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1 n, and dentine matrix resorption without any cytotoxicity.
2 ase suppresses neutrophil-induced tumor cell cytotoxicity.
3 mune synapse, lytic granule trafficking, and cytotoxicity.
4 macrophage cells, and in some cases, minimal cytotoxicity.
5 HL5, to require hRpn13 Pru and not UCHL5 for cytotoxicity.
6 s were shown to prevent aSyn aggregation and cytotoxicity.
7 ced physicochemical properties and low human cytotoxicity.
8 Among tested species, P. disiens exhibited cytotoxicity.
9 NK-induced necrosome signaling and resultant cytotoxicity.
10 mulation with cytokine production and direct cytotoxicity.
11 cytoskeleton significantly inhibited NK cell cytotoxicity.
12 whereas inhibiting TRPV3 exacerbated ERS and cytotoxicity.
13 anule polarization to the immune synapse and cytotoxicity.
14 olobenzodiazepines toward DNA and thus their cytotoxicity.
15 values in solution, strongly supports their cytotoxicity.
16 with longer alkyl chains enhancing analogue cytotoxicity.
17 g and found out that these peptides mediated cytotoxicity.
18 to be safe, preventing further GAG loss and cytotoxicity.
19 r serine proteases, and do not show relevant cytotoxicity.
20 sphorylation and reduces its aggregation and cytotoxicity.
21 tor functions, such as Ab-dependent cellular cytotoxicity.
22 proresolving mediators to influence NK cell cytotoxicity.
23 spectively, and without measurable host cell cytotoxicity.
24 the composite material does not advocate any cytotoxicity.
25 gative bacteria without inducting observable cytotoxicity.
26 ced the RFP intensity due to lactose-induced cytotoxicity.
27 nd genetic mechanisms influencing CAR T-cell cytotoxicity.
28 l release from hTF as potentially related to cytotoxicity.
29 analyse annexin A5 effects on Abeta-induced cytotoxicity.
30 e tolerance and lower CD8(+) T-cell-mediated cytotoxicity.
31 in deoxyuridine mitigated ER stress-induced cytotoxicity.
32 ) T cells, which mediated antibody-dependent cytotoxicity.
33 cancer cells promotes T cell-induced cancer cytotoxicity.
34 th specific GRNs exacerbating TDP-43-induced cytotoxicity.
35 d its capacity to rescue mitomycin C-induced cytotoxicity, accounting for two infrequent onset-hasten
39 ivities, such as antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis, are mediated by Fc
43 and mediate antibody-dependent cell-mediated cytotoxicity (ADCC) may play a dominant role in protecti
45 of HIV-specific antibody-dependent cellular cytotoxicity (ADCC) responses with protection from and d
47 ility of inducing Ab-dependent cell-mediated cytotoxicity (ADCC), complement deposition, and compleme
48 to mediate antibody-dependent cell-mediated cytotoxicity (ADCC), during HCV infection is poorly defi
54 ticles exhibited enhanced ultrasound-induced cytotoxicity against both prostate cancer cell lines.
57 Staphylococcus aureus MIC = 5 mg/mL) and no cytotoxicity against carcinogenic and non-tumour primary
58 86, IC(50) 0.7 nM, HDAC1), 25-fold increased cytotoxicity against five human cancer cell lines, and u
59 These novel ADCs displayed sub-nanomolar cytotoxicity against HER2-expressing cancer cells, while
61 at show enhancements in selective anticancer cytotoxicity against MCF-7 breast cancer cells in vitro.
