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2 the PRD is required for ALIX to function in cytokinetic abscission and retroviral budding, but not i
3 ncreases this postmitotic process and delays cytokinetic abscission by keeping the abscission checkpo
4 the absence of ESCRT function in C. elegans, cytokinetic abscission is delayed but can be completed,
6 ate quantitative imaging of ESCRT-III during cytokinetic abscission with biophysical properties of ES
9 ry plays an evolutionarily conserved role in cytokinetic abscission, the final step of cell division
19 e IQGAP-related protein Iqg1 (Cyk1) promotes cytokinetic actin ring formation and is required for cyt
21 and the EMTOC are critical for anchoring the cytokinetic actin ring to the medial region of the cell
22 pparatus determine the position at which the cytokinetic actomyosin array forms, but the molecular me
24 g protein, Rho1/RhoA plays a central role in cytokinetic actomyosin ring (CAR) assembly and cytokines
26 s regulatory proteins play a central role in cytokinetic actomyosin ring assembly and cytokinesis.
28 that did not constrict with actomyosin ring (cytokinetic actomyosin ring) invagination; instead, it s
35 l by which the central spindle organizes the cytokinetic apparatus is premised on an antiparallel arr
37 In plant cells, microtubules (MTs) in the cytokinetic apparatus phragmoplast exhibit an antiparall
38 We conclude that microtubules specify the cytokinetic apparatus via a dynamic zone of local RhoA a
39 lp1 out of the nucleolus, 2) maintaining the cytokinetic apparatus, and 3) halting the cell cycle unt
41 is in plant cells depends on guidance of the cytokinetic apparatus, the phragmoplast, to a cortical "
44 e our model to estimate the duration of post-cytokinetic attachment between a S.cerevisiae mother and
45 e specificity is unclear but could involve a cytokinetic birth scar that marks the newborn pole as th
47 two-pronged recruitment of ESCRT-III to the cytokinetic bridge and implicates ALIX in abscission che
48 c spindle function and the resolution of the cytokinetic bridge because its depletion resulted in spi
49 h KV mitotic cells strategically place their cytokinetic bridges at the rosette center, where Rab11-a
50 t KV-destined cells remain interconnected by cytokinetic bridges that position at the rosette's cente
52 tomyosin ring generates force to ingress the cytokinetic cleavage furrow in animal cells, yet its fil
53 We suggest that chromatin trapped in the cytokinetic cleavage furrow is the more likely reason fo
55 not localize to the interphase cortex or the cytokinetic cleavage furrow, whereas a 500-residue regio
56 on promotes filament reorientation along the cytokinetic cleavage furrow, which might have implicatio
58 omyces pombe proteins that contribute to the cytokinetic contractile ring accumulate during interphas
59 Our findings reveal how components of the cytokinetic contractile ring are reemployed during inter
60 proteins to test the popular model that the cytokinetic contractile ring assembles from a single myo
61 s centralspindlin activates ECT-2 to promote cytokinetic contractile ring formation, we show that the
62 that fission yeast assemble and constrict a cytokinetic contractile ring in a precisely timed, seque
65 o-dependent proteins control assembly of the cytokinetic contractile ring, yet it remains unclear how
74 processive elongation of actin filaments for cytokinetic contractile rings and other cellular structu
75 n yeast lacking Aip1 are viable and assemble cytokinetic contractile rings normally, but rings in the
76 regulators of the MEN, failed to remedy the cytokinetic defect of these mutants, indicating that Cdc
78 er-associated mutations results in increased cytokinetic defects but has no effect on BRCA2-dependent
79 d midzone formation can be restored, and the cytokinetic defects can be rescued in Kif4 esiRNA-treate
81 in cell plate formation are seedling lethal, cytokinetic defects in et2 predominantly occur in flower
82 use attenuation of MOR signaling rescued the cytokinetic defects of SIN mutants and allowed weak SIN
83 erations in cell wall formation, and similar cytokinetic defects were sporadically observed in other
87 -to-pole oscillation to help ensure that the cytokinetic division septum forms only at the mid-cell p
89 f metazoans, and the third gives rise to the cytokinetic dynamins of amoebozoans and plants and to ch
90 demonstrate that bcl-XS can have substantial cytokinetic effects under circumstances that produce rel
91 e we use cellularization, the first complete cytokinetic event in Drosophila embryos, to show that cl
92 he Drosophila embryo undergoes a large-scale cytokinetic event that packages thousands of syncytial n
97 1 is also required for the highly asymmetric cytokinetic events that extrude the two polar bodies dur
98 at recruit specific proteins and orchestrate cytokinetic events, such as sister nuclei being kept apa
104 cally, NMIIB-deficient spermatocytes exhibit cytokinetic failure in meiosis I, resulting in bi-nuclea
105 mentin mutant in T24 cultured cells leads to cytokinetic failure, resulting in binucleation (multinuc
108 N-triggered oligomeric switch that modulates cytokinetic formin function, revealing a novel mechanism
109 rcumferential ring structures that flank the cytokinetic FtsZ ring and appear to be associated with d
114 s are required for proper positioning of the cytokinetic furrow [1] [2], the role of pre-anaphase mic
116 ere is micron-scale curvature, including the cytokinetic furrow and the base of cell protrusions.
