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1 ochondria as the potential site of action of daidzin.
2  (DOPAL) which accumulate in the presence of daidzin.
3 s well, which accumulates in the presence of daidzin.
4 s and mediates the antidipsotropic effect of daidzin.
5  a series of synthetic structural analogs of daidzin.
6 bited by ALDH inhibitors chloral hydrate and daidzin.
7                                              Daidzin, a major active principle of an ancient Chinese
8                                    Synthetic daidzin added to the RP extract acquires the bioavailabi
9                             The structure of daidzin/ALDH2 in complex at 2.4 A resolution shows the i
10  finding that it is bacterially derived from daidzin, an isoflavone abundant in soy foods, led to the
11                                              Daidzin analogs that suppress hamster ethanol intake als
12                                              Daidzin analogues that potently inhibit ALDH-2 but have
13                                              Daidzin analogues that potently inhibit ALDH-2 but have
14 +/-0.02 min(-1), 4.54+/-0.32 min, 60 min for daidzin and 0.16+/-0.02 min(-1), 2.28+/-0.11 min, 60 min
15 oked sample, while increased the contents of daidzin and daidzein and decreased the content of genist
16                                              Daidzin and daidzein shortened alcohol-induced sleep tim
17 lity of established models in explaining the daidzin and daidzein transformation to equol as a functi
18          At 24 h of fermentation, amounts of daidzin and daidzein were influenced by all factors.
19 mount (X3) on transformation of isoflavones (daidzin and daidzein) to equol in soymilk fermented with
20  ALDH-2 and MAO, we prepared 44 analogues of daidzin and determined their potencies for ALDH-2 and MA
21 ization mass spectrometry was used to detect daidzin and genistin after solid-phase extraction of the
22 on process significantly lowered contents of daidzin and genistin in 60min cooked sample, while incre
23 new strategy to isolate daidzein, genistein, daidzin and genistin in soybean.
24 n, genistein, biochanin A, and two of which, daidzin and genistin, are glycosilated, in lentils and o
25 earity ranging from 0.1 to 5mg/L, except for daidzin and genistin, for which it ranged from 0.1 to 10
26                                              Daidzin and its active analogs, at concentrations that s
27 s possibility, we have studied the effect of daidzin and its analogs on 5-HT and DA metabolism in iso
28                                   Effects of daidzin and its structural analogues on the activities o
29          While at 48 h, all factors affected daidzin and only temperature affected daidzein.
30 rom the graded dose-response curves for pure daidzin and RP extract daidzin are 23 and 2.3 mg per ham
31  we synthesized more structural analogues of daidzin and tested and compared their antidipsotropic ac
32                                    Puerarin, daidzin, and daidzein are 3 major isoflavonoid compounds
33 gh 48 h for compounds such as medicarpin and daidzin; and a lesser delayed and protracted response st
34 ponse curves for pure daidzin and RP extract daidzin are 23 and 2.3 mg per hamster per day, respectiv
35  A resolution shows the isoflavone moiety of daidzin binding close to the aldehyde substrate-binding
36 nts for the fact we previously observed that daidzin can suppress ethanol intake of this species with
37                                       Plasma daidzin concentration-time curves determined in hamsters
38 den hamsters was compared with that of crude daidzin contained in a methanol extract of Radix puerari
39 xtract cannot be accounted for solely by its daidzin content (22 mg/g).
40         This, together with the finding that daidzin does not affect the rates of mitochondria-cataly
41 d ALDH-2 inhibition by structural analogs of daidzin established a link between these two activities
42 DH2 and compared them to the ALDH2 inhibitor daidzin for selectivity against five ALDH1/2 isoenzymes.
43  procedure generally increased the amount of daidzin, genistin and daidzein, but decreased that of ge
44 quadratic on the length, moisture and on the daidzin, genistin and genistein content; linear on the f
45 imultaneous quantification of 6 isoflavones (daidzin, genistin, daidzein, genistein, formononetin and
46 genistein, and glycitein), and 9 glucosides (daidzin, genistin, glycitin, acetyldaidzin, acetylgenist
47 stein), their corresponding glycoside forms (daidzin, glycitin and genistin), and acetyl and malonyl
48 .p.injection indicate that the crude extract daidzin has approximately 10 times greater bioavailabili
49 ion for both the specificity and affinity of daidzin (IC50 =80 nM) and the affinity of analogues with
50  the methanol extract of RP assist uptake of daidzin in golden hamsters.
51 cytosolic isozyme is completely resistant to daidzin inhibition.
52                                              Daidzin is also a potent and selective inhibitor of huma
53 t appears that the antidipsotropic action of daidzin is not mediated by 5-HT (or DA) but rather by it
54 take-suppressive (antidipsotropic) action of daidzin is not mediated by the monoamines but rather by
55                                              Daidzin is the active principle in a herbal remedy for "
56                                              Daidzin is the major active principle in extracts of rad
57                  These results show that (i) daidzin is the major active principle in methanol extrac
58 l product 7-O-glucosyl-4'-hydroxyisoflavone (daidzin), isolated from the kudzu vine ( Peruraria lobat
59                                        Thus, daidzin may act by inhibiting 5-HT and DA metabolism.
60 ive, are consistent with the hypothesis that daidzin may act via the mitochondrial MAO/ALDH pathway a
61 ween these two activities and suggested that daidzin may suppress ethanol intake by inhibiting ALDH-2
62 e suppression and raise the possibility that daidzin may, in fact, suppress ethanol intake of golden
63                      The dose effect of pure daidzin on the suppression of ethanol intake in Syrian g
64 spectrometry failed to detect even traces of daidzin or genistin in plasma collected 1, 2, and 8 h af
65 mg of one of the isoflavone beta-glycosides (daidzin or genistin) or 250 mL soymilk containing mainly
66  hamsters administered various doses of pure daidzin or RP extract by i.p.injection indicate that the
67                                              Daidzin potently inhibits the formation of 5-hydroxyindo
68 or pure and crude daidzin using bioavailable daidzin rather than administered dose gives a single cur
69                               In addition to daidzin, six other isoflavones were identified in the RP
70 AC) formation by six structural analogues of daidzin suggested a potential link between these two act
71                   Recent studies showed that daidzin suppresses ethanol intake in ethanol-preferring
72                 Thus, the mechanism by which daidzin suppresses ethanol intake in golden hamsters cle
73 quires the bioavailability of the endogenous daidzin that exists naturally in the extract.
74                  Recently we have shown that daidzin, the major active principle of an ancient herbal
75 the dose-response effects for pure and crude daidzin using bioavailable daidzin rather than administe
76 indicated that the suppression of the BAC by daidzin was due mainly to delay of stomach emptying.
77                     At least 10% of ingested daidzin was excreted in urine as equol conjugate in one
78             BACs also receded more slowly if daidzin was fed to the animals.
79                                         When daidzin was given to animals intragastrically with the e
80                                 Genistin and Daidzin were the major isoflavones in all samples.