrome c, are early events during intrinsic (mitocho

76 of free reactive oxygen species, rather than cytochrome c, are rate limiting.

77 Apoptotic factors, including cytochrome c, are released through these pores from the

78 Cytochromes c' are pentacoordinate heme proteins with st

79 a picosecond timescale for the heme protein, cytochrome c, as a function of oxidation and hydration,

80 gment-elevation AMI patients with detectable cytochrome c, as compared with those with nondetectable

81 s approach to the absolute quantification of cytochrome C (as target compound) in a commercial protei

82 terial heme protein Alcaligenes xylosoxidans cytochrome c' (AXCP) forms a novel five-coordinate heme-

83 between Fe2S2- (adrenodoxin-like) and heme- (cytochrome c) binding domains.

84 % (w/v) bovine serum albumin and 0.01% (w/v) cytochrome C (both are proteins), and 0.002% (w/v) human

85 ation and identification of proteins such as cytochrome c, bovine serum albumin, and high-molecular w

86 brane pores large enough to release not only cytochrome c, but also allophycocyanine, a protein of 10

87 erobic electron acceptors include oxygen and cytochrome c, but an acceptor that can function under an

88 electrons coming from NADH and ubiquinol to cytochrome c, but it is also capable of producing signif

89 sequent release of the mitochondrial protein cytochrome c, but the second mitochondrion-derived activ

90 Here, we identify a dihaem cytochrome c (C8j_0815; TsdA) as the enzyme responsible.

91 a result, during steady-state turnover with cytochrome c, calmodulin now deactivates the enzyme and

92 induced mitochondrial trafficking of Bax and cytochrome c, caspase-3 activation, and oxidative stress

93 he product of the enzymatic reaction reduces cytochrome c, causing an increase in absorbance at 550 n

94 (CcP)], suggesting both ascorbate (Asc) and cytochrome c (Cc) peroxidase activity.

95 Cytochrome c (CC)-initiated Apaf-1 apoptosome formation

96 loys a Trp191(*+) radical to oxidize reduced cytochrome c (Cc).

97 s to the periplasmic enzymes that reduce apo-cytochrome c (CcsX) or repair oxidative protein damages

98 H2O2-dependent apoptosis in mouse embryonic cytochrome c(+/+) cells than in cytochrome c(-/-) cells.

99 se embryonic cytochrome c(+/+) cells than in cytochrome c(-/-) cells.

100 ria differed primarily at a Raman biomarker, cytochrome c, corresponding to a bacteroid-specific term

101 ns (i.e., myoglobin, carbonic anhydrase, and cytochrome c) could be analyzed by SEC-ESI-MS using diff

102 arkers of WAT mitochondrial protein content (cytochrome c, COXIV-subunit I, and citrate synthase acti

103 Biomolecule cytochrome c (Cty c), a small molecule of a chain of ami

104 that miR-34a regulates the BBB by targeting cytochrome c (CYC) in vitro.

105 and the nuclear-encoded subunits of COX and cytochrome c (CYC), we hypothesized that some codons in

106 lus fumigatus alternative oxidase (aoxA) and cytochrome C (cycA) null mutants and assessed their abil

107 rving as respiratory electron shuttle, ferri-cytochrome c (cyt c) acts as a peroxidase; i.e., it cata

108 ns and ER stress as shown by increased HSP60/Cytochrome C (Cyt C) and CHOP-ATF3 levels respectively.

109 d, catalytic circuit based on photosystem I, cytochrome c (cyt c) and human sulfite oxidase (hSOX).

110 An axial S(Met) bond is also present in cytochrome c (cyt c) and is generally thought to increas

111 proach with three variants of a heme protein cytochrome c (cyt c) and show that the method yields a w

112 tive stress sensor contains the heme protein cytochrome c (cyt c) as sensing element whose spectral r

113 Cytochrome c (cyt c) binds to and penetrates lipid struc

114 tivation of peroxidase catalytic function of cytochrome c (cyt c) by anionic lipids is associated wit

115 y to investigate the early folding states of Cytochrome c (cyt c) by monitoring the distance between

116 ted for the first time that the heme protein cytochrome c (Cyt c) can enter the interior of a MOF des

117 The active site of cytochrome c (Cyt c) consists of a heme covalently linke

118 cribe advancements in sensing technology for cytochrome c (cyt c) detection, at point-of-care (POC) a

119 alent mechanisms, are employed to immobilize cytochrome c (cyt c) for electrochemical analysis.

