ライフサイエンスコーパス: cytosolic calcium

1 ular calcium and is accompanied by increased cytosolic calcium.

2 increases in mitochondrial-derived H2O2 and cytosolic calcium.

3 ch can be substantially rescued by restoring cytosolic calcium.

4 viours in response to transient increases in cytosolic calcium.

5 boxyl termini, as detected by changes in the cytosolic calcium.

6 ons relies on antigen-dependent increases in cytosolic calcium.

7 in the context of HBV replication, elevates cytosolic calcium.

8 espite inducing a significant rise in global cytosolic calcium.

9 e proposed HBx function is the regulation of cytosolic calcium.

10 flow shear stress with the typical change in cytosolic calcium.

11 lead to cell depolarization and increases in cytosolic calcium.

12 (FGP phage), elicits a transient increase in cytosolic calcium.

13 osphorylation in response to oscillations in cytosolic calcium.

14 actomyosin contractility through increasing cytosolic calcium.

15 sm as thapsigargin (TG), involving increased cytosolic calcium.

16 riched for genes related to the elevation of cytosolic calcium.

17 ir depends on the injury-induced increase in cytosolic calcium.

18 y to stress responses involving elevation of cytosolic calcium.

19 triggers an increase in the concentration of cytosolic calcium(8-10).

20 ms, it is unknown what initiates the rise of cytosolic calcium across the wound field.

21 This increase in cytosolic calcium activated by postsynaptic Gs-coupled C

22 In the absence of nuclear calcium signaling, cytosolic calcium activating nuclear factor of activated

23 is is typically triggered by an elevation in cytosolic calcium activity.

24 s both regulate liver function by increasing cytosolic calcium, although how these calcium signals ar

25 olipase C pathway, leading to an increase in cytosolic calcium and activation of PKC.

26 hich together induce death through a rise in cytosolic calcium and activation of toll-like receptor-4

27 frequency spiking, irreversible increases in cytosolic calcium and cell death.

28 responsible for the slower sequestration of cytosolic calcium and consequent prolonged muscle relaxa

29 optical system to measure action potential, cytosolic calcium and contraction simultaneously using f

30 de receptor2/lipoxin A4 receptor, suppresses cytosolic calcium and decreases activation of the calciu

31 ls, such as glycolysis inhibition, increased cytosolic calcium and endoplasmic reticulum stress.

32 FLARE senses the coincidence of elevated cytosolic calcium and externally applied blue light, whi

33 ation of S-type anion currents downstream of cytosolic calcium and extracellular calcium-induced stom

34 g the notion that ERA1 functions upstream of cytosolic calcium and indicating the genetic interaction

35 tic load placed on neurons by increased free cytosolic calcium and may help explain the neuroprotecti

36 Both the VEGF165-mediated rise in cytosolic calcium and membrane depolarization are elimin

37 Cytosolic calcium and membrane potential were monitored

38 Cytosolic calcium and nitric oxide recordings further sh

39 Beyond transient elevation of cytosolic calcium and perturbation of Na+/K+ homeostasis

40 loading them with Fluo-4/Fura Red to measure cytosolic calcium and positioning them in direct contact

41 studies showing simultaneous measurement of cytosolic calcium and protein kinase A activity are show

42 cancer cells by 2 mechanisms: attenuation of cytosolic calcium and stabilization of lysosomes.

43 and promote increased SOCE to sustain higher cytosolic calcium and stimulate HBV replication.

44 ations (0.1 microM), increases of guard cell cytosolic calcium and stomatal closure were activated to

45 tinely contribute to the regulation of basal cytosolic calcium and that their relative role correlate

46 the effects of activators and inhibitors of cytosolic calcium and tyrosine kinase signaling pathways

47 ed increases in tyrosine phosphorylation and cytosolic calcium, and are likely to contribute to TCR-p

48 urse measurements of inositol trisphosphate, cytosolic calcium, and diacylglycerol, focuses particula

49 olipase C activation, transient increases in cytosolic calcium, and downstream activation of phosphoi

50 2-induced increases in oxidative metabolism, cytosolic calcium, and ductal smooth muscle cells prolif

51 ilization (LMP), a sustained accumulation of cytosolic calcium, and eventually cell death in pancreat

52 preserved mitochondrial morphology, reduced cytosolic calcium, and prevented cell death.

