ライフサイエンスコーパス: decalin

1 = 74:1; 3 degrees :2 degrees = 100:1 for cis-decalin).

2 gies provided the desired C16-epimeric trans-decalin.

3 tivity, resulting in sole [1,3]-shifts under decalin.

4 del substrate accessed from unfunctionalized decalin.

5 significantly more pronounced in xylene and decalin.

6 e, allows access to the diastereomeric trans-decalin.

7 ically pure form starting from 1,5-diaza-cis-decalin.

8 th diastereomers of an all-silicon analog of decalin.

9 oindene bicyclic core, rather than the usual decalin.

10 n the preparation of heavily substituted cis-decalins.

11 xclusively to cis-octalins, hydrindanes, and decalins.

12 mational switching is not observed for these decalins.

13 the equilibrium of substituted 1,5-diaza-cis-decalins.

14 c [5.6.6.5] systems such as dicyclopenta[b,g]decalins 37, 38, and 40 were prepared from similar diene

15 The highest activity is shown by decalin 9, which features N-(3,5-bis(trifluoromethyl)phe

16 e conformational equilibria of 1,5-diaza-cis-decalins, a new class of chiral diamine ligands, has bee

17 e ready access to 13 new cis-hydrindanes/cis-decalins, a protecting group-free total synthesis of an

18 Remarkably the hydroxylation of cis-decalin and 1,4-dimethylcyclohexane proceeds with retent

19 Comparison of the dimerization energies of decalin and perhydrocoronene with those of the naphthale

20 The flexible aliphatic region between the decalin and side chain portion of the natural product wa

21 n aryl ethers catalyzed by Ni was studied in decalin and water.

22 sis increases in the order Pd<Rh<Ir<Ru~Pt in decalin and water; the inverse was observed for the sele

23 distinct ruthenium and palladium catalysts, decalins and 7,6-bicycles can be obtained with dichotomo

24 itrile carbon, even in angularly substituted decalins and hydrindanes.

25 yclizations to cis and trans hydrindanes and decalins and provides key insight into the geometrical r

26 The 7-substituted 1-aza-cis-decalins are more likely to adopt the N-in form than the

27 of Darco KB, as the metal-free catalyst, and decalin, as the solvent in a closed vessel, represents t

28 d with that of the naked polyyne dumbbell in decalin at 80 degrees C, and the nanohoop rotaxane was f

29 The strongest bases are the decalin base 25 and the adamantane base 31.

30 The cis-decalin based gamma-amino alcohols, 1-5, were synthesize

31 fects were observed while in TCB, o-DCB, and decalin both components dissolve simultaneously.

32 n performed to investigate the mechanisms of decalin breakdown, and the Rice-Ramsperger-Kassel-Marcus

33 ompound, an unnatural diastereomer, and of a decalin building block was studied in detail using circu

34 ations of substituted cyclohexanes and trans-decalins by dimethyldioxirane (DMDO) were investigated c

35 more selective (ca. 75 %) than reactions in decalin (ca. 30 %).

36 Copper(I) and copper(II) 1,5-diaza-cis-decalin complexes [(N2)Cu] are effective precatalysts fo

37 2Zn alters the equilibrium to favor the N-in decalin conformer.

38 enolic coupling using a chiral 1,5-diaza-cis-decalin copper catalyst.

39 ns employing 2.5-10 mol % of a 1,5-diaza-cis-decalin copper(II) catalyst with oxygen as the oxidant,

40 ereocenters at both the halogenated benzoate-decalin core and the distal VBC of 3 and 4.

41 ls-Alder cycloaddition that led to the trans-decalin core of neo-clerodane diterpenoids are described

42 specific route to one enantiomer of a common decalin core that is present in numerous highly oxygenat

43 ted cyclohexenes including new hydrindan and decalin derivatives with good to excellent diastereosele

44 Several novel hydroxylated cis-decalin derivatives, potential intermediates for the syn

45 oid natural products with the trans-transoid decalin-dihydrobenzopyran ring system, which display a r

46 ctive transformation set the stage for trans-decalin formation and a late-stage Suarez oxidation that

47 ude a Diels-Alder reaction to generate a cis-decalin framework, followed by semipinacol-type ring con

48 ruction of angularly substituted trans-fused decalins from acyclic precursors.

