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1 nistic interaction of the hormones auxin and cytokinin.
2 hormones, including auxin, strigolactone and cytokinin.
3 actors that are transcriptionally induced by cytokinin.
4 ed with changes in localization of auxin and cytokinin.
5 oots and which has previously been linked to cytokinin.
6 he production of chlorophyll are enhanced by cytokinin.
7 are transcriptionally induced in response to cytokinin.
8 involved in the response to the phytohormone cytokinin.
9 ype-A ARR proteins, and are hyposensitive to cytokinin.
10 a subset of the transcriptional response to cytokinin.
11 transport of Zn were strictly controlled by cytokinins.
12 tory processes, including those activated by cytokinins.
13 athways of auxin, brassinosteroids (BRs) and cytokinins.
14 feedback loop between class I KNOX genes and cytokinin [2, 3], and class I KNOX expression is a conse
15 sic acid (ABA), three auxin catabolites, and cytokinins (26 isoprenoid and four aromatic) in response
16 bioregulators include auxins, gibberellins, cytokinins, abscisic acid, brassinosteroids, polyamines,
17 lain some of the adverse effects of elevated cytokinin action on plant development and stress physiol
18 LRC cells depends on PIN-FORMED 5 (PIN5), a cytokinin-activated intracellular transporter that pumps
19 evated amounts of indole acetic acid, active cytokinins, active gibberellin, and salicylic acid were
20 e dark through the manipulation of auxin and cytokinin activity as well as through the activation of
22 the combination of simple synthesis, lowered cytokinin activity, and enhanced inhibitory effects on C
26 While the receptors are central regulators, cytokinin also is accumulated during early phases of sym
28 ahp6 mutants are hypersensitive to exogenous cytokinin and 1-napthylphthalamic acid (NPA), highlighti
29 ects; and the interplay among ABA, ethylene, cytokinin and auxin is tissue-specific, as evidenced by
30 In summary, these mechanisms self-regulate cytokinin and auxin signaling domains, ensuring correct
31 , we show here that two major phytohormones, cytokinin and auxin, display different yet partially ove
33 the control of ARR10 and AUX1 expression by cytokinin and auxin, this circuit potentially functionin
34 he local modulation of cellular responses to cytokinin and auxin, two key phytohormones regulating ce
36 involved in chromatin remodeling activities, cytokinin and cell cycle regulation and cellular respira
40 d a genetic approach to evaluate the role of cytokinin and its signaling pathway in the light-induced
51 or establishing how crosstalk between auxin, cytokinin, and ethylene regulates patterning in root dev
55 ress as a negative regulator to control this cytokinin-associated module of CRF6-dependent genes and
57 wth such as jasmonic acid, brassinosteroids, cytokinins, auxin and synthesis of flavonoid, phenylprop
58 ocusing on the earliest stages, we propose a cytokinin-auxin feedback model during early gynoecium pa
60 ins emulate the structural changes caused by cytokinin binding, resulting in domain motion propagatin
63 ajor contributors to this process, promoting cytokinin biosynthesis but repressing gibberellin produc
64 abidopsis, class I KNOX activity can promote cytokinin biosynthesis by an ISOPENTENYL TRANSFERASE gen
67 r responsiveness of these genes confirm that cytokinin biosynthesis is a key target of the common sym
70 ed distinct differences in the expression of cytokinin biosynthesis, catabolism and signaling genes i
72 lation, we followed transcript levels of the cytokinin biosynthetic pathway genes in a sliding develo
73 orter transgenic line further suggested that cytokinin blocks the re-establishment of auxin gradients
77 xtension, and PpIPT3 and exogenously applied cytokinin can partially compensate for loss of class I K
79 t target genes involved in the final step of cytokinin (CK) biosynthesis, LONELY GUY3 (LOG3) and LOG4
80 Strikingly, early epidermal activation of cytokinin (CK) pathways was indicated, based on the indu
81 uppress gibberellin signaling and to promote cytokinin (CK) responses, its catalytic OGT activity was
84 ature, causes severe depletion of endogenous cytokinins (CKs) in the model plant Arabidopsis (Arabido
87 , in addition to showing an elevated cambial cytokinin content and signaling level, the cambial auxin
88 er (TCSn::GFP) closely matches intracellular cytokinin content in roots, yet we also find cytokinins
91 hese findings show that metabolic control of cytokinin could provide the key to breeding Zn-enriched
92 dependent upon cytokinin signaling and that cytokinins could activate glutaredoxin gene expression i
94 in P. patens is underpinned by complex auxin-cytokinin crosstalk that is regulated, at least in part,
95 the AHK2 and AHK3 genes, named repressor of cytokinin deficiency2 (rock2) and rock3, respectively.
