ライフサイエンスコーパス: cytotoxic activity

1 ls of proinflammatory cytokine secretion and cytotoxic activity.

2 rain JGS1076 CPB variant that possessed more cytotoxic activity.

3 Ls and NK cells diminishes degranulation and cytotoxic activity.

4 ivation and DNMT1 expression correlated with cytotoxic activity.

5 says the compounds displayed anti-fungal and cytotoxic activity.

6 essing cancer cells, displaying MET-specific cytotoxic activity.

7 It has been shown that it holds a high cytotoxic activity.

8 high antioxidant activity with an ignorable cytotoxic activity.

9 th TNF-alpha and IFN-gamma and showed potent cytotoxic activity.

10 NK) cells are innate lymphocytes with potent cytotoxic activity.

11 control CD19(+) B cells and increased their cytotoxic activity.

12 ) T cells after Ag presentation and impaired cytotoxic activity.

13 LM for DNA cleavage, cancer cell uptake, and cytotoxic activity.

14 pacity to driving T cell differentiation and cytotoxic activity.

15 he ability to produce effector cytokines and cytotoxic activity.

16 t fully with differences in the intensity of cytotoxic activity.

17 ted tumor growth by inhibiting CD8(+) T cell cytotoxic activity.

18 ortant role of mitochondria in mediating the cytotoxic activity.

19 or is an ATP-gated ion channel known for its cytotoxic activity.

20 esponses, but may also acquire TLR-triggered cytotoxic activity.

21 /CA/07/2009) peptides and showed evidence of cytotoxic activity.

22 ed peptide-specific IFN-gamma production and cytotoxic activity.

23 and MyD88(-/-) mice showed markedly impaired cytotoxic activity.

24 manner that was correlated tightly with its cytotoxic activity.

25 f POPC/POPS liposomes for peptides with high cytotoxic activity.

26 sed on tumor cells that can activate NK cell cytotoxic activity.

27 utation restored both hemolytic activity and cytotoxic activity.

28 ATM-p53 apoptosis pathway that underlies its cytotoxic activity.

29 gondii cysts through their perforin-mediated cytotoxic activity.

30 ractions that can cause an increase in their cytotoxic activity.

31 e natural product that possesses significant cytotoxic activity.

32 e impairment of their antigen specificity or cytotoxic activity.

33 reased cytokine polyfunctionality but lacked cytotoxic activity.

34 and they mediate influenza A virus-specific cytotoxic activity.

35 in the presence of HLA-A2, without eliciting cytotoxic activity.

36 that affect their biochemical behaviour and cytotoxic activity.

37 results in a significant reduction of their cytotoxic activity.

38 macological GSK3 inactivation enhances their cytotoxic activity.

39 ients (AML-NK) show a dramatic impairment in cytotoxic activity.

40 ells, where the drug is released and induces cytotoxic activity.

41 ven by chronic TCR stimulation while sparing cytotoxic activity.

42 tracts and their in vitro anti-proliferative/cytotoxic activities.

43 iterpenes with significant antimicrobial and cytotoxic activities.

44 ial source of compounds with antioxidant and cytotoxic activities.

45 Two nucleoside derivatives with promising cytotoxic activities (11 and 12) were further analyzed o

46 gnificant enhancement in cellular uptake and cytotoxic activity after 1h of heating at 42 degrees C w

47 derivatives were prepared and optimized for cytotoxic activities against FLT3-ITD mutant cancer cell

48 s as well as effective antiproliferative and cytotoxic activities against human tumor cells.