53 SP rapidly increases cytosolic calcium, and so does IL-33 to a smaller extent

54 nt oscillations in the concentration of free cytosolic calcium are a vital mechanism for the control

55 nt oscillations in the concentration of free cytosolic calcium are a vital mechanism for the control

56 Changes in cytosolic calcium are crucial for numerous processes inc

57 2 family members and subsequent elevation of cytosolic calcium are important for HBV viral replicatio

58 rent evidence suggests an important role for cytosolic calcium as a second messenger.

59 m, and AAL(R) treatment resulted in elevated cytosolic calcium, Bax redistribution from cytosol to mi

60 4) and its heterodimeric partner, MRP-8, are cytosolic calcium-binding proteins, highly expressed in

61 n reports the neuronal distribution of three cytosolic calcium-binding proteins: calbindin-D28k (CB),

62 Studies indicate that an increase in cytosolic calcium boosts the generation of H(2)O(2).

63 y response, driven most significantly by the cytosolic calcium buffering system and changes in diasto

64 y the activation of the cAMP-sensor Epac1 or cytosolic calcium but are unaffected by protein kinase C

65 This study investigates the regulation of cytosolic calcium by corticotropin-releasing factor (CRF

66 annel activity by sensitizing the channel to cytosolic calcium (Ca(2)+).

67 ) and disrupt membrane integrity, leading to cytosolic calcium (Ca(2+)) elevation.

68 Cytosolic calcium (Ca(2+)) is a ubiquitous second messen

69 ng concentrations found in patients, induced cytosolic calcium (Ca(2+)) oscillations in a human neuro

70 ,4,5)-trisphosphate receptors (InsP(3)R1) by cytosolic calcium (Ca(2+)) plays an essential role in th

71 r stimulation evokes increases in astrocytic cytosolic calcium (Ca(2+)) within the barrel cortex of a

72 Furthermore, tip cytosolic calcium ([Ca(2)(+)](cyt) ) oscillations were d

73 cerk1 plants had an irregular increase of cytosolic calcium ([Ca(2+) ]cyt ) after NaCl treatment.

74 athways including phosphoinositide-dependent cytosolic calcium ([Ca(2+) ]i ) increases, which can adv

75 f the pathophysiology of KATPHI, we examined cytosolic calcium ([Ca(2+)] i ), insulin secretion, oxyg

76 With the increase of caffeine dose (0-50 mM) cytosolic calcium ([Ca(2+)](c)) increased from 85+/-15 n

77 ecystokinin (CCK) results in an elevation of cytosolic calcium ([Ca(2+)](c)) through activation of in

78 uced elevations in the concentration of free cytosolic calcium ([Ca(2+)](cyt)) and stomatal closure i

79 ritic mitochondrial network, and couple with cytosolic calcium ([Ca(2+)](cyto)) transients in a proba

80 as well as the hypoxia-induced increases in cytosolic calcium ([Ca(2+)](i)), assessed by the Ca(2+)-

81 AM was used to measure the concentrations of cytosolic calcium ([Ca(2+)]c).

82 ysregulates calcium homeostasis by elevating cytosolic calcium ([Ca(2+)]cyt) and decreasing endoplasm

83 ncer-like phenotype is promoted by increased cytosolic calcium ([Ca(2+)]cyto), aerobic glycolysis, an

84 ndria act as significant, dynamic buffers of cytosolic calcium ([Ca(2+)]i) in heart.

