ライフサイエンスコーパス: deactivation

1 ude, without affecting the change in current deactivation.

2 ies, whereas Au/AC does not recover from the deactivation.

3 in the excited-state manifold leads to rapid deactivation.

4 enation: activation, stable performance, and deactivation.

5 pagating alkyl radical capable of reversible deactivation.

6 ates of hydrolysis to glucose without enzyme deactivation.

7 tors that affect the rates of activation and deactivation.

8 monized to secure a low rate of nonradiative deactivation.

9 by the GPER/RhoA/myosin axis and induces YAP deactivation.

10 eactivation discussions and increased device deactivation.

11 n In(0) coincides with the onset of catalyst deactivation.

12 S domain truncations mainly affected channel deactivation.

13 sor movement, which indirectly slows current deactivation.

14 Subsequent self-oxidation eventually causes deactivation.

15 the pore gate and the voltage sensor during deactivation.

16 terised by slower desensitisation and faster deactivation.

17 forated-patch conditions and slowed receptor deactivation.

18 ation, S140G and V141M, drastically slow IKs deactivation.

19 el activation voltage and an accelerated HCN deactivation.

20 s highly robust with no evidence of catalyst deactivation.

21 * and CO* intermediates, leading to catalyst deactivation.

22 that lead to catalytic activity and material deactivation.

23 e scales of activation, desensitization, and deactivation.

24 creasing competition of nonradiative surface deactivation.

25 ein kinase (MAPK), and nitric oxide synthase deactivation.

26 ensor-pore coupling, thereby slowing current deactivation.

27 tization activities and avoid rapid catalyst deactivation.

28 GTPase-activating proteins, potentiating Gq deactivation.

29 13 catalyst cannot overcome owing to thermal deactivation.

30 fication of kinetics in ionic activation and deactivation.

31 catalysis to proceed without sulfur loss and deactivation.

32 results in a faster structural collapse and deactivation.

33 voltage dependence of channel activation and deactivation.

34 -length F508del-CFTR and accelerated channel deactivation.

35 ays an important role in preventing catalyst deactivation.

36 tribute insufficient activation energy delay deactivation.

37 Wnt pathway antagonist that blocks GSK3beta deactivation.

38 dizing (2) PC(.+) intermediate for efficient deactivation.

39 and either due to low reactivity or catalyst deactivation.

40 ted states of carbon dots from non-radiative deactivation.

41 nd 2000 hours on stream without any catalyst deactivation.

42 eletion drastically accelerates hERG channel deactivation.

43 approximately 2H2O) transitions and SCO-deactivation (1)).

44 es in discussions (41 [14%] vs. 26 [12%]) or deactivation (33 [11%] vs. 26 [12%]).

45 with decision-making resulted in significant deactivation across both the VLPFC and DLPFC (P < 0.05).

46 uring sustained ATP application and receptor deactivation after ATP washout, and makes the receptor p

47 ed only by covalent attachment of amino acid deactivation agents to residual activated carboxy groups

48 physiology, including increased task-induced deactivation, altered limbic connectivity and increased

49 here were no differences in conversations or deactivations among decedents.

50 ighest activity and stability, whereas rapid deactivation and a low catalytic activity were observed

51 RK2-mutated carcinomas yielded frequent TP53 deactivation and a remarkably high tumor mutation burden

52 o functional imaging evidence supporting DMN deactivation and deconnection during high-demanding cogn

53 tervention increased conversations about ICD deactivation and goals of care.

54 Unusual Pd deactivation and inhibition pathways were observed in a

55 taneous IPSCs, consistent with the idea that deactivation and local GABA actions drive delta spontane

56 Glycogen synthase kinase 3beta (GSK3beta) deactivation and nuclear localization of beta-catenin cr

57 and voltage sensor-pore coupling to slow IKs deactivation and provide a key step toward developing me

58 ently accelerate the rates of building block deactivation and reactivation.

59 ive responses to infection, but their prompt deactivation and removal are essential for limiting tiss

60 continuous flow approach overcomes catalyst deactivation and scale dependence issues that can be a p

61 This enables integrin deactivation and supports cell migration.

62 elopment and increase the rate of motor unit deactivation, and (2) blood flow reperfusion (REP) would

63 ge dependence of activation, regulating slow deactivation, and modulating C-type inactivation of Kv11

64 eased IHVR, enhanced NO bioavailability, HSC deactivation, and reduced intrahepatic microthrombosis.