120 The release of cytochrome c (cyt c) from mitochondria is an important e

121 denatured states and the native structure of cytochrome c (Cyt c) from Saccharomyces cerevisiae.

122 activation is accompanied by the release of cytochrome c (cyt c) from the intermembrane gap and subs

123 Native cytochrome c (cyt c) has a compact tertiary structure wi

124 Horse heart cytochrome c (cyt c) has emerged as a paradigm for the s

125 Cytochrome c (Cyt c) has evolved to become an important

126 Mammalian cytochrome c (Cyt c) has two primary functions: transfer

127 CRALBP and cytochrome C (Cyt C) immunolabeling revealed that hyperr

128 competent peroxidase form of pentacoordinate cytochrome c (cyt c) in a complex with a mitochondria-sp

129 vine serum albumin (BSA), lysozyme (lyz) and cytochrome c (cyt c) in singular and competitive manner

130 of Thr78Cys/Lys79Gly/Met80X mutants of yeast cytochrome c (cyt c) in which Cys78 becomes one of the a

131 It is well known that cytochrome c (Cyt c) is a crucial death regulator that t

132 Cytochrome c (cyt c) is a heme-containing protein that p

133 Cytochrome c (cyt c) is a small hemoprotein involved in

134 Cytochrome c (cyt c) is a small soluble heme protein cha

135 Cytochrome c (Cyt c) is an apoptosis-initiating protein

136 Cytochrome c (Cyt c) is an important biomarker in cell l

137 Cytochrome c (Cyt c) is commonly used as intrinsic bioma

138 Although the primary function of cytochrome c (cyt c) is electron transfer, the protein c

139 Cytochrome c (cyt c) is known for its role in the electr

140 Cytochrome c (cyt c) is one of the most widely studied b

141 arly mitochondria-specific cardiolipin (CL), cytochrome c (cyt c) loses its tertiary structure and it

142 cytochrome c synthase (HCCS) is required for cytochrome c (cyt c) maturation and therefore respiratio

143 n one-shot adsorption of chemically-modified cytochrome c (cyt c) onto bare gold electrodes.

144 ies designed to investigate the integrity of cytochrome c (cyt c) photo-cross-linked via MPE.

145 tion of cardiolipin (CL) by its complex with cytochrome c (cyt c) plays a crucial role in triggering

146 Cytochrome c (Cyt c) plays a vital role in the mitochond

147 The multifunctional protein cytochrome c (cyt c) plays key roles in electron transpo

148 has been suggested that the alkaline form of cytochrome c (cyt c) regulates function of this protein

149 tic stress induces apoptosis, which involves cytochrome c (Cyt c) release from mitochondria and subse

150 Cytochrome c (cyt c) release from mitochondria is accept

151 Cytochrome c (cyt c) release upon oxidation of cardiolip

152 s of the spontaneous reversible unfolding of Cytochrome c (Cyt c) under native conditions have led to

153 dy the reversible unfolding and refolding of cytochrome c (Cyt c) under native conditions.

154 Herein, the structural change of cytochrome c (Cyt c) upon encapsulation within a hierarc

155 Using a collection of dye-labeled cytochrome c (cyt c) variants, we identify transformatio

156 Cytoplasmic cytochrome c (cyt c) was released early in both cases, b

157 Interactions of cytochrome c (cyt c) with cardiolipin (CL) are important

158 Interactions of cytochrome c (cyt c) with cardiolipin (CL) partially unf

159 interaction of the simple, globular protein cytochrome C (Cyt C) with MPMN surfaces using experiment

160 rochemical immunosensor for the detection of cytochrome c (cyt c), a heme containing metalloprotein u

161 Cytochrome c (cyt c), a mitochondrial intermembrane elec

162 Globular proteins, such as cytochrome c (cyt c), display an organized native confor

163 Cytochrome c (cyt c), required for electron transport in

164 assembly and prevent apoptosis triggered by cytochrome c (Cyt c).

165 nsfer reorganization free energy (lambda) of cytochrome c (Cyt) in electrostatic complexes that mimic

166 the adsorption behavior of the redox protein cytochrome c (Cyt-C) onto different interfaces, namely,

167 Various standard proteins (e.g. cytochrome C (Cyt-C), myoglobin (MYO) and bovine serum a

168 re is also a required role for mitochondrial cytochrome c (cyt-c).