85 zation, voltage gated K(+) channel activity, cytosolic calcium [Ca(2+) ](cyt) and reactive oxygen spe

86 Mechanisms that control mobilization of cytosolic calcium [Ca(2+)](i) are key for regulation of

87 itochondrial axonal transport in response to cytosolic calcium (Ca2+) levels ([Ca2+]c) and mitochondr

88 pressure changes in the pancreas can elevate cytosolic calcium (Ca2+) levels, it is not known how tra

89 In vitro changes in cytosolic calcium ([Ca2+]c) and chemosensory discharge w

90 tical during fertilization and triggers free cytosolic calcium ([Ca2+]cyto) as a key signal for egg a

91 erlying such insensitivity to transitions in cytosolic calcium ([Ca2+]i) in microvascular endothelial

92 Cytosolic calcium ([Ca2+]i) responses to MIP-2/PAF were

93 Acute transitions in cytosolic calcium ([Ca2+]i) through store-operated calci

94 er calcium increases, we measured changes in cytosolic calcium ([Ca2+]i) using fura 2-AM (fluorescenc

95 zation, voltage gated K(+) channel activity, cytosolic calcium [Ca2+]cyt and reactive oxygen species

96 gonist anti-Tim-1 mAb elicits a rise in free cytosolic calcium, calcineurin-dependent nuclear translo

97 asmic reticulum stress in a manner requiring cytosolic calcium, calcium/calmodulin-dependent protein

98 The increase in cytosolic calcium caused by activation of Gq-coupled AT1

99 AMPK was induced by elevated cytosolic calcium caused by impaired sarco/endoplasmic r

100 Interestingly, the cytosolic calcium chelator BAPTA-AM and K-201 protected

101 Cytosolic calcium concentration ([Ca(2+) ](cyt) ) and he

102 the effect of 4-aminopyridine (4-AP) on free cytosolic calcium concentration ([Ca(2+)](i)) in basal c

103 The consequent lowering of the cytosolic calcium concentration ([Ca(2+)](i)), if protra

104 Oscillations in cytosolic calcium concentration ([Ca2+]cyt) are central

105 y treated with nitrite had a lower force and cytosolic calcium concentration during single non-fatigu

106 reveals that: calcium signals in the form of cytosolic calcium concentration elevations are nonlinear

107 macological agents as measured by changes in cytosolic calcium concentration for the rapid classifica

108 lin-1 produces a dose-dependent elevation in cytosolic calcium concentration in ET(B)-transfected cel

109 Here we show that a chronic increase of the cytosolic calcium concentration in hepatocytes during ob

110 exin II, V, or VI inhibited the increases in cytosolic calcium concentration in RA-treated chondrocyt

111 Robust elevation of the cytosolic calcium concentration is a crucial early step

112 A dramatic rise in free cytosolic calcium concentration is thought to be a centr

113 The resulting increased cytosolic calcium concentration leads to a further up-re

114 Glucagon increased cytosolic calcium concentration through the PKA-mediated

115 peed measurements of cell length changes and cytosolic calcium concentration using confocal line scan

116 h RA and EDTA revealed that increases in the cytosolic calcium concentration were due to influx of ex

117 the mitochondria and an increase in the free cytosolic calcium concentration were observed.

118 nucleus correlate with transient changes in cytosolic calcium concentration within these progenitor

119 s not appear to be in response to changes in cytosolic calcium concentration, [Ca(2+)](i).

120 ineralization of these cultures: increase in cytosolic calcium concentration, followed by up-regulati

121 oforms respond to the signal of an increased cytosolic calcium concentration.

122 hways and displaying an acute effect on free cytosolic calcium concentration.

123 Measurement of cytosolic calcium concentrations ([Ca(2+)](i)) in tubule

124 healis cells were loaded with fura 2-AM, and cytosolic calcium concentrations ([Ca2+]i) were measured

125 The calculated cytosolic calcium concentrations are 368 +/- 68 nM and 6

126 Cytosolic calcium concentrations were assessed under the

127 n transmembrane potential and an increase in cytosolic calcium concentrations, are inhibited by low l

128 vated currents, or NMDA-induced increases in cytosolic calcium concentrations.