62 AGT1 inhibitory activity, CPPB does not show cytotoxicity against normal cells and a series of cancer
63 y blasts from AML patients, while showing no cytotoxicity against normal PBMCs, NIH3T3, and HEK293 ce
64 reducible crosslinked MLNPs exhibited higher cytotoxicity against TNBC and breast cancer cells which
65 erase (NAMPT), synergizes with MMS to induce cytotoxicity and Aag(-/-) cells are resistant to this co
68 well as biological investigations including cytotoxicity and apoptotic assays, and quantitative poly
69 This leads to substantial levels of cellular cytotoxicity and breakdown of tight junctions between ce
71 large clones overexpress genes implicated in cytotoxicity and characteristic of effector memory T cel
73 lling to promote antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity throu
74 ificantly reduced G9Calpha(-/-)CD8(+) T-cell cytotoxicity and dendritic cell-induced proliferation, t
75 ad, soft bread and biscuits), evaluate their cytotoxicity and determine their suitability as function
77 exes, we used a series of time-kill studies, cytotoxicity and hemolysis assays, as well as whole-cell
78 ddition, these novel carbons have negligible cytotoxicity and high biocompatibility for human cells,
79 17-30)] through in silico analysis to reduce cytotoxicity and improve the anti-inflammatory activity
80 wed, with their structures, cancer cell line cytotoxicity and in vivo antitumor activity, structure-a
81 ogically cold melanoma to both induce direct cytotoxicity and increase immune responses in the contex
82 pendently of both O(6)-methyl guanine adduct cytotoxicity and MUTYH-dependent glycosylase activity.
83 d in brain plaques are viewed as triggers of cytotoxicity and neuroinflammation in Alzheimer disease
84 formed molecular biology studies revealed no cytotoxicity and no influence of engineered carbon nanom
85 line, RTgill-W1, to investigate pH-dependent cytotoxicity and permeation of IOCs across cultured epit
88 effect of cottonseed ethanol extracts on the cytotoxicity and regulation of anti-inflammatory tristra
89 erivatives have been studied regarding their cytotoxicity and virus-inhibiting activity against influ
91 ides have continuously cited minimal to zero cytotoxicity and, where tested, sufficient drug release
93 the multidrug-resistant K1 strain, in vitro cytotoxicity, and cardiotoxicity and were addressed thro
95 ased rates of Mn membrane transport, reduced cytotoxicity, and increased selectivity for Mn over calc
97 ic antibody-dependent phagocytosis, cellular cytotoxicity, and natural killer cell activation were as
98 to determine of nutritional value, in vitro cytotoxicity, and oxidative stress parameters in cells o
99 pairments with increased amyloidogenesis and cytotoxicity, and this dimer was then used in a screenin
100 s against intestinal inflammation, potential cytotoxicity, anti-inciting action, and suppression of a
101 subset of benzodiazepines exacerbated p-tau cytotoxicity apparently via enhancing p-tau aggregation.
105 ap and coat tumor cells and shield them from cytotoxicity, as mediated by CD8(+) T cells and natural
108 Standard degranulation and chromium release cytotoxicity assays confirm the ability of cryopreserved
111 sis, with biological activity as assessed by cytotoxicity assays performed in adenocarcinoma human al
114 he present study, using liposome-leakage and cytotoxicity assays, LC-MS/MS-based proteomics, and CCF-
119 s often recommended because of the potential cytotoxicity associated with EdU during longer incubatio
121 cells is associated with diminished natural cytotoxicity but enhanced antibody-dependent cellular cy
122 e of autophagy upregulated radiation-induced cytotoxicity but only modestly affected the levels of ce
123 contributed to both CD8+ and CD4+ CAR T cell cytotoxicity but was not required for in vitro or in viv
124 ne kinase inhibitors that inhibit CAR T-cell cytotoxicity by impairing T-cell signaling transcription
125 pulp fibroblasts (FP6) were used to evaluate cytotoxicity by incorporating MTT dye, and genotoxicity
126 es to the surface of cancer cells and induce cytotoxicity by peripheral blood mononuclear and enginee
127 iew, we discuss how NKDs that affect NK cell cytotoxicity can be approached in the clinic and laborat
128 power for downstream cancer, and assays for cytotoxicity can predict deleterious health effects.
129 atumumab, which, in addition to its inherent cytotoxicity, can be radiolabeled with tracers for imagi
131 (IC(50) = 0.27 muM), significantly decreased cytotoxicity (CC(50) = 156.8 muM), and low in vivo toxic
133 l cytotoxic effects, thus departing from the cytotoxicity-centric paradigm previously assigned to HDA
136 ternalization, transgene expression, and low cytotoxicity compared to commercial controls for several
137 al due to its reduced removal time and lower cytotoxicity compared to the other treatment options.