49 NT-7-16 exhibits antiproliferative and cytotoxic activities against multiple cancer cell lines,

50 ed that human eosinophils and T cells shared cytotoxic activities against tumor cells that involved t

51 nanomolar concentration and showed in vitro cytotoxic activity against a panel of human tumor cell l

52 erivative, 3 [Ga(ACtpfc)], demonstrated high cytotoxic activity against all NCI60 cell lines derived

53 TILN NK cells display robust cytotoxic activity against autologous melanoma cells.

54 NKp46+ CD3+ cells exhibit cytotoxic activity against autologous Theileria parva-in

55 xic against malignant B-cell lines, has high cytotoxic activity against cells directly isolated from

56 ers, including CD56+ and perforin, and exert cytotoxic activity against different human tumor target

57 increased binding affinity to and increased cytotoxic activity against Fas(+) target cells.

58 5, 8, 9, 11, and 13 were evaluated for their cytotoxic activity against four cancer cell lines (SK-ME

59 Antibody-dependent cell-mediated cytotoxic activity against FRalpha is also associated wi

60 inhibitor G5 were synthesized and tested for cytotoxic activity against glioblastoma cells.

61 Two R. sempervirens extracts exerted cytotoxic activity against HeLa and HT-29 cell lines, bu

62 c effects, punicatannin C induced a moderate cytotoxic activity against HepG2 and MCF-7 cell lines.

63 excellent pharmacokinetics, potent in vitro cytotoxic activity against Her2(+) cancer cells, and com

64 es have been investigated for their in vitro cytotoxic activity against Jurkat, K562, U937, and HL60

65 diol and clauslactone E showed a significant cytotoxic activity against Leishmania major with IC50 va

66 IL) is a death ligand cytokine known for its cytotoxic activity against malignantly transformed cells

67 prepared 2H-chromenes demonstrated profound cytotoxic activity against MCF-7 cell line.

68 lls exhibit improved expansion and increased cytotoxic activity against multiple tumor cell lines whe

69 eration arrest and apoptosis without causing cytotoxic activity against normal human CD34(+) progenit

70 show that human neutrophils display a higher cytotoxic activity against poorly metastatic cells compa

71 Seventeen new macrocycles were evaluated for cytotoxic activity against RPMI 8402, KB-3, and KB-3 cel

72 nolactone-2',3'-diol possessed the strongest cytotoxic activity against SBC3, A549, K562, and K562/AD

73 uct to target alpha-tubulin, displays potent cytotoxic activity against sensitive and resistant A2780

74 These nanovesicles display cytotoxic activity against several tumor cell lines and

75 p70 to form a stable Tag7-Hsp70 complex with cytotoxic activity against some tumor cell lines.

76 Natural killer (NK) cells display cytotoxic activity against susceptible target cells and

77 activated macrophages exhibited NK cell-like cytotoxic activity against target cells in a perforin/gr

78 or allogeneic sources, thereby promoting NK cytotoxic activity against target cells that would not b

79 r endothelial cells in vitro, they only show cytotoxic activity against the tumor endothelial cells.

80 ator of the cytotoxic effect, as the reduced cytotoxic activity against the yeast cells detected in p

81 A-D expression, cancerous pDCs did not exert cytotoxic activity against tumor cells but instead promo

82 Natural killer (NK) cells not only exert cytotoxic activity against tumor cells or infected cells

83 NVS-CECR2-1 exhibits cytotoxic activity against various human cancer cells, k

84 , that exhibits potent antiproliferative and cytotoxic activity along with client protein degradation

85 Unlike in WT, in vivo cytotoxic activity analysis of alloreactive Tmem recall

86 Tc17/IFN-gamma) subsets that exhibit strong cytotoxic activities and are associated with pathogenesi

87 The antibody Fc region regulates antibody cytotoxic activities and serum half-life.

88 s model drugs, as these agents have a potent cytotoxic activity and are easy to synthesize.

89 ng to proteolysis products also promoted the cytotoxic activity and binding of enterotoxin and beta t

90 f TGF-beta1 was sufficient to augment T cell cytotoxic activity and blocked tumor growth and metastas

91 in a series of cell-culture assays to assess cytotoxic activity and cell binding.

92 , we investigated the mechanisms controlling cytotoxic activity and cytokine production in response t

93 gnaling pathways responsible for controlling cytotoxic activity and cytokine production.