129 ased calcium permeability and elevated basal cytosolic calcium concentrations.

130 ondrial biogenesis in response to increasing cytosolic calcium concentrations.

131 membrane inward K+ conductance (IK,in) in a cytosolic calcium-dependent manner.

132 ion of inositol trisphosphate production and cytosolic calcium distribution, substrates for many acut

133 The TMEM173-dependent increase in cytosolic calcium drives Gasdermin D (GSDMD) cleavage an

134 ry complex is not disrupted by elevations of cytosolic calcium during cardiac contraction (systole).

135 RCA2a), the pump responsible for reuptake of cytosolic calcium during diastole, plays a central role

136 Using the kinetic model for cytosolic calcium dynamics in RAW 264.7 cells developed

137 quantification of the contractile forces and cytosolic calcium dynamics of muscle fibers embedded in

138 method for measuring contractile forces and cytosolic calcium dynamics of single muscle fibers.

139 ent HBx binding to Bcl-2 and Bcl-xL abrogate cytosolic calcium elevation and cell death induced by HB

140 sponsive genes and diminished chitin-induced cytosolic calcium elevation as well as enhanced suscepti

141 oteins through its BH3-like motif to promote cytosolic calcium elevation, cell death, and viral repli

142 phorylated, resulting in ER calcium leak and cytosolic calcium elevation.

143 lation of SERCA, resulting in an increase in cytosolic calcium, enhanced NF-kappaB activity, and upre

144 ential canonical (TRPCs) channels to control cytosolic calcium equilibria and consequent cell behavio

145 ion of the signalling network underlying the cytosolic calcium fluctuations are hitherto not fully un

146 ysregulated integrin alphaIIbbeta3-dependent cytosolic calcium flux and phosphatidylinositol(3,4)P2 a

147 atory reserve, independent of alterations in cytosolic calcium flux.

148 this activation may occur in the absence of cytosolic calcium fluxes.

149 of VEGF165 to cells elicits a rapid rise in cytosolic calcium followed by a slower decline toward co

150 kely in response to an observed elevation in cytosolic calcium following diazoxide treatment.

151 le effect on OCR despite a large increase in cytosolic calcium, further supporting the notion that in

152 asmic reticulum calcium pumps, but buffering cytosolic calcium had no effect.

153 Raising cytosolic calcium has been shown to activate calcium/cal

154 rice and barley aleurone because changes in cytosolic calcium have been implicated in the response o

155 As a pharmacological approach to restore cytosolic calcium homeostasis in vivo, we administered t

156 d with Fluo-4/AM revealed that ATP mobilized cytosolic calcium in astrocytic end feet, whereas electr

157 d PAR1-AP (10 microM) induced an increase in cytosolic calcium in both anterior and equatorial lens c

158 n (from -51+/-2 to -44+/-1 mV) and increased cytosolic calcium in both rat and human PASMCs.

159 Enhanced cytosolic calcium in CBE-N2a cells was blocked by either

160 te store-operated calcium entry and increase cytosolic calcium in endothelium.

161 Second, NAADP increased cytosolic calcium in isolated cells when microinjected a

162 d induce a pertussis toxin-sensitive rise in cytosolic calcium in monocytes as well as in neutrophils

163 Previous studies have shown that raising cytosolic calcium in myotubes induces increases in perox

164 DREADD activation increased cytosolic calcium in primary astrocytes, facilitated res

165 on exists between intracellular H(2)O(2) and cytosolic calcium in response to biotic and abiotic stre

166 This finding suggests that the increases in cytosolic calcium in skeletal muscle during exercise may

167 Measurements of cytosolic calcium in spontaneously beating cells showed

168 orting the positioning of era1-2 upstream of cytosolic calcium in the guard cell ABA signaling cascad

169 neuropeptide FF, evoked a rapid increase in cytosolic calcium in the MrgC11 expressing cells but not

170 a substance(s) that stimulated increases in cytosolic calcium in the MrgC11 expressing cells that fa

171 e, enabling determination of the dynamics of cytosolic calcium in the perfused mouse heart.