169 hieved using redox cofactors namely oxidized cytochrome-c (Cyt-c) and Co-enzyme-Q (Co-Q) immobilized

170 The mesh is functionalized with cytochrome-c (cyt-c) and incorporated as a working elect

171 We have demonstrated that a protein (cytochrome c (Cytc c) or bovine serum albumin (BSA)) can

172 of mitochondrial permeability and release of cytochrome c (CytC) and apoptosis-inducing factor (AIF)

173 as an oligopeptide stopper, we have employed cytochrome C (CytC) as a protein stopper to produce the

174 oxygen to water, the one-electron reductant Cytochrome c (Cytc) being the source of electrons.

175 Monolayers of the redox protein Cytochrome C (CytC) can be electrostatically formed on a

176 Cytochrome c (Cytc) is a multifunctional protein that op

177 Cytochrome c (Cytc) is a multifunctional protein, acting

178 The combined use of cytochrome c (CYTc) loss-of-function mutants and respira

179 r the directed immobilization of horse heart cytochrome c (cytc) on gold electrode surfaces to achiev

180 tion (MOMP) via BAK and BAX oligomerization, cytochrome c (cytc) release, and caspase activation are

181 Mammalian cytochrome c (Cytc) transfers electrons from the bc(1) c

182 -phycoerythrin (R-PE) and positively charged cytochrome c (CYTC) within the same DFGF apparatus is sh

183 te ETp across the electron-mediating protein cytochrome c (CytC), measured in a monolayer configurati

184 with alpha-chymotrypsin (ChT), histone, and cytochrome c (CytC).

185 rom mitochondria inhibited BAK/BAX-dependent cytochrome c (cyto c) release.

186 rate synthase), and the expression levels of cytochrome c, cytochrome c oxidase subunit 1, and mitoch

187 + H2O) with electrons donated by periplasmic cytochrome c (cytochrome c-dependent NO reductase; cNOR)

188 hibitor, prevented the increase in cytosolic cytochrome c, decreased caspase-3 activation, and partia

189 polarization of mitochondria, and release of cytochrome c, demonstrating its important role as an ant

190 The diheme cytochrome c (DHC) from Rhodobacter sphaeroides is a sol

191 es for all three monomeric proteins, and for cytochrome c, dimers of significant intensity are also o

192 in an observed sequence coverage of 79% for cytochrome C (eight peptides), 47% for beta-lactoglobuli

193 hampers mitochondrial respiration, releases cytochrome c, elevates mitochondrial lipid peroxidation,

194 ectron transfer-triggered folding of reduced cytochrome c, far-UV time-resolved circular dichroism (T

195 65 mM SDS to induce the MG state in oxidized cytochrome c, folding of redcyt c was triggered with fas

196 f a relatively low molecular weight protein, cytochrome-c, for ESI-MS detection.

197 -coordinate heme-nitrosyl complex (5c-NO) of cytochrome c' from Alcaligenes xylosoxidans (AXCP) in wh

198 either heme face exists, as in the microbial cytochrome c' from Alcaligenes xylosoxidans (AxCYTcp), w

199 The five-coordinate NO-bound heme in cytochrome c' from an overexpressing variant of denitrif

200 tured state of a class II c-type cytochrome, cytochrome c' from Rhodopseudomonas palustris.

201 Examples include cytochrome c, green fluorescent protein, Mito-Tracker Re

202 re reveals a core that is typical of class I cytochromes c, having alpha-helices folded into a compac

203 using solutions of 1pmol/mul angiotensin II, cytochrome c, hemoglobin, and beta-casein.

204 -Volmer quenching constants (Ksv) for hemin, cytochrome c, hemoglobin, and myoglobin were 5.6x10(7),

205 ta defensin 1, truncated human lymphotactin, Cytochrome C, holo hemoglobin-alpha, ovalbumin, human tr

206 ged: the first was to maintain the KD of the cytochrome c' in the 1 microM range, and the second was

207 The association with nitrated cytochrome c, in particular, appeared to be restricted t

208 n conformations of a small globular protein, cytochrome c, in the presence of guanidine hydrochloride

209 d had greater amounts of cytosolic mtDNA and cytochrome c, increased apoptosis, and more IL-1beta sec

210 eased activation of caspase-3 and release of cytochrome c, indicating that a mitochondrial pathway wa

211 Cytochrome c' is a heme protein from a denitrifying vari

212 wnstream of the mitochondria, with cytosolic cytochrome c, kills brain tumor cells but not normal bra

213 nents abolishes the ability of cells to form cytochrome c, leading in the case of Rhodobacter capsula

214 agonist could be shown to induce release of cytochrome c, leading to activation of caspase 9.