65 ntal" microstate 3 as a sign of deeper local deactivation, and the reduced presence of the "occipital

66 nt kinetics of activation, inactivation, and deactivation; and bimodal recovery from inactivation.

67 Therefore, the rates of activation/deactivation are determined by both the electronic prope

68 SNAREs undergo cycles of activation and deactivation as membranes move through the fusion cycle.

69 ult mode network (i.e., greater task-induced deactivation) as well as greater FA in white matter area

70 o their poor activity, sulfur loss and rapid deactivation at elevated temperature.

71 By measuring slow activation and deactivation at steady state we found the "true" mode-sh

72 at ASICs show such steeply agonist-dependent deactivation because of strong cooperativity in proton b

73 property underlying the universal, ultrafast deactivation behavior of eumelanin in response to photoe

74 2-containing receptors also exhibited faster deactivation but unaltered steady-state properties.

75 ) was shown to rescue p53 from mdm2-mediated deactivation, but the mechanism is unknown.

76 tic deceleration of current and fluorescence deactivation, but these effects are attenuated upon disr

77 enzymes require protection to prevent their deactivation by bleach.

78 nhanced Maxwell-Wagner polarization.Catalyst deactivation by coke deposition is a major drawback in i

79 isms via spillover, and higher resistance to deactivation by coking that plagues many industrial cata

80 ytic performance and increased resistance to deactivation by coking, compared to its microporous coun

81 block in glycolysis associated with monocyte deactivation by endotoxin, a process contributing to imm

82 TOR) signaling controls the dynamics of IRE1 deactivation by regulating ER-mitochondria physical cont

83 FOX and IL-12 gene therapy following stromal deactivation by RLN gene therapy completely cured establ

84 All drugs reached more than 99.00% deactivation by the end of 28-day period.

85 ion in protecting Bt subsp. Kurstaki against deactivation by UV-A irradiation was measured, so that s

86 es and quantifies the states involved in the deactivation cascade after light absorption.

87 However Au catalysts suffer from progressive deactivation caused by auto-reduction of Au(I) and Au(II

88 We apply reversible-deactivation chain transfer in the bifunctional ROCOP sy

89 Reversible-deactivation chain transfer is a viable strategy to incr

90 ions in catalysis, as well as activation and deactivation characteristics covering important literatu

91 aintenance of this, along with maintained DM deactivation, characterizes successful ageing and may ex

92 transient binding sites slows activation and deactivation, consistent with slower glutamate binding a

93 prove Implantable Cardioverter-Defibrillator Deactivation Conversations [WISDOM]; NCT01459744).

94 vanced therapies, the intervention increased deactivation discussions (32 [25%] vs. 16 [11%]; odds ra

95 ention and automatic reminders increased ICD deactivation discussions and increased device deactivati

96 s were proportion of patients: 1) having ICD deactivation discussions; and 2) having the shocking fun

97 cidosis on macroscopic current amplitude and deactivation displayed different sensitivities to proton

98 ntrol of the lifetime of rod PDE6 activation/deactivation during visual signaling, as well as providi

99 he activation (E(A) = 50.3 +/- 7 kJ/mol) and deactivation (E(D) = 62.23 +/- 3 kJ/mol) energies of hyd

100 t plant defenses through biochemical defense deactivation, effector-mediated suppression of defense s

101 dicted on the basis of simple C-H activation/deactivation effects exerted by proximal substituents.

102 ond, the coral species had generally greater deactivation energies for net and gross primary producti

103 etic capacity (i.e., activation energy, Ea ; deactivation energy, Hd ; entropy parameter, DeltaS) or

104 Deactivation extended into brain areas encoding low-leve

105 on of the TM domain, and that activation and deactivation follow a cyclic pathway, including-in addit

106 mplex behavior to the CoRA dependence of Env deactivation following FI binding.