172 P3-mediated calcium release and elevation of cytosolic calcium in WEHI7.2 T cells.

173 The increased cytosolic calcium, in turn, led to the phosphorylation o

174 re a higher level of shear stress to evoke a cytosolic calcium increase than do mouse renal epithelia

175 Additionally, muscle cytosolic calcium increased in the Antimycin A-treated w

176 Cytosolic calcium increased with incubation time in both

177 type in wild-type plants both in ABA-induced cytosolic calcium increases and in seed germination, and

178 n of seed germination, stomatal closing, and cytosolic calcium increases in guard cells.

179 es show a reduced sensitivity of ABA-induced cytosolic calcium increases in rcn1, whereas mechanisms

180 es in rcn1, whereas mechanisms downstream of cytosolic calcium increases show wild-type responses, su

181 ithin the mitochondrial matrix regulates the cytosolic calcium increases that drive GSIS remains a my

182 Cytosolic calcium increases were analyzed in guard cells

183 ceptor-dependent manner, Rac1 activation and cytosolic calcium increases.

184 Evidence that group VIA cytosolic calcium-independent phospholipase A(2) (iPLA(2

185 f three recombinant human enzymes, including cytosolic, calcium-independent, and secreted phospholipa

186 o discriminate between the varying levels of cytosolic calcium induced by different stimuli.

187 Cytosolic calcium influx activates signaling pathways kn

188 hat compound A analogs decreased GLT-induced cytosolic calcium influx in islet cells, and all measure

189 arious signaling pathways rely on changes in cytosolic calcium ion concentration ([Ca2+]i).

190 A surge in cytosolic calcium ion concentration by entry of extracel

191 e receptor 5 (mGluR5)-dependent increases in cytosolic calcium ions (Ca(2+)) in response to glutamate

192 These data suggest that elevated cytosolic calcium is a common critical process for all r

193 fission is disabled, AC-induced increase in cytosolic calcium is blunted owing to mitochondrial calc

194 Cytosolic calcium is involved in the regulation of many

195 the notion that influx of calcium, not bulk cytosolic calcium, is associated with the increase in AT

196 manifested as intercellular waves of rising cytosolic calcium, is, in many cell types, the result of

197 in a signaling pathway by which increases in cytosolic calcium lead to increases in peroxisome prolif

198 evis egg extract, we found that increases in cytosolic calcium lead to the activation of an endogenou

199 ontaneous calcium elevations as a measure of cytosolic calcium leak.

200 However, an increase in cytosolic calcium led to exocytosis of only the lysosome

201 unted in Ussing chambers for measurements of cytosolic calcium levels ([Ca(2+)](i)), membrane voltage

202 ular signaling pathway resulting in elevated cytosolic calcium levels ([Ca(2+)](i)).

203 GTPase-1 (Miro1) which acts as a sensor for cytosolic calcium levels ([Ca(2+)]c); elevated [Ca(2+)]c

204 It is now evident that elevation of cytosolic calcium levels ([Ca2+]i) can compromise the BB

205 inc finger 1 (IKZF1), resulting in increased cytosolic calcium levels and activation of a calcium-dep

206 ) inhibited isoflurane-induced elevations in cytosolic calcium levels and attenuated isoflurane-induc

207 TG neurons showed decreased basal cytosolic calcium levels and decreased Ca(2+) cytosolic

208 hibit impaired rate-dependent enhancement of cytosolic calcium levels and fractional shortening.

209 Resveratrol increased cytosolic calcium levels and promoted AMPK activation by

210 required for the Wnt-5a-mediated increase in cytosolic calcium levels and spinogenesis.

211 atment of cells with compounds that increase cytosolic calcium levels by a variety of mechanisms resc

212 brane calcium-ATPase (PMCA) helps to control cytosolic calcium levels by pumping out excess Ca2+.