97 In addition, crosses between "long-root" cytokinin-deficient plants and "long-root" glutaredoxin-
98 metabolism by root-specific expression of a cytokinin degradation enzyme was able to improve both Zn
102 ambium cell divisions without inducing other cytokinin-dependent effects such as the inhibition of va
106 rs of HEMA1 and LHCB6 genes, indicating that cytokinin-dependent transcription factors directly regul
108 ation system, we demonstrated that auxin and cytokinin differentially regulate phloem and cambium reg
110 sults confirmed that complementary auxin and cytokinin domains are required for phloem and cambium re
111 t branching by elevating contents of GA3 and cytokinins due to upregulated transcript levels of sever
112 tified as a direct target of ARR10, with its cytokinin-enhanced expression resulting in enhanced shoo
116 cies, we conducted a comparative analysis of cytokinin genes in response to the beet cyst nematode (B
117 standing of the metabolism and perception of cytokinin has made great strides in recent years, mostly
119 c lines to provide unequivocal evidence that cytokinins have a key role in controlling Zn status in p
120 R/Cas9-based approach to disrupt a subset of cytokinin histidine kinase (HK) receptors in rice (Oryza
124 e CRFs results in partially insensitivity to cytokinin in a root elongation assay and affects the bas
125 Previous studies have suggested a role for cytokinin in feeding site formation induced by these two
126 f CKX3 on the positive and negative roles of cytokinin in nodule development, infection and regulatio
127 re generated and used to clarify the role of cytokinin in regulation of various physiological respons
128 est that AtGRXS3/4/5/8 operate downstream of cytokinins in a signal transduction pathway that negativ
130 diminished TCSn::GFP response to immobilised cytokinins in cytokinin receptor mutants, further indica
131 cytokinin content in roots, yet we also find cytokinins in extracellular fluid, potentially enabling
132 and, thereby, determines the degradation of cytokinins in natural Arabidopsis thaliana accessions.
133 n and trans-zeatin riboside (the most active cytokinins) in TMB-treated seeds might be responsible fo
134 the receiver domain of the histidine kinase CYTOKININ-INDEPENDENT 1 (CKI1RD) from Arabidopsis thalia
135 e for spatiotemporally correct expression of CYTOKININ INDEPENDENT1 (CKI1), encoding the constitutive
136 haracterization of an auxin deficient mutant cytokinin induced root curling 2 (ckrc2) in this work re
137 ate that the initiation of decapitation- and cytokinin-induced axillary bud outgrowth is independent
141 s of the ribosomal protein L4 encoded by the cytokinin-inducible genes RPL4A and RPL4D, and that RPL4
145 ic elements in a regulatory network by which cytokinin inhibits root cell elongation in concert with
149 ssary and sufficient for nodulation, whereas cytokinin is antagonistic to lateral root development, w
150 the classical functions of the plant hormone cytokinin is the regulation of plastid development, but
151 nscriptionally regulated by the phytohormone cytokinin, is necessary for the ability of cytokinin to
153 have also shown that direct manipulation of cytokinin levels in transgenic plants has dramatic effec
155 kinin levels are low in bp, but fsh restores cytokinin levels to near normal by activating cytokinin
156 eptor AHK2 and is characterized by increased cytokinin levels, downregulation of cytokinin signaling
159 at mycorrhization and Pi fertilization share cytokinin-mediated improved shoot growth, whereas enhanc