94 ns offer unique advantages such as increased cytotoxic activity and diminished antibody recognition,

95 in designed to have low-immunogenicity, high-cytotoxic activity and fewer side effects.

96 e, which correlated with increased pulmonary cytotoxic activity and increased pulmonary expression of

97 C. jejuni OMVs possess cytotoxic activity and induce a host immune response fro

98 Cytotoxic activity and interferon-gamma (IFN-gamma) secr

99 from mice pretreated with alphaGalCer retain cytotoxic activity and maintain the ability to respond t

100 primarily through stimulation of CD8+ T-cell cytotoxic activity and mitochondrial metabolism.

101 including stimulation of natural killer cell cytotoxic activity and repression of Hedgehog-dependent

102 nvestigate the correlation between immediate cytotoxic activity and short-term cytokine secretion.

103 low-affinity alphabeta-TCR maintained potent cytotoxic activity and specificity, the high-affinity TC

104 dichroism studies, a correlation between the cytotoxic activity and the alpha-helical propensity was

105 antigen presentation, chemokine expression, cytotoxic activity, and adaptive immune resistance, and

106 Y-ESO-1-specific CD8(+) T cells by enhancing cytotoxic activity, and improving viability and prolifer

107 bound CEACAM6 with high affinity, exhibited cytotoxic activity, and induced dose-dependent poly(ADP-

108 ted protein kinase (MAPK) signaling, in vivo cytotoxic activity, and intratumoral cytokine secretion

109 ts with P. aeruginosa pneumonia demonstrated cytotoxic activity, and lavage fluid contained amyloid m

110 dness, tested their culture supernatants for cytotoxic activity, and searched for secreted toxins.

111 The analogs displayed a range of cytotoxic activity, and surprisingly, the most active mi

112 The new compounds were evaluated for their cytotoxic activity, and this allowed the identification

113 Surprisingly, CD4(+) T cells developed cytotoxic activity, and tumor rejection was dependent on

114 -specific cells that are granzyme B(+), have cytotoxic activity, and/ or produce interferon gamma (IF

115 Their cytotoxic activity appears to involve redox mechanisms.

116 publicly available library of compounds with cytotoxic activity ( approximately 21,000 compounds), in

117 through which pDCs acquire and elicit their cytotoxic activity are still not clear.

118 CD8 T cell epitopes were reported to induce cytotoxic activity, are derived from early expressed gen

119 ty to secrete IFN-gamma but maintaining some cytotoxic activity as granzyme B and FasL are overexpres

120 sponge Ecionemia acervus that shows in vitro cytotoxic activities at submicromolar concentrations.

121 hereas the presence of an Fc domain enhanced cytotoxic activity, but triggered antigen-independent T-

122 However, most reports observed a lack of cytotoxic activity by Tc17 cells.

123 d 15-fold greater REV-ERBbeta inhibitory and cytotoxic activities compared to 1.

124 idation led to a decrease of antioxidant and cytotoxic activities compared to initial substrates.

125 echanistic studies reveal that the increased cytotoxic activity correlates with an increase in AML-NK

126 Cytotoxic activity could be reconstituted in both mutant

127 ion, as low affinity-primed T cells acquired cytotoxic activity earlier than high affinity-primed one

128 Notably, the compounds showed no cytotoxic activity, encouraging their further evaluation

129 ese results suggest that the degradative and cytotoxic activities exhibited by StmPr1 may contribute

130 y reports for the first time the cancer cell cytotoxic activity for NVS-CECR2-1 and provides a possib

131 nsic antibody activities and showed enhanced cytotoxic activity from targeted payload delivery.

