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1 een available to treat patients with severe, debilitating symptoms of obsessive-compulsive disorder (
2 disease (SCD) is an inherited, progressively debilitating blood disorder.
3     Osteoarthritis is a highly prevalent and debilitating joint disorder.
4 ssible routes to treatment for these common, debilitating brain disorders.
5 deposition as amyloid fibrils underlies many debilitating human disorders.
6 tunities for the treatment and prevention of debilitating anxiety disorders.
7 sive neurodegenerative disease that causes a debilitating movement disorder.
8 eutic strategies for protection against this debilitating movement disorder.
9 r the treatment of many life-threatening and debilitating vascular disorders.
10          Irritable bowel syndrome (IBS) is a debilitating and costly disorder.
11       Schizophrenia is a common, severe, and debilitating psychiatric disorder.
12                      Depression is a common, debilitating, and costly disorder.
13 isorder (MDD) is among the most frequent and debilitating psychiatric disorders.
14 nt and encompass the cellular substrates for debilitating degenerative disorders.
15 could revolutionize the way clinicians treat debilitating neurological disorders.
16 ion of its barriers can result in severe and debilitating neurological disorders.
17 ctions, and they are affected by a number of debilitating neurological disorders.
18 hizophrenia is one of the most pervasive and debilitating aspects of the disorder.
19 opment or maintenance in adulthood result in debilitating neuromuscular disorders.
20 ressive Pseudo Rheumatoid Dysplasia (PPRD) a debilitating musculoskeletal disorder.
21   Schizophrenia is among the most severe and debilitating of psychiatric disorders.
22 on or its regenerative properties results in debilitating musculoskeletal disorders.
23 nce, ENS dysfunction is linked to a range of debilitating gastrointestinal disorders.
24  exciting and powerful future treatments for debilitating mood and anxiety disorders.
25                Parkinson's disease (PD) is a debilitating neurodegenerative disorder.
26 e that confers increased risk for a range of debilitating neuropsychiatric disorders.
27 ion is a fundamental step in alleviating the debilitating symptoms of mood disorders.
28 us closer to identifying treatments for this debilitating neurodevelopmental disorder.
29 ates may therefore provide insight into this debilitating human developmental disorder.
30 epressive illness is a common and frequently debilitating familial psychiatric disorder.
31                          Cohesinopathies are debilitating human developmental disorders.
32  infants and 6 infants affected with equally debilitating, non-SMA denervating disorders.
33     Hepatic encephalopathy is a frequent and debilitating complication of liver disorders.
34 al manifestations range from none to severe, debilitating, and life-threatening disorders.
35  identification of novel treatments for this debilitating, currently untreatable disorder.
36                     Parkinson's disease is a debilitating, age-associated movement disorder.
37                       Parkinson disease is a debilitating and incurable neurodegenerative disorder af
38                Alzheimer's disease (AD) is a debilitating neurodegenerative disorder affecting millio
39                                Migraine is a debilitating neurological disorder affecting around one
40                      Rett syndrome (RS) is a debilitating neurological disorder affecting mostly girl
41 at between cannabis use and schizophrenia, a debilitating psychiatric disorder affecting ~1% of the p
42             AD has long been one of the most debilitating chronic neurological disorders, affecting m
43 n in metazoans, whereas dysfunction leads to debilitating developmental disorders and cancers.
44 lzheimer's disease (AD) is a progressive and debilitating neurodegenerative disorder and one of the l
45 he cognitive deficits often observed in many debilitating neurological disorders and diseases and in
46    Axonal degeneration is a hallmark of many debilitating neurological disorders and is thought to be
47 al cord injury (SCI) remains one of the most debilitating neurological disorders and the majority of
48 tment of one of the most severe and socially debilitating psychiatric disorders and open an exciting
49 atic stress disorder (PTSD) is a complex and debilitating anxiety disorder, and, although prolonged e
50                           DYT1 dystonia is a debilitating neurological movement disorder, and it repr
51     Addiction to heroin and crack cocaine is debilitating and persistent, but such disorders are trea
52                        However, because many debilitating human disorders are genetically complex, ph
53 r decades; however, the exact causes of this debilitating neuropsychiatric disorder are still unknown
54                           DYT1 dystonia is a debilitating neurological movement disorder arising from
55 Schizophrenia (SCZ) and bipolar disorder are debilitating neuropsychiatric disorders arising from a c
56                     Alzheimer's disease is a debilitating neurodegenerative disorder associated with
57 ress disorder (PTSD) is both a prevalent and debilitating trauma-related disorder associated with dys
58 E6) gene that cause Christianson syndrome, a debilitating X-linked developmental disorder associated
59      Trigeminal neuropathic pain is the most debilitating pain disorder but current treatments includ
60        N-glycanase 1 (NGLY1) deficiency is a debilitating, ultra-rare autosomal recessive disorder ca
