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1 bacterium that grows and replicates inside a cytoplasmic inclusion.
2 uesters, wild-type TDP-43 within nuclear and cytoplasmic inclusions.
3 from brain tissue rich in neuronal and glial cytoplasmic inclusions.
4 ial cellular mechanism for the resorption of cytoplasmic inclusions.
5 inclusions and neurites and unusual striatal cytoplasmic inclusions.
6 wild type and R239C mutant human GFAP led to cytoplasmic inclusions.
7 he cytoskeleton and the ensuing formation of cytoplasmic inclusions.
8 minal fragments of mutant htt in nuclear and cytoplasmic inclusions.
9 ercentage of cells that contain eosinophilic cytoplasmic inclusions.
10 ic degeneration and alpha-synuclein-positive cytoplasmic inclusions.
11 optotic death and formation of ubiquitinated cytoplasmic inclusions.
12 leaved huntingtin fragments form nuclear and cytoplasmic inclusions.
13 es, and microglia all develop characteristic cytoplasmic inclusions.
14 oth electron-dense intranuclear deposits and cytoplasmic inclusions.
15 ll survival but did not diminish nuclear and cytoplasmic inclusions.
16 inding to FUS and decreased the formation of cytoplasmic inclusions.
17 ggregates in oligodendrocytes, forming glial cytoplasmic inclusions.
18 utonomic nuclei, and with argyrophilic glial cytoplasmic inclusions.
19 of multiple system atrophy, including glial cytoplasmic inclusions.
20 43 constitutes a major component of aberrant cytoplasmic inclusions.
21 ad to the accumulation of the FUS protein in cytoplasmic inclusions.
22 distinguish seeds from Lewy bodies and glial cytoplasmic inclusions.
23 ominent vesicle clustering, leading to round cytoplasmic inclusions.
24 inducing ALS pathogenesis, the formation of cytoplasmic inclusions.
25 Notably, TDP-43 was also recruited to these cytoplasmic inclusions.
26 tant or wild-type (WT) FUS can form neuronal cytoplasmic inclusions.
27 und intracellular phenotype defined by large cytoplasmic inclusions.
28 ytoplasm and dendrites without forming large cytoplasmic inclusions.
29 sclerosis with abnormal podocytes containing cytoplasmic inclusions.
30 ical conditions, which is different from the cytoplasmic inclusions.
31 inor matrix protein VP24 were distributed in cytoplasmic inclusions.
32 ength-dependent manner and co-localises with cytoplasmic inclusions.
33 hoprotein/ppUL32), that accumulates within a cytoplasmic inclusion adjacent to the nucleus at late ti
34 have ubiquitin (ub)-immunoreactive neuronal cytoplasmic inclusions and characteristic lentiform ub-i
37 gnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurologic
40 d ubiquitin-immunoreactive (UBQ-ir) neuronal cytoplasmic inclusions and neurites, and in some familia
41 with FUS mutations showed FUS-immunoreactive cytoplasmic inclusions and predominantly lower motor neu
42 muscle disorder characterized by nuclear and cytoplasmic inclusions and vacuolation of muscle fibers.