123 nd GEF-H1, LARG depletion does not result in cytokinetic furrow regression nor does it affect interna
124 Loss of Nm23-H1 in diploid cells leads to cytokinetic furrow regression, followed by cytokinesis f
132 vity in mammalian cells and demonstrate that cytokinetic furrowing is primarily regulated at the leve
133 yosin II in the cytokinetic ring, and faster cytokinetic furrowing, following depletion of GCK-1 or C
140 thought to provide the ingression force for cytokinetic furrows, but the role of membrane traffickin
143 protein initiates assembly of the bacterial cytokinetic machinery by polymerizing into a ring struct
145 evidence indicates that ZapA is part of the cytokinetic machinery of the cell and acts by promoting
147 ndomembrane vacuoles, mislocalization of the cytokinetic machinery, and extensive cortical membrane b
148 ocalization, microtubule biogenesis, and the cytokinetic machinery, as well as a substantial uncoupli
151 These PRC1-mediated modifications to the cytokinetic mechanism may be related to the specializati
152 essful cytokinesis in budding yeast, but new cytokinetic mechanisms can evolve through genetic change
155 ESCRT-III polymerization at the edge of the cytokinetic midbody structure, located at the center of
158 ition to localizing at the spindle poles and cytokinetic neck filaments, Cdc5 induces and localizes t
159 ddition to localization at spindle poles and cytokinetic neck filaments, Plk induces and localizes to
161 dies concluded that cells without Mid1p lack cytokinetic nodes and assemble rings unreliably from myo
165 eral kinases appear early in G2, mature into cytokinetic nodes by adding anillin Mid1p, myosin-II, fo
167 n Deltamid1 cells that Cdc12p accumulates in cytokinetic nodes scattered in the cortex and produces a
169 g and de novo assembly of the plant-specific cytokinetic organelle, the cell plate, which develops ac
172 ediated lethality could not be attributed to cytokinetic perturbations, nor did ara-CTP formation or
173 nd other drugs, we showed that exit from the cytokinetic phase of the cell cycle depends on ubiquitin
174 either cyk3 or hof1 alone results in a mild cytokinetic phenotype [5-7], but deletion of both genes
177 itosis, and relocates to the recently formed cytokinetic plane, where it establishes a fully polarize
186 as a mechanical scaffold that recruits other cytokinetic proteins to establish functional divisomes.
187 Chk1 in mitotic mammalian cells resulted in cytokinetic regression and binucleation, increased chrom
189 s-Galbraith and colleagues report that a key cytokinetic regulator in fission yeast, Cdc15, is phosph
190 factor ECT2, an orthologue of the Drosophila cytokinetic regulator Pebble, providing a direct means f
195 We propose that the most active form of the cytokinetic RhoGEF involves complex formation between EC
196 ide using a contractile apparatus called the cytokinetic ring (CR) that associates dynamically with t
198 FtsA are recruited independently to the FtsZ cytokinetic ring (Z ring) and are essential for cell div
202 tile ring assembly in vivo.The fission yeast cytokinetic ring assembles by Search-Capture-Pull-Releas
205 l player in the cytoskeletal family, forms a cytokinetic ring at mid-cell, and recruits the division
207 that the amidases require activation at the cytokinetic ring by proteins with LytM domains, of which
213 cles through contraction and relaxation, the cytokinetic ring disassembles during contraction through
214 es of FtsZ, a bacterial protein that forms a cytokinetic ring during cell division, are essential for
217 B, but not delta N592, were localized to the cytokinetic ring during mitosis, indicating that, in ver
218 mbly and in maintaining the integrity of the cytokinetic ring during the early stages of division.