61                                    DYT1 is a debilitating movement disorder caused by loss-of-functio
62  respiratory papillomatosis (RRP) is a rare, debilitating neoplastic disorder caused by chronic infec
63                Parkinson's disease (PD) is a debilitating neurodegenerative disorder caused by the lo
64                  Angelman syndrome (AS) is a debilitating neurodevelopmental disorder caused by loss
65                     Rett syndrome (RTT) is a debilitating neurodevelopmental disorder caused by mutat
66            Traumatic brain injury (TBI) is a debilitating neurological disorder caused by an impact t
67                       Angelman Syndrome is a debilitating neurological disorder caused by mutation of
68                     Rett syndrome (RTT) is a debilitating neurological disorder caused by mutations i
69  Retinitis Pigmentosa (RP) is a progressive, debilitating visual disorder caused by mutations in a di
70                        Mucolipidosis IV is a debilitating developmental lysosomal storage disorder ch
71 c cluster headache is an uncommon but highly debilitating primary headache disorder characterised by
72 prototypic systemic autoimmune disease, is a debilitating multisystem autoimmune disorder characteriz
73 mas comprise a heterogeneous group of highly debilitating and painful disorders characterized by thic
74                     Panic disorder (PD) is a debilitating anxiety disorder characterized by episodes
75                 Thyroid eye disease can be a debilitating autoimmune disorder characterized by progre
76        Tuberous Sclerosis Complex (TSC) is a debilitating developmental disorder characterized by a v
77 ents with chronic beryllium disease (CBD), a debilitating granulomatous lung disorder characterized b
78           Hidradenitis suppurativa (HS) is a debilitating inflammatory skin disorder characterized by
79                     Farber disease (FD) is a debilitating lysosomal storage disorder characterized by
80  Stress is a key risk factor for dystonia, a debilitating motor disorder characterized by cocontracti
81                 Expanded CAG repeats lead to debilitating neurodegenerative disorders characterized b
82                       Cocaine addiction is a debilitating neuropsychiatric disorder characterized by
83 y serve as transdiagnostic endophenotypes of debilitating neuropsychiatric disorders characterized by
84  (MDs) and inflammatory myopathies (IMs) are debilitating skeletal muscle disorders characterized by
85 nic spontaneous urticaria (CSU) is a common, debilitating skin disorder characterized by recurring ep
86 disorders, including psoriasis, a common and debilitating T-cell-driven disorder characterized by thi
87  stress disorder (PTSD) is a maladaptive and debilitating psychiatric disorder, characterized by re-e
88   Despite scientific advances, this chronic, debilitating, and life-limiting disorder continues to ca
89 r actions and shape our identities, and many debilitating memory disorders currently lack effective t
90 entally facile model in which to study these debilitating and currently treatment-refractory disorder
91                 Multiple sclerosis (MS) is a debilitating neuroimmunological and neurodegenerative di
92                                         Many debilitating neuropsychiatric and neurodegenerative diso
93 use mucolipidosis type IV (MLIV), a severely debilitating, autosomal recessive, lysosomal storage dis
94  la Tourette syndrome (GTS) is a potentially debilitating neuropsychiatric disorder defined by the pr
95 (ALS) and frontotemporal dementia (FTD), two debilitating neurodegenerative disorders driven in part
96  implicated in the pathology of a variety of debilitating human disorders (e.g., Alzheimer's disease,
97                  Cushing's disease is a rare debilitating endocrine disorder for which few prospectiv
98 erparathyroidism is a common and potentially debilitating endocrine disorder for which surgery is the
99 parathyroidism is a frequent and potentially debilitating endocrine disorder for which surgery is the
100      Mitochondrial DNA (mtDNA) defects cause debilitating metabolic disorders for which there is no e
101                           Stroke is a highly debilitating, often fatal disorder for which current the
102 cted by or involved in the etiology of these debilitating and progressive disorders has been understu
103           Hidradenitis suppurativa (HS) is a debilitating follicular skin disorder in which bacterial
104                                 CHIKV causes debilitating musculoskeletal disorders in humans that ar
105 age into mitochondria, a condition linked to debilitating neuromuscular disorders in humans.
106                 Social anxiety disorder is a debilitating, highly prevalent disorder in children and
107 on the relationship of obesity to common and debilitating hepatic and gastrointestinal disorders, inc
108                                 Anxiety is a debilitating symptom of most psychiatric disorders, incl
109 poor response to treatment of many patients, debilitating affective disorders (other disorders includ
110 ins are linked via pathology and genetics to debilitating degenerative disorders, including amyotroph
111 vated NF-kappaB has been observed in several debilitating inflammatory disorders, including rheumatoi
112 s of neurons with age underlies a variety of debilitating neurological disorders, including Alzheimer
113 ering the root causes of a broad spectrum of debilitating neuropsychiatric disorders, including anxie
114 somal/endosomal protein, to a broad range of debilitating human disorders indicates a shared fibrilli
115  immune signaling on the development of this debilitating psychological disorder is not known.