107 anced NMDA receptor agonist potency and slow deactivation following rapid removal of glutamate, as oc

108 rate perturbations associated with catalyst deactivation from kinetic profiles when the quantity of

109 However, whether SNr deactivation has an essential role driving or regulating

110 molecular determinants of mouse melanopsin's deactivation have been characterized (i.e., C-terminal p

111 m of ion-pairing, ring-opening, and catalyst deactivation have been studied in the condensed phase wi

112 The relative deactivation in anterior cingulate cortex, informed by o

113 e active sites within the composite.Catalyst deactivation in fluid catalytic cracking processes is un

114 During self-touch, we instead found deactivation in insula, anterior cingulate cortex, super

115 SF) process is responsible for excited state deactivation in isoindigo derivatives.

116 trates the efficacy of surgical trigger site deactivation in migraine patients.

117 modulation may play a critical role in mPFC deactivation in neuropathic pain and underlie the mPFC-s

118 h the patterns of Default Mode Network (DMN) deactivation in Obsessive Compulsive Disorder (OCD) in t

119 binant and native ASICs show extremely rapid deactivation in outside-out patches when jumping from a

120 f activation in the default mode network and deactivation in the frontoparietal attention network.

121 We investigated the mechanisms of mPFC deactivation in the rat spared nerve injury (SNI) model

122 C, when compared with OCD, had a significant deactivation in two anterior nodes of the DMN (medial fr

123 tal and cerebellar regions, and task-related deactivations in default mode network (DMN) areas.

124 ectivity", or from the consistent and robust deactivations in task-based fMRI (tb-fMRI), here referre

125 ot of Panax ginseng, slows the rate of hERG1 deactivation, induces channels to open at more negative

126 Irreversible catalyst deactivation involved C-H insertion of Pd into BippyPhos

127 This mechanical deactivation is mediated by the GPER/RhoA/myosin axis an

128 example of a ligand-gated ion channel whose deactivation is sensitive to agonist concentrations that

129 initiator effects on the rates of activation/deactivation is still limited.

130 rordinate, dichotomous pattern of activation/deactivation, is common across a variety of task demands

131 issociation or PLC-beta3-potentiated Galphaq deactivation, is not sufficient to explain the observed

132 diheteromeric GluN1/2B receptors with slower deactivation kinetics is decreased.

133 Transmitter diffusion, rebinding, or slow deactivation kinetics of channels are candidates.

134 antly more negative voltages and with slower deactivation kinetics than the corresponding WT channels

135 hERG1a and hERG1b RNA yielded channels with deactivation kinetics that reached a plateau and were di

136 iheteromeric GluN1/2A/2B receptors with fast deactivation kinetics, whereas expression of diheteromer

137 IK,L also showed complex activation and deactivation kinetics, which we faithfully reproduced by

138 ndance at synapses and speeds up the channel deactivation kinetics.

139 5 ms), whereas it only had a minor effect on deactivation kinetics.

140 voltage dependence of activation, and slowed deactivation kinetics.

141 Structure (XANES) spectroscopy confirms that deactivation largely occurs through the migration of Ni

142 nd recurrent states of network activation or deactivation mainly encompassing lateral or medial assoc

143 ficantly improved upon, suggesting catalytic deactivation may be a serious issue to be understood and

144 Here, we report a deactivation mechanism of HIF-1 and several other oncoge

145 talyst rapidly deactivates on-stream and the deactivation mechanism remains unclear.

146 suggests H atom intercalation as a catalytic deactivation mechanism.

147 s, we reveal the opposite process as a novel deactivation mechanism: nanoparticles rapidly lose activ

148 The optical properties and excited state deactivation mechanisms of selected compounds were studi

149 ization precision, while the photoactivation/deactivation mode offers slower imaging, with further im

150 c inhibition of SNr cells (mimicking the SNr deactivation observed during an active avoidance behavio

151 Receptor deactivation occurred with time constants of ~40 and ~90

152 n azametallacycle (4) suggests that catalyst deactivation occurs with a large excess of cyanamide ove

153 The deactivation of 2D-Mo(2)CO(x)/SiO(2) under DRM condition

154 he activation and slows the inactivation and deactivation of a second potassium conductance, G(K(LV))

155 n of more reactive palladium catalyst versus deactivation of a substrate by its protonation.