213 Real time measurements of cytosolic calcium levels during heating in Arabidopsis d

214 umin, suggesting that transient increases in cytosolic calcium levels function to mobilize intracellu

215 o induce EMT produce a transient increase in cytosolic calcium levels in human breast cancer cells.

216 Expression of wolframin also increased cytosolic calcium levels in oocytes.

217 ular calcium, in a manner that followed peak cytosolic calcium levels in the aggregate.

218 anisms in taste cells that functions to keep cytosolic calcium levels in the appropriate range for ce

219 -adaptor that translates a transient rise in cytosolic calcium levels into more persistent SEC31 ubiq

220 ectly suppresses the electrical activity and cytosolic calcium levels of orexin cells.

221 Studies in many organisms have shown that cytosolic calcium levels rise within a field of cells ar

222 discharge (AD) causes prolonged elevation in cytosolic calcium levels that is associated with prolong

223 s are more toxic to neurons due to increased cytosolic calcium levels throughout their action on NMDA

224 ly41 to the early secretory pathway elevates cytosolic calcium levels to suppress vesicle-tethering m

225 hich may contribute to observed increases in cytosolic calcium levels under conditions of oxidative s

226 and when stimulated by amino acids, whereas cytosolic calcium levels were not affected.

227 of RVB and RVC NSP4s significantly elevated cytosolic calcium levels, demonstrating that despite str

228 reticulum (ER) stores as manifested by lower cytosolic calcium levels, higher expression of the ER pr

229 se activation and apoptosis are dependent on cytosolic calcium levels, should facilitate the provisio

230 ich include periodic, transient increases in cytosolic calcium levels, termed calcium spiking.

231 e influx channel and consequently increasing cytosolic calcium levels.

232 ream signalling pathways including increased cytosolic calcium levels.

233 Sly41 overexpression significantly increases cytosolic calcium levels.

234 EA also caused a sustained increase in cytosolic calcium levels.

235 IM-3/Gal-9 signaling involving modulation of cytosolic calcium levels.

236 also triggered integrin-dependent changes in cytosolic calcium, measured by single cell imaging.

237 Triple combined recordings of cytosolic calcium, mitochondrial calcium and NADH reveal

238 ations to FAEEs induced a larger increase in cytosolic calcium, mitochondrial depolarization, and nec

239 n species through a mechanism dependent upon cytosolic-calcium mobilization and a significant decline

240 eukemia cells (U937) manifested by immediate cytosolic-calcium mobilization, GADD153 and GADD34 prote

241 teoblasts failed to elicit the increments in cytosolic calcium observed in wild-type controls.

242 individual measurement of action potential, cytosolic calcium or contraction.

243 rimarily probe cell-based variables, such as cytosolic calcium or membrane potential, but not cell-to

244 support without arrhythmogenic increases in cytosolic calcium or side effects of more traditional ag

245 The role of cytosolic calcium oscillation has long been recognized i

246 ons of vasopressin only will evoke localized cytosolic calcium oscillations and modest increases in h

247 ng studies revealed that PHE caused dramatic cytosolic calcium oscillations in NST neurones.

248 ticulum in zebrafish ECs and is required for cytosolic calcium oscillations in response to Vegfa.

249 During the transient cytosolic calcium oscillations induced by intermediate d

250 These oscillations may be in phase with cytosolic calcium oscillations or out of phase.

251 Our results suggest that taming cytosolic calcium overload in pancreatic islets can impr

252 especially those related to the elevation of cytosolic calcium (P = 2 x 10-4).

253 arathyroid and other cell types, and include cytosolic calcium, phospholipases C, A2, and D, protein

254 The elevation in cytosolic calcium potentiated calcium-sensitive potassiu

255 m of its fatty acid, lowered the increase in cytosolic calcium, prevented the loss of mitochondrial m

256 ntracellular signaling via second messengers-cytosolic calcium, reactive oxygen species, and nitric o

257 ocytes, suggesting a diminished capacity for cytosolic calcium removal not associated with a change i

258 The calcium chelator BAPTA-AM, which reduces cytosolic calcium, rescues the defective ATP2C1 KO pheno

259 ange while the EC50s for phospho-Erk and the cytosolic calcium response did shift 100-fold.