43 eal dystrophic changes, rimmed vacuoles with cytoplasmic inclusions, and focal disorganization of myo
45 htt), formation of neuronal intranuclear and cytoplasmic inclusions, and neuronal dysfunction/degener
46 eurites, short dystrophic neurites, neuronal cytoplasmic inclusions, and neuronal loss and gliosis us
49 tein 43 (TDP-43, encoded by TARDBP) neuronal cytoplasmic inclusions are the pathological hallmark in
51 kDa sarkosyl-insoluble fragment and globular cytoplasmic inclusions, as detected by an antibody speci
52 The 126-kDa protein formed numerous large cytoplasmic inclusions associated with microfilaments, w
54 cteristic that during their infection cycle, cytoplasmic inclusion bodies (IBs) are formed where comp
56 iruses characteristically form membrane-less cytoplasmic inclusion bodies (IBs) wherein RNA replicati
59 e, whereas the mutant protein accumulates in cytoplasmic inclusion bodies and does not reach the memb
60 uently found that P6-GFP forms highly motile cytoplasmic inclusion bodies and revealed through fluore
61 nd lysosomes are recruited to pericentriolar cytoplasmic inclusion bodies by a process requiring an i
63 he mammalian orthoreovirus life cycle within cytoplasmic inclusion bodies compartmentalizes viral rep
64 nal degeneration with Lewy bodies, which are cytoplasmic inclusion bodies containing deposits of aggr
67 nal protein known to be a major component of cytoplasmic inclusion bodies formed during CaMV infectio
68 FP, this perinuclear compartment consists of cytoplasmic inclusion bodies generated in response to th
70 er inflamed tissues and that Ag localized to cytoplasmic inclusion bodies in the acute KD ciliated br
71 s that bind to acute KD tissues detect Ag in cytoplasmic inclusion bodies in the acute KD ciliated br
72 f aggregated protein into neurofilament-rich cytoplasmic inclusion bodies is a common cytopathologica
73 r of cytoplasmic replicating viruses produce cytoplasmic inclusion bodies or protein aggregates; howe
75 saki disease-associated antigen localizes to cytoplasmic inclusion bodies that are consistent with ag
76 IHC with synthetic KD antibodies resides in cytoplasmic inclusion bodies that are consistent with ag
77 Q, mice expressing N586-82Q accumulate large cytoplasmic inclusion bodies that can be visualized with
78 es are believed to replicate in distinctive, cytoplasmic inclusion bodies, commonly called viral fact
80 ion and assembly are thought to occur within cytoplasmic inclusion bodies, which we call viral factor
85 he existence of Lewy bodies, an eosinophilic cytoplasmic inclusion body, distributed diffusely throug
86 d to date, we provide evidence that neuronal cytoplasmic inclusion burden in the hippocampus and para
87 Z-DEVD-FMK significantly reduced nuclear and cytoplasmic inclusions but did not increase survival.
89 riant 1 isolate MN-61-2 in ISE6 cells showed cytoplasmic inclusions characteristic of A. phagocytophi
91 n is a component of Lewy bodies, the fibrous cytoplasmic inclusions characteristic of nigral dopamine
94 e neuropathological hallmark of MSA is glial cytoplasmic inclusions consisting of filaments of alpha-
95 imarily cleaved N-terminal products, whereas cytoplasmic inclusions contained cleaved and larger inta
96 ctural hallmarks seen in patients, including cytoplasmic inclusions containing aberrant proteinaceous
97 019) and Mann et al. (2019) demonstrate that cytoplasmic inclusions containing aggregated phosphoryla
99 aracterized by the presence of Lewy bodies - cytoplasmic inclusions containing alpha-synuclein protei
101 ple system atrophy is characterized by glial cytoplasmic inclusions containing filamentous alpha-synu
104 racterized by macroautophagy marker-positive cytoplasmic inclusions containing mainly mitochondrial r
106 pyramidal tracts and included fine, diffuse cytoplasmic inclusions containing phospho-alpha-synuclei
107 nts are characterized by the accumulation of cytoplasmic inclusions containing phosphorylated and tru
112 d mutations in FUS, whereas in FTLD-FUS, the cytoplasmic inclusions do not contain mutant FUS, sugges
113 itive pathology, including frequent neuronal cytoplasmic inclusions, dystrophic neurites in both grey
114 However, CTFs rapidly aggregated into stable cytoplasmic inclusions following de novo cleavage when d
115 repeat in Drosophila results in nuclear and cytoplasmic inclusion formation, and cellular degenerati
116 We show that sympathetic neurons containing cytoplasmic inclusions formed by 97 glutamines expressed
117 sed laser capture microdissection to isolate cytoplasmic inclusions from skeletal muscle from a patie
118 gical hallmark is the oligodendrocytic glial cytoplasmic inclusion (GCI) consisting of alpha-synuclei
120 as the frequency of glial (oligodendroglial) cytoplasmic inclusions (GCIs) and neuronal cytoplasmic i
121 , but not beta- or gamma-synuclein, in glial cytoplasmic inclusions (GCIs) throughout the MSA brain.
122 GFAP immunoreactivity and presence of glial cytoplasmic inclusions (GCIs) were assessed in the ArcN.
123 odegenerative disease characterised by glial cytoplasmic inclusions (GCIs), containing alpha-synuclei
124 facilitate vacuolar clearance of nuclear and cytoplasmic inclusions highlights the role of cellular a
126 The discovery of alpha-internexin in the cytoplasmic inclusions implicates novel mechanisms of pa
127 ted the presence of alpha-synuclein-positive cytoplasmic inclusions in 8% of tTGase-expressing cells.