160 SA acid to affect immunity, instead altering cytokinin-mediated regulation of downstream components.
167 oem prior to continuous cambium restoration, cytokinin only promotes the formation of new phloem, not
169 and reveal that signal peptide processing of Cytokinin Oxidase 2 (CKX2) affects its enzymatic activit
170 Here, we show that the Lotus japonicus Ckx3 cytokinin oxidase/dehydrogenase gene is induced by Nod f
171 ncoding calcium-dependent protein kinase and cytokinin oxidase/dehydrogenase were significantly assoc
174 ely overlooked link between the ethylene and cytokinin pathways, which acts through a phosphorelay me
175 tion in the actively dividing cambial cells, cytokinins peak in the developing phloem tissue of a Pop
176 the endoplasmic reticulum, cellular sites of cytokinin perception and importance of spatially heterog
180 ing involves regulation of the expression of cytokinin primary response genes by type-B response regu
181 RESPONSE REGULATORs (ARRs) that mediate the cytokinin primary response, making use of chromatin immu
182 thereby defining a crucial link between the cytokinin primary-response pathway and the transcription
183 ipts was a set of five genes associated with cytokinin processes: (signaling) ARR6, ARR9, ARR11, (bio
186 allus production in this mutant requires the cytokinin receptor AHK2 and is characterized by increase
187 n::GFP response to immobilised cytokinins in cytokinin receptor mutants, further indicate that recept
190 psis thaliana were used to study the role of cytokinin receptors in the expression of chloroplast gen
191 ines revealed contrasting differences in the cytokinin receptors mediating cell cycle activation in f
192 signaling intermediates acting downstream of cytokinin receptors, further substantiating the role of
193 ese results indicate that HK5 and HK6 act as cytokinin receptors, with overlapping functions to regul
194 on of endoreduplication cycles linked to the cytokinin-regulated Cell Cycle Switch 52A (Mt CCS52A) ge
195 basal expression of a significant number of cytokinin-regulated genes, including the type-A ARRs, al
196 n 11 (MtENOD11) infection marker, and of the cytokinin-regulated Nodulation Signaling Pathway 2 (Mt N
197 TOB1 transport of IBA into the vacuole, and cytokinin-regulated TOB1 expression provide a mechanism
198 l primordium and strengthen the concept that cytokinin regulates auxin homeostasis during gynoecium d
200 of type-B ARR activation, and basis by which cytokinin regulates diverse aspects of growth and develo
203 n and ethylene, and support a model in which cytokinin regulates shootward auxin transport to control
204 , thereby, increased seed yield suggest that cytokinin regulates various aspects of reproductive grow
206 y, while the upregulation of a Y allele of a cytokinin regulator (APRT3) may cause female sterility.