156 t, compared with OCD, HC had a significantly deactivation of a widespread brain network (superior fro

157 I3K-Akt targets, 75% could be explained by a deactivation of adenylate-uridylate-rich element (ARE)-b

158 the three-carbon bridge leads to the partial deactivation of anomeric effects.

159 ion in root hydraulic conductivity driven by deactivation of aquaporins, and downstream limitation of

160 NMDAR- and Ca(2+)-permeable AMPAR-dependent deactivation of BCR in hippocampal but not cortical neur

161 tor, responsible for both the perception and deactivation of bioactive SLs.

162 slow opening/closing of stomata, activation/deactivation of C3 cycle enzymes, and up-regulation/down

163 al challenges, for example, those related to deactivation of cardiac devices, such as pacemakers, def

164 he expression level of CAs and/or stimulated deactivation of CAs may correspond with lower photosynth

165 NP provided information about the origins of deactivation of catalytic NPs and the effects of various

166 olysulfides triggered the persulfidation and deactivation of cleaved caspase-3.

167 that OCD patients had difficulties with the deactivation of DMN even when the non-rest condition inc

168 xy-group-terminated OEG-SAMs, only a partial deactivation of EDC/NHS-activated zwitterionic carboxy g

169 their lifetime, probably due to nonradiative deactivation of excited states by N-H bonds.

170 SHP2 effects were mediated through deactivation of fibrosis-relevant tyrosine kinase and se

171 s well as differentiated tissue, and through deactivation of G2/M cell-cycle checkpoint allows the ce

172 ng NO3(-) addition, followed within hours by deactivation of genes encoding enzymes for chlorophyll b

173 n-coupled receptor signaling by accelerating deactivation of Gi/o alpha-subunits, several neurologica

174 dministration also caused activation of Akt, deactivation of GSK3beta and activation of ERK1/2 in the

175 Slow deactivation of hERG channels is critical for preventing

176 using an increase in histone acetylation via deactivation of histone deacetylases (HDACs).

177 pants displayed the expected glucose-induced deactivation of hypothalamic activation, whereas patient

178 oltage dependence of activation and slow the deactivation of I(Ks).

179 ull-length F508del-CFTR and slightly delayed deactivation of individual F508del-CFTR Cl(-) channels.

180 h subsequent SAMHD1 T592 phosphorylation and deactivation of its antiviral activity.

181 Deactivation of LBPA using anti-LBPA antibody significan

182 Deactivation of mPFC output is causally correlated with

183 s well as the hydrothermal stability and the deactivation of nanoporous catalysts.

184 n in the tumor cells in mice, which leads to deactivation of NF-kappaB pathway, and consequently inhi

185 ly slowed the activation but accelerated the deactivation of NsVBa, whereas the local anesthetic drug

186 ted protein kinase, which was accompanied by deactivation of oncogenic mechanistic target of rapamyci

187 cross-coupling generally requires a designed deactivation of one nucleophile towards transmetallation

188 NAAA catalyzes the hydrolytic deactivation of palmitoylethanolamide (PEA), a lipid-der

189 To overcome deactivation of Pd-based catalysts at high temperatures,

190 and induced pre-BCR signaling, resulting in deactivation of PI3K/Akt signaling.

191 high workload conditions is associated with deactivation of prefrontal regions important for attenti

192 tal pH values) that may hold promise for the deactivation of proteinaceous contaminants.

193 However, the gradual deactivation of redox mediators during repeated cycling

194 thermolability of Rca is responsible for the deactivation of Rubisco and reduction of photosynthesis

195 Here, we unraveled the deactivation of secondary amines by undesired aldol reac

196 phasic manner through direct interaction and deactivation of SHP2, thus blocking the gp130 (Y759)-med

197 Coking leads to the deactivation of solid acid catalyst.

198 The ultrafast partial deactivation of the (3) MLCT state constitutes a loss ch

199 n, as well as for those that require minimal deactivation of the (3)MLCT state through low-lying meta

200 Deactivation of the 3DOM Co3O4-supported Au-Pd, Pd-CoO,

201 ights they provide as to both activation and deactivation of the antibacterial.