132 activities, mutagenic/genotoxic activities, cytotoxic activities, further activities like neurotoxic

133 into the nanoparticles to confer synergistic cytotoxic activity, further highlighting the potential a

134 otential, however, FE exhibited a pronounced cytotoxic activity (GI(50) = 116 ug/mL) against HeLa cel

135 olin-6-one (16a) exhibited the best in vitro cytotoxic activity (GI50 10-66.9 nM) against the NCI 60

136 infected mice correlated with higher NK cell cytotoxic activity, higher expression of cytotoxic molec

137 lubility and stability, demonstrated extreme cytotoxic activity (IC50 < 5.0 mug/mL) to cancer cells c

138 The levels of intracellular IFN-gamma, cytotoxic activity, IFN-gamma and granzyme B secretion,

139 They display cytotoxic activities in the micromolar range on many can

140 C) levels of CD8+ T cells and enhanced their cytotoxic activity in a lymphoma coculture system.

141 s I51/A114 and at V56/F118 lacked detectable cytotoxic activity in a MDCK cell assay.

142 Arsenic sulfide (AS) has excellent cytotoxic activity in acute promyelocytic leukemia (APL)

143 from avocado fruit, as a novel compound with cytotoxic activity in AML.

144 chanism paralleling that responsible for the cytotoxic activity in cancer cells.

145 t, and HSP70 inhibitors exert tumor-specific cytotoxic activity in cancer.

146 We also found that most of the cytotoxic activity in CL lesions was triggered by NK cel

147 ANT61, which reveal the basis for its unique cytotoxic activity in colon carcinoma cells.

148 fferent dynamics of numerical alteration and cytotoxic activity in HIV-infected patients.

149 gly, this behavior correlates with efficient cytotoxic activity in human osteosarcoma and colon carci

150 ology, highlighting the important role of NK cytotoxic activity in immune homeostasis.

151 oles was synthesized and evaluated for their cytotoxic activity in in vitro tumor models.

152 whether mucosal B cells express GrB and have cytotoxic activity in inflammatory bowel disease (IBD).

153 The cytotoxic activity in nonirradiated cells of novel phtha

154 These species have little or no cytotoxic activity in several bioassays.

155 iscovery of sudemycin D6, which shows potent cytotoxic activity in the melanoma line SK-MEL-2 (IC50 =

156 units permits access to analogues possessing cytotoxic activity in the nanomolar range.

157 ificant increase in IFN-gamma production and cytotoxic activity in TILs that acquired H-RasG12V compa

158 active properties (antioxidant potential and cytotoxic activity in tumor cell lines).

159 onjugates displayed potent antigen-selective cytotoxic activity in vitro and antitumor activity in vi

160 ecognizes peptide in the context of MHC, has cytotoxic activity in vitro and prevented growth of tumo

161 cient NK cells display significantly less NK cytotoxic activity in vitro than WT NK cells.

162 e producing either one or both toxins showed cytotoxic activity in vitro that translated directly int

163 responders and nonresponders have equivalent cytotoxic activity in vitro.

164 s in human laryngeal carcinoma cells causing cytotoxic activity, in a dose dependent manner.

165 99/Venetoclax, a promising BH3-mimetic whose cytotoxic activity is counteracted by high Mcl-1/Bcl-xL

166 d temperature sensitive, suggesting that its cytotoxic activity is due to secreted proteins, some of

167 r, on the contrary to the enhancement of its cytotoxic activity, is a reaction of physiological impor

168 responding approximate 3-5-fold reduction in cytotoxic activity [L1210 IC(50) for (+)-iso-duocarmycin

169 atory potential, CD4(+) T cells also acquire cytotoxic activity marked by granzyme B (GzmB) expressio

170 The differences in the cytotoxic activities of 1 and 2 were suggested to be due

171 relative antibacterial, antiplasmodial, and cytotoxic activities of a series of proline-free and pro

172 rate a concept in which antibacterial versus cytotoxic activities of cationic small molecules are tun

173 Antioxidant and cytotoxic activities of digestates were also measured us

174 iate the immunomodulatory, inflammatory, and cytotoxic activities of human IgG antibodies and Fc engi

175 tment with ibrutinib significantly augmented cytotoxic activities of standard AML chemotherapy cytara

176 The cytotoxic activities of these compounds and their intera

177 uster, are responsible for the hemolytic and cytotoxic activities of V. anguillarum in fish.

