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1 and also co-operates for CAR assembly during cytokinesis.
2 e, and that Ace2 asymmetry is restored after cytokinesis.
3 hat is of interest to researchers working on cytokinesis.
4 cooperate to position the division site for cytokinesis.
5 F ECT-2, a RhoA activator also essential for cytokinesis.
6 A specifically drives bleb retraction during cytokinesis.
7 asis and is potentially a novel regulator of cytokinesis.
8 to localize to and track MT plus-ends during cytokinesis.
9 omplex and regulates mitotic progression and cytokinesis.
10 and interactions of centralspindlin in late cytokinesis.
11 f a contractile actomyosin ring (CAR) during cytokinesis.
12 ssion yeast cells through spatial control of cytokinesis.
13 onent in the signaling pathways coordinating cytokinesis.
14 lular functions, such as DNA replication and cytokinesis.
15 Ins(4,5)P(2) homeostasis required for normal cytokinesis.
16 orchestrate key events in cell division and cytokinesis.
17 ranging from cell polarity and migration to cytokinesis.
18 paired chromosome segregation and incomplete cytokinesis.
19 of either nucleator affects the kinetics of cytokinesis.
20 electively bind to these overlaps to control cytokinesis.
21 ough loss of PP2A in yeast causes defects in cytokinesis.
22 k pathway, a signaling cascade essential for cytokinesis.
23 lying distinct functions in karyokinesis and cytokinesis.
24 ir known roles in nonmuscle myosin-dependent cytokinesis.
25 aphase transition and growth resumes in late cytokinesis.
26 e cardiomyocytes that complete cell division/cytokinesis.
27 nals coordinating cell cycle progression and cytokinesis.
28 ers in zygotes fixed before and during 1(st) cytokinesis.
29 ytoplasm dynamics far from the cortex during cytokinesis.
30 of mechanistically incompatible processes of cytokinesis.
31 both types of large-scale endocytosis and in cytokinesis.
32 2, enhanced localized RhoA activation during cytokinesis.
33 mislocalize, which blocks ER inheritance and cytokinesis.
34 is and maintenance, as well as for bacterial cytokinesis.
35 pindle structure, chromosome segregation and cytokinesis.
36 Septin-2, a cytoskeletal factor involved in cytokinesis.
37 positions pPLK4 to play a functional role in cytokinesis.
38 in plant defense, growth, light response and cytokinesis.
39 n, chromosome condensation and movement, and cytokinesis.
40 oceed and result in successful completion of cytokinesis.
41 exocytosis, endocytosis, protein sorting and cytokinesis.
42 nsuring proper central spindle formation and cytokinesis.
43 st cortical localization of the ActBD during cytokinesis.
44 ion, and the stalled cells arrested prior to cytokinesis.
45 ow that KIF20B has a cell-autonomous role in cytokinesis.
46 on with Pom1 signaling for cell polarity and cytokinesis.
47 on modes promote the faithful progression of cytokinesis.
48 , and dimethylation of histone H3 in mitosis/cytokinesis.
49 during the metaphase-anaphase transition and cytokinesis.
50 a role in determining the cell shape during cytokinesis.
51 endent MT nucleation to complete mitosis and cytokinesis.
52 tsZ-ring structure and function in bacterial cytokinesis.
53 companied by binucleation through incomplete cytokinesis.
54 nectin) in promoting postnatal cardiomyocyte cytokinesis.
55 iad of deleterious stimuli, including failed cytokinesis.
56 h the existence of calcium transients during cytokinesis.
57 rtin and is required for its function during cytokinesis.
58 chromosome segregation, mitotic duration and cytokinesis.
59 ein attenuates p53 accumulation after failed cytokinesis.
60 2039 mutant was characterized by an impaired cytokinesis.
61 lls during cell division, a process known as cytokinesis.
62 quired for p53 accumulation following failed cytokinesis.
63 to the division site interdependently during cytokinesis.
64 wth in response to stimuli, including failed cytokinesis.
65 d cargo delivery at the division site during cytokinesis.
66 unding, a process which is key to successful cytokinesis.
67 tosis and increases back to G2 levels during cytokinesis.
68 via orienting the cell division axis during cytokinesis.
69 trates that function in polarized growth and cytokinesis.
70 hydrocytochalasin B [H2CB]) to induce failed cytokinesis.
71 Pxl1, thereby inhibiting Cdc15's function in cytokinesis.
72 Mso1 and Sec1 in membrane trafficking during cytokinesis.
73 nucleation from centrosomes and with ARF6 in cytokinesis.
74 not limit senescence associated with failed cytokinesis.
75 chment and facilitation of rapid mitosis and cytokinesis.