260 ors are mainly activated by ATP, mediating a cytosolic calcium response.

261 ility of IL-3 to alter secretagogue-mediated cytosolic calcium responses following 18-h cultures, 18-

262 In the present study raising cytosolic calcium resulted in increases in phosphorylati

263 stress-induced apoptosis, we have shown that cytosolic calcium resulting from ER stress induces expre

264 yocytes had delayed sarcomere relaxation and cytosolic calcium reuptake kinetics, indicating diastoli

265 Measurement of cytosolic calcium showed normal basal levels and abnorma

266 Experimental increases of cytosolic calcium showed that the activation of S-type a

267 This results in inhibition of cytosolic calcium signaling and down-regulation of HGF-i

268 nked HBx regulation of cell proliferation to cytosolic calcium signaling and HBx stimulation of HBV r

269 cyclosporine H, and SDZ NIM811, which block cytosolic calcium signaling and specifically the mitocho

270 nt, amplitude of field action potential, and cytosolic calcium signaling of cardiomyocytes.

271 Parotid acinar cells exhibit rapid cytosolic calcium signals ([Ca2+]i) that initiate in the

272 l cells (ECs), we discovered that repetitive cytosolic calcium signals (oscillations) chronically loa

273 otential, sequestration of hormonally evoked cytosolic calcium signals and timing of permeability tra

274 Exactly how HBx elevates cytosolic calcium signals is not clear.

275 Cytosolic calcium signals were studied using Fura Red or

276 lcium (CRAC) channel and generates sustained cytosolic calcium signals when triggered by depletion of

277 One fundamental HBx function is elevation of cytosolic calcium signals; this HBx activity has been li

278 or, we show that XA triggers a rapid rise in cytosolic calcium specifically in gametocytes that is es

279 LEC-2-induced platelet activation results in cytosolic calcium spiking, which was confirmed by single

280 channel activation, leading to increases in cytosolic calcium that activate the AMPK upstream kinase

281 nly, sigma antagonists evoke a rapid rise in cytosolic calcium that is inhibited by sigma-1 agonists.

282 K(ATP) conductance is increased by rises in cytosolic calcium through indirect effects on metabolism

283 with a concentration of caffeine that raises cytosolic calcium to a concentration too low to cause co

284 We linked this elevation of cytosolic calcium to the association of HBx with the mit

285 raction, action potential (AP) morphology or cytosolic calcium transient (CaT) amplitude--is a high r

286 nd attenuates the metabolic coupling between cytosolic calcium transients and activation of matrix de

287 ology by stimulating ATP production, shaping cytosolic calcium transients and regulating cell death.

288 This led to abnormally high cytosolic calcium transients in presynaptic terminals an

289 rs of Wnt5a-mediated actomyosin polarity and cytosolic calcium transients that orient and drive mesen

290 RII constructs showed significant effects on cytosolic calcium transients.

291 nction plays an essential role in activating cytosolic calcium transitions through the membrane I(SOC

292 In DLS, minimal increases in cytosolic calcium trigger steep DA release while PreCaTs

293 Since elevation of cytosolic calcium triggered by avirulent P. syringae was

294 The sequential rise and fall of cytosolic calcium underlies the contraction-relaxation c

295 opment of individual signals: an increase in cytosolic calcium was accompanied by a slower mitochondr

296 Recovery of cytosolic calcium was faster than recovery of mitochondr

297 play a major role in the rapid buffering of cytosolic calcium, we hypothesized that altered mitochon

298 GluR1alpha maintains its ability to increase cytosolic calcium while it no longer activates the neuro

299 high-affinity rhodamine-dextran or chelating cytosolic calcium with BAPTA-AM attenuated Tat endolysos

300 or therapeutic intervention, as elevation of cytosolic calcium with curcumin normalized NPC1 disease