219 nt tubulin homolog, FtsZ, for assembling the cytokinetic ring essential for cell division, but are ot
224 he localization of Tol-Pal components to the cytokinetic ring in Escherichia coli has led to the prop
225 n-related protein Mid1 does not position the cytokinetic ring in the fission yeast Schizosaccharomyce
226 esis is the assembly of a stable but dynamic cytokinetic ring made up of the essential tubulin homolo
228 Pom1 restricts to the cell middle cortical cytokinetic ring precursor nodes organized by the SAD-li
229 is high, which ensures proper positioning of cytokinetic ring precursors at the cell geometrical cent
230 s, first promotes the medial localization of cytokinetic ring precursors organized by the SAD kinase
231 tly disrupt the assembly or stability of the cytokinetic ring protein FtsZ, nor does it affect the re
232 tubulins, is a GTPase that assembles into a cytokinetic ring structure essential for cell division i
233 its bacterial homologue FtsZ establishes the cytokinetic ring that constricts during cell division.
234 -like FtsZ GTPase into a membrane-associated cytokinetic ring that defines the division plane in bact
235 ess fibers (SFs), muscle sarcomeres, and the cytokinetic ring to both generate and sense mechanical f
236 orescent phalloidin into the medium, and the cytokinetic ring was disrupted after injection of the my
237 ordinates assembly and placement of the FtsZ cytokinetic ring with bipolar localization of the newly
238 multinucleate cells, failure to maintain the cytokinetic ring, and compromised SPB association of the
239 to perform two functions: stabilize the FtsZ cytokinetic ring, and facilitate septal peptidoglycan sy
240 vity, anillin and nonmuscle myosin II in the cytokinetic ring, and faster cytokinetic furrowing, foll
241 ssential for ensuring proper assembly of the cytokinetic ring, and its deletion leads to mis-localiza
242 Cytokinesis in bacteria is mediated by a cytokinetic ring, termed the Z ring, which forms a scaff
243 recruited by active RhoA and anillin to the cytokinetic ring, where they in turn limit RhoA activity
244 pombe, cytokinesis also involves a conserved cytokinetic ring, which has been generally assumed to pr
262 dge stability by anillins, key regulators of cytokinetic rings and cytoplasmic bridges [1, 4-7].
264 adoxically, proteins that promote closure of cytokinetic rings are enriched on stably open intercellu
266 ity of myo2-E1-Sup1 cells depend on the late cytokinetic S. pombe myosin II isoform, Myp2p, a non-ess
267 nvestigate the F-BAR domain of the essential cytokinetic scaffold, Schizosaccharomyces pombe Cdc15, d
271 ses, the cell assembles essentially the same cytokinetic signaling ensemble-opposed astral microtubul
273 e polar and new static complexes form at pre-cytokinetic sites, ensuring positioning at the new pole
276 es have noted important distinctions between cytokinetic structures in dividing cells and muscle sarc
277 cates from the pericentrosomal region to key cytokinetic structures including the cleavage furrow, an
278 transitional hourglass that pre-patterns two cytokinetic structures-a septin double ring and an actom
281 tes the DivJ kinase and directly acts on the cytokinetic tubulin, FtsZ, to tune cytokinesis with the
282 ial tubulin homolog required to assemble the cytokinetic Z ring and recruit the components of the div
283 n Escherichia coli, precise placement of the cytokinetic Z ring at midcell requires the concerted act
286 gulatory system that limits formation of the cytokinetic Z ring to midcell by preventing its formatio
287 local negative control over assembly of the cytokinetic Z ring to prevent potential cutting of the c
288 n-like FtsZ protein, helping to assemble the cytokinetic Z ring, anchor it to the cytoplasmic membran
289 inD is involved in spatial regulation of the cytokinetic Z ring, and ParAs are involved in chromosome
290 ght about by a change in the location of the cytokinetic Z ring, which is composed of the tubulin-lik
296 GTPase FtsZ assemble at midcell to form the cytokinetic Z-ring, which coordinates peptidoglycan (PG)
300 symmetric division involves the formation of cytokinetic Z-rings near both poles of the developing ce