178 ell lines is examined, observing a promising cytotoxic activity of (+)-T7 against breast carcinoma ce

179 The cytotoxic activity of 10 analogs of the idealized amphip

180 oline derivatives (8-HQs) and focuses on the cytotoxic activity of 5-Cl-7-I-8-HQ (clioquinol, CQ) cop

181 Whereas increased Ag-specific cytotoxic activity of a CD8(+) T cell line manifested in

182 We studied the cytotoxic activity of a vesicular stomatitis/measles hyb

183 Cytotoxic activity of all 43 reaction products has been

184 Finally, blockade of Rpn11 increases the cytotoxic activity of anti-MM agents lenalidomide, pomal

185 lity of this protocol was illustrated on the cytotoxic activity of azadiradione derivatives against s

186 Interestingly, I-CBP112 increased the cytotoxic activity of BET bromodomain inhibitor JQ1 as w

187 of human CMV (HCMV) infection depends on the cytotoxic activity of CD8(+) CTLs.

188 tralizing antibody production by B cells and cytotoxic activity of CD8(+) T cells are well-accepted c

189 mice, particularly regarding frequencies and cytotoxic activity of CD8(+) T cells.

190 is while decreasing PD-L1 protein to enhance cytotoxic activity of CD8(+) T cells.

191 creasing PD-L1 protein levels to enhance the cytotoxic activity of CD8(+) T cells.

192 fit has been attributed mainly to support of cytotoxic activity of CD8+ T cells.

193 functional BH3 profiling, we found that the cytotoxic activity of copanlisib was primarily mediated

194 e trastuzumab emtansine (T-DM1) combines the cytotoxic activity of DM1 with the human epidermal growt

195 Strong cytotoxic activity of DSA was associated with a higher r

196 However, cytotoxic activity of DSA was not correlated to antibody

197 tly, bispecific antibodies that redirect the cytotoxic activity of effector T cells by binding to CD3

198 PI(4,5)P2 levels was less susceptible to the cytotoxic activity of ExoU.

199 n cancer cells and provide evidence that the cytotoxic activity of HDACi in cancer is not only depend

200 p28 enhanced the cytotoxic activity of lower concentrations (IC20-50) of

201 The impairment of cytotoxic activity of lymphocytes disturbs immune survei

202 gest that acylation is not necessary for the cytotoxic activity of M. haemolytica Lkt but that it enh

203 n light of the reported selective and potent cytotoxic activity of maoecrystal V, the cytotoxic prope

204 Pretreatment with decitabine decreased the cytotoxic activity of MEK inhibitors in KRAS-mutant ovar

205 ith human blood and also in mice, mimics the cytotoxic activity of natural killer cells and increases

206 IL-27 also enhances cytotoxic activity of NK cells both in vitro and in vivo

207 At 10 nM, 33 and 44 stimulated the cytotoxic activity of NK cells.

208 thermore, regulation by HNRNPR modulates the cytotoxic activity of NK cells.

209 The cytotoxic activity of our PRAME-specific CTLs was direct

210 enhanced proliferation in vivo and enhanced cytotoxic activity of PD-1-deficient T lymphocytes again

211 CD16 expression and rituximab-dependent cell cytotoxic activity of peripheral NK cells in HT recipien

212 therapeutic strategy to markedly improve the cytotoxic activity of PI3Ki in hormonal therapy-resistan

213 NC-ADCC was not affected by C5 cleavage, the cytotoxic activity of PMN in the presence of serum stron

214 ial correlated with Fasl expression, and the cytotoxic activity of postinfection Tc17 cells was parti

215 nt with inhibitor, 7rh, greatly enhanced the cytotoxic activity of RG7787 in several cancer cell line

216 the possible use of this protein against the cytotoxic activity of ribosome-inactivating proteins.

