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1 cleavage of the 2',5' linkage by recombinant debranching enzyme.
2 eletion of DBR1, which encodes an RNA lariat debranching enzyme.
3 or to genes up-regulated by deletion of the debranching enzyme.
4 Pullulanase is a well-known starch-debranching enzyme.
5 pyrophosphorylase, and starch branching and debranching enzymes.
7 which inborn errors of the human RNA lariat-debranching enzyme 1 (DBR1) underlie brainstem viral enc
9 ells lacking both SpPrp18 and SpDbr1 (lariat debranching enzyme), a genetic background suitable for d
10 n accumulation when the only isoamylase-type debranching enzyme activity present is ISA1/ISA heterome
12 haracterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-alpha-glucan
13 haracterized by a deficiency in the glycogen debranching enzyme, amylo-1,6-glucosidase,4-alpha-glucan
16 form of a lariat and rapidly targeted by the debranching enzyme and nuclear exonucleases for lineariz
17 osin binding protein C (C-protein), glycogen debranching enzyme and ryanodine receptor 2 were also id
18 These data indicate that isoamylase-type debranching enzyme and SSIII work in a coordinated fashi
19 ene with sequence similarity to higher plant debranching enzymes, and both mutants lacked a chloropla
21 h/glycogen synthases, branching enzymes, and debranching enzymes) are differentially expressed in Mul
22 ity is that specific SSs, BEs, and/or starch debranching enzymes associate physically with each other
23 structure of the complex between the starch debranching enzyme barley limit dextrinase (LD), hydroly
24 t an enzyme of analogous nature to the plant debranching enzyme but of a different bacterial origin w
25 Saccharomyces cerevisiae, the absence of the debranching enzyme causes these lariat RNAs to accumulat
26 tered by mutations of isoamylase-type starch-debranching enzymes (DBE), although how these proteins a
28 ific isoamylase- and pullulanase-type starch-debranching enzymes (DBEs) present in developing maize (
30 investigations of group II intron splicing, debranching enzyme (Dbr) activity, and other biochemical
31 he 2',5'-bonds must be hydrolyzed by the RNA debranching enzyme Dbr1 before spliced introns can be de
34 TDN1 C-terminal region directly binds lariat debranching enzyme DBR1, whereas its N-terminal intrinsi
35 on in DBR1 (p.D262Y) encoding the RNA lariat-debranching enzyme DBR1, which is involved in the remova
36 ng new BP data from RNA sequencing of lariat debranching enzyme DBR1-mutated patients and from machin
39 spliceosome must be hydrolyzed by the intron debranching enzyme (Dbr1) before they can be metabolized
40 tudies in our laboratory showed that the RNA debranching enzyme (DBR1) is not required for early step
41 rpin RNA (shRNA) knockdown of the RNA lariat debranching enzyme (DBR1) led to a decrease in the produ
42 One of these host factors is the RNA lariat debranching enzyme (Dbr1), which cleaves the 2'-5' bond
46 e show that c-di-GMP also binds the glycogen-debranching-enzyme, GlgX, uncovering a direct link betwe
47 eals from a need for effective inhibition of debranching enzymes having characteristic open active si
49 , starch branching enzymes (BEs), and starch debranching enzymes; however, the molecular explanation
51 r abundance of oligosaccharide degrading and debranching enzymes in buffalo rumen metagenome and that
52 our goal was to evaluate the role of starch debranching enzymes in the determination of the structur
58 indirect evidence that the heteromultimeric debranching enzyme ISA1-ISA2 is not involved in starch b
63 SS2, and SS3 (to vary chain lengths) and the debranching enzyme ISOAMYLASE1-ISOAMYLASE2 (ISA; to alte
65 ose pyrophosphorylase, starch synthases, and debranching enzymes, leading to varied chain lengths and
66 G (type 1 phosphatase-targeting subunit), or debranching enzyme, making it unlikely that these protei
69 addition of pregelatinized starch and starch-debranching enzymes produced by far the highest amount o
71 -fold increase in the activity of the starch debranching enzyme, pullulanase (limit dextrinase), the
72 enes encoding granule-bound starch synthase, debranching enzymes, pullulanase, and starch phosphoryla
73 that gene expression of LIMIT DEXTRINASE1, a debranching enzyme that cleaves branch points within sta
74 yces cerevisiae Dbr1 is a 405-amino acid RNA debranching enzyme that cleaves the 2'-5' phosphodiester
75 I, SBEIIb, and sugary1, the putative starch-debranching enzyme, were each highly enriched in the amy
77 action of the splicing machinery and lariat-debranching enzyme, which yield pre-miRNA-like hairpins.
78 rotein with domains characteristic of lariat debranching enzymes, which has been named AtDBR1 (for Ar