139 f natural sunlight) decreased the calculated cytotoxicity contributed by dihaloacetonitrile-FP in mos
140 s such as high cellular internalization, low cytotoxicity, controllable pharmacokinetics and biodistr
142 e water sorption (SOR), solubility (SOL) and cytotoxicity (CYTO) of experimental adhesives containing
144 PRMT5 activity synergistically enhances Gem cytotoxicity due to the accumulation of excessive DNA da
145 istone deacetylase HDAC3 inhibits CD8 T cell cytotoxicity early during activation and is required for
148 strain HF_1994 displayed a striking lack of cytotoxicity, even exerting a cytoprotective effect on a
151 ncertain significance affecting a lymphocyte cytotoxicity gene or the perforin variant A91V was obser
153 especially its capacity for antigen-directed cytotoxicity, has become a central focus for engaging th
154 he assays conducted include, Ag-Phen induced cytotoxicity (IC(50) 4.5 muM at 72 h) and 2-fold ROS gen
156 that alpha-syn aggregates attenuate NK cell cytotoxicity in a dose-dependent manner and decrease the
157 le in DNA repair, AAG-initiated BER promotes cytotoxicity in a process dependent on poly (ADP-ribose)
160 ing how DNA damage response inhibitors cause cytotoxicity in cancer cells is crucial to their further
162 imary cells, potentiated gemcitabine and JQ1 cytotoxicity in cell culture, and Gem + TSA + JQ1 inhibi
166 A-approved PARP inhibitor, could enhance the cytotoxicity in HCC cells with a lower BRCA1 expression,
167 UV-A dosage decreased the aflatoxins-induced cytotoxicity in HepG2 cells, and no significant aflatoxi
169 ility, prolonged drug release and remarkable cytotoxicity in human pancreatic cancer cell lines and K
172 ylosoxidans isolates from CF patients induce cytotoxicity in macrophages, suggestive of a pathogenic
174 nfounding bovine serum amine oxidase-induced cytotoxicity in mechanistic studies of the roles of poly
176 wed that miR-124 protects against As-induced cytotoxicity in neural cells with concomitant suppressio
181 ical studies suggest that Amiodarone induces cytotoxicity in several types of cancer cells, thus maki
182 the landscape of microRNAs with significant cytotoxicity in the context of glioblastoma (GBM), we pe
184 abolic (microsomal) stability, and promising cytotoxicity in three cancer cell lines (DU145, HeLa, A5
187 for bio-applications, we investigated their cytotoxicity in vitro as well as their utilization as su
189 /-)) MEFs, but this blockade had no additive cytotoxicity in WT MEFs, suggesting the cytotoxicity is
190 y linked to a cationic polymer induce strong cytotoxicity, including reduced cellular viability and s
191 show that this pathway is required to resist cytotoxicity induced by the cytokines IFNgamma and TNF.
192 study provides mechanistic insights into the cytotoxicity instigated by KP372-1 and lays an essential
193 nsition metals have been employed, but their cytotoxicity is an issue and hence must be reduced, typi
195 tive cytotoxicity in WT MEFs, suggesting the cytotoxicity is due to MUTYH interactions with MNNG-indu
198 Such polymorphism can dramatically influence cytotoxicity, leading to much interest in the conditions
200 tiple targets, together with its outstanding cytotoxicity, make complex 1 a valuable candidate in the
201 e concentration (EC(50)) against Shiga toxin cytotoxicity measured in a cell protein synthesis assay.
203 sitive and 100 negative) were tested by cell cytotoxicity neutralization assay (CCNA), C. diff Quik C
204 d then prioritized and guided by cancer cell cytotoxicity, NMR-based SMART 2.0, and MS(2)-based molec
208 breaks, contributes strongly to the overall cytotoxicity of anthracyclines, and structures containin
211 us therapeutics directly linking Dox and TF, cytotoxicity of CDT resulted from nuclear entry by Dox,
214 d for the higher anti-proliferative activity/cytotoxicity of HE extracts on Caco-2 and HepG2 cells as
217 ate defense against pathogens through direct cytotoxicity of infected cells and are the predominant i
221 review assesses, in the first instance, the cytotoxicity of MOFs (particularly those used for variou
222 ng ability, the effect on enamel surface and cytotoxicity of novel tooth-whitening formulations conta
225 cell culture models are widely used to study cytotoxicity of RRVs, but results have been contradictor
229 ion of immunosuppressive cells, the improved cytotoxicity of T lymphocytes, decreased inhibitory and
230 accumulation of genomic 8-oxodG and reduced cytotoxicity of TH588, in line with the notion that mito
232 d inhibitor vemurafenib, which decreased the cytotoxicity of the drug in BRAF(V600E) melanoma cells.