202 tal evidence for S-glutathionylation induced deactivation of the Arabidopsis thaliana kinase BRASSINO

203 rationalized on the basis of an acid-induced deactivation of the C-H bonds alpha to nitrogen toward H

204 The profound and widespread deactivation of the cortex in the unconscious states of

205 Our findings demonstrate steady-state deactivation of the default network under acute hypoxia,

206 ontrol children), more severe impairments in deactivation of the DMN were associated with greater inc

207 ation of the posterior parietal cortex, less deactivation of the dorsolateral prefrontal cortex and t

208 pted into micropatterned landscapes by photo-deactivation of the enzyme.

209 ure, the transition states of the activation/deactivation of the growing polymer chain, a key equilib

210 istry and solar energy conversion, but rapid deactivation of the initial metal-to-ligand charge trans

211 and by irradiation with 400 nm light through deactivation of the ligand by photo-oxidation.

212 istance in Gram-negative bacteria, i.e., the deactivation of the most widely used antibiotics, beta-l

213 s, as aberrant NOSTRIN expression leading to deactivation of the NFkappaB pathway, in turn triggering

214 of hydroxyl on the catalyst surface, whereas deactivation of the Pd-CoO/3DOM Co3O4 catalyst at high t

215 Increased deficits in deactivation of the posterior DMN in the T1D group were

216 mance under time pressure is associated with deactivation of the prefrontal cortex (PFC), an area imp

217 ransmitted to the other face, leading to the deactivation of the second potential binding site.

218 ly quantitative light-induced activation and deactivation of the vertebrate TRPA1 channel with violet

219 want to discuss their illness trajectory or deactivation of their ICD ever.

220 are characterized by sluggish activation and deactivation of their light responses.

221 p53 is an important tumor-suppressor protein deactivation of which by mdm2 results in cancers.

222 , and detailed mechanistic studies revealed "deactivation" of effector proteins such as Akt, Erk1/2,

223 (1) general emotional arousal (activation vs deactivation) or (2) specific emotion categories (fear v

224 However, preclusion of SNr deactivation, or direct inhibition of SNr fibers in the

225 motor cortex, children who stutter exhibited deactivation over these left hemisphere regions.

226 Importantly, this deactivation pathway is strongly dependent on particle d

227 of catalyst concentration, consistent with a deactivation pathway that is dependent on methanol conce

228 s believed to serve only as a major catalyst deactivation pathway to be avoided.

229 A catalyst deactivation pathway was identified, involving the forma

230 dditionally, solvent polarity influences the deactivation pathway, greatly affecting the strength of

231 ity of this so-far underappreciated catalyst deactivation pathway.

232 The (5) MC state is not involved in the deactivation pathway.

233 (eta(5)-C(5)Me(5))(4)Rh(5)H(7)] serving as a deactivation pathway.

234 t a synthetic strategy that blocks the major deactivation pathway: excited-state trans-to-cis polyene

235 Yet, few deactivation pathways are well understood.

236 ; d) Characterization of multiple activation/deactivation pathways of MOR, and e) Suggestion from cal

237 tant insights associated with the underlying deactivation pathways of the adsorbents upon exposure to

238 n considered as one of the major competitive deactivation pathways to transform excitation energy int

239 resence of the B3N3 rings engages additional deactivation pathways, possibly involving excited states

240 is type are potentially involved in catalyst deactivation pathways.

241 ations of the superordinate brain activation/deactivation pattern, each emphasizing different context

242 ciated with a superordinate brain activation/deactivation pattern, explained the majority of the vari

243 m temperature, and their rapid excited-state deactivation precludes their use as photosensitizers.

244 These findings suggest that the primary deactivation process consists of the loss of active site

245 are affected by both catalyst activation and deactivation processes occurring alongside the main reac

246 particle level, catalytic nanomaterials and deactivation processes under operando conditions that wi

247 f reactions suffering catalyst activation or deactivation processes.

248 reactions involving catalyst activation and deactivation processes.