215 mP in a complex with its substrate, L. major cytochrome c (LmCytc) to 1.84 A, and compared the struct

216 PDGF, but not cytochrome C, localized at a protrusion tip induced a co

217 ss of bovine thrombin, bovine serum albumin, cytochrome C, lysozyme and myoglobin.

218 ion to peptides, gas-phase HDX of ubiquitin, cytochrome c, lysozyme, and apomyoglobin were examined.

219 The glycated species of cytochrome C, lysozyme, and beta-casein formed during gl

220 s circumvented by deleting the gene encoding cytochrome c (M) (CytM), a cryptic c-type heme protein w

221 Cytochrome c [M + 5H](5+) ions present in one conformer

222 (NANOG, MYOD), antibodies, native proteins (cytochrome C), magnetic nanoparticles (MNPs), and nuclei

223 We show that as neurons mature, cytochrome c- mediated apoptosis progresses from inhibit

224 horylation and fatty acid oxidation, such as cytochrome c, medium-chain acyl-CoA dehydrogenase, and a

225 Mitochondrial biogenic (cytochrome c, mitochondrial transcription factor A), mor

226 dione or benzoquinone and weak activity with cytochrome c, molecular oxygen, and 5,5'-dithio-bis-2-ni

227 releases of a small protein (8 muL of 5 muM cytochrome-c, molecular mass ~12 kDa) and exhibits ~1 mi

228 The spectra for smaller proteins (ubiquitin, cytochrome c, myoglobin) again resemble those at AP, pro

229 Tested on cytochrome c, myoglobin, and beta-lactoglobulin cross-li

230 digestion of four model proteins: melittin, cytochrome c, myoglobin, and bovine serum albumin.

231 Good-quality ESI-MS spectra of cytochrome c, myoglobin, and lysozyme as test proteins i

232 A mixture containing four model proteins (cytochrome c, myoglobin, bovine serum albumin (BSA), and

233 The diffusion rates of lysozyme, cytochrome c, myoglobin, ovalbumin, bovine serum albumin

234 usion rates of 6 Hz are used for analysis of cytochrome c, on a DTIMS Q-TOF similar rates were obtain

235 the transport of electrons from ubiquinol to cytochrome c (or alternate physiological acceptors), yet

236 V(max) of each in four assays: reduction of cytochrome c, oxidation of NADPH, 17alpha-hydroxylase ac

237 Compared with reduced cytochrome c, oxidized cytochrome c binds to tRNA with a

238 opulations specific for the model Ags pigeon cytochrome c (PCC) and hen egg lysozyme (HEL).

239 tra of the B-bands of bovine and horse heart cytochrome c (pH 7.0) exhibit a pronounced couplet that

240 , Apaf-1, procaspase-9, procaspase-3, Hsp70, cytochrome c, PHAPI, CAS, and regulatory compounds to mi

241 -to-Bcl-2 ratio (R(2) = 0.83) and release of cytochrome c (R(2) = 0.92), but preceded in time the cas

242 The folding of reduced cytochrome c (redcyt c) is increasingly being recognized

243 s hemoglobin, myoglobin, cytochrome P450 and cytochrome c, respectively.

244 quantifiable across triplicates for HSA and cytochrome C, respectively.

245 d to be 350 and 25 mg/ml for rusticyanin and cytochrome c, respectively; cytochrome a was present as

246 energized complex II and transferred them to cytochrome c, restoring ATP biosynthesis rates.

247 atalytic amounts of cytochrome c oxidase and cytochrome c, results in ISP reduction.

248 the refolding of Rhodopseudomonas palustris cytochrome c' reveals dramatic differences between two v

249 -cytochrome c and Rhodopseudomonas palustris cytochrome c', shows that foldable sequences deviate sig

250 anied by mitochondrial injury and release of cytochrome c, Smac, and AIF into the cytosol and caspase

251 Bax:Bcl-2 ratio and mitochondrial release of cytochrome c, Smac, and AIF.

252 ease efficiency for the apoptogenic proteins cytochrome c, Smac, and HtrA2 in response to Bim.