208 the results suggest that a pre-existing KNOX-cytokinin regulatory module was recruited into vascular
216 mily of plant transcription factors known as Cytokinin Response Factors (CRFs) were examined for cons
218 ociations characterized the growth-promoting cytokinin response regulator ARR1, and the wood developm
220 hk6 mutant also exhibited a severely reduced cytokinin response, consistent with the developmental ph
221 al role of the type-B ARRs in regulating the cytokinin response, mechanism of type-B ARR activation,
223 tive CKs in roots and negatively impacts the Cytokinin Response1 (CRE1)-dependent NF activation of a
224 increase the cZ : tZ ratio to maintain basal cytokinin responses and allocate Pi in the root system t
225 responses increase under osmotic stress, but cytokinin responses are only slightly reduced; inhibitio
226 er AUX1 functions as a positive regulator of cytokinin responses in the root; mutation of AUX1 specif
228 ana) Cytokinin Response Factor 6 (CRF6) is a cytokinin-responsive AP2/ERF-family transcription factor
229 his, together with the identification of the cytokinin-responsive elements in the NIN promoter, stron
230 LISM-INVOLVED (GNC) and its paralog GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1 (GNL), have already be
231 LE, CARBON METABOLISM-INVOLVED) and GNC-LIKE/CYTOKININ-RESPONSIVE GATA FACTOR1 as well as that of SPC
232 Here, we describe the identification of the cytokinin-responsive NO GAMETOPHORES 2 (PpNOG2) gene, wh
234 show that boundary formation is dependent on cytokinin's control on auxin polar transport and degrada
235 ly increased amounts of active gibberellins, cytokinins, salicylic acid, and jasmonate compared with
236 utophagy, demonstrating that plants modulate cytokinin sensitivity through autophagic regulation of t
237 with misregulation of MSP signaling, changed cytokinin sensitivity, and developmental aberrations tha
240 f the cytokinin response using the synthetic cytokinin sensor, TCSn, showed that this response occurs
241 In Arabidopsis (Arabidopsis thaliana), the cytokinin signal is perceived by three membrane-located
242 Here, we describe a mechanistic link between cytokinin signaling and autophagy, demonstrating that pl
243 TOB1 expression provide a mechanism linking cytokinin signaling and IBA contribution to the auxin po
244 taredoxin gene expression was dependent upon cytokinin signaling and that cytokinins could activate g
246 engage ethylene with salicylic acid (SA) and cytokinin signaling during plant response to nematode in
247 To explore the functional significance of cytokinin signaling for cambial development, we engineer
254 shown the requirement for receptor-mediated cytokinin signaling in symbiotic nodule organogenesis.
255 that TEM also acts as a link between GA and cytokinin signaling in the epidermis by negatively regul
256 hat NIN expression is initially triggered by cytokinin signaling in the pericycle to initiate nodule
257 ncreased cytokinin levels, downregulation of cytokinin signaling inhibitors ARR7 and ARR15, and induc
261 esults demonstrate an important role for the cytokinin signaling pathway in chloroplast development,
262 on by CKI1 likely involves activation of the cytokinin signaling pathway mediated by histidine phosph
263 amily transcription factor that, through the cytokinin signaling pathway, plays a key role in the inh
265 symbiotic nodule development in legumes, and cytokinin signaling responses occur locally in nodule pr
267 tors (type-A ARR) are negative regulators of cytokinin signaling that are transcriptionally induced i
281 ene signaling controls MSP responsiveness to cytokinin specifically in the root transition zone, pres
282 o circadian stress regimes requires a normal cytokinin status which, acting primarily through the AHK
283 e genes was correlated with higher levels of cytokinin/sugar signaling in growing buds of wild-type p
284 r with the rapid repression of both genes by cytokinin, this indicates that LjIpt2 and LjLog4 contrib
285 e cytokinin, is necessary for the ability of cytokinin to exert inhibitory effects on lateral root pr
286 of AUX1 specifically affects the ability of cytokinin to inhibit cell elongation but not cell prolif
287 ssing, while, control water presented mainly cytokinin trans-zeatin riboside, procyanidin dimer, caff
288 d brassinosteroid genes, and upregulation of cytokinin transport/signaling genes, from 1,023 differen
290 R(1) significantly enhanced total isoprenoid cytokinins under dark conditions in comparison with othe
291 controlling the position of the TZ [9, 10]. Cytokinin via the ARABIDOPSIS RESPONSE REGULATOR 1 (ARR1
292 f ARR10, Arabidopsis lines hypersensitive to cytokinin were generated and used to clarify the role of
293 s of abscisic acid and aphid feeding-induced cytokinins were accumulated in the SCA-tolerant sorghum
295 eat regeneration in the absence of exogenous cytokinins, which facilitates selection of transgenic pl
296 Forchlorfenuron (FCF) is a synthetic plant cytokinin widely used in agriculture to promote fruit si
298 ulatory circuits controlling interactions of cytokinin with auxin and ethylene, and support a model i