217 -acetylcholinesterase, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree

218 content, antioxidant, anti-inflammatory and cytotoxic activity of rose hips and the preserves (puree

219 veral cancer cell lines, as indicated by the cytotoxic activity of several novel small molecule IAP a

220 gnant cells confirmed the FAO inhibition and cytotoxic activity of ST1326, particularly on acute myel

221 ls, TpeL is a significant contributor to the cytotoxic activity of supernatants from cultures of tpeL

222 he fate of cancer cells that escape from the cytotoxic activity of T cells.

223 In vitro cytotoxic activity of the essential oil was determined o

224 Notably, the cytotoxic activity of the Fcmu-drug conjugate was mainta

225 ization of the synthetic hexapeptide and the cytotoxic activity of the hexapeptide conjugated to cisp

226 antitumor properties of trastuzumab with the cytotoxic activity of the microtubule-inhibitory agent D

227 The cytotoxic activity of the new ruthenium(II) and iridium(

228 The potent cytotoxic activity of the parasite appears to underlie d

229 and immunoassay studies demonstrate that the cytotoxic activity of the prodrug/Pd(0)-resin combinatio

230 Moreover, we have provided evidence that the cytotoxic activity of the proinflammatory cytokine IFN-g

231 A superior cytotoxic activity of the ruthenium complexes as compare

232 T-ALL cohorts, which correlated with similar cytotoxic activity of the SRC inhibitor KX2-391 and inhi

233 profile, antioxidant, anti-inflammatory and cytotoxic activity of the still insufficiently explored

234 a taxol derivative without compromising the cytotoxic activity of the taxol.

235 How the cytotoxic activity of these myeloid cells is regulated i

236 s in ES NSCLC patients express TNFalpha, the cytotoxic activity of this cytokine may confer improved

237 r decreases CCL5 expression and augments the cytotoxic activity of tissue-resident T and NK cells, wh

238 osis in colon carcinomas and potentiated the cytotoxic activity of TRAIL in RKO and HT29 cells and th

239 ancer immunity and enhance the HER2-targeted cytotoxic activity of trastuzumab emtansine.

240 portantly, TIDC were required to license the cytotoxic activity of tumor CD8(+) T cells, and in their

241 find that this mAb can enhance the in vitro cytotoxic activity of venetoclcax for CLL cells with hig

242 Content in cytolytic granules, as well as cytotoxic activity, of EBV- and CMV-specific CD8(+) T ce

243 The cytotoxic activities on a panel of human tumor cell line

244 PG-1 induces strong cytotoxic activities on cell membrane and acts as a pote

245 e highest antioxidant activity but the least cytotoxic activities on non-tumourous cell lines of NIH/

246 ly validated that afatinib has the strongest cytotoxic activity on BT474 (IC50 = 55.5 nM, BRCA2 and T

247 nsport abilities in artificial liposomes and cytotoxic activity on human cancer cell lines.

248 that are responsible for proinflammatory and cytotoxic activity on human vaginal epithelial cells.

249 rary showed an interesting dependency of the cytotoxic activity on the carbohydrate moiety, linker, p

250 intracellular granzyme B and showed stronger cytotoxic activity on the target cells.

251 Puree of R. canina exerted cytotoxic activity only against the HeLa cell line among

252 These defects were not simply due to reduced cytotoxic activity or increased cell death but, rather,

253 cells and, more importantly, sustains their cytotoxic activity over the long-term via persistent blo

254 ates with NEC (n = 14) exhibited significant cytotoxic activity (P = .008), and we identified in all

255 T3L-primed CD8(+) T cells displayed enhanced cytotoxic activity, polyfunctionality, and Ag sensitivit

256 nstrate that neither diminishing NK mediated cytotoxic activity (Prf1 mutation) nor NK cell depletion

257 t regulatory CD56(+)CD3(-) cells exhibit low cytotoxic activity, produce IL-22, and have an expressio