253 pathological changes and increased levels of cytochrome c, Smac/DIABLO and AIF in the cytosol while t

254 ay, leading to increased cytosolic levels of cytochrome c, Smac/Diablo and Omi/HtrA2, and activation

255 embrane potential, attenuated the release of cytochrome c, Smac/DIABLO, and apoptosis inducing factor

256 mitochondrial depolarization and release of cytochrome c, Smac/DIABLO, and apoptosis-inducing factor

257 The protein expressions of mitochondrial cytochrome c, stromal cell-derived factor-1, C-X-C chemo

258 n transferase activity with equine and yeast cytochrome c, suggesting a conservation of the enzymatic

259 Apaf-1 and rendered the cells insensitive to cytochrome c, suggesting a potential role for Rsk signal

260 th released the apoptogenic factors Smac and cytochrome c, suggesting that they are primed for cell d

261 o affect the buried hydrogen bond network of cytochrome c, suggesting that this network is an importa

262 While the N-terminal domain is a class I cytochrome c, the C-terminal domain shows no similarity

263 ee proteins of increasing intrinsic disorder-cytochrome c, the tumor suppressor protein p53 DNA bindi

264 The surprising finding is that, unlike for cytochrome c, there is an observable folding intermediat

265 nted, display remodelled cristae and release cytochrome c, thereby driving apoptosis.

266 imilar to the previously reported results on cytochrome c, these fragment ions form near residues kno

267 that reduced DSD-Fdm transfers electrons to cytochrome c, thus generating the reduced cyt c stoichio

268 r binding affinity of rebaudioside A towards cytochrome c, thus supporting their host-guest relations

269 ] of the four model proteins ranged from 20 (cytochrome c) to 800 amol (BSA).

270 id hydrolysis to degrade a standard protein, cytochrome c, to produce many di/tripeptides with known

271 ase uses electrons donated by its substrate, cytochrome c, to reduce oxygen to H2O.

272 t with MPH (10mg/kg) decreased caspase-3 and cytochrome c; treatment with MPH (2 and 10mg/kg) increas

273 abilities are demonstrated for ubiquitin and cytochrome c, two common model proteins for structure an

274 obilities of single multiply charged ions of cytochrome c, ubiquitin, myoglobin, and bovine serum alb

275 A major relaxation of heme ruffling in cytochrome c, upon binding to the mitochondrial membrane

276 ein SERS spectra of a layer of test protein, Cytochrome-c, using a custom-made Otto-Raman spectroscop

277 reactivity of the reduced FMN domain toward cytochrome c; (v) response to calmodulin binding; and (v

278 of model proteins in aqueous media, such as cytochrome c, was also examined, yielding spectra with a

279 In experiments using cytochrome c, we distinguish dynamic behavior in loops,

280 functionally relevant structural changes in cytochrome c, we measured the absorption and electronic

281 ins (transferrin, myoglobin, hemoglobin, and cytochrome c) were separated by high-performance liquid

282 the SH3 domain, dihydrofolate reductase, and cytochrome c, where the transparent window vibrational p

283 calmodulin (CaM)-free and CaM-bound nNOS to cytochrome c, whereas hinge lengthening relieved repress

284 ngly abolish formation of both holo-CcmE and cytochrome c, whereas previously reported point mutation

285 ants, such as bovine cytochrome c and equine cytochrome c, which differ by only three amino acids.

286 MOM permeabilization, causing the release of cytochrome c, which effectively commits the cell to die.

287 ith anionic lipids (such as cardiolipin) and cytochrome c, which exerts a peroxidase activity.

288 eabilization (MOMP), allowing the release of cytochrome c, which interacts with Apaf-1 to trigger cas

289 tion and inhibits the peroxidase activity of cytochrome c, which is involved in its release from mito

290 2)S also reduces CcO's biological reductant, cytochrome c, which normally derives its reducing equiva

291 anges to key apoptotic regulators, including cytochrome c, which primes cells for death.

292 he dissociated heme to the protein moiety in cytochrome c, which we assign to the presence of covalen

293 hondrial damage and translocation of Bax and cytochrome c, which were then followed by caspase-3 acti

294 n aberrant activation of a testis isoform of cytochrome c, which, albeit expressed at low levels, was

295 different proteins (Trp-cage, myoglobin, and cytochrome c) with folding time constants that differ by

296 1 functioned as a translational repressor of cytochrome c, with interventions to silence TIA-1 dramat

297 roxidase (ZnCcP) in complex with yeast iso-1-cytochrome c (yCc) diffract to higher resolution (1.7 A)

298 ection values of the charge states of equine cytochrome c (z = 9-16), and values are in good agreemen

299 e demonstrate that Zn(II) porphyrin in Zn(II)cytochrome c (Zn cyt c) is a fluorescence resonance ener

300 phyrin (ZnP) chromophore in zinc-substituted cytochrome c (Zn-cyt c) and an Alexa Fluor dye attached