49 exanol and cyclohexene in the apolar solvent decalin has been studied using in situ (13)C MAS NMR spe

50 Chiral 1,5-diaza-cis-decalins have been examined as ligands in the enantiosel

51 yl- and N,N'-bistrifluoroethyl-1,5-diaza-cis-decalins have been synthesized, and the equilibrium mixt

52 ation of 14,15-epoxy-3'-GGI, producing a new decalin IDT.

53 ce of the rate on H(2) chemical potential in decalin indicate that addition of H to the aromatic ring

54 Decalin is a classic example in the conformational analy

55 Carbocyclic decalin is a ubiquitous bicyclic structural motif.

56 formational flexibility of the 1,5-diaza-cis-decalins is analogous to (-)-sparteine such that these r

57 obtained (Delta ee = 92%) with 1,5-diaza-cis-decalin ligands differing only in the location of two me

58 ligand in this novel series, we show how the decalin locks the key selectivity-inducing cyclohexyl mo

59 ve manipulations delivered a fully decorated decalin moiety on large scale.

60 trategy include a facile construction of the decalin moiety that is produced via a stereoselective IM

61 The decalin moiety was established by a late-stage intramole

62 The construction of their trans-decalin motifs relied on two diastereochemically complem

63 With H(2)O(18), cis-decalin oxidation gave (18)O incorporation into the prod

64 zed, yielding variously functionalized spiro-decalin oxindoles with excellent stereoselectivity (>99:

65 of (-)-nahuoic acid Ci(Bii) (3), a novel cis-decalin polyketide, has been achieved.

66 1,5-Diaza-cis-decalin populates two conformations in which the nitroge

67 e ring system is converted to the target cis-decalin, preserving the integrity of the stereotriad.

68 thylcyclohexane, 1,4-dimethylcyclohexane and decalin provides a quantitative evaluation of the role p

69 , that selectively cyclize to cis- and trans-decalins, respectively.

70 d on the position of the substituents on the decalin ring system and the solvent.

71 fonium ion intermediate is formed as a trans-decalin ring system that can undergo glycosylation throu

72 hydroxylation of several eremophilane-type (decalin ring system) sesquiterpenes, such as with 5-epi-

73 tors, the sulfonium ion is formed as a trans-decalin ring system.

74 reaction is unique in that it provides a cis-decalin ring system; moreover, the yield of each of the

75 e radical cyclization to construct the trans-decalin ring, and a 6pi-electrocyclization/aromatization

76 tive alkene reduction to establish the trans-decalin ring, and carbonylative lactonization to install

77 C10-C11 double bond to produce the cis-fused Decalin S-germacrene A.

78 The structure-activity analysis revealed the decalin scaffold as the best moiety for the selectivity-

79 s featuring axial ureas on steroid and trans-decalin scaffolds can be especially effective.

80 ric Diels-Alder reaction to generate the cis-decalin skeleton, and a late-stage large fragment union

81 ns for the assembly of angularly substituted decalins--structural motifs that are ubiquitous in natur

82 r reaction that casted stereoselectively the decalin system and included the synthesis of six isomers

83 duce a 7/6 fused bicyclic system, provided a decalin system in contrast to ROM-RCM of the correspondi

84 de-based cyclization to form the trans-fused decalin system is described.

85 nt to the dienophile, which led to C4 of the decalin system, as well as the electron-withdrawing effe

86 icancer agent, taxodione (1) sharing a trans-decalin system.

87 n is accomplished by 1,6-addition of a trans-decalin tertiary radical with 4-vinylfuran-2-one.

88 The new pathways connect decalin to five primary monoaromatic species: benzene, t

89 en atom transfer (HAT) from cycloalkanes and decalins to the cumyloxyl radical (CumO(*)) were measure

90 pothesized to arise from a trans-multihetero-decalin transition state.

91 amine scaffolds: linear acenes, cyclohexane, decalin, triptycene, adamantane, and [2.2]paracyclophane

92 Decalin undergoes reaction with aluminum trichloride and

93 Decalin was fluorinated predominantly at the C2 and C3 m

94 is of functionalized cis-hydrindanes and cis-decalins was achieved using a sequential Diels-Alder/ald

95 3,7-substituted derivatives of 1,5-diaza-cis-decalins were designed to stabilize the conformational f

96 A series of amino alcohol- and diamino-cis-decalins were synthesized and their conformational prope

97 two conformational isomers of 1,5-diaza-cis-decalin while torsional effects appear to dominate the e

98 Chlorination of trans-decalin with 2 provided 95% selectivity for methylene-ch

99 lly, in the case of bi- and tricyclizations, decalins with cis stereochemistry have been obtained as