258 A preliminary model to explain the structure-cytotoxic activity relation is proposed where different

259 analogues 32 and 33 exhibit antimalarial and cytotoxic activities stronger than those of the marineos

260 onomeric preparation displayed hemolytic and cytotoxic activities suggesting that the monomer is the

261 ivated, expressed more TRAIL, and had strong cytotoxic activity, suggesting their contribution to the

262 ween IL-6 serum levels and the impairment of cytotoxic activity suggests the possibility that targeti

263 ed with M2 displayed lower degranulation and cytotoxic activity than NK cells cocultured with M1.

264 ations indicating that granzymes possess non-cytotoxic activities that might include such diverse bio

265 ex on different cancer cell lines indicate a cytotoxic activity that is unquestionably derived from t

266 expressing CD4(+) T cells exhibited a strong cytotoxic activity that restricted tumor development.

267 ances monocyte and macrophage phagocytic and cytotoxic activities through enhanced binding to CD16a u

268 Here we show that 8H exerts its cytotoxic activity through disruption of microtubule dyn

269 Both extracts exerted cytotoxic activity through dose-dependent impairment of

270 says to show that CX-5461 exerts its primary cytotoxic activity through topoisomerase II poisoning.

271 At steady state, AT1-ILCs displayed cytotoxic activity toward adipose tissue macrophages (AT

272 K cells from CS-exposed mice exhibit greater cytotoxic activity toward cells that express the NKG2D l

273 have been considered redundant due to their cytotoxic activity toward human neutrophils, each toxin

274 ved drugs were identified that showed potent cytotoxic activity toward retinoblastoma cell lines in v

275 p(-/-) versus wild type mice showed impaired cytotoxic activity toward tumor targets.

276 VLX600 shows enhanced cytotoxic activity under conditions of nutrient starvati

277 , their cell-selective antiproliferative and cytotoxic activities vary significantly.

278 This reduction of NK cytotoxic activity was accompanied by lower expression o

279 Additionally, a clone with low cytotoxic activity was associated with death and poor cl

280 dithiothreitol, indicating that the lack of cytotoxic activity was attributable to the formation of

281 The cytotoxic activity was determined in human cancer cell l

282 Their cytotoxic activity was evaluated according to protocols

283 The cytotoxic activity was evaluated using the MTT assay.

284 the agar disk diffusion method, and in vitro cytotoxic activity was examined by cell proliferation as

285 The peptide's cytotoxic activity was found to be markedly dependent up

286 However, VSV-FH cytotoxic activity was reduced by pretreatment of the ce

287 ow, but not in lymph nodes, where CAR T cell cytotoxic activity was reduced.

288 artially restored by IL-2 treatment, whereas cytotoxic activity was still defective in IL-2-activated

289 severity of illness and treatment modality, cytotoxic activity was strongly and inversely associated

290 Neutrophil cytotoxic activities were reduced in thrombocytopenic an

291 FN-gamma, TNF-alpha, and IL-2 and exhibiting cytotoxic activity, were associated with protection (p <

292 Without cytotoxic activity when administered as a single agent,

293 cription factors is present, but to lose all cytotoxic activity when both are not expressed.

294 identified a set of drugs that had enhanced cytotoxic activity when combined with IRAK inhibition.

295 jacent to the cationic sector exhibited high cytotoxic activity when tested against three different c

296 tics exhibit cytostatic activity rather than cytotoxic activity, which would be more desired.

297 ihydroisocoumarin-truncated analogs lose all cytotoxic activity while retaining the ability to inhibi

298 xtracts and evaluate their antimicrobial and cytotoxic activities with regard to some pathogenic micr

299 In particular, SeChry elicited a noteworthy cytotoxic activity with mean IC50 values 18- and 3-fold

300 racted from HTL-WW expressed potent CHO cell cytotoxic activity, with a LC(50) at 7.5% of HTL-WW.