233 transcription-blocking agents, and that the cytotoxicity of the G-quadruplex ligand pyridostatin inv
234 proliferation, and improved the synergistic cytotoxicity of treatment with the alkylating agent temo
238 driven by HLA class I (essential for T-cell cytotoxicity) or class II (important for T-cell helper r
240 class I and/or II >99%, complement-dependent cytotoxicity panel reactive antibody [CDC PRA+], C1q+) h
241 1 (G0, G1, G2, G0G0, G0G1, or G0G2) on known cytotoxicity phenotypes, including reduced viability, in
242 o a new generation with high solubility, low cytotoxicity, potent broad-spectrum sterilizing activity
243 RR aqueous emulsions were examined for cell cytotoxicity, proliferation, redox state and migration u
249 analysis, and assessment of aggregation and cytotoxicity revealed that the TTR segment inhibits Abet
250 ated with inherited defects in cell-mediated cytotoxicity, serves as a prototypical CSS for which the
251 infection of wastewaters increased mammalian cytotoxicity several orders of magnitude, with chloramin
252 Ss, including impairment of granule-mediated cytotoxicity, specific viral infections, excess IL-18, a
258 anostructure architecture exhibits less cell cytotoxicity than conventional SNAs without a decrease i
261 nable protection while minimizing epithelial cytotoxicity that can often accompany an inflammatory re
263 ysis of FBIC efficacy included evaluation of cytotoxicity, tissue penetration, foam stability, temper
264 as conducted to evaluate in vitro fibroblast cytotoxicity to a solution of MMC (0.2 mg/ml) and 1% pre
265 -1 micelles were observed to bind and induce cytotoxicity to cancer cells through interaction with CC
266 otericin B doses, while exhibiting much less cytotoxicity to healthy macrophages than amphotericin B.
269 t-bound complexes and correlate the reported cytotoxicity to the peptide oligomeric structures and th
271 ig IgM/IgG binding, and complement-dependent cytotoxicity to wild-type (WT), alpha1,3-galactosyltrans
272 Moreover, the cryogels showed negligible cytotoxicity toward murine fibroblasts and prevented act
274 -specific TCRs showed IFNgamma secretion and cytotoxicity towards EBV-LMP2-expressing malignant cell-
275 ound that narciclasine displays preferential cytotoxicity towards PEL at low nanomolar concentrations
278 id not exert significant oxidative stress or cytotoxicity upon incubating with differentiated SHSY5Y
279 estigated druggable mechanisms of CAR T-cell cytotoxicity using >500 small-molecule drugs and genome-
281 l-cell lung cancer (NSCLC) cells showed that cytotoxicities varied by more than three orders of magni
284 ed cellular detachment from the surface, and cytotoxicity was monitored using the trypan blue life/de
285 cells, and no significant aflatoxin-induced cytotoxicity was observed at UV-A dose of 1,200 mJ/cm(2)
291 drug screen revealed significantly enhanced cytotoxicity when NR-160 was used in combination with ep
292 y was assessed by production of IFNgamma and cytotoxicity when stimulated with EBV-LMP2-expressing ce
293 phosphomimetic) reduces ischemic proteo- and cytotoxicity, whereas a phospho-silenced CHIP-S20A ampli
296 phagy for survival and displayed synergistic cytotoxicity with the poly (ADP-ribose) polymerase (PARP
297 BD-14270 (8), showed a marked improvement in cytotoxicity, with 3-fold and 58-fold improvements in se
298 tor of cancer cell sensitivity to CAR T-cell cytotoxicity, with potential for pharmacological targeti
300 , we hypothesized that inhibiting CD8 T-cell cytotoxicity would reduce disease severity in patients.