249 t allows the estimation of the activation or deactivation profile of the catalyst when the order of t

250 bacteria-mediated iron-catalysed reversible deactivation radical polymerisation (RDRP), with a range

251 arnessing metal-free photoinduced reversible-deactivation radical polymerization (photo-RDRP) in orga

252 of polymerization techniques, of reversible deactivation radical polymerization, and provide a forwa

253 sistent with these observations, the glycine deactivation rate is slower in the presence of calcium-c

254 enhancing the sensitivity and prolonging the deactivation rate of A(1)R-GIRK signaling.

255 es from dentate granule cells demonstrated a deactivation rate of delta receptors similar to that of

256 the voltage dependence of activation and the deactivation rate of mutant channel currents were charac

257 or the relativistic enhancement of radiative deactivation rate processes, especially if Bi-based s-or

258 compromised by mutations that increase this deactivation rate.

259 Glutamate deactivation rates were unaffected.

260 ous delta IPSCs are mainly driven by channel deactivation, rather than by diffusion of GABA.

261 a-F elimination is not an important catalyst deactivation reaction in this system.

262 how that the metals resisted aggregation and deactivation, remaining atomically dispersed and accessi

263 Mast cell deactivation resulted in reduced inflammation, consequen

264 The dynamic interplay of activation and deactivation results in a material of which the behavior

265 In addition to the known ERK deactivation, retinoschisin treatment of retinoschisin-d

266 successfully apply protic CTAs in reversible-deactivation ring-opening copolymerizations (RD-ROCOP),

267 This deactivation route is remarkably fast, leading to severe

268 o this suppression because their optogenetic deactivation significantly altered the functional impact

269 Finally, the deactivation step is contingent upon the oxidation of th

270 mulations, we propose the following catalyst deactivation steps: (1) detachment of Cu(II) ions from c

271 Results of the 28-day deactivation study showed that on average, more than 94.

272 Desorption was evaluated by exposing the deactivation system to wash-out solutions.

273 Here application of a pharmacogenetic deactivation technique enabled us to investigate the mne

274 )beta2gamma2 receptors also exhibited faster deactivation than their WT counterparts, revealing that

275 ponent hemispheric pattern of activation and deactivation that depends on the availability of interau

276 itability contributes to the functional mPFC deactivation that is causal for the pain phenotype and r

277 that drive leukemia regulomes, as well as TF deactivations that alter host T cells in CTCL patients.

278 f continuous-flow reactors, and promotion of deactivation through addition of LiBr are critical to pr

279 the catalyst resting state and (v) catalyst deactivation through protonation.

280 depolarized potentials with no change on the deactivation time constant.

281 2D(Leu670Phe) variant slows current response deactivation time course and increased charge transfer.

282 otencies, open probability and the glutamate deactivation time course of GluN1/2B/2D receptors are in

283 s hippocampal slices also showed a prolonged deactivation time course.

284 Using cylinder deactivation to reduce the excess air ratio, lambda, and

285 thesis of electron-rich olefins, despite its deactivation toward hydrocarbon olefins.

286 e, the electrode was remarkably resistant to deactivation via coking caused by solid carbonaceous spe

287 ions, which leads to efficient nonradiative deactivation via metal-centered states.

288 ome antihyperlipidemics may inhibit warfarin deactivation via the hepatic cytochrome P450 system.

289 atches were impaired in mutant receptors, as deactivation was approximately 10- and 7-fold faster for

290 Moreover, the rate of deactivation was notably reduced due to prevention of CO

291 Motor unit deactivation was only observed during OCC (P < 0.001).

292 Deactivation was performed by mixing the medication, act

293 To estimate the rate of myosin deactivation, we followed the rate of the intensity reco

294 These deactivations were associated with reduced HRV, greater

295 aced suturing, and ventrolateral PFC (VLPFC) deactivations were identified during time-pressured sutu

296 l activation and reduced posterior cingulate deactivation, whereas OCD patients showed temporoparieta

297 aC helix is highly disordered, a hallmark of deactivation, whereas the BRI1 alphaC helix is moderatel

298 the amplitude of hERG current and speeds up deactivation, which can alter cardiac excitability.

299 2Me, Cl, Br, and CN, indicative of alpha-CH2 deactivation with HAT that predominantly occurs from the

300 med decision-making predicts VLPFC and DLPFC deactivation (z = -2.62, P < 0.05).