129 e numbers of compact, granular or skein-like cytoplasmic inclusions in all fused in sarcoma-positive
130 s a DNA/RNA-binding protein (RBP) that forms cytoplasmic inclusions in ALS and frontotemporal lobular
132 o stress granules and drive the formation of cytoplasmic inclusions in animal models that recapitulat
133 disease is the presence of Rosenthal fibers, cytoplasmic inclusions in astrocytes that contain the in
134 the pathological features of nuclear and/or cytoplasmic inclusions in astrocytes, Bergmann glia, and
136 ologically phosphorylated and accumulates in cytoplasmic inclusions in both neurons and glia of affec
137 I alpha and beta subunits are present within cytoplasmic inclusions in cells that overexpress synphil
138 Muscle fibers with hyaline desmin-containing cytoplasmic inclusions in combination with focal myopath
139 ribution of dystrophic neurites and neuronal cytoplasmic inclusions in cortex and hippocampus compare
140 hey are normally localized, and found within cytoplasmic inclusions in degenerating regions of affect
142 of TDP-43 and its associated deposition into cytoplasmic inclusions in different areas of the central
144 d that transthyretin accumulates with TDP-43 cytoplasmic inclusions in frontal temporal lobar degener
145 he ER in wild-type plants but accumulated as cytoplasmic inclusions in get1, get3, or get4 mutants.
147 AR DNA-binding protein-43 positive) neuronal cytoplasmic inclusions in hippocampus and cerebellum wer
148 mis-localization of RACK1 on TDP-43 positive cytoplasmic inclusions in motor neurons of ALS patients.
149 umulation of mitochondria in TDP-43-negative cytoplasmic inclusions in motor neurons, lack of mitocho
152 king findings were 1) eosinophilic, rod-like cytoplasmic inclusions in neocortical and thalamic neuro
155 RBM45 is an RNA-binding protein that forms cytoplasmic inclusions in neurons and glia in ALS and FT
158 has been identified as a major component of cytoplasmic inclusions in patients with sporadic ALS; ho
159 er-insoluble cell fractions and formed round cytoplasmic inclusions in primary cortical neurons.
160 disordered C terminus, have been observed in cytoplasmic inclusions in sporadic amyotrophic lateral s
161 rotein SRRM2 is sequestered into the poly-GR cytoplasmic inclusions in the C9-FTD/ALS mouse model and
162 0th among RRM-bearing prion candidates, form cytoplasmic inclusions in the degenerating motor neurons
163 isease duration-related increase in neuronal cytoplasmic inclusions in the dentate gyrus and cornu am
164 tical dysfunction: n = 12) had more neuronal cytoplasmic inclusions in the dentate gyrus, cornu ammon
165 e, tau and alpha-synuclein-negative neuronal cytoplasmic inclusions in the frontotemporal cortex and
168 accompanied by the pathological hallmark of cytoplasmic inclusions in the neurodegenerative diseases
169 rther investigated whether neuronal or glial cytoplasmic inclusions in the prefrontal, temporal and c
171 r human red/green opsins, aggregated to form cytoplasmic inclusions in transfected cells, which may e
173 lear RNA-binding protein that forms neuronal cytoplasmic inclusions in two major neurodegenerative di
174 uclein and ubiquitin-positive, eosinophilic, cytoplasmic inclusions) in many of the surviving neurons
175 duction of proteasome activity, formation of cytoplasmic inclusions increased significantly in HEK293
176 assembly of stress granules (SGs), discrete cytoplasmic inclusions into which stalled translation in
177 olded protein aggregates into ubiquitin-rich cytoplasmic inclusions is linked to the pathogenesis of
178 TAR DNA-binding protein 43 (TDP-43) as toxic cytoplasmic inclusions is one of the hallmarks of these
182 verity of fused in sarcoma-positive neuronal cytoplasmic inclusions, neuronal intranuclear inclusions
183 short and long dystrophic neurites, neuronal cytoplasmic inclusions, neuronal loss and gliosis and th
185 liver disorders and share similarities with cytoplasmic inclusions observed in neural diseases and m
186 ne the dynamics and structure of nuclear and cytoplasmic inclusions of atrophin-1, implicated in dent
187 ximal tubulopathy (LCPT) is characterized by cytoplasmic inclusions of monoclonal LC within proximal
188 n microscopy of dentate gyrus neurons showed cytoplasmic inclusions of paired helical filaments, P-ta
189 The majority of patients show ubiquitinated cytoplasmic inclusions of TAR DNA binding protein of 43
190 le, propagation of abnormally phosphorylated cytoplasmic inclusions of TAR-DNA-Binding protein (TDP-4
191 Hallmarks of both FTLD and ALS are the toxic cytoplasmic inclusions of the prion-like C-terminal frag
193 a through a shared pathological signature of cytoplasmic inclusions of the ubiquitinated protein TDP-
194 atures of OPMD, namely ptosis, dysphagia and cytoplasmic inclusions on muscle biopsy, although with s
195 uscle resulted in progressive, age-dependent cytoplasmic inclusion pathology, as observed in humans w
196 europathological findings, GCIs and neuronal cytoplasmic inclusions play an important role in clinico
197 stributed, often in Ubiquitin-immunoreactive cytoplasmic inclusions predominantly located basally in
198 e potential for aggregation and formation of cytoplasmic inclusions raises the possibility that Stat5