76 great attention is the protein regulator of cytokinesis 1, or Fascetto (Feo) in Drosophila, which fo
80 rol of cytoskeletal dynamics by dedicator of cytokinesis 2 (DOCK2), a hematopoietic cell-specific act
84 case of an adolescent boy with dedicator of cytokinesis 8 (DOCK8) deficiency, who experienced recurr
86 anscription 3 loss of function, dedicator of cytokinesis 8 deficiency, common variable immunodeficien
87 in two different and essential modes during cytokinesis: a motor activity-independent form that can
96 atase regulates microtubule dynamics in late cytokinesis and de-phosphorylates the kinesin component
97 omoted cardiomyocyte M-phase progression and cytokinesis and improved indicators of myocardial regene
98 e signaling pathway in controlling stem cell cytokinesis and in regulating stem cell behavior with ag
99 lciparum actin is implicated in endocytosis, cytokinesis and inheritance of the chloroplast-like orga
100 ing the site of cell cleavage is crucial for cytokinesis and involves precise activation of the RhoGE
102 function and the setup of the division site, cytokinesis and its spatial control remain an open-ended
104 oskeletal scaffolding protein that regulates cytokinesis and might promote tumorigenesis, in mice wit
107 emodeling of the division site for efficient cytokinesis and provide evidence that nodes serve to int
108 Interestingly, cells that did not complete cytokinesis and remained binucleated were found to be CD
109 ling cardiomyocytes fail to progress through cytokinesis and subsequently binucleate, consistent with
110 e glucose transporter GT1 and for successful cytokinesis and survival of infectious amastigote forms
111 dings demonstrate that VPS4A mutations cause cytokinesis and trafficking defects leading to a human d
112 uently, these cells stalled in metaphase and cytokinesis and ultimately underwent mitotic catastrophe
113 nonpermissive environment for cardiomyocyte cytokinesis and uncovered novel functions for the embryo
114 t the subpellicular complex is essential for cytokinesis and viability of disease-causing amastigotes
115 lthough cell cycle re-entry was unperturbed, cytokinesis and wound invasion were significantly compro
118 Finally, we explore emerging questions in cytokinesis, and discuss the role of extracellular matri
119 tin organization, chromosome segregation and cytokinesis, and induces an aberrant NE morphology in po
120 nd coordination between nuclear division and cytokinesis, and it is also important for infectious gro
121 CTCF in anaphase/telophase, transcription in cytokinesis, and long-range chromatin interactions in ea
124 panies various cellular processes, including cytokinesis, apoptosis, and cell migration, especially i
125 These data indicate that DNA separation and cytokinesis are coordinated in Sulfolobus, as is the cas
127 K), which has known functions in mitosis and cytokinesis, as induced in erythroblasts in an E2F-2-dep
129 To do this, they undergo a polarized form of cytokinesis at the apical membrane that is not well unde
131 for regulation of PP2A in cell polarity and cytokinesis because sds23Delta phenotypes were exacerbat
135 low cytometry, immunofluorescence and murine cytokinesis-block micronucleus assays confirmed the pres
136 and KHAP2 null mutants are unable to execute cytokinesis but are able to traffic GT1 to the flagellum
137 ntial for cleavage furrow positioning during cytokinesis, but the mechanisms by which MT-derived sign
138 ristoylated isoform is essential to complete cytokinesis by activating motility of the male flagellum
140 propose that ZapA and ZauP promote efficient cytokinesis by stabilizing the midcell Z-ring through a
142 uding regulation of cell shape and polarity, cytokinesis, cell migration, vesicle trafficking, and re
146 h in neoplastic cells undergoing mitosis and cytokinesis, consistent with their known roles in nonmus
147 o ZIKV infection, NS2B-NS3 expression led to cytokinesis defects and cell death in a protease activit
149 results in a decrease in vesicle fusion and cytokinesis defects such as slow ring constriction, defe
154 ein C (nudC), a key component of mitosis and cytokinesis during development, to be present in the inn
156 urrow (anaphase and telophase), and midbody (cytokinesis) during cell division in immortalized epithe
157 lar model reproduces hyperactive PI3K-driven cytokinesis failure and genome duplication and predicts
158 ideo microscopy, ATIP3 depletion exacerbates cytokinesis failure and mitotic death induced by low dos
160 / aneuploidy due to premature anaphase, and cytokinesis failure leading to genome duplication, depen
161 terzonal MTs, and several defects related to cytokinesis failure, including polyploidization of neura
168 urrounding cortex is regulated by the single cytokinesis formin CYK-1 and the ARP2/3 complex, which n
170 mitotic cardiomyocytes that fail to complete cytokinesis from those cells that undergo true cell divi
172 ssociated C1-FFLs controlling "regulation of cytokinesis," "G1/S transition of mitotic cell cycle," "
173 n already known as a key player in bacterial cytokinesis, had the "tubulin signature sequence" presen
178 ction of ECT2 with centralspindlin underlies cytokinesis in animal cells, solving a mechanistic conun
180 ation of an actomyosin ring is essential for cytokinesis in fission yeast, proper furrow formation al
182 ed from an hourglass to a double ring during cytokinesis in fungal and animal cells remains unknown.