116 TEMENT Trigeminal neuropathic pain, the most debilitating pain disorder, is often triggered and exace
117 S) and are twice as likely as men to develop debilitating, stress-associated disorders later in life,
118                           Schizophrenia is a debilitating psychiatric disorder, leading to both physi
119 ansmission is strongly implicated in several debilitating conditions such as panic disorder, major de
120     Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder marked by progre
121        Inflammatory bowel disease (IBD) is a debilitating chronic inflammatory disorder of the intest
122                 Isolated focal dystonia is a debilitating movement disorder of unknown pathophysiolog
123 dder pain syndrome (IC/BPS) is a chronic and debilitating pain disorder of the bladder and urinary tr
124 ell adhesion molecule L1 (L1CAM) result in a debilitating X-linked congenital disorder of brain devel
125  of better pro-resolving strategies to treat debilitating complications of disorders ranging from inf
126                                     Numerous debilitating human disorders result from protein misfold
127 ons in S1P are involved in the prevalent and debilitating hemolytic disorder sickle cell disease (SCD
128     Sensory hypersensitivity is a common and debilitating feature of neurodevelopmental disorders suc
129 hreat processing is central to understanding debilitating fear- and trauma-related disorders such as
130 mechanism best known for its connection with debilitating human disorders such as Alzheimer's disease
131 tuitary-adrenal (HPA) axis activity leads to debilitating neuroendocrine or metabolic disorders such
132 or axonal functions, and its damage leads to debilitating neurological disorders such as multiple scl
133 dysfunction of REM sleep mechanisms underlie debilitating sleep disorders such as REM sleep behaviour
134 r postural control of the head-neck can be a debilitating symptom of neurological disorders such as a
135 lular homeostasis of these metals results in debilitating and frequently fatal human disorders, such
136 ion in patients with geriatric depression, a debilitating and increasingly prevalent disorder that ha
137 h can last for sustained periods, leading to debilitating chronic disorders that negatively impact qu
138                           This is a chronic, debilitating gastrointestinal disorder that affects rumi
139 ativa (HS), also known as acne inversa, is a debilitating inflammatory skin disorder that is characte
140                   Lipid storage diseases are debilitating inherited metabolic disorders that stem fro
141 raumatic stress disorder (PTSD) is a common, debilitating mental disorder that has been associated wi
142                         PTSD is a common and debilitating mental disorder that imposes a significant
143                Parkinson's disease (PD) is a debilitating movement disorder that afflicts >1 million
144     Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disorder that results in
145  STATEMENT Traumatic brain injury (TBI) is a debilitating neurological disorder that can seriously im
146                                The number of debilitating neurological disorders that occur when myel
147                        Cluster headache is a debilitating primary headache disorder that affects appr
148                   Depression is a common and debilitating psychiatric disorder that is associated wit
149   Post-traumatic stress disorder (PTSD) is a debilitating psychological disorder that also presents w
150       Duchenne muscular dystrophy (DMD) is a debilitating X-linked disorder that is fatal.
151            Opioid use disorder is a chronic, debilitating, and costly disorder that has increased in
152 The spinal cord is the site of many chronic, debilitating, neurological disorders that may be amenabl
153                Fragile X syndrome (FXS) is a debilitating neurodevelopmental disorder thought to aris
154                           Schizophrenia is a debilitating neuropsychiatric disorder typically diagnos
155 me individuals succumb to stress and develop debilitating psychiatric disorders, whereas others adapt
156                           Schizophrenia is a debilitating familial neuropsychiatric disorder which af
157    Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder which results in delet
158                                Dystonia is a debilitating hyperkinetic movement disorder, which can b
159 son's disease (PD) is one of the most highly debilitating neurodegenerative disorders, which affects
160                     Alzheimer's disease is a debilitating neurodegenerative disorder whose pathology
161               Sickle cell disease (SCD) is a debilitating monogenic blood disorder with a highly vari
162                  Bipolar disorder (BPD) is a debilitating mood disorder with an unclear etiology.
163                           Holmes tremor is a debilitating movement disorder with limited treatment op
164           Frontotemporal dementia (FTD) is a debilitating neurodegenerative disorder with currently n
165                    Schizophrenia (SCZD) is a debilitating neurological disorder with a world-wide pre
166               Migraine with aura is a severe debilitating neurological disorder with few relatively s
167                                Migraine is a debilitating neurological disorder with significant impa
168     Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric disorder with a genetic ri
169                     Schizophrenia (SCZ) is a debilitating neuropsychiatric disorder with high heritab
170                     Schizophrenia (SCZ) is a debilitating psychiatric disorder with a large genetic c
171    Posttraumatic stress disorder (PTSD) is a debilitating psychiatric disorder with a lifetime preval
172                           Schizophrenia is a debilitating psychiatric disorder with approximately 1%
173  Hidradenitis suppurativa (HS) is a chronic, debilitating, inflammatory skin disorder with a prevalen
174       Migraine is one of the most common and debilitating neurological disorders worldwide.
175 matic stress disorder (PTSD) is a common and debilitating mental disorder, yet a comprehensive networ

 
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