199 W122S mutation, mutant mice did not manifest cytoplasmic inclusions (reducing bodies) in muscle.
200 ntly recruited endogenous TDP-43, and formed cytoplasmic inclusions reminiscent of ALS/FTD pathology.
201 s compacta and accumulation of intraneuronal cytoplasmic inclusions rich in alpha-synuclein called 'L
202 f Mallory bodies (MBs), which are hepatocyte cytoplasmic inclusions seen in several liver diseases.
203 S VAPB protein and ubiquitinated proteins in cytoplasmic inclusions, selectively in motor neurons.
205 ha, which promotes the formation of discrete cytoplasmic inclusions, termed stress granules (SGs).
206 infected cell morphology, including a large cytoplasmic inclusion that corresponds to the virion ass
207 component of Lewy bodies, the proteinaceous cytoplasmic inclusions that are the pathological hallmar
208 ecting the lateral white matter and neuronal cytoplasmic inclusions that bind anti-superoxide dismuta
209 iated monomers, are cytotoxic and form round cytoplasmic inclusions that can be prevented by inhibiti
210 n rotenone-treated rats accumulate fibrillar cytoplasmic inclusions that contain ubiquitin and alpha-
212 nd is accompanied by the evolution of SGs to cytoplasmic inclusions that recapitulate the pathology o
214 e demonstrate that lanthanides are stored as cytoplasmic inclusions that resemble polyphosphate granu
215 resent in normal numbers and contained large cytoplasmic inclusions that were confirmed immunohistoch
216 shold, mutant N-htt was rapidly recruited to cytoplasmic inclusions that were initially devoid of Ub.
217 without necessarily becoming constituents of cytoplasmic inclusions themselves remains relatively une
218 in a highly selective manner, before forming cytoplasmic inclusions through a concentration-dependent
219 replication intermediates and accumulates in cytoplasmic inclusions (viroplasms), sites of genome RNA
221 cells than in BS-C-1 or HeLa cells, in which cytoplasmic inclusions were decorated with scaffold prot
222 Although no differences in neuronal or glial cytoplasmic inclusions were identified between the group
223 en in hTDP-43-DeltaNLS mice, suggesting that cytoplasmic inclusions were not required to induce neuro
224 Cortical fused in sarcoma-positive neuronal cytoplasmic inclusions were often 'Pick body-like' in ne
225 (defined as type 1); those containing glial cytoplasmic inclusions were synSAA-positive and produced
226 ere synSAA-positive type 1; those with glial cytoplasmic inclusions were synSAA-positive type 2; and
229 is phenotype and suppressed the formation of cytoplasmic inclusions, whereas reduction of endogenous
230 anatomically by the distribution of neuronal cytoplasmic inclusions, whereas the tufted astrocytes di
231 virus replication cycle resides within viral cytoplasmic inclusions, which are biosynthetic centers o
232 rotein to form filaments that aggregate into cytoplasmic inclusions, which contribute to the dysfunct
233 Only mutant huntingtin formed nuclear and cytoplasmic inclusions, which increased with polyglutami
234 DPRs, poly(GA) is highly susceptible to form cytoplasmic inclusions, which is a characteristic of C9F
236 ding protein of 43 kDa) and ubiquilin 2 into cytoplasmic inclusions within LMNs, features characteris
237 and raccoonpox viruses, form large, discrete cytoplasmic inclusions within which mature virions (MVs)