184 l activation of this pathway restores normal cytokinesis in human Lowe syndrome cells and rescues OCR
186 Microtubules of the mitotic spindle direct cytokinesis in metazoans but this has not been documente
191 ts mammalian host and therefore suggest that cytokinesis in T. brucei could potentially be exploited
193 Our data corroborate the role of an impaired cytokinesis in the etiology of primary and syndromic mic
195 organizations of septin filaments throughout cytokinesis in vivo, providing mechanistic insights into
196 , we found several unexpected alterations to cytokinesis, including apical midbody migration in polar
197 ng to the central spindle is dispensable for cytokinesis, indicating that how PLK1 controls RhoA acti
198 phase of these oscillations is required for cytokinesis, indicating that oncogenic PI3K may directly
199 ns that function in polarized growth, and in cytokinesis inhibition in response to chromosome bridges
200 epletion of TbIAD5-1 and TbCentrin3 arrested cytokinesis initiation and disrupted the localization of
201 osome-specific proteins, including the three cytokinesis initiation factors CIF1, CIF2, and CIF3.
203 nsights into the flagellum motility-mediated cytokinesis initiation in the bloodstream form of T. bru
209 rmation of giant cells due to failed mitosis/cytokinesis is common in the blastomere stage of the pre
212 lieved that cleavage-furrow formation during cytokinesis is driven by the contraction of a ring conta
219 microtubule-rich structure that forms during cytokinesis, is a key regulator of abscission and appear
222 totic spindle to kinetochores, mitotic exit, cytokinesis, licensing of DNA replication by re-activati
223 s a complex with cyclin L1beta that, in late cytokinesis, localizes to the stem body, a structure in
225 moval predominates during the late stages of cytokinesis, mediated by both dynamin and the ESCRT (end
228 erently at earlier and later stages and in a cytokinesis mutant, Kif20b This mutant was previously sh
230 e novo formation of cell plates during plant cytokinesis, newly synthesized cell wall polysaccharides
232 Basic surface mutations mimic the effects on cytokinesis of loss of CYK4 cluster phosphorylation or i
234 nel, localizes to the cleavage furrow during cytokinesis of the fission yeast, Schizosaccharomyces po
235 tes spatial and temporal cues to ensure that cytokinesis only occurs after the genome has partitioned
239 us represent a novel regulatory mechanism of cytokinesis outcome in response to environmental cues.
240 osphorylated by Sid2 remains cortical during cytokinesis, over-accumulates in interphase nodes follow
242 These findings highlight the existence of a cytokinesis pathway in T. brucei that is different from
246 ing plays an essential role in orchestrating cytokinesis, precisely what its functions are and how th
247 assemble by Search-Capture-Pull-Release from cytokinesis precursor nodes that include the molecular m
248 oplasm and then segmentation, a synchronized cytokinesis, produces individual invasive daughters.
251 shortening of these overlaps at the onset of cytokinesis proved to be required to spatially confine m
252 g this signaling axis attenuated mitosis and cytokinesis, providing a new pathway for therapeutic dev
253 the function of these knock-in cell lines in cytokinesis, receptor degradation, and virus budding.
254 Together, these results identify two new cytokinesis regulators in T. brucei and integrate them i
258 e, which is essential for several aspects of cytokinesis, remains apically localized in each of these
262 nsically disordered protein localized to the cytokinesis site that is degraded upon septum completion
265 Our understanding of actomyosin ring-driven cytokinesis stems extensively from the fission yeast mod
267 ression of a non-cleavable Septin-2 restored cytokinesis, suggesting a direct mechanism of ZIKV-induc
268 resulted in multiple defects in mitosis and cytokinesis, supernumerary centrosomes, and compromised
269 re fibers are not obviously discernable, and cytokinesis takes place following the formation of elong
270 tional Kin1 substrates for cell polarity and cytokinesis (Tea4, Mod5, Cdc15, and Cyk3) were also phos
272 to the bud neck and form an hourglass before cytokinesis that acts as a scaffold for proteins involve
273 exemplifies alternate historical routes for cytokinesis that illustrate the range of eukaryotic dive
274 unknown type of contractile ring-independent cytokinesis that we termed wave-mediated cytofission.
276 Despite the importance of PtdIns(4,5)P(2) in cytokinesis, the regulation of this lipid in cell divisi
279 , suggesting that cFbs inhibit cardiomyocyte cytokinesis through ECM modulation rather than by secret
284 teins such as PRC1, the Protein Regulator of Cytokinesis, to ensure the correct separation of the two
285 gf1p (Rho1p GEF), participates in a delay of cytokinesis under cell wall stress (blankophor, BP).
286 scovered a system that blocks late events of cytokinesis until early ones are successfully accomplish
287 The Aurora B abscission checkpoint delays cytokinesis until resolution of DNA trapped in the cleav
291 nce of PLST-1, polarization was compromised, cytokinesis was delayed or failed, and 50% of embryos di
292 ify ECM proteins that modulate cardiomyocyte cytokinesis, we compared the composition of embryonic an
295 relies on proper coordination of mitosis and cytokinesis, where dynamic microtubules capture and fait
298 the late mitotic phase of the cell cycle and cytokinesis with SMILR knockdown resulting in ~10% incre
299 Aging disrupts the unique program of GSC cytokinesis, with GSCs failing to abscise from their dau
300 e for sorting live cardiomyocytes undergoing cytokinesis would provide a basis for future studies to